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Gene: Tubb3 (tubulin, beta 3 class III) Mus musculus
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Symbol: Tubb3
Name: tubulin, beta 3 class III
Description: Exhibits netrin receptor binding activity. Involved in axon guidance and netrin-activated signaling pathway. Localizes to several cellular components, including the filopodium; growth cone; and lamellipodium. Used to study congenital fibrosis of the extraocular muscles. Human ortholog(s) of this gene implicated in complex cortical dysplasia with other brain malformations 1 and congenital fibrosis of the extraocular muscles. Is expressed in several structures, including alimentary system; cardiovascular system; future brain; nervous system; and sensory organ. Orthologous to human TUBB3 (tubulin beta 3 class III); INTERACTS WITH (S)-amphetamine; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 3200002H15Rik; betaIII-tubulin; M(beta)3; M(beta)6; tubulin beta-3 chain
Orthologs:
Homo sapiens (human) : TUBB3 (tubulin beta 3 class III)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tubb3 (tubulin, beta 3 class III)  Alliance
Canis lupus familiaris (dog) : TUBB3 (tubulin beta 3 class III)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tubb3 (tubulin beta 3 class III)
Heterocephalus glaber (naked mole-rat) : Tubb3 (tubulin beta 3 class III)
more info ...
Related Pseudogenes: Tubb3-ps1  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl8123,411,424 - 123,422,015 (+)Ensembl
GRCm388123,411,553 - 123,422,015 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv378125,935,464 - 125,945,910 (+)NCBIGRCm37mm9NCBIm37
MGSCv368126,297,654 - 126,308,100 (+)NCBImm8
Celera8127,654,088 - 127,664,534 (+)NCBICelera
Cytogenetic Map8E1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Tubb3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1550181
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-02-11
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.