Tlr2 (toll-like receptor 2) - Rat Genome Database

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Gene: Tlr2 (toll-like receptor 2) Rattus norvegicus
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Symbol: Tlr2
Name: toll-like receptor 2
RGD ID: 735138
Description: Enables lipopeptide binding activity. Involved in several processes, including central nervous system myelin formation; positive regulation of interleukin-10 production; and response to molecule of bacterial origin. Located in cell body; cell projection; and cell surface. Used to study carotid stenosis; ileitis; keratitis; lung disease (multiple); and renal fibrosis. Biomarker of acute necrotizing pancreatitis; kidney failure; lung disease; pancreatitis; and perinatal necrotizing enterocolitis. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); dermatitis (multiple); gastrointestinal system cancer (multiple); lung disease (multiple); and rhinitis (multiple). Orthologous to human TLR2 (toll like receptor 2); PARTICIPATES IN Toll-like receptor signaling pathway; Chagas disease pathway; Entamoebiasis pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrobenzenesulfonic acid.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: toll-like receptor 2 variant 1; toll-like receptor 2 variant 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22169,200,620 - 169,206,819 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl2169,197,419 - 169,206,630 (-)Ensembl
Rnor_6.02182,840,171 - 182,846,061 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2182,840,727 - 182,846,061 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02202,252,701 - 202,258,962 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42175,607,990 - 175,613,992 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12175,558,096 - 175,564,098 (-)NCBI
Celera2163,202,040 - 163,207,399 (-)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
abdominal obesity-metabolic syndrome 1  (ISO)
acne  (ISO)
acute kidney failure  (ISO)
acute necrotizing pancreatitis  (IEP)
Acute Tubulointerstitial Nephritis  (ISO)
allergic conjunctivitis  (ISO)
allergic rhinitis  (ISO)
alveolar echinococcosis  (ISO)
anogenital venereal wart  (ISO)
anterior uveitis  (ISO)
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis  (ISO)
aspergillosis  (ISO)
asthma  (ISO)
atherosclerosis  (ISO)
atopic dermatitis  (ISO)
atrial fibrillation  (ISO)
Bacterial Eye Infections  (ISO)
Bacterial Keratitis  (ISO)
bacterial pneumonia  (IDA,ISO)
Behcet's disease  (ISO)
Brain Abscess  (ISO)
Brain Injuries  (IEP,ISO)
breast cancer  (ISO)
cardiomyopathy  (ISO)
Cardiotoxicity  (ISO)
carotid artery thrombosis  (ISO)
carotid stenosis  (IDA)
cholangitis  (ISO)
cholestasis  (ISO)
cholesteatoma  (ISO)
cholesteatoma of middle ear  (ISO)
Choroidal Neovascularization  (ISO)
Chronic Hepatitis B  (ISO)
Chronic Pain  (ISO)
Chronic Periodontitis  (ISO)
clonorchiasis  (ISO)
colorectal cancer  (ISO)
Colorectal Neoplasms  (ISO)
congestive heart failure  (ISO)
Cough  (ISO)
cutaneous leishmaniasis  (ISO)
cystic echinococcosis  (ISO)
dermatomyositis  (ISO)
Diabetic Nephropathies  (ISO)
diffuse scleroderma  (ISO)
Drug-Related Side Effects and Adverse Reactions  (ISO)
dry eye syndrome  (ISO)
Dyslipidemias  (IGI)
end stage renal disease  (ISO)
endophthalmitis  (ISO)
Endotoxemia  (IDA)
Eosinophilia  (ISO)
eumycotic mycetoma  (ISO)
Experimental Arthritis  (IEP,ISO)
Experimental Autoimmune Encephalomyelitis  (IEP)
Experimental Autoimmune Neuritis  (IEP)
Experimental Diabetes Mellitus  (IEP,ISO)
Experimental Liver Cirrhosis  (IDA,ISO)
eye disease  (ISO)
Fever  (ISO)
Fungal Eye Infections  (IEP)
gastroesophageal reflux disease  (ISO)
glomerulonephritis  (ISO)
Gram-Positive Bacterial Infections  (ISO)
Hearing Loss  (ISO)
hepatitis B  (ISO)
hepatocellular carcinoma  (ISO)
Herpes Simplex Encephalitis  (IEP,ISO)
herpes simplex virus keratitis  (ISO)
Human Influenza  (ISO)
Hyperalgesia  (IDA,ISO)
Hypoxia-Ischemia, Brain  (ISO)
ileitis  (IMP)
Inflammation  (IDA,ISO)
invasive aspergillosis  (ISO)
keratitis  (IMP,ISO)
keratoconjunctivitis  (ISO)
kidney failure  (IEP)
Kidney Reperfusion Injury  (IDA,ISO)
Kuhnt-Junius degeneration  (ISO)
leprosy  (ISO)
leptospirosis  (ISO)
liver cirrhosis  (ISO)
Liver Reperfusion Injury  (IEP,ISO)
lung disease  (IDA,IEP,ISO)
mastoiditis  (ISO)
membranoproliferative glomerulonephritis  (ISO)
Meningitis, Escherichia Coli  (ISO)
meningococcal meningitis  (ISO)
mite infestation  (ISO)
molluscum contagiosum  (ISO)
myelodysplastic syndrome  (ISO)
Myocardial Reperfusion Injury  (IEP)
Nasal Polyps  (ISO)
non-alcoholic steatohepatitis  (ISO)
obesity  (ISO)
obstructive jaundice  (ISO)
Oral Lichen Planus  (ISO)
otitis media  (ISO)
Otitis Media with Effusion  (ISO)
Pain  (IDA)
pancreatitis  (IEP)
perinatal necrotizing enterocolitis  (IEP)
Plaque, Atherosclerotic  (ISO)
Pneumococcal Meningitis  (ISO)
Pneumococcal Pneumonia  (ISO)
pneumocystosis  (ISO)
pneumonia  (ISO)
prostate cancer  (ISO)
Pseudomonas Aeruginosa Keratitis  (ISO)
psoriasis  (ISO)
pulmonary emphysema  (ISO)
pulmonary fibrosis  (ISO)
pulmonary sarcoidosis  (ISO)
pulmonary tuberculosis  (ISO)
renal fibrosis  (IMP)
Reperfusion Injury  (IEP,ISO)
respiratory syncytial virus infectious disease  (ISO)
rheumatoid arthritis  (ISO)
rhinitis  (ISO)
Rhinosinusitis  (ISO)
sciatic neuropathy  (ISO)
seborrheic dermatitis  (ISO)
Sepsis  (IEP)
severe acute respiratory syndrome  (ISO)
sinusitis  (ISO)
skin papilloma  (ISO)
Staphylococcal Infections  (ISO)
Streptococcal Infections  (ISO)
suppurative otitis media  (ISO)
Transplant Rejection  (IEP,ISO)
tuberculosis  (ISO)
type 1 diabetes mellitus  (ISO)
typhoid fever  (ISO)
urinary bladder cancer  (ISO)
urinary tract infection  (ISO)
visceral leishmaniasis  (ISO)
vitiligo  (ISO)
Wallerian Degeneration  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-pilocarpine  (ISO)
(-)-citrinin  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
1-chloro-2,4,6-trinitrobenzene  (ISO)
15-deoxy-Delta(12,14)-prostaglandin J2  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-mercaptopropanoic acid  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
6alpha-methylprednisolone  (ISO)
acetamide  (EXP)
adapalene  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
Aflatoxin G1  (ISO)
aldehydo-D-glucose  (ISO)
alfacalcidol  (ISO)
all-trans-retinoic acid  (ISO)
all-trans-retinol  (ISO)
alpha-D-galactose  (EXP)
ammonium hexachloroplatinate  (ISO)
amphetamine  (EXP)
antirheumatic drug  (ISO)
arsenous acid  (ISO)
astemizole  (EXP)
atorvastatin calcium  (ISO)
azathioprine  (ISO)
benzene  (ISO)
benzo[a]pyrene  (ISO)
beta-naphthoflavone  (EXP)
bis(2-chloroethyl) sulfide  (ISO)
bisdemethoxycurcumin  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol A diglycidyl ether  (EXP)
bortezomib  (ISO)
butanal  (ISO)
cadmium dichloride  (EXP,ISO)
cannabidiol  (ISO)
carbon atom  (ISO)
carbon nanotube  (ISO)
cefaloridine  (EXP)
cerium trichloride  (ISO)
chitosan  (ISO)
chlorpyrifos  (EXP)
ciguatoxin CTX1B  (ISO)
cisplatin  (ISO)
cobalt atom  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
cortisol  (ISO)
crocidolite asbestos  (ISO)
curcumin  (EXP,ISO)
cyclophosphamide  (ISO)
cyclosporin A  (ISO)
cyproconazole  (ISO)
D-glucose  (ISO)
deoxynivalenol  (ISO)
diarsenic trioxide  (ISO)
dichloroacetic acid  (ISO)
diclofenac  (EXP,ISO)
dioxygen  (EXP,ISO)
disodium selenite  (ISO)
dopamine  (EXP)
doxorubicin  (EXP,ISO)
elemental carbon  (ISO)
endosulfan  (EXP)
epoxiconazole  (ISO)
fenoldopam  (EXP)
ferric oxide  (ISO)
ferulic acid  (ISO)
fipronil  (EXP)
folic acid  (ISO)
fonofos  (ISO)
furan  (EXP)
galactose  (EXP)
genistein  (ISO)
gentamycin  (EXP)
glucose  (ISO)
glutathione  (ISO)
gold atom  (ISO)
gold(0)  (ISO)
graphene oxide  (ISO)
hexamethylene diisocyanate  (ISO)
histamine  (ISO)
hyaluronic acid  (ISO)
hydroxycitronellal  (ISO)
icosanoid  (ISO)
indometacin  (EXP,ISO)
iron(2+) sulfate (anhydrous)  (ISO)
isoeugenol  (ISO)
ivermectin  (ISO)
kaempferol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside  (ISO)
L-ascorbic acid  (ISO)
levamisole  (ISO)
lipophosphoglycan  (ISO)
lipopolysaccharide  (EXP,ISO)
lipoteichoic acid  (ISO)
lycopene  (ISO)
metformin  (ISO)
methamphetamine  (EXP,ISO)
methotrexate  (EXP,ISO)
methylseleninic acid  (ISO)
muramyl dipeptide  (ISO)
N-acetyl-L-cysteine  (ISO)
N-nitrosodiethylamine  (EXP)
nickel atom  (ISO)
nitrites  (ISO)
nitroprusside  (ISO)
o-anisidine  (ISO)
oxaliplatin  (EXP)
ozone  (EXP,ISO)
paclitaxel  (ISO)
paracetamol  (ISO)
paraquat  (ISO)
parathion  (ISO)
pentachlorophenol  (ISO)
pentanal  (ISO)
pentane-2,3-dione  (EXP)
peptidoglycan  (ISO)
phenobarbital  (ISO)
phenytoin  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
pirinixic acid  (ISO)
piroxicam  (ISO)
poly(I:C)  (ISO)
prednisolone  (ISO)
progesterone  (ISO)
propanal  (ISO)
propiconazole  (ISO)
prostaglandin E2  (ISO)
quercetin  (ISO)
reactive oxygen species  (ISO)
resveratrol  (EXP,ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (ISO)
SB 203580  (ISO)
SCH 23390  (EXP)
silicon dioxide  (EXP,ISO)
simvastatin  (ISO)
sodium aurothiomalate  (ISO)
sodium dichromate  (EXP)
sodium dodecyl sulfate  (ISO)
sulfasalazine  (ISO)
sulfur dioxide  (ISO)
sulindac  (EXP)
tacrolimus hydrate  (ISO)
terbufos  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
thymoquinone  (EXP)
titanium atom  (EXP)
titanium dioxide  (EXP,ISO)
topotecan  (EXP)
trans-isoeugenol  (ISO)
tributyrin  (EXP)
trichloroethene  (EXP)
trimellitic anhydride  (ISO)
Tungsten carbide  (ISO)
vinclozolin  (EXP)
vitamin D  (ISO)
vorinostat  (ISO)
zinc oxide  (ISO)
zinc protoporphyrin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
cell activation  (ISO)
cell surface pattern recognition receptor signaling pathway  (ISO)
cellular response to bacterial lipopeptide  (ISO)
cellular response to diacyl bacterial lipopeptide  (ISO)
cellular response to interferon-gamma  (ISO)
cellular response to lipoteichoic acid  (ISO)
cellular response to peptidoglycan  (ISO)
cellular response to triacyl bacterial lipopeptide  (ISO)
central nervous system myelin formation  (IDA)
defense response  (ISO)
defense response to Gram-positive bacterium  (ISO)
defense response to virus  (ISO)
detection of diacyl bacterial lipopeptide  (ISO)
detection of triacyl bacterial lipopeptide  (ISO)
ERK1 and ERK2 cascade  (ISO)
I-kappaB phosphorylation  (ISO)
immune response  (NAS)
inflammatory response  (IBA,IDA)
learning  (ISO)
leukocyte migration  (ISO)
leukotriene metabolic process  (IDA)
microglia development  (ISO)
microglial cell activation  (IDA)
MyD88-dependent toll-like receptor signaling pathway  (ISO)
negative regulation of actin filament polymerization  (ISO)
negative regulation of cell population proliferation  (IDA)
negative regulation of interleukin-12 production  (ISO)
negative regulation of interleukin-17 production  (ISO)
negative regulation of phagocytosis  (ISO)
negative regulation of synapse assembly  (ISO)
neutrophil migration  (ISO)
NIK/NF-kappaB signaling  (ISO)
nitric oxide biosynthetic process  (ISO)
nitric oxide metabolic process  (IDA)
positive regulation of cellular response to macrophage colony-stimulating factor stimulus  (ISO)
positive regulation of chemokine production  (ISO)
positive regulation of cytokine production  (ISO)
positive regulation of ERK1 and ERK2 cascade  (ISO)
positive regulation of gene expression  (ISO)
positive regulation of inflammatory response  (ISO)
positive regulation of interferon-beta production  (ISO)
positive regulation of interleukin-1 beta production  (ISO)
positive regulation of interleukin-10 production  (IDA)
positive regulation of interleukin-12 production  (ISO)
positive regulation of interleukin-18 production  (ISO)
positive regulation of interleukin-6 production  (ISO)
positive regulation of interleukin-8 production  (ISO)
positive regulation of leukocyte migration  (ISO)
positive regulation of macrophage cytokine production  (ISO)
positive regulation of matrix metallopeptidase secretion  (ISO)
positive regulation of neutrophil migration  (ISO)
positive regulation of NF-kappaB transcription factor activity  (ISO)
positive regulation of NIK/NF-kappaB signaling  (ISO)
positive regulation of nitric oxide biosynthetic process  (ISO)
positive regulation of nitric-oxide synthase biosynthetic process  (ISO)
positive regulation of oligodendrocyte differentiation  (IDA)
positive regulation of toll-like receptor signaling pathway  (ISO)
positive regulation of transcription by RNA polymerase II  (ISO)
positive regulation of tumor necrosis factor production  (ISO)
positive regulation of Wnt signaling pathway  (ISO)
positive regulation of xenophagy  (ISO)
regulation of dendritic cell cytokine production  (ISO)
response to bacterial lipoprotein  (IDA)
response to bacterium  (ISO)
response to fatty acid  (IDA)
response to hypoxia  (IEP)
response to insulin  (IEP)
response to lipopolysaccharide  (IEP)
response to molecule of fungal origin  (ISO)
response to peptidoglycan  (ISO)
response to progesterone  (IEP)
response to toxic substance  (IEP)
toll-like receptor 2 signaling pathway  (IEA)
toll-like receptor signaling pathway  (IBA,IDA,IMP,ISO)
toll-like receptor TLR6:TLR2 signaling pathway  (ISO)
xenophagy  (ISO)

References

References - curated
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Additional References at PubMed
PMID:10384090   PMID:10549626   PMID:11067888   PMID:11274165   PMID:11521063   PMID:11672593   PMID:11986301   PMID:12091878   PMID:12443841   PMID:12594207   PMID:12719478   PMID:15220916  
PMID:15294986   PMID:15356140   PMID:15690042   PMID:16177377   PMID:16489656   PMID:16601243   PMID:16879708   PMID:16880211   PMID:16949315   PMID:16954392   PMID:17027917   PMID:17053043  
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PMID:19115402   PMID:19139201   PMID:19326394   PMID:19454685   PMID:19509287   PMID:19527807   PMID:19740627   PMID:19770268   PMID:19861264   PMID:19930876   PMID:19931471   PMID:20020500  
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Genomics

Candidate Gene Status
Tlr2 is a candidate Gene for QTL Iddm54
Comparative Map Data
Tlr2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22169,200,620 - 169,206,819 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl2169,197,419 - 169,206,630 (-)Ensembl
Rnor_6.02182,840,171 - 182,846,061 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2182,840,727 - 182,846,061 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02202,252,701 - 202,258,962 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42175,607,990 - 175,613,992 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12175,558,096 - 175,564,098 (-)NCBI
Celera2163,202,040 - 163,207,399 (-)NCBICelera
Cytogenetic Map2q34NCBI
TLR2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384153,684,280 - 153,710,637 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl4153,684,070 - 153,706,260 (+)EnsemblGRCh38hg38GRCh38
GRCh374154,605,432 - 154,627,412 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364154,824,891 - 154,846,693 (+)NCBINCBI36hg18NCBI36
Build 344154,966,670 - 154,984,135NCBI
Celera4151,929,928 - 151,951,730 (+)NCBI
Cytogenetic Map4q31.3NCBI
HuRef4150,336,457 - 150,358,268 (+)NCBIHuRef
CHM1_14154,583,811 - 154,605,614 (+)NCBICHM1_1
Tlr2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39383,743,579 - 83,749,045 (-)NCBIGRCm39mm39
GRCm39 Ensembl383,743,579 - 83,749,074 (-)Ensembl
GRCm38383,836,272 - 83,841,824 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl383,836,272 - 83,841,767 (-)EnsemblGRCm38mm10GRCm38
MGSCv37383,640,194 - 83,645,530 (-)NCBIGRCm37mm9NCBIm37
MGSCv36383,922,199 - 83,927,694 (-)NCBImm8
Celera383,852,064 - 83,857,400 (-)NCBICelera
Cytogenetic Map3E3NCBI
Tlr2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554718,014,910 - 8,017,258 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554718,011,710 - 8,019,063 (+)NCBIChiLan1.0ChiLan1.0
TLR2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.14157,848,058 - 157,870,324 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4157,866,977 - 157,869,331 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v04146,024,653 - 146,091,388 (+)NCBIMhudiblu_PPA_v0panPan3
TLR2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11551,454,557 - 51,465,429 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1551,454,695 - 51,465,241 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1551,808,717 - 51,811,083 (+)NCBI
ROS_Cfam_1.01552,140,775 - 52,151,566 (+)NCBI
UMICH_Zoey_3.11551,404,786 - 51,407,152 (+)NCBI
UNSW_CanFamBas_1.01551,510,608 - 51,512,974 (+)NCBI
UU_Cfam_GSD_1.01551,821,784 - 51,824,151 (+)NCBI
Tlr2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530139,016,995 - 39,024,812 (-)NCBI
SpeTri2.0NW_004936576522,234 - 531,660 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TLR2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl875,411,991 - 75,446,850 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1875,416,257 - 75,428,370 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2879,823,867 - 79,834,881 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TLR2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.17100,239,533 - 100,565,955 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl7100,258,441 - 100,260,795 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603779,891,761 - 79,956,832 (+)NCBIVero_WHO_p1.0
Tlr2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248584,931,820 - 4,984,175 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
RH144365  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22169,201,531 - 169,201,724 (+)MAPPERmRatBN7.2
Rnor_6.02182,841,083 - 182,841,275NCBIRnor6.0
Rnor_5.02202,253,613 - 202,253,805UniSTSRnor5.0
RGSC_v3.42175,608,347 - 175,608,539UniSTSRGSC3.4
Celera2163,202,397 - 163,202,589UniSTS
RH 3.4 Map21105.2UniSTS
Cytogenetic Map2q34UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
2293843Kiddil6Kidney dilation QTL 63.1kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)242804607182042367Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)243154682202446871Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)243154682202446871Rat
1354601Slep1Serum leptin concentration QTL 15.39blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)243171017184114403Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)246123260202447032Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)256043031202447032Rat
1298080Bp163Blood pressure QTL 1630.02arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118275202447032Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118463226797303Rat
1354605Rf48Renal function QTL 482.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)274786664206665859Rat
61374Edpm2Estrogen-dependent pituitary mass QTL 24.420.86pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)276539322202447032Rat
1581569Uae32Urinary albumin excretion QTL 320.0001urine protein amount (VT:0005160)urine albumin excretion rate (CMO:0000757)278665619219826953Rat
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)278665619249053267Rat
8662832Vetf7Vascular elastic tissue fragility QTL 73.5aorta elastin amount (VT:0003905)aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)281689826221035911Rat
1354622Kidm16Kidney mass QTL 163kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)281754530222436696Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)281754530227146641Rat
631507Bp105Blood pressure QTL 1050.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2112456140212696837Rat
634308Sach6Saccharin preference QTL 64.9taste sensitivity trait (VT:0001986)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)2112456140212696837Rat
1359030Bp277Blood pressure QTL 277arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2114837527185876470Rat
1359030Bp277Blood pressure QTL 277arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2114837527185876470Rat
1578648Bss11Bone structure and strength QTL 114.7femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)2114837527211674221Rat
1554319Bmd2Bone mineral density QTL 213.40.0001lumbar vertebra area (VT:0010570)lumbar vertebra cross-sectional area (CMO:0001689)2114837675212549332Rat
6907363Bp357Blood pressure QTL 3574.10.002arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2129540907174540907Rat
1300165Rf9Renal function QTL 93.28kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)2133914684202447032Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)2135552573202446871Rat
1298076Bp166Blood pressure QTL 1660.0009arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2136445150202447032Rat
1581502Esta3Estrogen-induced thymic atrophy QTL 3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)2136916935189599348Rat
1359022Ppulsi1Prepulse inhibition QTL 13.63prepulse inhibition trait (VT:0003088)acoustic startle response measurement (CMO:0001519)2136916935213594495Rat
1331794Bp202Blood pressure QTL 2023.66819arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2141194931223265385Rat
1331805Cm29Cardiac mass QTL 293.50746heart mass (VT:0007028)heart wet weight (CMO:0000069)2141194931223265385Rat
71113Cari2Carrageenan-induced inflammation QTL 22.70.009hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)2141596551202447032Rat
724568Uae13Urinary albumin excretion QTL 134.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)2143157029210020885Rat
10043136Iddm54Insulin dependent diabetes mellitus QTL 543.40.0001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2143657411190602963Rat
10043136Iddm54Insulin dependent diabetes mellitus QTL 543.40.0001blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)2143657411190602963Rat
6903312Bw112Body weight QTL 1123.20.0013body mass (VT:0001259)body weight (CMO:0000012)2143657569184114274Rat
61401Niddm2Non-insulin dependent diabetes mellitus QTL 24.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2144599348189599348Rat
1598833Bp295Blood pressure QTL 2953.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2147798556192798556Rat
1641925Alcrsp2Alcohol response QTL 2response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561221167075Rat
1641891Alcrsp17Alcohol response QTL 17response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561249053267Rat
1598805Memor8Memory QTL 83exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)2150341585189039377Rat
631501Bp101Blood pressure QTL 1012.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2150341684202446871Rat
2301966Bp322Blood pressure QTL 3223.58arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2150540301202447032Rat
1354609Niddm62Non-insulin dependent diabetes mellitus QTL 624.720.000006insulin secretion trait (VT:0003564)plasma insulin level (CMO:0000342)2150540301202447032Rat
12879845Cm89Cardiac mass QTL 890.008heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)2152413072175950118Rat
12879846Cm90Cardiac mass QTL 900.011heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)2152413072175950118Rat
12879847Am4Aortic mass QTL 40.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)2152413072175950118Rat
11565180Kidm56Kidney mass QTL 560.003kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2152413072175950118Rat
11565181Bw176Body weight QTL 1760.002body mass (VT:0001259)body weight (CMO:0000012)2152413072175950118Rat
2301415Cm67Cardiac mass QTL 670.003heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)2152413072175950118Rat
12879836Kidm61Kidney mass QTL 610.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2152413072185122374Rat
12879837Am2Aortic mass QTL 20.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)2152413072185122374Rat
12879838Cm86Cardiac mass QTL 860.002heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)2152413072185122374Rat
12879839Cm85Cardiac mass QTL 850.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)2152413072185122374Rat
12879840Bw179Body weight QTL 1790.005body mass (VT:0001259)body weight (CMO:0000012)2152413072185122374Rat
1359032Hrtrt18Heart rate QTL 18heart pumping trait (VT:2000009)heart rate (CMO:0000002)2157142078192625452Rat
1358900Bw48Body weight QTL 484.88body mass (VT:0001259)body weight (CMO:0000012)2157142078211086598Rat
8662843Vetf9Vascular elastic tissue fragility QTL 92.05thoracic aorta molecular composition trait (VT:0010568)aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)2157142078226277316Rat
1302793Bw16Body weight QTL 1650.0001body mass (VT:0001259)body weight (CMO:0000012)2157142209202446871Rat
7488925Bp364Blood pressure QTL 3640.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2160564068205564068Rat
1358356Srcrt1Stress Responsive Cort QTL13.66blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)2161699179222436696Rat
7488927Bp365Blood pressure QTL 3650.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2162765032207765032Rat
2306901Bp337Blood pressure QTL 3370.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2164073756227146641Rat
1598838Bp290Blood pressure QTL 2901.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2166539266211539266Rat
1549833Bp257Blood pressure QTL 2570.003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2168354880185122374Rat
1331734Bp204Blood pressure QTL 2043.61192arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2168358098223265385Rat
2307174Activ3Activity QTL 34.830.000058locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)2168594495213594495Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:121
Count of miRNA genes:103
Interacting mature miRNAs:108
Transcripts:ENSRNOT00000013025
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 8 19 3 5
Low 3 43 45 37 37 8 10 74 35 34 6 8
Below cutoff 4 4 4 1 3

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_198769 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761102 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AY151255 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY151256 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473976 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF127847 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF127848 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730127 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730128 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730129 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730130 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730131 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730132 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730133 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730134 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730135 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730136 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730137 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730138 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730139 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730140 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730141 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730142 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730143 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730144 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730145 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730146 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730147 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730148 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730149 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730150 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730151 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730153 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730154 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730155 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730156 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730157 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730158 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730159 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730160 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730161 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730162 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730163 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730164 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730165 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730167 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730168 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730169 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730170 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730171 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730172 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730173 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730174 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730175 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730178 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730179 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730180 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730181 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730182 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730183 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730184 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730185 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730186 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730187 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730188 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730189 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730190 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730191 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730192 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730193 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730194 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730195 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730196 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730197 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730198 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730199 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730200 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730201 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730202 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730203 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730204 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730205 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730206 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730207 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730208 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730209 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730210 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730211 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730212 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730214 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730216 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730217 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730218 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730219 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730220 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730221 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730222 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730223 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730224 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730225 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730226 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730227 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730228 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730229 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730230 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730231 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730232 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730233 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730234 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730235 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730237 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730238 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730240 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000013025   ⟹   ENSRNOP00000013025
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2169,198,149 - 169,206,630 (-)Ensembl
Rnor_6.0 Ensembl2182,840,727 - 182,846,061 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000097289   ⟹   ENSRNOP00000095767
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2169,197,419 - 169,206,630 (-)Ensembl
RefSeq Acc Id: NM_198769   ⟹   NP_942064
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22169,201,175 - 169,206,545 (-)NCBI
Rnor_6.02182,840,726 - 182,846,061 (-)NCBI
Rnor_5.02202,252,701 - 202,258,962 (-)NCBI
RGSC_v3.42175,607,990 - 175,613,992 (-)RGD
Celera2163,202,040 - 163,207,399 (-)RGD
Sequence:
RefSeq Acc Id: XM_008761102   ⟹   XP_008759324
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22169,200,620 - 169,206,819 (-)NCBI
Rnor_6.02182,840,171 - 182,846,006 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_942064 (Get FASTA)   NCBI Sequence Viewer  
  XP_008759324 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAN86524 (Get FASTA)   NCBI Sequence Viewer  
  AAN86525 (Get FASTA)   NCBI Sequence Viewer  
  ABL75415 (Get FASTA)   NCBI Sequence Viewer  
  ABL75416 (Get FASTA)   NCBI Sequence Viewer  
  EDM00832 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42660 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42661 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42662 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42663 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42664 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42665 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42666 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42667 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42668 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42669 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42670 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42671 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42672 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42673 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42674 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42675 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42676 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42677 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42678 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42679 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42680 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42681 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42682 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42683 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42684 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42685 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42686 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42687 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42688 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42689 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42690 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42691 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42692 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42693 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42694 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42695 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42696 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42697 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42698 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42699 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42700 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42701 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42702 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42703 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42704 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42705 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42706 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42707 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42708 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42709 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42710 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42711 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42712 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42713 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42714 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42715 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42716 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42717 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42718 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42719 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42720 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42721 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42722 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42723 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42724 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42725 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42726 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42727 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42728 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42729 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42730 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42731 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42732 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42733 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42734 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42735 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42736 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42737 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42738 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42739 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42740 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42741 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42742 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42743 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42744 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42745 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42746 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42747 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42748 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42749 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42750 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42751 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42752 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42753 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42754 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42755 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42756 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42757 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42758 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42759 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42760 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42761 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42762 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42763 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42764 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42765 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42766 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42767 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42768 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42769 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42770 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42771 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42772 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42773 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_942064   ⟸   NM_198769
- Peptide Label: precursor
- UniProtKB: Q6YGU2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008759324   ⟸   XM_008761102
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000013025   ⟸   ENSRNOT00000013025
RefSeq Acc Id: ENSRNOP00000095767   ⟸   ENSRNOT00000097289
Protein Domains
TIR

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-E9PTD9-F1-model_v2 AlphaFold E9PTD9 1-784 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691399
Promoter ID:EPDNEW_R1924
Type:initiation region
Name:Tlr2_1
Description:toll-like receptor 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02182,846,087 - 182,846,147EPDNEW

Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:735138 AgrOrtholog
BioCyc Gene G2FUF-52648 BioCyc
Ensembl Genes ENSRNOG00000009822 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000013025 UniProtKB/TrEMBL
  ENSRNOP00000095767 ENTREZGENE
Ensembl Transcript ENSRNOT00000013025 UniProtKB/TrEMBL
  ENSRNOT00000097289 ENTREZGENE
Gene3D-CATH 3.40.50.10140 UniProtKB/TrEMBL
  3.80.10.10 UniProtKB/TrEMBL
InterPro Cys-rich_flank_reg_C UniProtKB/TrEMBL
  L_dom-like UniProtKB/TrEMBL
  Leu-rich_rpt UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/TrEMBL
  TLR2 UniProtKB/TrEMBL
  Toll-Interleukin_rcpt UniProtKB/TrEMBL
  Toll-like_receptor UniProtKB/TrEMBL
  Toll_tir_struct_dom_sf UniProtKB/TrEMBL
KEGG Report rno:310553 UniProtKB/TrEMBL
NCBI Gene 310553 ENTREZGENE
PANTHER PTHR24365 UniProtKB/TrEMBL
  PTHR24365:SF17 UniProtKB/TrEMBL
Pfam LRR_8 UniProtKB/TrEMBL
  TIR UniProtKB/TrEMBL
PhenoGen Tlr2 PhenoGen
PIRSF Toll-like_receptor UniProtKB/TrEMBL
PROSITE LRR UniProtKB/TrEMBL
  TIR UniProtKB/TrEMBL
SMART LRR_TYP UniProtKB/TrEMBL
  LRRCT UniProtKB/TrEMBL
  TIR UniProtKB/TrEMBL
Superfamily-SCOP TIR UniProtKB/TrEMBL
UniProt E9PTD9_RAT UniProtKB/TrEMBL
  Q6YGU2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Tlr2  toll-like receptor 2    toll-like receptor 2 variant 1  Name updated 1299863 APPROVED