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Gene: Tubb3 (tubulin, beta 3 class III) Rattus norvegicus
Symbol: Tubb3
Name: tubulin, beta 3 class III
Description: Exhibits peptide binding activity. Involved in mitotic cell cycle and neuron differentiation. Localizes to the axon. Human ortholog(s) of this gene implicated in complex cortical dysplasia with other brain malformations 1 and congenital fibrosis of the extraocular muscles. Orthologous to human TUBB3 (tubulin beta 3 class III); PARTICIPATES IN phagocytosis pathway; INTERACTS WITH (RS)-amphetamine; 17alpha-ethynylestradiol; 2,4,6-trinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: neuron-specific class III beta-tubulin; tubulin beta-3 chain; tubulin, beta 3
Homo sapiens (human) : TUBB3 (tubulin beta 3 class III)  HGNC  Alliance
Mus musculus (house mouse) : Tubb3 (tubulin, beta 3 class III)  MGI  Alliance
Canis lupus familiaris (dog) : TUBB3 (tubulin beta 3 class III)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tubb3 (tubulin beta 3 class III)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01956,220,759 - 56,229,813 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01966,931,880 - 66,940,930 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41953,742,652 - 53,751,706 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14155,058,769 - 155,059,105 (+)NCBI
Celera1950,689,724 - 50,698,713 (+)NCBICelera
Cytogenetic Map19q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Tubb3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 628595
Created: 2003-02-27
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.