Gene: Slc18a1 (solute carrier family 18 member A1) Rattus norvegicus
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Symbol: Slc18a1
Name: solute carrier family 18 member A1
Description: ENCODES a protein that exhibits enzyme binding; serotonin:sodium symporter activity; INVOLVED IN cellular response to lithium ion; negative regulation of serotonin uptake; positive regulation of dopamine secretion; PARTICIPATES IN Parkinson's disease pathway; ASSOCIATED WITH bipolar disorder (ortholog); schizophrenia (ortholog); von Hippel-Lindau disease (ortholog); FOUND IN cytoplasm; synapse (ortholog); INTERACTS WITH 17beta-estradiol; 6-propyl-2-thiouracil; ammonium chloride
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CGAT; chromaffin granule amine transporter; LOC684870; similar to solute carrier family 18 (vesicular monoamine), member 1; solute carrier family 18 (vesicular monoamine transporter), member 1; solute carrier family 18 (vesicular monoamine), member 1; solute carrier family 18 member 1; solute carrier family 18, member 1; Solute carrier family18 (vesicular monoamine) member 1 (chromaffin granule amine transporter); VAT1; vesicular amine transporter 1; vesicular monoamine transporter 1; VMAT-1; VMAT1
Orthologs:
Homo sapiens (human) : SLC18A1 (solute carrier family 18 member A1)  HGNC  Alliance
Mus musculus (house mouse) : Slc18a1 (solute carrier family 18 (vesicular monoamine), member 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc18a1 (solute carrier family 18 member A1)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC18A1 (solute carrier family 18 member A1)
Canis lupus familiaris (dog) : SLC18A1 (solute carrier family 18 member A1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc18a1 (solute carrier family 18 member A1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01622,358,646 - 22,395,183 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01622,256,523 - 22,289,704 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41622,356,304 - 22,389,827 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11622,356,297 - 22,389,825 (+)NCBI
Celera1620,629,165 - 20,846,643 (+)NCBICelera
Cytogenetic Map16p14NCBI
RH 3.4 Map16253.67RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model

Annotation    (Toggle Annotation Detail/Summary View)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
  
More on Slc18a1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3693
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2018-10-09
Status: ACTIVE



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