Slc18a1 (solute carrier family 18 member A1) - Rat Genome Database
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Gene: Slc18a1 (solute carrier family 18 member A1) Ictidomys tridecemlineatus
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Symbol: Slc18a1
Name: solute carrier family 18 member A1
RGD ID: 12444624
Description: ENCODES a protein that exhibits enzyme binding (ortholog); serotonin:sodium symporter activity (ortholog); INVOLVED IN cellular response to lithium ion (ortholog); negative regulation of serotonin uptake (ortholog); positive regulation of dopamine secretion (ortholog); ASSOCIATED WITH bipolar disorder (ortholog); schizophrenia (ortholog); von Hippel-Lindau disease (ortholog); FOUND IN cytoplasm (ortholog); synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: chromaffin granule amine transporter
Orthologs:
Homo sapiens (human) : SLC18A1 (solute carrier family 18 member A1)  HGNC  Alliance
Mus musculus (house mouse) : Slc18a1 (solute carrier family 18 (vesicular monoamine), member 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Slc18a1 (solute carrier family 18 member A1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc18a1 (solute carrier family 18 member A1)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC18A1 (solute carrier family 18 member A1)
Canis lupus familiaris (dog) : SLC18A1 (solute carrier family 18 member A1)
Sus scrofa (pig) : SLC18A1 (solute carrier family 18 member A1)
Chlorocebus sabaeus (African green monkey) : SLC18A1 (solute carrier family 18 member A1)
Heterocephalus glaber (naked mole-rat) : Slc18a1 (solute carrier family 18 member A1)
more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365554,249,821 - 4,271,379 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (ISO)
synapse  (ISO)

Molecular Function

References

Genomics

Comparative Map Data
Slc18a1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365554,249,821 - 4,271,379 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC18A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl820,144,855 - 20,183,206 (-)EnsemblGRCh38hg38GRCh38
GRCh38820,144,855 - 20,183,139 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37820,002,366 - 20,040,717 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36820,046,652 - 20,084,997 (-)NCBINCBI36hg18NCBI36
Build 34820,046,651 - 20,084,997NCBI
Celera818,964,997 - 19,003,346 (-)NCBI
Cytogenetic Map8p21.3NCBI
HuRef818,542,580 - 18,580,897 (-)NCBIHuRef
CHM1_1820,204,176 - 20,242,504 (-)NCBICHM1_1
Slc18a1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39869,490,360 - 69,547,951 (-)NCBI
GRCm38869,037,708 - 69,089,238 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl869,037,711 - 69,089,235 (-)EnsemblGRCm38mm10GRCm38
MGSCv37871,561,607 - 71,613,121 (-)NCBIGRCm37mm9NCBIm37
MGSCv36871,966,697 - 72,018,211 (-)NCBImm8
Celera871,585,811 - 71,639,074 (-)NCBICelera
Cytogenetic Map8B3.3NCBI
cM Map833.88NCBI
Slc18a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01622,358,646 - 22,395,183 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1622,361,998 - 22,395,183 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01622,256,523 - 22,289,704 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41622,356,304 - 22,389,827 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11622,356,297 - 22,389,825 (+)NCBI
Celera1620,629,165 - 20,846,643 (+)NCBICelera
Cytogenetic Map16p14NCBI
RH 3.4 Map16253.67RGD
Slc18a1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540343,821,296 - 43,848,399 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540343,821,978 - 43,848,403 (-)NCBIChiLan1.0ChiLan1.0
SLC18A1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1816,318,744 - 16,353,708 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl816,318,744 - 16,353,708 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0819,369,843 - 19,408,412 (-)NCBIMhudiblu_PPA_v0panPan3
SLC18A1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2536,872,636 - 36,904,056 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12536,859,047 - 36,904,057 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
SLC18A1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl144,243,557 - 4,278,989 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1144,243,553 - 4,279,341 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2144,278,115 - 4,313,822 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SLC18A1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl818,214,701 - 18,249,731 (-)Ensembl
ChlSab1.1818,214,703 - 18,250,025 (-)NCBI
Slc18a1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475815,863,410 - 15,894,958 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_005329287   ⟹   XP_005329344
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0NW_0049365554,249,821 - 4,271,379 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005329288   ⟹   XP_005329345
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0NW_0049365554,249,821 - 4,271,379 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005329344 (Get FASTA)   NCBI Sequence Viewer  
  XP_005329345 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005329345   ⟸   XM_005329288
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_005329344   ⟸   XM_005329287
- Peptide Label: isoform X1
- UniProtKB: I3MHE3 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
MFS


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000011464 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000010294 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000011471 ENTREZGENE, UniProtKB/TrEMBL
InterPro MFS UniProtKB/TrEMBL
  MFS_dom UniProtKB/TrEMBL
  MFS_trans_sf UniProtKB/TrEMBL
  Multidrug-R UniProtKB/TrEMBL
NCBI Gene Slc18a1 ENTREZGENE
Pfam MFS_1 UniProtKB/TrEMBL
PROSITE MFS UniProtKB/TrEMBL
Superfamily-SCOP SSF103473 UniProtKB/TrEMBL
TIGRFAMs 2_A_01_02 UniProtKB/TrEMBL
UniProt I3MHE3 ENTREZGENE, UniProtKB/TrEMBL