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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:cannabigerolic acid
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Accession:CHEBI:67081 term browser browse the term
Definition:A dihydroxybenzoic acid that is olivetolic acid in which the hydrogen at position 3 is substituted by a geranyl group. A biosynthetic precursor to Delta(9)-tetrahydrocannabinol, the principal psychoactive constituent of the cannabis plant.
Synonyms:exact_synonym: 3-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-2,4-dihydroxy-6-pentylbenzoic acid
 related_synonym: (E)-3-(3,7-Dimethyl-2,6-octadienyl)-2,4-dihydroxy-6-pentylbenzoic acid;   Formula=C22H32O4;   InChI=1S/C22H32O4/c1-5-6-7-11-17-14-19(23)18(21(24)20(17)22(25)26)13-12-16(4)10-8-9-15(2)3/h9,12,14,23-24H,5-8,10-11,13H2,1-4H3,(H,25,26)/b16-12+;   InChIKey=SEEZIOZEUUMJME-FOWTUZBSSA-N;   SMILES=CCCCCc1cc(O)c(C\\C=C(/C)CCC=C(C)C)c(O)c1C(O)=O
 xref: CAS:25555-57-1
 xref_mesh: MESH:C100679
 xref: MetaCyc:CPD-7166;   PMID:18283614;   PMID:18303850;   PMID:19704450;   PMID:21532172;   PMID:21726418;   PMID:22495534;   PMID:22766313;   PMID:22802619;   PMID:8663284;   PMID:9607329;   PMID:9862135;   Patent:GB2456183;   Patent:GB2468828;   Patent:US2011021617;   Patent:US2011038958;   Patent:WO2009087351;   Patent:WO2011017798;   Reaxys:2820770
 cyclic_relationship: is_conjugate_acid_of CHEBI:66962

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cannabigerolic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pparg peroxisome proliferator-activated receptor gamma increases expression
decreases expression
ISO cannabigerolic acid results in increased expression of PPARG mRNA
cannabigerolic acid results in decreased expression of PPARG protein
CTD PMID:28853159 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions
increases activity
ISO [cannabigerolic acid results in increased activity of TRPV1 protein] which results in increased uptake of Calcium CTD PMID:31096838 NCBI chr10:59,799,123...59,824,208
Ensembl chr10:59,799,123...59,824,679
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19883
    role 19833
      biological role 19833
        biochemical role 19370
          metabolite 19350
            olivetolic acid 10
              cannabigerolic acid 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19883
    subatomic particle 19881
      composite particle 19881
        hadron 19881
          baryon 19881
            nucleon 19881
              atomic nucleus 19881
                atom 19881
                  main group element atom 19771
                    p-block element atom 19771
                      carbon group element atom 19679
                        carbon atom 19668
                          organic molecular entity 19668
                            organic group 18580
                              organic divalent group 18571
                                organodiyl group 18571
                                  carbonyl group 18479
                                    carbonyl compound 18479
                                      carboxylic acid 18153
                                        aromatic carboxylic acid 10918
                                          benzoic acids 10887
                                            benzoic acid 3849
                                              hydroxybenzoic acid 3236
                                                dihydroxybenzoic acid 54
                                                  cannabigerolic acid 2
paths to the root