(+)-pilocarpine multiple interactions EXP 6480464 Plant Preparations inhibits the reaction [Pilocarpine results in decreased expression of GRIN1 mRNA] CTD PMID:18086456 (+)-pilocarpine decreases expression EXP 6480464 Pilocarpine results in decreased expression of GRIN1 mRNA CTD PMID:18086456 (25R)-cholest-5-ene-3beta,26-diol decreases expression EXP 6480464 27-hydroxycholesterol results in decreased expression of GRIN1 protein CTD PMID:18503570 (S)-3,5-dihydroxyphenylglycine multiple interactions EXP 6480464 6-methyl-2-(phenylethynyl)pyridine inhibits the reaction [N-(4-chloro-2-((1 more ... CTD PMID:16600209 (S)-3,5-dihydroxyphenylglycine increases phosphorylation EXP 6480464 3, 5-dihydroxyphenylglycine results in increased phosphorylation of GRIN1 protein CTD PMID:16600209 1,2-dichloroethane increases expression EXP 6480464 ethylene dichloride results in increased expression of GRIN1 protein CTD PMID:17456392 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine increases expression EXP 6480464 1-Methyl-4-phenyl-1 more ... CTD PMID:23538867 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine multiple interactions EXP 6480464 [mithramycin A co-treated with astaxanthine] inhibits the reaction [1-Methyl-4-phenyl-1 more ... CTD PMID:23538867 1-naphthyl isothiocyanate decreases expression EXP 6480464 1-Naphthylisothiocyanate results in decreased expression of GRIN1 mRNA CTD PMID:12832660 17beta-estradiol multiple interactions ISO RGD:10685 6480464 [[Lithium Chloride co-treated with Estradiol] results in decreased expression of GRIN1 mRNA] which affects the susceptibility to Excitatory Amino Acid Agonists, [Lithium Chloride co-treated with Estradiol] results in decreased expression of GRIN1 mRNA CTD PMID:19285052 17beta-estradiol multiple interactions EXP 6480464 Estradiol inhibits the reaction [Paraquat results in decreased expression of NMDAR1 protein] CTD PMID:31715309 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of GRIN1 protein CTD PMID:12411739 17beta-estradiol 3-benzoate multiple interactions EXP 6480464 fulvestrant inhibits the reaction [estradiol 3-benzoate results in increased phosphorylation of GRIN1 protein], U 0126 inhibits the reaction [estradiol 3-benzoate results in increased phosphorylation of GRIN1 protein] CTD PMID:21763338 17beta-estradiol 3-benzoate increases phosphorylation EXP 6480464 estradiol 3-benzoate results in increased phosphorylation of GRIN1 protein CTD PMID:21763338 2,2',4,4'-Tetrabromodiphenyl ether decreases expression EXP 6480464 2 more ... CTD PMID:22467012 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of GRIN1 mRNA, Tetrachlorodibenzodioxin results in decreased expression of GRIN1 protein CTD PMID:14984010 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:10685 6480464 Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to GRIN1 promoter] CTD PMID:19654925 2,3,7,8-Tetrachlorodibenzofuran decreases expression EXP 6480464 2 more ... CTD PMID:32109520 2,6-dinitrotoluene affects expression EXP 6480464 2, 6-dinitrotoluene affects the expression of GRIN1 mRNA CTD PMID:21346803 2-methyl-6-(phenylethynyl)pyridine multiple interactions EXP 6480464 6-methyl-2-(phenylethynyl)pyridine affects the reaction [Cocaine affects the phosphorylation of GRIN1 protein] more ... CTD PMID:16600209 , PMID:17680995 2-methylcholine affects expression ISO RGD:731784 6480464 beta-methylcholine affects the expression of GRIN1 mRNA CTD PMID:21179406 26-hydroxycholesterol decreases expression EXP 6480464 27-hydroxycholesterol results in decreased expression of GRIN1 protein CTD PMID:18503570 3,4-methylenedioxymethamphetamine increases expression ISO RGD:10685 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in increased expression of GRIN1 mRNA CTD PMID:20188158 3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione multiple interactions EXP 6480464 bisindolylmaleimide I inhibits the reaction [CARTPT protein results in increased phosphorylation of GRIN1 protein] CTD PMID:19632277 4-[1-hydroxy-2-[4-(phenylmethyl)-1-piperidinyl]propyl]phenol multiple interactions EXP 6480464 ifenprodil inhibits the reaction [Cocaine results in increased expression of GRIN1 protein] CTD PMID:19474322 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of GRIN1 mRNA CTD PMID:24780913 acrylamide increases expression EXP 6480464 Acrylamide results in increased expression of GRIN1 mRNA CTD PMID:28606764 aflatoxin B1 decreases methylation ISO RGD:731784 6480464 Aflatoxin B1 results in decreased methylation of GRIN1 gene CTD PMID:27153756 aflatoxin B2 decreases methylation ISO RGD:731784 6480464 aflatoxin B2 results in decreased methylation of GRIN1 intron CTD PMID:30157460 agmatine multiple interactions EXP 6480464 Agmatine inhibits the reaction [Morphine results in increased expression of GRIN1 protein] CTD PMID:20950603 aldehydo-D-glucose decreases expression ISO RGD:10685 6480464 Glucose results in decreased expression of GRIN1 mRNA CTD PMID:31525975 all-trans-retinoic acid multiple interactions ISO RGD:731784 6480464 [SN50 peptide affects the localization of [RELA protein binds to NFKB1 protein]] inhibits the reaction [Tretinoin results in increased expression of GRIN1 protein] CTD PMID:18280257 all-trans-retinoic acid affects expression ISO RGD:731784 6480464 Tretinoin affects the expression of GRIN1 mRNA CTD PMID:31600526 all-trans-retinoic acid increases expression ISO RGD:731784 6480464 Tretinoin results in increased expression of GRIN1 protein CTD PMID:18280257 ammonium chloride affects localization EXP 6480464 Ammonium Chloride affects the localization of GRIN1 protein CTD PMID:16678351 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of GRIN1 mRNA CTD PMID:16483693 ammonium chloride increases phosphorylation EXP 6480464 Ammonium Chloride results in increased phosphorylation of GRIN1 protein CTD PMID:16678351 amphetamine increases phosphorylation EXP 6480464 Amphetamine results in increased phosphorylation of GRIN1 protein CTD PMID:14622123 androgen antagonist multiple interactions EXP 6480464 [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of GRIN1 mRNA CTD PMID:25607892 arsenite(3-) increases methylation ISO RGD:731784 6480464 arsenite results in increased methylation of GRIN1 promoter CTD PMID:23974009 arsenite(3-) decreases expression ISO RGD:10685 6480464 arsenite results in decreased expression of GRIN1 mRNA, arsenite results in decreased expression of GRIN1 protein CTD PMID:31708534 arsenous acid decreases expression ISO RGD:10685 6480464 Arsenic Trioxide results in decreased expression of GRIN1 mRNA CTD PMID:24831965 astaxanthin multiple interactions EXP 6480464 [mithramycin A co-treated with astaxanthine] inhibits the reaction [1-Methyl-4-phenyl-1 more ... CTD PMID:23538867 benzo[a]pyrene increases expression ISO RGD:10685 6480464 Benzo(a)pyrene results in increased expression of GRIN1 mRNA CTD PMID:23684556 benzo[a]pyrene affects methylation ISO RGD:731784 6480464 Benzo(a)pyrene affects the methylation of GRIN1 intron CTD PMID:30157460 bis(2-ethylhexyl) phthalate decreases expression EXP 6480464 Diethylhexyl Phthalate results in decreased expression of GRIN1 mRNA CTD PMID:15518916 bis(2-ethylhexyl) phthalate multiple interactions EXP 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of GRIN1 mRNA CTD PMID:25607892 bisphenol A increases phosphorylation EXP 6480464 bisphenol A results in increased phosphorylation of GRIN1 protein CTD PMID:21763338 bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of GRIN1 gene CTD PMID:28505145 bisphenol A affects expression ISO RGD:10685 6480464 bisphenol A affects the expression of GRIN1 protein CTD PMID:23240141 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of GRIN1 mRNA, bisphenol A results in decreased expression of GRIN1 protein CTD PMID:20821433 more ... bisphenol A increases expression ISO RGD:10685 6480464 bisphenol A results in increased expression of GRIN1 protein CTD PMID:24333847 bisphenol A decreases expression ISO RGD:10685 6480464 bisphenol A results in decreased expression of GRIN1 protein CTD PMID:20206181 more ... bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of GRIN1 protein CTD PMID:12411739 bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of GRIN1 mRNA more ... CTD PMID:21763338 , PMID:25607892 Butylparaben multiple interactions EXP 6480464 [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of GRIN1 mRNA, [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of GRIN1 mRNA CTD PMID:25607892 C60 fullerene decreases expression EXP 6480464 fullerene C60 results in decreased expression of GRIN1 mRNA CTD PMID:19167457 cadmium dichloride increases methylation EXP 6480464 Cadmium Chloride results in increased methylation of GRIN1 promoter CTD PMID:22457795 cadmium dichloride affects expression ISO RGD:10685 6480464 Cadmium Chloride affects the expression of GRIN1 mRNA CTD PMID:29408670 capsaicin multiple interactions EXP 6480464 N-(2-(3 more ... CTD PMID:17317010 , PMID:20054487 capsaicin increases phosphorylation EXP 6480464 Capsaicin results in increased phosphorylation of GRIN1 protein CTD PMID:20054487 capsaicin increases expression EXP 6480464 Capsaicin results in increased expression of GRIN1 protein modified form CTD PMID:17317010 celecoxib multiple interactions ISO RGD:10685 6480464 Celecoxib promotes the reaction [Kainic Acid results in decreased expression of GRIN1 mRNA] CTD PMID:21589914 chlorpyrifos increases expression EXP 6480464 Chlorpyrifos results in increased expression of GRIN1 mRNA CTD PMID:19440498 choline multiple interactions EXP 6480464 Choline analog inhibits the reaction [lead acetate results in decreased expression of GRIN1 mRNA], Choline analog inhibits the reaction [lead acetate results in decreased expression of GRIN1 protein] CTD PMID:20381573 choline multiple interactions ISO RGD:10685 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of GRIN1 gene CTD PMID:20938992 clozapine decreases expression ISO RGD:10685 6480464 Clozapine results in decreased expression of GRIN1 mRNA CTD PMID:17266109 clozapine increases expression EXP 6480464 Clozapine results in increased expression of GRIN1 mRNA CTD PMID:12020038 , PMID:18923069 clozapine decreases expression EXP 6480464 Clozapine results in decreased expression of GRIN1 mRNA CTD PMID:12608697 cocaine multiple interactions EXP 6480464 6-methyl-2-(phenylethynyl)pyridine affects the reaction [Cocaine affects the phosphorylation of GRIN1 protein] more ... CTD PMID:11801363 more ... cocaine affects response to substance EXP 6480464 GRIN1 protein affects the susceptibility to Cocaine CTD PMID:11801363 cocaine increases expression EXP 6480464 Cocaine results in increased expression of GRIN1 mRNA, Cocaine results in increased expression of GRIN1 protein CTD PMID:11801363 more ... cocaine affects phosphorylation EXP 6480464 Cocaine affects the phosphorylation of GRIN1 protein CTD PMID:12457264 cocaine affects expression EXP 6480464 Cocaine affects the expression of GRIN1 mRNA, Cocaine affects the expression of GRIN1 protein CTD PMID:11032893 more ... cocaine decreases expression ISO RGD:10685 6480464 Cocaine results in decreased expression of GRIN1 mRNA CTD PMID:9886066 cocaine increases expression ISO RGD:731784 6480464 Cocaine results in increased expression of GRIN1 protein CTD PMID:16363995 Colforsin dapropate hydrochloride increases phosphorylation EXP 6480464 Colforsin results in increased phosphorylation of GRIN1 protein CTD PMID:14622123 Colforsin dapropate hydrochloride multiple interactions EXP 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased phosphorylation of GRIN1 protein] CTD PMID:14622123 copper atom multiple interactions EXP 6480464 [Copper co-treated with Dietary Sucrose] results in increased expression of GRIN1 mRNA CTD PMID:26033743 copper atom decreases expression ISO RGD:10685 6480464 Copper results in decreased expression of GRIN1 protein CTD PMID:25007851 copper atom multiple interactions ISO RGD:10685 6480464 Copper promotes the reaction [PRNP protein binds to GRIN1 protein] CTD PMID:22307640 copper(0) multiple interactions EXP 6480464 [Copper co-treated with Dietary Sucrose] results in increased expression of GRIN1 mRNA CTD PMID:26033743 copper(0) decreases expression ISO RGD:10685 6480464 Copper results in decreased expression of GRIN1 protein CTD PMID:25007851 copper(0) multiple interactions ISO RGD:10685 6480464 Copper promotes the reaction [PRNP protein binds to GRIN1 protein] CTD PMID:22307640 curcumin multiple interactions EXP 6480464 Curcumin inhibits the reaction [sodium arsenite results in decreased expression of GRIN1 mRNA] more ... CTD PMID:23267840 , PMID:29723552 cyclosporin A decreases methylation ISO RGD:731784 6480464 Cyclosporine results in decreased methylation of GRIN1 promoter CTD PMID:27989131 cyhalothrin decreases expression EXP 6480464 cyhalothrin results in decreased expression of GRIN1 mRNA, cyhalothrin results in decreased expression of GRIN1 protein CTD PMID:28487251 D-glucose decreases expression ISO RGD:10685 6480464 Glucose results in decreased expression of GRIN1 mRNA CTD PMID:31525975 DDE multiple interactions EXP 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of GRIN1 mRNA CTD PMID:25607892 decabromodiphenyl ether multiple interactions ISO RGD:10685 6480464 BESEB CDRI-08 inhibits the reaction [decabromobiphenyl ether inhibits the reaction [REST protein binds to GRIN1 promoter]] more ... CTD PMID:26413122 decabromodiphenyl ether decreases expression EXP 6480464 decabromobiphenyl ether results in decreased expression of GRIN1 protein CTD PMID:30404998 decabromodiphenyl ether increases expression ISO RGD:10685 6480464 decabromobiphenyl ether results in increased expression of GRIN1 mRNA CTD PMID:26413122 , PMID:29151189 dexamethasone decreases expression EXP 6480464 Dexamethasone results in decreased expression of GRIN1 mRNA CTD PMID:29111458 dextromethorphan increases expression EXP 6480464 Dextromethorphan results in increased expression of GRIN1 protein CTD PMID:28916251 diarsenic trioxide decreases expression ISO RGD:10685 6480464 Arsenic Trioxide results in decreased expression of GRIN1 mRNA CTD PMID:24831965 diazinon decreases expression ISO RGD:10685 6480464 Diazinon results in decreased expression of GRIN1 mRNA CTD PMID:23212306 dibutyl phthalate multiple interactions EXP 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of GRIN1 mRNA CTD PMID:25607892 dieldrin increases uptake ISO RGD:10685 6480464 Dieldrin results in increased uptake of GRIN1 protein CTD PMID:19812363 dieldrin increases expression EXP 6480464 Dieldrin results in increased expression of GRIN1 mRNA CTD PMID:19440498 dopamine multiple interactions EXP 6480464 [Dopamine results in increased activity of DRD1 protein] which results in increased phosphorylation of GRIN1 protein, N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[Dopamine results in increased activity of DRD1 protein] which results in increased phosphorylation of GRIN1 protein] CTD PMID:14622123 enzacamene multiple interactions EXP 6480464 [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of GRIN1 mRNA, [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of GRIN1 mRNA CTD PMID:25607892 epoxiconazole multiple interactions EXP 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of GRIN1 mRNA CTD PMID:25607892 ethanol increases expression EXP 6480464 Ethanol results in increased expression of GRIN1 mRNA, Ethanol results in increased expression of GRIN1 protein CTD PMID:12045474 , PMID:20655511 ethanol multiple interactions ISO RGD:10685 6480464 Ethanol affects the expression of and affects the splicing of GRIN1 mRNA CTD PMID:30319688 ethanol affects expression ISO RGD:10685 6480464 Ethanol affects the expression of GRIN1 mRNA CTD PMID:30319688 ethanol increases expression ISO RGD:10685 6480464 Ethanol results in increased expression of GRIN1 mRNA, Ethanol results in increased expression of GRIN1 protein CTD PMID:29800586 , PMID:30319688 ethanol decreases expression EXP 6480464 Ethanol results in decreased expression of GRIN1 mRNA CTD PMID:18713641 excitatory amino acid agonist multiple interactions ISO RGD:10685 6480464 [[Lithium Chloride co-treated with Estradiol] results in decreased expression of GRIN1 mRNA] which affects the susceptibility to Excitatory Amino Acid Agonists CTD PMID:19285052 excitatory amino acid agonist multiple interactions ISO RGD:731784 6480464 [GRIN1 protein co-treated with GRIN2A protein] results in increased susceptibility to Excitatory Amino Acid Agonists more ... CTD PMID:11812690 , PMID:19224577 felbamate multiple interactions EXP 6480464 felbamate results in decreased activity of [GRIN1 protein alternative form binds to GRIN2A protein] more ... CTD PMID:10690753 felbamate affects binding EXP 6480464 GRIN1 protein binds to felbamate CTD PMID:18311896 folic acid multiple interactions ISO RGD:10685 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of GRIN1 gene CTD PMID:20938992 folic acid multiple interactions EXP 6480464 Dizocilpine Maleate inhibits the reaction [Folic Acid deficiency results in increased expression of GRIN1 protein] CTD PMID:20406136 folic acid increases expression EXP 6480464 Folic Acid deficiency results in increased expression of GRIN1 protein CTD PMID:20406136 fulvestrant multiple interactions EXP 6480464 fulvestrant inhibits the reaction [bisphenol A results in increased phosphorylation of GRIN1 protein], fulvestrant inhibits the reaction [estradiol 3-benzoate results in increased phosphorylation of GRIN1 protein] CTD PMID:21763338 gamma-tocopherol increases expression ISO RGD:10685 6480464 Tocopherols results in increased expression of GRIN1 mRNA CTD PMID:17654050 genistein decreases expression ISO RGD:731784 6480464 Genistein results in decreased expression of GRIN1 mRNA CTD PMID:25136773 gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of GRIN1 mRNA, Gentamicins results in increased expression of GRIN1 protein CTD PMID:15200423 glucose decreases expression ISO RGD:10685 6480464 Glucose results in decreased expression of GRIN1 mRNA CTD PMID:31525975 haloperidol decreases expression EXP 6480464 Haloperidol results in decreased expression of GRIN1 mRNA CTD PMID:12020038 haloperidol increases expression EXP 6480464 Haloperidol results in increased expression of GRIN1 mRNA CTD PMID:12020038 herbicide decreases expression ISO RGD:10685 6480464 Herbicides results in decreased expression of GRIN1 mRNA CTD PMID:21318024 herbicide multiple interactions ISO RGD:10685 6480464 arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide inhibits the reaction [Herbicides results in decreased expression of GRIN1 mRNA] CTD PMID:21318024 homocysteine increases expression EXP 6480464 Homocysteine analog results in increased expression of GRIN1 protein CTD PMID:20406136 kainic acid multiple interactions ISO RGD:10685 6480464 celecoxib promotes the reaction [Kainic Acid results in decreased expression of GRIN1 mRNA] CTD PMID:21589914 kainic acid affects expression EXP 6480464 Kainic Acid affects the expression of GRIN1 CTD PMID:23159308 kainic acid decreases expression ISO RGD:10685 6480464 Kainic Acid results in decreased expression of GRIN1 mRNA CTD PMID:21589914 ketamine increases expression EXP 6480464 Ketamine results in increased expression of GRIN1 mRNA, Ketamine results in increased expression of GRIN1 protein CTD PMID:19126600 more ... KT 5720 multiple interactions EXP 6480464 KT 5720 inhibits the reaction [CARTPT protein results in increased phosphorylation of GRIN1 protein] CTD PMID:19632277 L-methionine multiple interactions ISO RGD:10685 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of GRIN1 gene CTD PMID:20938992 lead diacetate multiple interactions EXP 6480464 [lead acetate promotes the reaction [GRIN1 protein binds to GRIN2B protein]] which results in decreased phosphorylation of CREB1 protein more ... CTD PMID:12480136 , PMID:20381573 lead diacetate decreases expression ISO RGD:10685 6480464 lead acetate results in decreased expression of GRIN1 mRNA, lead acetate results in decreased expression of GRIN1 protein CTD PMID:24260418 , PMID:25242007 lead diacetate decreases expression EXP 6480464 lead acetate results in decreased expression of GRIN1 mRNA, lead acetate results in decreased expression of GRIN1 protein CTD PMID:20381573 , PMID:22160880 lead(0) affects localization EXP 6480464 Lead affects the localization of GRIN1 protein CTD PMID:21192972 lead(0) affects expression ISO RGD:731784 6480464 Lead affects the expression of GRIN1 mRNA CTD PMID:28903495 lead(2+) affects localization EXP 6480464 Lead affects the localization of GRIN1 protein CTD PMID:21192972 lead(2+) affects expression ISO RGD:731784 6480464 Lead affects the expression of GRIN1 mRNA CTD PMID:28903495 lead(II) chloride increases expression EXP 6480464 lead chloride results in increased expression of GRIN1 mRNA CTD PMID:19651682 linuron multiple interactions EXP 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of GRIN1 mRNA CTD PMID:25607892 lipoteichoic acid multiple interactions ISO RGD:10685 6480464 [Particulate Matter co-treated with lipoteichoic acid] results in increased expression of GRIN1 mRNA, [Vehicle Emissions co-treated with lipoteichoic acid] results in increased expression of GRIN1 mRNA CTD PMID:18926851 lithium chloride multiple interactions ISO RGD:10685 6480464 [[Lithium Chloride co-treated with Estradiol] results in decreased expression of GRIN1 mRNA] which affects the susceptibility to Excitatory Amino Acid Agonists, [Lithium Chloride co-treated with Estradiol] results in decreased expression of GRIN1 mRNA CTD PMID:19285052 lithium chloride decreases expression ISO RGD:10685 6480464 Lithium Chloride results in decreased expression of GRIN1 mRNA CTD PMID:19285052 manganese atom decreases expression EXP 6480464 Manganese results in decreased expression of GRIN1 mRNA, Manganese results in decreased expression of GRIN1 protein CTD PMID:19643132 , PMID:29205667 manganese(0) decreases expression EXP 6480464 Manganese results in decreased expression of GRIN1 mRNA, Manganese results in decreased expression of GRIN1 protein CTD PMID:19643132 , PMID:29205667 manganese(II) chloride decreases expression EXP 6480464 manganese chloride results in decreased expression of GRIN1 mRNA, manganese chloride results in decreased expression of GRIN1 protein CTD PMID:20175136 melamine decreases expression EXP 6480464 melamine results in decreased expression of GRIN1 protein CTD PMID:28206646 methamphetamine increases expression EXP 6480464 Methamphetamine results in increased expression of GRIN1 mRNA CTD PMID:18419818 methapyrilene decreases methylation ISO RGD:731784 6480464 Methapyrilene results in decreased methylation of GRIN1 intron CTD PMID:30157460 methoxychlor increases methylation EXP 6480464 Methoxychlor results in increased methylation of GRIN1 gene CTD PMID:23303685 methylmercury chloride decreases expression EXP 6480464 methylmercuric chloride results in decreased expression of GRIN1 mRNA, methylmercuric chloride results in decreased expression of GRIN1 protein CTD PMID:19651682 , PMID:22223486 methylmercury chloride multiple interactions EXP 6480464 Polyphenols inhibits the reaction [methylmercuric chloride results in decreased expression of GRIN1 mRNA], Polyphenols inhibits the reaction [methylmercuric chloride results in decreased expression of GRIN1 protein] CTD PMID:22223486 monosodium L-glutamate increases expression EXP 6480464 Sodium Glutamate results in increased expression of GRIN1 CTD PMID:15139026 morphine multiple interactions ISO RGD:10685 6480464 [Morphine results in increased activity of OPRM1 protein] which results in increased phosphorylation of GRIN1 protein, MMP9 protein affects the reaction [Morphine results in increased phosphorylation of GRIN1 protein] CTD PMID:17996026 , PMID:20519536 morphine increases expression EXP 6480464 Morphine results in increased expression of GRIN1 protein CTD PMID:20950603 , PMID:22713680 morphine multiple interactions EXP 6480464 Agmatine inhibits the reaction [Morphine results in increased expression of GRIN1 protein] more ... CTD PMID:20950603 , PMID:22713680 morphine decreases phosphorylation EXP 6480464 Morphine results in decreased phosphorylation of GRIN1 protein CTD PMID:15287884 morphine increases phosphorylation ISO RGD:10685 6480464 Morphine results in increased phosphorylation of GRIN1 protein CTD PMID:20519536 morphine affects phosphorylation ISO RGD:10685 6480464 Morphine affects the phosphorylation of GRIN1 protein CTD PMID:17996026 N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide multiple interactions EXP 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[2 more ... CTD PMID:14622123 nobiletin increases expression EXP 6480464 nobiletin results in increased expression of GRIN1 mRNA CTD PMID:24964900 Nonylphenol decreases expression EXP 6480464 nonylphenol results in decreased expression of GRIN1 mRNA CTD PMID:15518916 notoginsenoside R1 multiple interactions ISO RGD:731784 6480464 [GRIN1 protein co-treated with GRIN2B protein] results in increased susceptibility to notoginsenoside R1 CTD PMID:19224577 ochratoxin A multiple interactions ISO RGD:731784 6480464 [ochratoxin A results in increased acetylation of GRIN1 promoter] which results in increased expression of GRIN1 mRNA CTD PMID:29098329 ochratoxin A increases expression ISO RGD:731784 6480464 ochratoxin A results in increased expression of GRIN1 mRNA CTD PMID:29098329 ochratoxin A increases acetylation ISO RGD:731784 6480464 ochratoxin A results in increased acetylation of GRIN1 promoter CTD PMID:29098329 oxidopamine decreases expression EXP 6480464 Oxidopamine results in decreased expression of GRIN1 mRNA, Oxidopamine results in decreased expression of GRIN1 protein alternative form CTD PMID:15518916 , PMID:16365282 oxidopamine multiple interactions EXP 6480464 Levodopa inhibits the reaction [Oxidopamine results in decreased expression of GRIN1 protein alternative form] CTD PMID:16365282 oxybenzone affects expression EXP 6480464 oxybenzone affects the expression of GRIN1 protein CTD PMID:31368502 ozone multiple interactions ISO RGD:10685 6480464 [[Ozone results in increased oxidation of Particulate Matter] which results in increased chemical synthesis of Aerosols] which results in increased expression of GRIN1 mRNA, [[Ozone results in increased oxidation of Vehicle Emissions] which results in increased chemical synthesis of Aerosols] which results in increased expression of GRIN1 mRNA CTD PMID:25361045 paracetamol multiple interactions EXP 6480464 [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of GRIN1 mRNA CTD PMID:25607892 paraquat decreases expression EXP 6480464 Paraquat results in decreased expression of GRIN1 mRNA, Paraquat results in decreased expression of NMDAR1 protein CTD PMID:19146868 more ... paraquat multiple interactions EXP 6480464 Estradiol inhibits the reaction [Paraquat results in decreased expression of NMDAR1 protein] CTD PMID:31715309 parathion decreases expression EXP 6480464 Parathion results in decreased expression of GRIN1 mRNA CTD PMID:19146868 pentobarbital affects expression EXP 6480464 Pentobarbital affects the expression of GRIN1 mRNA CTD PMID:10717408 perfluorooctane-1-sulfonic acid affects expression EXP 6480464 perfluorooctane sulfonic acid affects the expression of GRIN1 mRNA, perfluorooctane sulfonic acid affects the expression of NMDAR1 mRNA CTD PMID:20136073 phencyclidine decreases expression ISO RGD:10685 6480464 Phencyclidine results in decreased expression of GRIN1 mRNA CTD PMID:17266109 phenytoin increases expression EXP 6480464 Phenytoin results in increased expression of GRIN1 mRNA CTD PMID:20345932 picloram multiple interactions ISO RGD:10685 6480464 arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide promotes the reaction [Picloram results in decreased expression of GRIN1 mRNA] CTD PMID:21318024 picloram decreases expression ISO RGD:10685 6480464 Picloram results in decreased expression of GRIN1 mRNA CTD PMID:21318024 prochloraz multiple interactions EXP 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of GRIN1 mRNA CTD PMID:25607892 procymidone multiple interactions EXP 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of GRIN1 mRNA CTD PMID:25607892 resveratrol multiple interactions EXP 6480464 resveratrol inhibits the reaction [Morphine results in increased expression of [GRIN1 protein binds to GRIN2B protein binds to DLG4 protein]], resveratrol inhibits the reaction [Morphine results in increased expression of GRIN1 protein] CTD PMID:22713680 resveratrol decreases expression EXP 6480464 resveratrol results in decreased expression of GRIN1 protein modified form CTD PMID:27093858 resveratrol multiple interactions ISO RGD:10685 6480464 [2-(4-morpholino)ethyl-1-phenylcyclohexane-1-carboxylate co-treated with resveratrol] affects the phosphorylation of GRIN1 protein CTD PMID:24885036 semicarbazide decreases activity ISO RGD:731784 6480464 carbamylhydrazine results in decreased activity of GRIN1 protein CTD PMID:19788891 SKF 38393 multiple interactions EXP 6480464 [2 more ... CTD PMID:14622123 sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of GRIN1 mRNA, sodium arsenite results in decreased expression of GRIN1 protein CTD PMID:29723552 sodium arsenite decreases expression ISO RGD:10685 6480464 sodium arsenite results in decreased expression of GRIN1 mRNA, sodium arsenite results in decreased expression of GRIN1 protein CTD PMID:31712840 sodium arsenite multiple interactions EXP 6480464 Curcumin inhibits the reaction [sodium arsenite results in decreased expression of GRIN1 mRNA], Curcumin inhibits the reaction [sodium arsenite results in decreased expression of GRIN1 protein] CTD PMID:29723552 streptozocin multiple interactions EXP 6480464 Curcumin inhibits the reaction [Streptozocin results in increased expression of GRIN1 mRNA] more ... CTD PMID:23267840 streptozocin increases expression EXP 6480464 Streptozocin results in increased expression of GRIN1 mRNA, Streptozocin results in increased expression of GRIN1 protein CTD PMID:23267840 sulfur dioxide decreases expression EXP 6480464 Sulfur Dioxide results in decreased expression of GRIN1 mRNA CTD PMID:25534910 sulindac affects expression EXP 6480464 Sulindac affects the expression of GRIN1 protein CTD PMID:15123337 thimerosal decreases expression ISO RGD:10685 6480464 Thimerosal results in decreased expression of GRIN1 protein CTD PMID:15184908 titanium dioxide decreases expression ISO RGD:10685 6480464 titanium dioxide results in decreased expression of GRIN1 mRNA, titanium dioxide results in decreased expression of GRIN1 protein CTD PMID:25411160 tocopherol increases expression ISO RGD:10685 6480464 Tocopherols results in increased expression of GRIN1 mRNA CTD PMID:17654050 toluene increases expression ISO RGD:10685 6480464 Toluene results in increased expression of GRIN1 mRNA CTD PMID:20804784 tributylstannane decreases expression EXP 6480464 tributyltin results in decreased expression of GRIN1 mRNA CTD PMID:19591855 trichlopyr decreases expression ISO RGD:10685 6480464 triclopyr results in decreased expression of GRIN1 mRNA CTD PMID:21318024 trichlopyr multiple interactions ISO RGD:10685 6480464 arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide inhibits the reaction [triclopyr results in decreased expression of GRIN1 mRNA] CTD PMID:21318024 urethane multiple interactions ISO RGD:731784 6480464 Urethane inhibits the reaction [Excitatory Amino Acid Agonists binds to and results in increased activity of [GRIN1 protein binds to GRIN2A protein]] CTD PMID:11812690 valproic acid decreases expression EXP 6480464 Valproic Acid results in decreased expression of GRIN1 mRNA CTD PMID:19651682 vinclozolin multiple interactions EXP 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of GRIN1 mRNA CTD PMID:25607892
Biological Process adult locomotory behavior ISO RGD:10685 1624291 MGI:MGI:1928280 more ... RGD MGI:MGI:1343743 more ... adult locomotory behavior IEA UniProtKB:P35438 , ensembl:ENSMUSP000000283351600115 GO_REF:0000107 Ensembl GO_REF:0000107 associative learning ISO RGD:10685 1624291 MGI:MGI:1928279 more ... RGD MGI:MGI:2182479 more ... calcium ion homeostasis ISO RGD:10685 1624291 (MGI:MGI:65181, PMID:7907365) RGD MGI:MGI:65181 , PMID:7907365 calcium ion transmembrane import into cytosol ISO RGD:731784 1624291 (PMID:26875626) RGD PMID:26875626 calcium ion transmembrane import into cytosol IEA UniProtKB:Q05586 , ensembl:ENSP000003606081600115 GO_REF:0000107 Ensembl GO_REF:0000107 calcium ion transport ISO RGD:10685 1624291 MGI:MGI:2178083 more ... RGD MGI:MGI:3622400 more ... calcium-mediated signaling IEA GO:0022849 1600115 GO_REF:0000108 GOC GO_REF:0000108 cation transport ISO RGD:10685 1624291 MGI:MGI:95821 (MGI:MGI:69304 , PMID:7531804) RGD MGI:MGI:69304 , PMID:7531804 cation transport ISO RGD:731784 1624291 (PMID:7685113) RGD PMID:7685113 cellular calcium ion homeostasis ISO RGD:10685 1624291 MGI:MGI:1928327 (MGI:MGI:1928326 , PMID:8060614) RGD MGI:MGI:1928326 , PMID:8060614 cellular response to amyloid-beta NOT ISO RGD:731784 1624291 UniProtKB:Q12879 (PMID:21883149) RGD PMID:21883149 cellular response to manganese ion IEP 2325970 RGD cerebral cortex development ISO RGD:10685 1624291 MGI:MGI:1928279 more ... RGD MGI:MGI:1888650 more ... cerebral cortex development IEA UniProtKB:P35438 , ensembl:ENSMUSP000000283351600115 GO_REF:0000107 Ensembl GO_REF:0000107 chemical synaptic transmission IBA FB:FBgn0010399 more ... 13792537 PMID:21873635 GO_Central conditioned taste aversion ISO RGD:10685 1624291 MGI:MGI:1928279 more ... RGD MGI:MGI:3589959 , PMID:16101757 conditioned taste aversion IEA UniProtKB:P35438 , ensembl:ENSMUSP000000283351600115 GO_REF:0000107 Ensembl GO_REF:0000107 excitatory postsynaptic potential ISO RGD:10685 1624291 MGI:MGI:1928279 more ... RGD MGI:MGI:2682163 more ... excitatory postsynaptic potential IEA UniProtKB:P35438 , ensembl:ENSMUSP000000283351600115 GO_REF:0000107 Ensembl GO_REF:0000107 ionotropic glutamate receptor signaling pathway IDA 1642190 RGD ionotropic glutamate receptor signaling pathway ISO RGD:731784 1624291 (PMID:28228639) RGD PMID:28228639 ionotropic glutamate receptor signaling pathway IBA FB:FBgn0010399 more ... 13792537 PMID:21873635 GO_Central ionotropic glutamate receptor signaling pathway IEA UniProtKB:Q05586 , ensembl:ENSP000003606081600115 GO_REF:0000107 Ensembl GO_REF:0000107 ionotropic glutamate receptor signaling pathway IEA UniProtKB:P35438 , ensembl:ENSMUSP000000283351600115 GO_REF:0000107 Ensembl GO_REF:0000107 ionotropic glutamate receptor signaling pathway ISO RGD:10685 1624291 (MGI:MGI:3604036, PMID:16025111) RGD MGI:MGI:3604036 , PMID:16025111 learning ISO RGD:10685 1624291 MGI:MGI:3692441 (MGI:MGI:3691363 , PMID:17015831) RGD MGI:MGI:3691363 , PMID:17015831 learning or memory TAS 727495 RGD learning or memory ISO RGD:10685 1624291 MGI:MGI:1928279 more ... RGD MGI:MGI:3664028 , PMID:17004940 long-term memory ISO RGD:10685 1624291 MGI:MGI:1928279 more ... RGD MGI:MGI:3036924 , PMID:15003177 long-term memory IEA UniProtKB:P35438 , ensembl:ENSMUSP000000283351600115 GO_REF:0000107 Ensembl GO_REF:0000107 male mating behavior ISO RGD:10685 1624291 MGI:MGI:1928280 (MGI:MGI:1343743 , PMID:10481908) RGD MGI:MGI:1343743 , PMID:10481908 male mating behavior IEA UniProtKB:P35438 , ensembl:ENSMUSP000000283351600115 GO_REF:0000107 Ensembl GO_REF:0000107 memory ISO RGD:10685 1624291 MGI:MGI:1928279 more ... RGD MGI:MGI:1353841 more ... negative regulation of neuron apoptotic process ISO RGD:10685 1624291 MGI:MGI:1928270 more ... RGD MGI:MGI:3695621 , PMID:17077143 negative regulation of neuron apoptotic process IEA UniProtKB:P35438 , ensembl:ENSMUSP000000283351600115 GO_REF:0000107 Ensembl GO_REF:0000107 neuromuscular process ISO RGD:10685 1624291 MGI:MGI:1928270 (MGI:MGI:65431 , PMID:8313466) RGD MGI:MGI:65431 , PMID:8313466 olfactory learning ISO RGD:10685 1624291 MGI:MGI:1928279 more ... RGD MGI:MGI:1353841 more ... olfactory learning IEA UniProtKB:P35438 , ensembl:ENSMUSP000000283351600115 GO_REF:0000107 Ensembl GO_REF:0000107 pons maturation ISO RGD:10685 1624291 MGI:MGI:1928270 (MGI:MGI:65431 , PMID:8313466) RGD MGI:MGI:65431 , PMID:8313466 pons maturation IEA UniProtKB:P35438 , ensembl:ENSMUSP000000283351600115 GO_REF:0000107 Ensembl GO_REF:0000107 positive regulation of apoptotic process ISO RGD:10685 1624291 MGI:MGI:1096575 more ... RGD MGI:MGI:3757796 , PMID:17803966 positive regulation of apoptotic process IEA UniProtKB:P35438 , ensembl:ENSMUSP000000283351600115 GO_REF:0000107 Ensembl GO_REF:0000107 positive regulation of calcium ion transport into cytosol IGI ComplexPortal:CPX-1134 12910994 PMID:17308309 ARUK-UCL positive regulation of cell death IDA 2325881 RGD positive regulation of cysteine-type endopeptidase activity IGI UniProtKB:Q00960 13506268 PMID:17526495 ARUK-UCL positive regulation of dendritic spine maintenance IGI ComplexPortal:CPX-1120, UniProtKB:P05067:VAR_000023 12793018 PMID:17360908 ARUK-UCL positive regulation of excitatory postsynaptic potential IDA 8554754 PMID:12930820 BHF-UCL positive regulation of reactive oxygen species biosynthetic process IGI ComplexPortal:CPX-1134 12910994 PMID:17308309 ARUK-UCL positive regulation of Schwann cell migration IMP 13792690 RGD positive regulation of transcription by RNA polymerase II ISO RGD:10685 1624291 (MGI:MGI:65181, PMID:7907365) RGD MGI:MGI:65181 , PMID:7907365 positive regulation of transcription by RNA polymerase II IEA UniProtKB:P35438 , ensembl:ENSMUSP000000283351600115 GO_REF:0000107 Ensembl GO_REF:0000107 prepulse inhibition ISO RGD:10685 1624291 MGI:MGI:1928280 (MGI:MGI:3051067 , PMID:15265649) RGD MGI:MGI:3051067 , PMID:15265649 prepulse inhibition IEA UniProtKB:P35438 , ensembl:ENSMUSP000000283351600115 GO_REF:0000107 Ensembl GO_REF:0000107 propylene metabolic process ISO RGD:10685 1624291 (MGI:MGI:5320264, PMID:21795692) RGD MGI:MGI:5320264 , PMID:21795692 propylene metabolic process IEA UniProtKB:P35438 , ensembl:ENSMUSP000000283351600115 GO_REF:0000107 Ensembl GO_REF:0000107 protein heterotetramerization IDA 13432263 PMID:24876489 UniProt protein localization to postsynaptic membrane ISO RGD:10685 1624291 MGI:MGI:1928279 more ... RGD MGI:MGI:2661373 , PMID:12676993 protein localization to postsynaptic membrane IEA UniProtKB:P35438 , ensembl:ENSMUSP000000283351600115 GO_REF:0000107 Ensembl GO_REF:0000107 protein-containing complex assembly IDA 7241301 homodimerization RGD regulation of axonogenesis ISO RGD:10685 1624291 MGI:MGI:1928270 (MGI:MGI:3579211 , PMID:15745956) RGD MGI:MGI:3579211 , PMID:15745956 regulation of axonogenesis IEA UniProtKB:P35438 , ensembl:ENSMUSP000000283351600115 GO_REF:0000107 Ensembl GO_REF:0000107 regulation of cell communication ISO RGD:10685 1624291 MGI:MGI:1928270 (MGI:MGI:3610881 , PMID:16299502) RGD MGI:MGI:3610881 , PMID:16299502 regulation of dendrite morphogenesis ISO RGD:10685 1624291 MGI:MGI:1928270 (MGI:MGI:3579211 , PMID:15745956) RGD MGI:MGI:3579211 , PMID:15745956 regulation of dendrite morphogenesis IEA UniProtKB:P35438 , ensembl:ENSMUSP000000283351600115 GO_REF:0000107 Ensembl GO_REF:0000107 regulation of long-term neuronal synaptic plasticity ISO RGD:10685 1624291 MGI:MGI:1928283 more ... RGD MGI:MGI:1858680 more ... regulation of long-term neuronal synaptic plasticity IEA UniProtKB:P35438 , ensembl:ENSMUSP000000283351600115 GO_REF:0000107 Ensembl GO_REF:0000107 regulation of membrane potential ISO RGD:731784 1624291 (PMID:17047094), (PMID:7679115), (PMID:7685113) RGD PMID:17047094 more ... regulation of membrane potential IBA FB:FBgn0010399 more ... 13792537 PMID:21873635 GO_Central regulation of membrane potential ISO RGD:10685 1624291 MGI:MGI:1928279 more ... RGD MGI:MGI:1928326 more ... regulation of neuron apoptotic process ISO RGD:10685 1624291 MGI:MGI:1928279 more ... RGD MGI:MGI:1344923 more ... regulation of neuronal synaptic plasticity ISO RGD:10685 1624291 MGI:MGI:2178083 more ... RGD MGI:MGI:3622400 , PMID:15576450 regulation of presynaptic membrane potential IEA GO:0099507 1600115 GO_REF:0000108 GOC GO_REF:0000108 regulation of respiratory gaseous exchange IEA UniProtKB:P35438 , ensembl:ENSMUSP000000283351600115 GO_REF:0000107 Ensembl GO_REF:0000107 regulation of respiratory gaseous exchange ISO RGD:10685 1624291 MGI:MGI:1928270 (MGI:MGI:2137201 more ... RGD MGI:MGI:2137201 more ... regulation of synapse assembly ISO RGD:10685 1624291 MGI:MGI:2655232 more ... RGD MGI:MGI:2654367 , PMID:12657691 regulation of synapse assembly IEA UniProtKB:P35438 , ensembl:ENSMUSP000000283351600115 GO_REF:0000107 Ensembl GO_REF:0000107 regulation of synaptic plasticity ISO RGD:10685 1624291 MGI:MGI:1928279 more ... RGD MGI:MGI:3036924 more ... response to amine IEP 2325941 ketamine RGD response to amphetamine ISO RGD:10685 1624291 MGI:MGI:1928280 more ... RGD MGI:MGI:3629445 more ... response to amphetamine IEA UniProtKB:P35438 , ensembl:ENSMUSP000000283351600115 GO_REF:0000107 Ensembl GO_REF:0000107 response to calcium ion IEP 2325954 RGD response to ethanol ISO RGD:731784 1624291 (PMID:18445116) RGD PMID:18445116 response to ethanol IEA UniProtKB:Q05586 , ensembl:ENSP000003606081600115 GO_REF:0000107 Ensembl GO_REF:0000107 response to fungicide IEP 2325972 tributyltin RGD response to glycine ISO RGD:731784 1624291 (PMID:28105280) RGD PMID:28105280 response to glycine IEA UniProtKB:Q05586 , ensembl:ENSP000003606081600115 GO_REF:0000107 Ensembl GO_REF:0000107 response to morphine ISO RGD:10685 1624291 MGI:MGI:1928270 (MGI:MGI:3797147 , PMID:18423864) RGD MGI:MGI:3797147 , PMID:18423864 response to morphine IEA UniProtKB:P35438 , ensembl:ENSMUSP000000283351600115 GO_REF:0000107 Ensembl GO_REF:0000107 response to organic cyclic compound IEP 2326006 ouabain RGD rhythmic process IDA 1642190 RGD sensory perception of pain ISO RGD:10685 1624291 MGI:MGI:1928279 (MGI:MGI:2667460 , PMID:12832526) RGD MGI:MGI:2667460 , PMID:12832526 sensory perception of pain IEA UniProtKB:P35438 , ensembl:ENSMUSP000000283351600115 GO_REF:0000107 Ensembl GO_REF:0000107 social behavior ISO RGD:10685 1624291 MGI:MGI:1928280 (MGI:MGI:1343743 , PMID:10481908) RGD MGI:MGI:1343743 , PMID:10481908 social behavior IEA UniProtKB:P35438 , ensembl:ENSMUSP000000283351600115 GO_REF:0000107 Ensembl GO_REF:0000107 startle response ISO RGD:10685 1624291 MGI:MGI:1928283 more ... RGD MGI:MGI:1858680 , PMID:10818139 suckling behavior ISO RGD:10685 1624291 MGI:MGI:1928270 (MGI:MGI:2137201 more ... RGD MGI:MGI:2137201 more ... suckling behavior IEA UniProtKB:P35438 , ensembl:ENSMUSP000000283351600115 GO_REF:0000107 Ensembl GO_REF:0000107 synaptic transmission, glutamatergic ISO RGD:10685 1624291 MGI:MGI:1928270 more ... RGD MGI:MGI:1888650 more ... synaptic transmission, glutamatergic IEA UniProtKB:P35438 , ensembl:ENSMUSP000000283351600115 GO_REF:0000107 Ensembl GO_REF:0000107 visual learning ISO RGD:10685 1624291 MGI:MGI:1928279 more ... RGD MGI:MGI:1858680 more ... visual learning IEA UniProtKB:P35438 , ensembl:ENSMUSP000000283351600115 GO_REF:0000107 Ensembl GO_REF:0000107 Cellular Component basolateral plasma membrane ISO RGD:9033659 1624291 RGD RGD:11556222 cell surface IDA 13506268 PMID:17526495 ARUK-UCL cell surface IEA UniProtKB:P35438 , ensembl:ENSMUSP000000283351600115 GO_REF:0000107 Ensembl GO_REF:0000107 cell surface ISO RGD:10685 1624291 (MGI:MGI:3765383, PMID:17229826) RGD MGI:MGI:3765383 , PMID:17229826 cytoplasm ISO RGD:10685 1624291 (MGI:MGI:2445233, PMID:12414093) RGD MGI:MGI:2445233 , PMID:12414093 cytoplasm IDA 13506268 PMID:17526495 ARUK-UCL dendrite ISO RGD:731784 1624291 (PMID:10749211) RGD PMID:10749211 dendrite ISO RGD:10685 1624291 (MGI:MGI:3765383 more ... RGD MGI:MGI:3765383 more ... dendrite membrane IDA 8553937 PMID:15620359 BHF-UCL dendritic branch IDA 631929 RGD dendritic spine IDA 1642304 RGD dendritic spine IEA UniProtKB:P35438 , ensembl:ENSMUSP000000283351600115 GO_REF:0000107 Ensembl GO_REF:0000107 dendritic spine ISO RGD:10685 1624291 (MGI:MGI:3526504, PMID:15663482) RGD MGI:MGI:3526504 , PMID:15663482 endoplasmic reticulum ISO RGD:10685 1624291 (MGI:MGI:3654399, PMID:16814779) RGD MGI:MGI:3654399 , PMID:16814779 endoplasmic reticulum IEA UniProtKB:P35438 , ensembl:ENSMUSP000000283351600115 GO_REF:0000107 Ensembl GO_REF:0000107 excitatory synapse IDA 8554379 PMID:19730411 BHF-UCL glutamatergic synapse IEA UniProtKB:P35438 , ensembl:ENSMUSP000000283351600115 GO_REF:0000107 Ensembl GO_REF:0000107 glutamatergic synapse IMP 13792531 PMID:12160751 SynGO glutamatergic synapse IDA 13792531 PMID:12160751 SynGO glutamatergic synapse ISO RGD:10685 1624291 (MGI:MGI:4358803, PMID:19726645) RGD MGI:MGI:4358803 , PMID:19726645 hippocampal mossy fiber to CA3 synapse IDA 13702288 PMID:23159309 SynGO integral component of plasma membrane ISO RGD:731784 1624291 (PMID:26875626), (PMID:26919761), (PMID:28105280), (PMID:7685113) RGD PMID:26875626 more ... integral component of plasma membrane IDA 13432313 PMID:28384476 UniProt integral component of plasma membrane IDA 13432263 PMID:24876489 UniProt integral component of plasma membrane IDA 13432252 PMID:18177891 UniProt integral component of postsynaptic density membrane IDA 13702288 PMID:23159309 SynGO integral component of postsynaptic density membrane ISO RGD:10685 1624291 (MGI:MGI:4358803, PMID:19726645) RGD MGI:MGI:4358803 , PMID:19726645 integral component of postsynaptic density membrane IEA UniProtKB:P35438 , ensembl:ENSMUSP000000283351600115 GO_REF:0000107 Ensembl GO_REF:0000107 integral component of presynaptic membrane IDA 2325961 PMID:19666514 SynGO membrane ISO RGD:10685 1624291 (MGI:MGI:1859430 more ... RGD MGI:MGI:1859430 more ... neuron projection IBA MGI:MGI:95819 more ... 13792537 PMID:21873635 GO_Central neuronal cell body ISO RGD:9033659 1624291 RGD RGD:11556222 neuronal cell body IDA 631929 RGD NMDA selective glutamate receptor complex IDA 1642190 ; 1642380 ; 7241301 RGD NMDA selective glutamate receptor complex IBA FB:FBgn0010399 more ... 13792537 PMID:21873635 GO_Central NMDA selective glutamate receptor complex IDA 13432252 PMID:18177891 UniProt NMDA selective glutamate receptor complex IDA 13432313 PMID:28384476 UniProt NMDA selective glutamate receptor complex IDA 13432263 PMID:24876489 UniProt NMDA selective glutamate receptor complex IEA UniProtKB:Q05586 , ensembl:ENSP000003606081600115 GO_REF:0000107 Ensembl GO_REF:0000107 NMDA selective glutamate receptor complex IEA UniProtKB:P35438 , ensembl:ENSMUSP000000283351600115 GO_REF:0000107 Ensembl GO_REF:0000107 NMDA selective glutamate receptor complex ISO RGD:731784 1624291 (PMID:10480938), (PMID:17047094), (PMID:26875626), (PMID:26919761), (PMID:28105280), (PMID:7679115) RGD PMID:10480938 more ... NMDA selective glutamate receptor complex ISO RGD:10685 1624291 PR:P35436 more ... RGD MGI:MGI:85255 , PMID:9003035 NMDA selective glutamate receptor complex TAS 727495 RGD parallel fiber to Purkinje cell synapse IDA 2325961 PMID:19666514 SynGO plasma membrane TAS 1600115 Reactome:R-RNO-9614228 Reactome Reactome:R-RNO-9614228 plasma membrane TAS 1600115 Reactome:R-RNO-9618659 Reactome Reactome:R-RNO-9618659 plasma membrane TAS 1600115 Reactome:R-RNO-9617436 Reactome Reactome:R-RNO-9617436 plasma membrane TAS 1600115 Reactome:R-RNO-9617322 Reactome Reactome:R-RNO-9617322 plasma membrane TAS 1600115 Reactome:R-RNO-9612145 Reactome Reactome:R-RNO-9612145 plasma membrane ISO RGD:731784 1624291 (PMID:28228639) RGD PMID:28228639 plasma membrane IBA FB:FBgn0004620 more ... 13792537 PMID:21873635 GO_Central plasma membrane TAS 1600115 Reactome:R-RNO-9614351 Reactome Reactome:R-RNO-9614351 plasma membrane TAS 1600115 Reactome:R-RNO-9614350 Reactome Reactome:R-RNO-9614350 postsynaptic density IDA 1642304 ; 5508726 RGD postsynaptic density ISO RGD:10685 1624291 (MGI:MGI:3054180 more ... RGD MGI:MGI:3054180 more ... postsynaptic density membrane ISO RGD:10685 1624291 (MGI:MGI:4358803, PMID:19726645) RGD MGI:MGI:4358803 , PMID:19726645 postsynaptic membrane ISO RGD:10685 1624291 (MGI:MGI:2155573 more ... RGD MGI:MGI:2155573 more ... synapse IDA 8553420 PMID:15681343 MGI synapse IBA FB:FBgn0010399 more ... 13792537 PMID:21873635 GO_Central synapse IDA 13792692 RGD synapse ISO RGD:10685 1624291 (MGI:MGI:2682163 more ... RGD MGI:MGI:2682163 more ... synapse IDA 8661623 PMID:15978582 MGI synapse IDA 8554175 PMID:17003121 MGI synaptic cleft IDA 1642304 RGD synaptic membrane IPI ComplexPortal:CPX-1134 12910994 PMID:17308309 ARUK-UCL synaptic vesicle ISO RGD:10685 1624291 (MGI:MGI:1859430, PMID:10846156) RGD MGI:MGI:1859430 , PMID:10846156 synaptic vesicle IEA UniProtKB:P35438 , ensembl:ENSMUSP000000283351600115 GO_REF:0000107 Ensembl GO_REF:0000107 synaptic vesicle membrane ISO RGD:10685 1624291 (MGI:MGI:6150569, PMID:29490264) RGD MGI:MGI:6150569 , PMID:29490264 terminal bouton IDA 2325961 RGD Molecular Function amyloid-beta binding IDA 12910994 PMID:17308309 ARUK-UCL calcium channel activity contributes_to ISO RGD:731784 1624291 (PMID:7685113) RGD PMID:7685113 calcium channel activity ISO RGD:10685 1624291 MGI:MGI:95820 (MGI:MGI:50809 more ... RGD MGI:MGI:50809 more ... calcium ion binding ISO RGD:10685 1624291 (MGI:MGI:3526504, PMID:15663482) RGD MGI:MGI:3526504 , PMID:15663482 calcium ion binding IEA UniProtKB:P35438 , ensembl:ENSMUSP000000283351600115 GO_REF:0000107 Ensembl GO_REF:0000107 calmodulin binding ISO RGD:10685 1624291 (MGI:MGI:3526504, PMID:15663482) RGD MGI:MGI:3526504 , PMID:15663482 calmodulin binding IEA UniProtKB:P35438 , ensembl:ENSMUSP000000283351600115 GO_REF:0000107 Ensembl GO_REF:0000107 cation channel activity ISO RGD:10685 1624291 MGI:MGI:95821 (MGI:MGI:69304 , PMID:7531804) RGD MGI:MGI:69304 , PMID:7531804 enzyme binding IPI RGD:620556 2302311 RGD glutamate binding ISO RGD:731784 1624291 (PMID:7685113) RGD PMID:7685113 glutamate binding IEA UniProtKB:Q05586 , ensembl:ENSP000003606081600115 GO_REF:0000107 Ensembl GO_REF:0000107 glutamate binding IDA 8553919 PMID:8011339 UniProt glutamate receptor binding IPI RGD:2737 , RGD:2738 2326007 RGD glutamate-gated calcium ion channel activity ISO RGD:731784 1624291 (PMID:26875626) RGD PMID:26875626 glutamate-gated calcium ion channel activity IEA UniProtKB:Q05586 , ensembl:ENSP000003606081600115 GO_REF:0000107 Ensembl GO_REF:0000107 glycine binding IDA 7241434 RGD glycine binding IDA 13432263 PMID:24876489 UniProt glycine binding IEA UniProtKB:Q05586 , ensembl:ENSP000003606081600115 GO_REF:0000107 Ensembl GO_REF:0000107 glycine binding IEA UniProtKB:P35438 , ensembl:ENSMUSP000000283351600115 GO_REF:0000107 Ensembl GO_REF:0000107 glycine binding ISO RGD:10685 1624291 (MGI:MGI:3687923, PMID:12586454) RGD MGI:MGI:3687923 , PMID:12586454 glycine binding ISO RGD:731784 1624291 (PMID:17047094), (PMID:28105280), (PMID:7685113) RGD PMID:17047094 more ... glycine binding IDA 8553919 PMID:8011339 UniProt ionotropic glutamate receptor activity IDA 1642190 RGD ionotropic glutamate receptor activity TAS 727495 RGD ligand-gated ion channel activity IBA FB:FBgn0004619 more ... 13792537 PMID:21873635 GO_Central ligand-gated ion channel activity involved in regulation of presynaptic membrane potential IDA 2325961 PMID:19666514 SynGO ligand-gated ion channel activity involved in regulation of presynaptic membrane potential IMP 2325961 PMID:19666514 SynGO ligand-gated ion channel activity involved in regulation of presynaptic membrane potential EXP 2325961 PMID:19666514 SynGO neurotransmitter binding IDA 1642190 RGD NMDA glutamate receptor activity IDA 1642190 ; 7241434 RGD NMDA glutamate receptor activity contributes_to IBA FB:FBgn0010399 more ... 13792537 PMID:21873635 GO_Central NMDA glutamate receptor activity ISO RGD:731784 1624291 (PMID:26919761), (PMID:28105280), (PMID:28228639) RGD PMID:26919761 more ... NMDA glutamate receptor activity IDA 13432313 PMID:28384476 UniProt NMDA glutamate receptor activity IDA 13432263 PMID:24876489 UniProt NMDA glutamate receptor activity IDA 13432252 PMID:18177891 UniProt NMDA glutamate receptor activity IEA UniProtKB:Q05586 , ensembl:ENSP000003606081600115 GO_REF:0000107 Ensembl GO_REF:0000107 NMDA glutamate receptor activity IEA UniProtKB:P35438 , ensembl:ENSMUSP000000283351600115 GO_REF:0000107 Ensembl GO_REF:0000107 NMDA glutamate receptor activity contributes_to ISO RGD:731784 1624291 (PMID:7679115), (PMID:7685113) RGD PMID:7679115 , PMID:7685113 NMDA glutamate receptor activity IGI MGI:MGI:95820 8553485 PMID:7929101 MGI NMDA glutamate receptor activity ISO RGD:10685 1624291 MGI:MGI:1928270 more ... RGD MGI:MGI:1888650 more ... NMDA glutamate receptor activity IMP 1642380 RGD NMDA glutamate receptor activity TAS 727495 RGD phosphatase binding IDA 12802359 Pten RGD protein binding IPI RGD:70993 2326007 RGD protein binding ISO RGD:10685 1624291 MGI:MGI:104684 more ... RGD MGI:MGI:1195436 more ... protein binding IPI UniProtKB:Q00960 13432283 PMID:21677647 IntAct protein binding IPI UniProtKB:Q00960 13432235 PMID:27135925 IntAct protein binding IPI UniProtKB:Q00960 13432263 PMID:24876489 IntAct protein binding IPI UniProtKB:Q00960 13432354 PMID:19243221 IntAct protein binding IPI UniProtKB:Q00960 8553636 PMID:8780649 IntAct protein binding IPI UniProtKB:P31016 8554569 PMID:23567299 IntAct protein binding IPI UniProtKB:P31016 4144068 PMID:20628354 IntAct protein binding IPI UniProtKB:Q80TG9 8554054 PMID:16495444 IntAct protein binding IPI UniProtKB:Q460M5 8554054 PMID:16495444 IntAct protein binding IPI UniProtKB:Q9JJ40 8554049 PMID:16054660 IntAct protein binding IPI UniProtKB:P31016 8554049 PMID:16054660 IntAct protein binding ISO RGD:731784 1624291 UniProtKB:Q13224 more ... RGD PMID:11937501 more ... protein binding IPI UniProtKB:P0C6T3 13702279 PMID:27458189 UniProt protein binding IPI UniProtKB:P0C5W1 8553944 PMID:17658481 UniProt protein binding IPI RGD:1308864 9685716 RGD protein binding IPI RGD:620833 631929 RGD protein binding IPI RGD:70991 2326007 RGD protein-containing complex binding IDA 7241301 heterotetramerization RGD protein-containing complex binding IPI ComplexPortal:CPX-1134 12910994 PMID:17308309 ARUK-UCL protein-containing complex binding IDA 7241533 heterodimerization RGD signaling receptor activity IBA FB:FBgn0004619 more ... 13792537 PMID:21873635 GO_Central signaling receptor binding ISO RGD:10685 1624291 PR:P54763 (MGI:MGI:2155580, PMID:11754835) RGD MGI:MGI:2155580 , PMID:11754835 signaling receptor binding IEA UniProtKB:P35438 , ensembl:ENSMUSP000000283351600115 GO_REF:0000107 Ensembl GO_REF:0000107 signaling receptor binding IPI RGD:2518 1581396 RGD transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential ISO RGD:10685 1624291 (MGI:MGI:3807355, PMID:18728179) RGD MGI:MGI:3807355 , PMID:18728179 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential IMP 13792531 PMID:12160751 SynGO transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential IDA 13792531 PMID:12160751 SynGO transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential IEA UniProtKB:P35438 , ensembl:ENSMUSP000000283351600115 GO_REF:0000107 Ensembl GO_REF:0000107 voltage-gated cation channel activity IMP 1642380 RGD
Gene-Chemical Interaction Annotations
