(+)-pilocarpine increases expression ISO RGD:1551003 6480464 Pilocarpine results in increased expression of TLR2 mRNA CTD PMID:15193289 (-)-citrinin increases expression ISO RGD:1551003 6480464 Citrinin results in increased expression of TLR2 mRNA CTD PMID:22771370 (-)-epigallocatechin 3-gallate multiple interactions ISO RGD:1551003 6480464 epigallocatechin gallate inhibits the reaction [Paraquat results in increased expression of TLR2 protein] CTD PMID:27890776 (-)-epigallocatechin 3-gallate multiple interactions ISO RGD:1353654 6480464 epigallocatechin gallate inhibits the reaction [Paraquat results in increased expression of TLR2 protein] CTD PMID:27890776 (RS)-amphetamine increases expression EXP 6480464 Amphetamine results in increased expression of TLR2 mRNA CTD PMID:30779732 (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of TLR2 mRNA CTD PMID:25729387 (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE increases expression EXP 6480464 Topotecan results in increased expression of TLR2 mRNA CTD PMID:25729387 1,1-dichloroethene increases expression ISO RGD:1551003 6480464 vinylidene chloride results in increased expression of TLR2 mRNA CTD PMID:26682919 1-chloro-2,4,6-trinitrobenzene multiple interactions ISO RGD:1551003 6480464 TLR2 protein affects the reaction [TLR4 protein results in increased susceptibility to Picryl Chloride] CTD PMID:18725520 15-deoxy-Delta(12,14)-prostaglandin J2 multiple interactions ISO RGD:1353654 6480464 15-deoxy-delta(12, 14)-prostaglandin J2 inhibits the reaction [Lipopolysaccharides results in increased expression of TLR2 mRNA] CTD PMID:20174873 15-deoxy-Delta(12,14)-prostaglandin J2 decreases expression ISO RGD:1353654 6480464 15-deoxy-delta(12, 14)-prostaglandin J2 results in decreased expression of TLR2 mRNA CTD PMID:20174873 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of TLR2 mRNA CTD PMID:17557909 17beta-estradiol multiple interactions ISO RGD:1353654 6480464 [Estradiol co-treated with TGFB1 protein] results in increased expression of TLR2 mRNA, [Progesterone co-treated with Estradiol] results in increased expression of TLR2 mRNA CTD PMID:17404688 , PMID:30165855 17beta-estradiol increases expression ISO RGD:1551003 6480464 Estradiol results in increased expression of TLR2 mRNA CTD PMID:19484750 17beta-estradiol increases expression ISO RGD:1353654 6480464 Estradiol results in increased expression of TLR2 mRNA CTD PMID:23373633 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1551003 6480464 Tetrachlorodibenzodioxin affects the expression of TLR2 mRNA CTD PMID:21570461 2,4,6-trinitrobenzenesulfonic acid increases expression EXP 6480464 Trinitrobenzenesulfonic Acid results in increased expression of TLR2 CTD PMID:16891783 2-HYDROXY-(5-([4-(2-PYRIDINYLAMINO)SULFONYL]PHENYL)AZO)BENZOIC ACID multiple interactions ISO RGD:1551003 6480464 Sulfasalazine inhibits the reaction [Lipopolysaccharides results in increased expression of TLR2 mRNA] CTD PMID:12888452 3,3',5,5'-tetrabromobisphenol A increases expression ISO RGD:1353654 6480464 tetrabromobisphenol A results in increased expression of TLR2 mRNA CTD PMID:25461914 3-mercaptopropanoic acid multiple interactions ISO RGD:1551003 6480464 [3-Mercaptopropionic Acid co-treated with cadmium telluride] results in increased expression of TLR2 protein CTD PMID:29852215 4,4'-diaminodiphenylmethane increases expression EXP 6480464 4, 4'-diaminodiphenylmethane results in increased expression of TLR2 mRNA CTD PMID:30723492 4-hydroxyphenyl retinamide increases expression ISO RGD:1551003 6480464 Fenretinide results in increased expression of TLR2 mRNA CTD PMID:28973697 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of TLR2 mRNA CTD PMID:24780913 6alpha-methylprednisolone decreases expression ISO RGD:1353654 6480464 Methylprednisolone results in decreased expression of TLR2 mRNA CTD PMID:19192274 adapalene decreases expression ISO RGD:1353654 6480464 Adapalene results in decreased expression of TLR2 protein CTD PMID:17518990 afimoxifene increases expression ISO RGD:1353654 6480464 afimoxifene results in increased expression of TLR2 mRNA CTD PMID:23373633 aflatoxin B1 increases expression ISO RGD:1551003 6480464 Aflatoxin B1 results in increased expression of TLR2 mRNA, Aflatoxin B1 results in increased expression of TLR2 protein CTD PMID:22445859 , PMID:28789997 aflatoxin B2 multiple interactions ISO RGD:1551003 6480464 aflatoxin B2 inhibits the reaction [Lipopolysaccharides results in increased expression of TLR2 protein] CTD PMID:22445859 Aflatoxin G1 multiple interactions ISO RGD:1551003 6480464 aflatoxin G1 inhibits the reaction [Lipopolysaccharides results in increased expression of TLR2 protein] CTD PMID:22445859 aldehydo-D-glucose decreases expression ISO RGD:1353654 6480464 Glucose results in decreased expression of TLR2 protein CTD PMID:20200188 alfacalcidol decreases expression ISO RGD:1353654 6480464 alfacalcidol results in decreased expression of TLR2 protein CTD PMID:15946915 all-trans-retinol increases expression ISO RGD:1353654 6480464 Vitamin A results in increased expression of TLR2 mRNA CTD PMID:17033190 ammonium hexachloroplatinate affects expression ISO RGD:1353654 6480464 ammonium hexachloroplatinate affects the expression of TLR2 mRNA CTD PMID:19110044 antirheumatic drug decreases expression ISO RGD:1353654 6480464 Antirheumatic Agents results in decreased expression of TLR2 mRNA CTD PMID:24449571 astemizole decreases expression EXP 6480464 Astemizole results in decreased expression of TLR2 mRNA CTD PMID:20221588 atorvastatin calcium increases expression ISO RGD:1353654 6480464 Atorvastatin results in increased expression of TLR2 protein CTD PMID:16387846 azathioprine decreases expression ISO RGD:1353654 6480464 Azathioprine results in decreased expression of TLR2 mRNA CTD PMID:19192274 azathioprine increases expression ISO RGD:1551003 6480464 Azathioprine results in increased expression of TLR2 mRNA CTD PMID:24184165 benzene increases expression ISO RGD:1353654 6480464 Benzene results in increased expression of TLR2 mRNA CTD PMID:15929907 , PMID:19162166 benzo[a]pyrene increases expression ISO RGD:1551003 6480464 Benzo(a)pyrene results in increased expression of TLR2 mRNA CTD PMID:22228805 beta-naphthoflavone multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of TLR2 mRNA CTD PMID:18164116 bis(2-chloroethyl) sulfide increases expression ISO RGD:1551003 6480464 Mustard Gas results in increased expression of TLR2 mRNA CTD PMID:18955075 bisdemethoxycurcumin multiple interactions ISO RGD:1353654 6480464 [bis(4-hydroxycinnamoyl)methane analog co-treated with APP protein] results in increased expression of TLR2 mRNA, [bis(4-hydroxycinnamoyl)methane co-treated with APP protein] results in increased expression of TLR2 mRNA CTD PMID:22029407 bisphenol A decreases expression ISO RGD:1353654 6480464 bisphenol A results in decreased expression of TLR2 mRNA CTD PMID:20678512 bisphenol A decreases expression ISO RGD:1551003 6480464 bisphenol A results in decreased expression of TLR2 mRNA CTD PMID:25594700 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of TLR2 mRNA CTD PMID:25181051 Bisphenol A diglycidyl ether multiple interactions EXP 6480464 2 more ... CTD PMID:24612634 bortezomib multiple interactions ISO RGD:1353654 6480464 Bortezomib inhibits the reaction [arsenic trioxide results in decreased expression of TLR2 mRNA] CTD PMID:20471514 bortezomib increases expression ISO RGD:1353654 6480464 Bortezomib results in increased expression of TLR2 mRNA CTD PMID:20471514 butanal increases expression ISO RGD:1353654 6480464 butyraldehyde results in increased expression of TLR2 mRNA CTD PMID:26079696 cadmium dichloride decreases expression ISO RGD:1551003 6480464 Cadmium Chloride results in decreased expression of TLR2 mRNA CTD PMID:20061341 cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of TLR2 mRNA CTD PMID:29286200 carbon nanotube multiple interactions ISO RGD:1353654 6480464 Nanotubes, Carbon inhibits the reaction [TLR2 protein results in increased secretion of IL10 protein] more ... CTD PMID:23266719 carbon nanotube increases activity ISO RGD:1353654 6480464 Nanotubes, Carbon results in increased activity of TLR2 protein CTD PMID:29348435 carbon nanotube increases expression ISO RGD:1551003 6480464 Nanotubes, Carbon analog results in increased expression of TLR2 mRNA, Nanotubes, Carbon results in increased expression of TLR2 mRNA CTD PMID:25554681 cefaloridine increases expression EXP 6480464 Cephaloridine results in increased expression of TLR2 mRNA CTD PMID:18500788 cerium trichloride increases expression ISO RGD:1551003 6480464 cerous chloride results in increased expression of TLR2 mRNA, cerous chloride results in increased expression of TLR2 protein CTD PMID:21656643 chitosan multiple interactions ISO RGD:1353654 6480464 Chitosan inhibits the reaction [Lipopolysaccharides results in decreased expression of TLR2 mRNA] CTD PMID:21329777 chitosan decreases expression ISO RGD:1353654 6480464 Chitosan results in decreased expression of TLR2 mRNA CTD PMID:21329777 chlorpyrifos decreases expression EXP 6480464 Chlorpyrifos results in decreased expression of TLR2 CTD PMID:25643018 ciguatoxin CTX1B affects expression ISO RGD:1551003 6480464 Ciguatoxins affects the expression of TLR2 mRNA CTD PMID:18353800 cisplatin increases expression ISO RGD:1353654 6480464 Cisplatin results in increased expression of TLR2 protein CTD PMID:16803524 cisplatin increases expression ISO RGD:1551003 6480464 Cisplatin results in increased expression of TLR2 mRNA CTD PMID:26546572 cobalt atom multiple interactions ISO RGD:1353654 6480464 [tungsten carbide co-treated with Cobalt] results in decreased expression of TLR2 mRNA CTD PMID:18078969 cobalt(2+) multiple interactions ISO RGD:1353654 6480464 [tungsten carbide co-treated with Cobalt] results in decreased expression of TLR2 mRNA CTD PMID:18078969 cortisol increases expression ISO RGD:1353654 6480464 Hydrocortisone results in increased expression of TLR2 mRNA CTD PMID:17033190 crocidolite asbestos increases expression ISO RGD:1353654 6480464 Asbestos, Crocidolite results in increased expression of TLR2 mRNA CTD PMID:23634900 , PMID:25351596 curcumin multiple interactions EXP 6480464 Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of TLR2 mRNA], Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of TLR2 protein] CTD PMID:22683883 curcumin multiple interactions ISO RGD:1353654 6480464 Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of TLR2 mRNA] CTD PMID:23452621 cyclosporin A increases expression ISO RGD:1353654 6480464 Cyclosporine results in increased expression of TLR2 mRNA CTD PMID:20106945 , PMID:27989131 cyproconazole increases expression ISO RGD:1551003 6480464 cyproconazole results in increased expression of TLR2 mRNA CTD PMID:22334560 D-glucose decreases expression ISO RGD:1353654 6480464 Glucose results in decreased expression of TLR2 protein CTD PMID:20200188 deoxynivalenol decreases expression ISO RGD:1551003 6480464 deoxynivalenol results in decreased expression of TLR2 mRNA CTD PMID:22968694 dichloroacetic acid increases expression ISO RGD:1551003 6480464 Dichloroacetic Acid results in increased expression of TLR2 mRNA CTD PMID:28962523 diclofenac decreases expression ISO RGD:1353654 6480464 Diclofenac results in decreased expression of TLR2 mRNA CTD PMID:19192274 diclofenac increases expression ISO RGD:1551003 6480464 Diclofenac results in increased expression of TLR2 mRNA CTD PMID:26934552 dioxygen multiple interactions ISO RGD:1353654 6480464 3 more ... CTD PMID:23452621 dioxygen increases expression ISO RGD:1353654 6480464 Oxygen deficiency results in increased expression of TLR2 mRNA CTD PMID:23452621 disodium selenite decreases expression ISO RGD:1551003 6480464 Sodium Selenite results in decreased expression of TLR2 mRNA CTD PMID:23274088 dopamine increases expression EXP 6480464 Dopamine results in increased expression of TLR2 mRNA CTD PMID:21983523 doxorubicin multiple interactions ISO RGD:1551003 6480464 TLR2 gene mutant form inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein] more ... CTD PMID:15505089 doxorubicin increases expression ISO RGD:1353654 6480464 Doxorubicin results in increased expression of TLR2 mRNA, Doxorubicin results in increased expression of TLR2 protein CTD PMID:29959987 doxorubicin multiple interactions EXP 6480464 [Doxorubicin co-treated with Fungal Polysaccharides] results in decreased expression of TLR2 mRNA CTD PMID:27181935 doxorubicin decreases response to substance ISO RGD:1551003 6480464 TLR2 gene mutant form results in decreased susceptibility to Doxorubicin CTD PMID:15505089 endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of TLR2 mRNA CTD PMID:29391264 epoxiconazole increases expression ISO RGD:1551003 6480464 epoxiconazole results in increased expression of TLR2 mRNA CTD PMID:22334560 fenoldopam increases expression EXP 6480464 Fenoldopam results in increased expression of TLR2 mRNA CTD PMID:21983523 ferric oxide increases expression ISO RGD:1551003 6480464 ferric oxide analog results in increased expression of TLR2 mRNA CTD PMID:24525745 ferulic acid multiple interactions ISO RGD:1551003 6480464 ferulic acid inhibits the reaction [Carbon Tetrachloride results in increased expression of TLR2 mRNA], ferulic acid inhibits the reaction [Carbon Tetrachloride results in increased expression of TLR2 protein] CTD PMID:21291945 fonofos increases methylation ISO RGD:1353654 6480464 Fonofos results in increased methylation of TLR2 promoter CTD PMID:22847954 furan increases methylation EXP 6480464 furan results in increased methylation of TLR2 gene CTD PMID:22079235 genistein multiple interactions ISO RGD:1353654 6480464 Genistein inhibits the reaction [Oxygen deficiency results in increased expression of TLR2 mRNA] CTD PMID:23452621 glucose decreases expression ISO RGD:1353654 6480464 Glucose results in decreased expression of TLR2 protein CTD PMID:20200188 glutathione decreases expression ISO RGD:1353654 6480464 Glutathione results in decreased expression of TLR2 mRNA CTD PMID:22385246 gold atom increases expression ISO RGD:1353654 6480464 Gold results in increased expression of TLR2 mRNA CTD PMID:29705079 gold atom multiple interactions ISO RGD:1353654 6480464 Gold promotes the reaction [SAA1 protein binds to TLR2 protein] CTD PMID:29705079 gold(0) increases expression ISO RGD:1353654 6480464 Gold results in increased expression of TLR2 mRNA CTD PMID:29705079 gold(0) multiple interactions ISO RGD:1353654 6480464 Gold promotes the reaction [SAA1 protein binds to TLR2 protein] CTD PMID:29705079 gold(1+) multiple interactions ISO RGD:1353654 6480464 Gold promotes the reaction [SAA1 protein binds to TLR2 protein] CTD PMID:29705079 gold(1+) increases expression ISO RGD:1353654 6480464 Gold results in increased expression of TLR2 mRNA CTD PMID:29705079 hexamethylene diisocyanate affects expression ISO RGD:1353654 6480464 1, 6-hexamethylene diisocyanate affects the expression of TLR2 mRNA CTD PMID:19110044 histamine multiple interactions ISO RGD:1353654 6480464 Histamine promotes the reaction [[TLR2 results in increased expression of PTGS2] which results in increased chemical synthesis of Dinoprostone] more ... CTD PMID:20040740 hyaluronic acid increases expression ISO RGD:1551003 6480464 Hyaluronic Acid metabolite results in increased expression of TLR2 mRNA, Hyaluronic Acid metabolite results in increased expression of TLR2 protein CTD PMID:23692848 hyaluronic acid multiple interactions ISO RGD:1551003 6480464 Mn(III) 5 more ... CTD PMID:23692848 hydroxycitronellal increases expression ISO RGD:1353654 6480464 hydroxycitronellal results in increased expression of TLR2 mRNA CTD PMID:17936526 icosanoid multiple interactions ISO RGD:1551003 6480464 TLR2 protein promotes the reaction [Pam(3)CSK(4) peptide results in increased metabolism of Eicosanoids], TLR2 protein promotes the reaction [Peptidoglycan results in increased metabolism of Eicosanoids] CTD PMID:17369491 iron(2+) sulfate (anhydrous) multiple interactions ISO RGD:1551003 6480464 [Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TLR2 mRNA more ... CTD PMID:23692848 isoeugenol increases expression ISO RGD:1353654 6480464 isoeugenol results in increased expression of TLR2 mRNA CTD PMID:17936526 ivermectin decreases expression ISO RGD:1353654 6480464 Ivermectin results in decreased expression of TLR2 protein CTD PMID:28653460 kaempferol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside multiple interactions ISO RGD:1353654 6480464 kaempferol 3-O-sophoroside inhibits the reaction [HMGB1 protein results in increased expression of TLR2 protein] CTD PMID:22178603 L-ascorbic acid multiple interactions ISO RGD:1551003 6480464 [Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TLR2 mRNA more ... CTD PMID:23692848 lipophosphoglycan increases response to substance ISO RGD:1551003 6480464 TLR2 protein results in increased susceptibility to lipopeptidophosphoglycan CTD PMID:15910421 lipophosphoglycan multiple interactions ISO RGD:1551003 6480464 lipopeptidophosphoglycan binds to and results in increased activity of TLR2 protein CTD PMID:15910421 lipophosphoglycan multiple interactions ISO RGD:1353654 6480464 [lipopeptidophosphoglycan binds to and results in increased activity of TLR2 protein] results in increased activity of [NFKB1 protein binds to RELA protein] more ... CTD PMID:15910421 lipopolysaccharide multiple interactions ISO RGD:1353654 6480464 15-deoxy-delta(12 more ... CTD PMID:12734376 more ... lipopolysaccharide increases expression EXP 6480464 Lipopolysaccharides results in increased expression of TLR2 mRNA CTD PMID:21051124 lipopolysaccharide multiple interactions EXP 6480464 [Lipopolysaccharides co-treated with Titanium] results in increased expression of TLR2 mRNA, tributyrin inhibits the reaction [Lipopolysaccharides results in increased expression of TLR2 mRNA] CTD PMID:21051124 , PMID:21308757 lipopolysaccharide affects response to substance ISO RGD:1551003 6480464 TLR2 protein affects the susceptibility to Lipopolysaccharides CTD PMID:15593098 lipopolysaccharide increases expression ISO RGD:1551003 6480464 Lipopolysaccharides results in increased expression of TLR2 mRNA, Lipopolysaccharides results in increased expression of TLR2 protein CTD PMID:10823826 more ... lipopolysaccharide multiple interactions ISO RGD:1551003 6480464 [Lipopolysaccharides co-treated with Ozone] results in increased expression of TLR2 mRNA more ... CTD PMID:12888452 more ... lipopolysaccharide increases expression ISO RGD:1353654 6480464 Lipopolysaccharides results in increased expression of TLR2 mRNA, Lipopolysaccharides results in increased expression of TLR2 protein CTD PMID:12176910 more ... lipopolysaccharide decreases expression ISO RGD:1353654 6480464 Lipopolysaccharides results in decreased expression of TLR2 mRNA CTD PMID:21329777 lipoteichoic acid increases activity ISO RGD:1551003 6480464 lipoteichoic acid results in increased activity of TLR2 protein CTD PMID:28003376 lipoteichoic acid multiple interactions ISO RGD:1551003 6480464 [lipoteichoic acid binds to and results in increased activity of TLR2 protein] which results in increased expression of TNF mRNA more ... CTD PMID:18845389 , PMID:19573522 lipoteichoic acid increases activity ISO RGD:1353654 6480464 lipoteichoic acid results in increased activity of TLR2 protein CTD PMID:28003376 lycopene multiple interactions ISO RGD:1353654 6480464 lycopene inhibits the reaction [HMGB1 protein results in increased expression of TLR2 protein], lycopene inhibits the reaction [Lipopolysaccharides results in increased expression of TLR2 protein] CTD PMID:22429818 metformin multiple interactions ISO RGD:1353654 6480464 [Paclitaxel co-treated with Metformin] results in increased expression of TLR2 mRNA CTD PMID:29309887 methamphetamine multiple interactions EXP 6480464 [Methamphetamine co-treated with SCH 23390] results in decreased expression of TLR2 mRNA CTD PMID:19564919 methamphetamine decreases expression EXP 6480464 Methamphetamine results in decreased expression of TLR2 mRNA CTD PMID:19564919 methotrexate decreases expression ISO RGD:1353654 6480464 Methotrexate results in decreased expression of TLR2 mRNA CTD PMID:19192274 methotrexate multiple interactions ISO RGD:1353654 6480464 [Methotrexate analog binds to Lipids] which results in decreased expression of TLR2 mRNA CTD PMID:24065615 methotrexate increases expression ISO RGD:1353654 6480464 Methotrexate results in increased expression of TLR2 mRNA CTD PMID:21678067 methylseleninic acid increases expression ISO RGD:1353654 6480464 methylselenic acid results in increased expression of TLR2 mRNA CTD PMID:12517777 muramyl dipeptide increases activity ISO RGD:1353654 6480464 Acetylmuramyl-Alanyl-Isoglutamine analog results in increased activity of TLR2 protein CTD PMID:15905553 muramyl dipeptide increases response to substance ISO RGD:1551003 6480464 TLR2 protein results in increased susceptibility to Acetylmuramyl-Alanyl-Isoglutamine analog CTD PMID:15905553 muramyl dipeptide increases activity ISO RGD:1551003 6480464 Acetylmuramyl-Alanyl-Isoglutamine analog results in increased activity of TLR2 protein CTD PMID:15905553 N-acetyl-L-cysteine decreases expression ISO RGD:1353654 6480464 Acetylcysteine results in decreased expression of TLR2 mRNA CTD PMID:22385246 N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of TLR2 mRNA CTD PMID:18164116 nickel atom increases expression ISO RGD:1353654 6480464 Nickel results in increased expression of TLR2 mRNA CTD PMID:25583101 nitrites multiple interactions ISO RGD:1551003 6480464 TLR2 protein affects the reaction [lipoteichoic acid results in increased abundance of Nitrites] CTD PMID:19573522 nitroprusside multiple interactions ISO RGD:1551003 6480464 [Nitroprusside co-treated with TNF co-treated with IFNG] results in increased expression of TLR2 mRNA CTD PMID:15153526 o-anisidine decreases expression ISO RGD:1353654 6480464 2-anisidine results in decreased expression of TLR2 mRNA CTD PMID:28089782 oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of TLR2 mRNA CTD PMID:25729387 ozone multiple interactions ISO RGD:1551003 6480464 [Lipopolysaccharides co-treated with Ozone] results in increased expression of TLR2 mRNA more ... CTD PMID:16864405 more ... ozone decreases response to substance ISO RGD:1551003 6480464 TLR2 gene mutant form results in decreased susceptibility to Ozone CTD PMID:17626835 ozone increases expression ISO RGD:1551003 6480464 Ozone results in increased expression of TLR2 mRNA CTD PMID:17626835 paclitaxel multiple interactions ISO RGD:1353654 6480464 [Paclitaxel co-treated with Metformin] results in increased expression of TLR2 mRNA CTD PMID:29309887 paracetamol affects expression ISO RGD:1551003 6480464 Acetaminophen affects the expression of TLR2 mRNA CTD PMID:17562736 paracetamol increases expression ISO RGD:1353654 6480464 Acetaminophen results in increased expression of TLR2 mRNA CTD PMID:29067470 paraquat multiple interactions ISO RGD:1551003 6480464 epigallocatechin gallate inhibits the reaction [Paraquat results in increased expression of TLR2 protein] CTD PMID:27890776 paraquat decreases expression ISO RGD:1551003 6480464 Paraquat results in decreased expression of TLR2 mRNA CTD PMID:28012437 paraquat increases expression ISO RGD:1551003 6480464 Paraquat results in increased expression of TLR2 protein CTD PMID:27890776 paraquat multiple interactions ISO RGD:1353654 6480464 epigallocatechin gallate inhibits the reaction [Paraquat results in increased expression of TLR2 protein] CTD PMID:27890776 paraquat increases expression ISO RGD:1353654 6480464 Paraquat results in increased expression of TLR2 protein CTD PMID:27890776 parathion increases methylation ISO RGD:1353654 6480464 Parathion results in increased methylation of TLR2 promoter CTD PMID:22847954 pentachlorophenol increases expression ISO RGD:1551003 6480464 Pentachlorophenol results in increased expression of TLR2 mRNA CTD PMID:23892564 pentanal increases expression ISO RGD:1353654 6480464 pentanal results in increased expression of TLR2 mRNA CTD PMID:26079696 pentane-2,3-dione decreases expression EXP 6480464 2, 3-pentanedione results in decreased expression of TLR2 mRNA CTD PMID:25710175 peptidoglycan multiple interactions ISO RGD:1551003 6480464 Peptidoglycan binds to and results in increased activity of TLR2 protein, TLR2 protein promotes the reaction [Peptidoglycan results in increased metabolism of Eicosanoids] CTD PMID:15593098 , PMID:17369491 peptidoglycan affects response to substance ISO RGD:1551003 6480464 TLR2 protein affects the susceptibility to Peptidoglycan CTD PMID:15593098 peptidoglycan increases expression ISO RGD:1551003 6480464 Peptidoglycan results in increased expression of TLR2 mRNA, Peptidoglycan results in increased expression of TLR2 protein CTD PMID:15593098 peptidoglycan multiple interactions ISO RGD:1353654 6480464 Peptidoglycan binds to and results in increased activity of TLR2 protein CTD PMID:12734376 phenobarbital affects expression ISO RGD:1353654 6480464 Phenobarbital affects the expression of TLR2 mRNA CTD PMID:19159669 phenytoin increases expression ISO RGD:1551003 6480464 Phenytoin results in increased expression of TLR2 mRNA CTD PMID:23986454 phenytoin multiple interactions ISO RGD:1551003 6480464 [Phenytoin co-treated with Buthionine Sulfoximine] results in increased expression of TLR2 mRNA CTD PMID:23986454 phorbol 13-acetate 12-myristate increases expression ISO RGD:1353654 6480464 Tetradecanoylphorbol Acetate results in increased expression of TLR2 protein CTD PMID:28720485 pirinixic acid multiple interactions ISO RGD:1551003 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of TLR2 mRNA CTD PMID:19710929 piroxicam decreases expression ISO RGD:1353654 6480464 Piroxicam results in decreased expression of TLR2 mRNA CTD PMID:19192274 poly(I:C) increases expression ISO RGD:1353654 6480464 Poly I-C results in increased expression of TLR2 mRNA CTD PMID:17669408 prednisolone decreases expression ISO RGD:1353654 6480464 Prednisolone results in decreased expression of TLR2 mRNA CTD PMID:19192274 progesterone multiple interactions ISO RGD:1353654 6480464 [Progesterone co-treated with Estradiol] results in increased expression of TLR2 mRNA CTD PMID:17404688 progesterone increases expression ISO RGD:1551003 6480464 Progesterone results in increased expression of TLR2 mRNA, Progesterone results in increased expression of TLR2 protein CTD PMID:21549006 progesterone increases expression ISO RGD:1353654 6480464 Progesterone results in increased expression of TLR2 mRNA CTD PMID:17404688 propanal increases expression ISO RGD:1353654 6480464 propionaldehyde results in increased expression of TLR2 mRNA CTD PMID:26079696 propiconazole increases expression ISO RGD:1551003 6480464 propiconazole results in increased expression of TLR2 mRNA CTD PMID:21278054 more ... prostaglandin E2 multiple interactions ISO RGD:1353654 6480464 [TLR2 results in increased expression of PTGS2] which results in increased chemical synthesis of Dinoprostone, Histamine promotes the reaction [[TLR2 results in increased expression of PTGS2] which results in increased chemical synthesis of Dinoprostone] CTD PMID:20040740 quercetin decreases expression ISO RGD:1353654 6480464 Quercetin results in decreased expression of TLR2 mRNA CTD PMID:20828867 quercetin multiple interactions ISO RGD:1551003 6480464 Quercetin inhibits the reaction [Carbon Tetrachloride results in increased expression of TLR2 mRNA], Quercetin inhibits the reaction [Carbon Tetrachloride results in increased expression of TLR2 protein] CTD PMID:26218279 , PMID:27601294 reactive oxygen species decreases expression ISO RGD:1353654 6480464 Reactive Oxygen Species results in decreased expression of TLR2 mRNA CTD PMID:25800948 resveratrol increases expression EXP 6480464 resveratrol results in increased expression of TLR2 mRNA CTD PMID:25905778 resveratrol multiple interactions ISO RGD:1353654 6480464 [resveratrol co-treated with TLR2 protein] results in decreased secretion of IL10 protein more ... CTD PMID:23452621 , PMID:24035785 resveratrol decreases activity ISO RGD:1353654 6480464 resveratrol results in decreased activity of TLR2 protein CTD PMID:24617573 S-butyl-DL-homocysteine (S,R)-sulfoximine multiple interactions ISO RGD:1551003 6480464 [Phenytoin co-treated with Buthionine Sulfoximine] results in increased expression of TLR2 mRNA CTD PMID:23986454 SB 203580 multiple interactions ISO RGD:1551003 6480464 SB 203580 inhibits the reaction [Lipopolysaccharides results in increased expression of TLR2 mRNA] CTD PMID:12888452 SCH 23390 multiple interactions EXP 6480464 [Methamphetamine co-treated with SCH 23390] results in decreased expression of TLR2 mRNA CTD PMID:19564919 silicon dioxide increases expression EXP 6480464 Silicon Dioxide results in increased expression of TLR2 mRNA CTD PMID:21602193 silicon dioxide increases expression ISO RGD:1353654 6480464 Silicon Dioxide results in increased expression of TLR2 mRNA CTD PMID:25351596 silicon dioxide increases expression ISO RGD:1551003 6480464 Silicon Dioxide results in increased expression of TLR2 mRNA CTD PMID:23221170 simvastatin increases expression ISO RGD:1353654 6480464 Simvastatin results in increased expression of TLR2 protein CTD PMID:16387846 simvastatin multiple interactions ISO RGD:1353654 6480464 Simvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of TLR2 protein] CTD PMID:16443229 sodium aurothiomalate decreases expression ISO RGD:1353654 6480464 Gold Sodium Thiomalate results in decreased expression of TLR2 mRNA CTD PMID:19192274 sodium dichromate decreases expression EXP 6480464 sodium bichromate results in decreased expression of TLR2 mRNA CTD PMID:22561333 sodium dodecyl sulfate increases expression ISO RGD:1353654 6480464 Sodium Dodecyl Sulfate results in increased expression of TLR2 mRNA CTD PMID:17936526 sulfasalazine multiple interactions ISO RGD:1551003 6480464 Sulfasalazine inhibits the reaction [Lipopolysaccharides results in increased expression of TLR2 mRNA] CTD PMID:12888452 sulindac multiple interactions EXP 6480464 [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of TLR2 mRNA CTD PMID:20371263 tacrolimus hydrate increases expression ISO RGD:1551003 6480464 Tacrolimus results in increased expression of TLR2 mRNA CTD PMID:29362864 terbufos increases methylation ISO RGD:1353654 6480464 terbufos results in increased methylation of TLR2 promoter CTD PMID:22847954 tetrachloromethane increases expression ISO RGD:1551003 6480464 Carbon Tetrachloride results in increased expression of TLR2 mRNA, Carbon Tetrachloride results in increased expression of TLR2 protein CTD PMID:21291945 more ... tetrachloromethane multiple interactions EXP 6480464 Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of TLR2 mRNA], Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of TLR2 protein] CTD PMID:22683883 tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of TLR2 mRNA, Carbon Tetrachloride results in increased expression of TLR2 protein CTD PMID:22683883 tetrachloromethane multiple interactions ISO RGD:1551003 6480464 ferulic acid inhibits the reaction [Carbon Tetrachloride results in increased expression of TLR2 mRNA] more ... CTD PMID:21291945 more ... titanium atom multiple interactions EXP 6480464 [Lipopolysaccharides co-treated with Titanium] results in increased expression of TLR2 mRNA CTD PMID:21308757 titanium dioxide increases expression ISO RGD:1551003 6480464 titanium dioxide results in increased expression of TLR2 mRNA CTD PMID:23409001 more ... titanium dioxide increases expression EXP 6480464 titanium dioxide results in increased expression of TLR2 mRNA CTD PMID:30012374 topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of TLR2 mRNA CTD PMID:25729387 topotecan increases expression EXP 6480464 Topotecan results in increased expression of TLR2 mRNA CTD PMID:25729387 trans-isoeugenol increases expression ISO RGD:1353654 6480464 isoeugenol results in increased expression of TLR2 mRNA CTD PMID:17936526 tributyrin multiple interactions EXP 6480464 tributyrin inhibits the reaction [Lipopolysaccharides results in increased expression of TLR2 mRNA] CTD PMID:21051124 trimellitic anhydride affects expression ISO RGD:1353654 6480464 trimellitic anhydride affects the expression of TLR2 mRNA CTD PMID:19110044 Tungsten carbide multiple interactions ISO RGD:1353654 6480464 [tungsten carbide co-treated with Cobalt] results in decreased expression of TLR2 mRNA CTD PMID:18078969 vinclozolin increases expression EXP 6480464 vinclozolin results in increased expression of TLR2 mRNA CTD PMID:18629315 vitamin D decreases expression ISO RGD:1353654 6480464 Vitamin D results in decreased expression of TLR2 mRNA, Vitamin D results in decreased expression of TLR2 protein CTD PMID:23281135 vitamin D multiple interactions ISO RGD:1551003 6480464 Vitamin D inhibits the reaction [Dust results in increased expression of TLR2 mRNA] CTD PMID:23281135 vorinostat decreases expression ISO RGD:1353654 6480464 Vorinostat results in decreased expression of TLR2 mRNA, Vorinostat results in decreased expression of TLR2 protein CTD PMID:28963909 zinc oxide multiple interactions ISO RGD:1551003 6480464 [Zinc Oxide analog co-treated with OVAL protein] results in increased expression of TLR2 protein, Zinc Oxide analog promotes the reaction [OVAL protein results in increased expression of TLR2 mRNA] CTD PMID:25127755 zinc protoporphyrin multiple interactions EXP 6480464 zinc protoporphyrin promotes the reaction [TLR2 protein binds to MYD88 protein] CTD PMID:25780291
Biological Process cell activation ISO RGD:1353654 1624291 (PMID:15294986) RGD PMID:15294986 cell surface pattern recognition receptor signaling pathway ISO RGD:1551003 1624291 MGI:MGI:2178675 (MGI:MGI:3042099 , PMID:12719478) RGD MGI:MGI:3042099 , PMID:12719478 cellular response to bacterial lipopeptide ISO RGD:1551003 1624291 MGI:MGI:2674036 (MGI:MGI:3528769 , PMID:15690042) RGD MGI:MGI:3528769 , PMID:15690042 cellular response to diacyl bacterial lipopeptide ISO RGD:1353654 1624291 (PMID:16880211), (PMID:19931471) RGD PMID:16880211 , PMID:19931471 cellular response to diacyl bacterial lipopeptide IEA UniProtKB:O60603 , ensembl:ENSP000002600101600115 GO_REF:0000107 Ensembl GO_REF:0000107 cellular response to interferon-gamma IEA UniProtKB:O60603 , ensembl:ENSP000002600101600115 GO_REF:0000107 Ensembl GO_REF:0000107 cellular response to interferon-gamma ISO RGD:1353654 1624291 (PMID:11672593) RGD PMID:11672593 cellular response to lipoteichoic acid ISO RGD:1551003 1624291 MGI:MGI:2674036 (MGI:MGI:3528769 , PMID:15690042) RGD MGI:MGI:3528769 , PMID:15690042 cellular response to lipoteichoic acid IEA UniProtKB:O60603 , ensembl:ENSP000002600101600115 GO_REF:0000107 Ensembl GO_REF:0000107 cellular response to lipoteichoic acid ISO RGD:1353654 1624291 (PMID:12594207), (PMID:26649771) RGD PMID:12594207 , PMID:26649771 cellular response to peptidoglycan ISO RGD:1551003 1624291 (MGI:MGI:3686795, PMID:16949315) RGD MGI:MGI:3686795 , PMID:16949315 cellular response to triacyl bacterial lipopeptide ISO RGD:1353654 1624291 (PMID:16880211), (PMID:19931471) RGD PMID:16880211 , PMID:19931471 cellular response to triacyl bacterial lipopeptide IEA UniProtKB:O60603 , ensembl:ENSP000002600101600115 GO_REF:0000107 Ensembl GO_REF:0000107 central nervous system myelin formation IDA 7241097 RGD cytokine secretion involved in immune response ISO RGD:1353654 1624291 (PMID:20441518) RGD PMID:20441518 cytokine secretion involved in immune response IEA UniProtKB:O60603 , ensembl:ENSP000002600101600115 GO_REF:0000107 Ensembl GO_REF:0000107 defense response ISO RGD:1551003 1624291 MGI:MGI:2178675 (MGI:MGI:3526877 , PMID:12091878) RGD MGI:MGI:3526877 , PMID:12091878 defense response to Gram-positive bacterium ISO RGD:1353654 1624291 (PMID:11521063) RGD PMID:11521063 defense response to Gram-positive bacterium IEA UniProtKB:O60603 , ensembl:ENSP000002600101600115 GO_REF:0000107 Ensembl GO_REF:0000107 defense response to Gram-positive bacterium ISO RGD:1551003 1624291 MGI:MGI:2178675 more ... RGD MGI:MGI:3528769 more ... detection of diacyl bacterial lipopeptide ISO RGD:1353654 1624291 (PMID:19931471) RGD PMID:19931471 detection of diacyl bacterial lipopeptide IEA UniProtKB:O60603 , ensembl:ENSP000002600101600115 GO_REF:0000107 Ensembl GO_REF:0000107 detection of triacyl bacterial lipopeptide ISO RGD:1353654 1624291 (PMID:19931471) RGD PMID:19931471 detection of triacyl bacterial lipopeptide IEA UniProtKB:O60603 , ensembl:ENSP000002600101600115 GO_REF:0000107 Ensembl GO_REF:0000107 I-kappaB phosphorylation ISO RGD:1353654 1624291 (PMID:19740627) RGD PMID:19740627 I-kappaB phosphorylation IEA UniProtKB:O60603 , ensembl:ENSP000002600101600115 GO_REF:0000107 Ensembl GO_REF:0000107 immune response NAS 1302750 RGD induction by symbiont of defense-related host nitric oxide production ISO RGD:1551003 1624291 MGI:MGI:2178675 (MGI:MGI:3611539 , PMID:16239543) RGD MGI:MGI:3611539 , PMID:16239543 inflammatory response IDA 4889539 RGD inflammatory response IBA PANTHER:PTN000687652 more ... 13792537 PMID:21873635 GO_Central interleukin-10 production ISO RGD:1353654 1624291 (PMID:23826189) RGD PMID:23826189 interleukin-10 production IEA UniProtKB:O60603 , ensembl:ENSP000002600101600115 GO_REF:0000107 Ensembl GO_REF:0000107 learning ISO RGD:1551003 1624291 UniProtKB:P05067 more ... RGD MGI:MGI:5307186 , PMID:22198949 leukotriene metabolic process IDA 7241098 RGD microglia development ISO RGD:1551003 1624291 UniProtKB:P05067 more ... RGD MGI:MGI:5307186 , PMID:22198949 microglial cell activation IDA 1643119 RGD MyD88-dependent toll-like receptor signaling pathway ISO RGD:1551003 1624291 MGI:MGI:108005 (MGI:MGI:3042099 , PMID:12719478) RGD MGI:MGI:3042099 , PMID:12719478 MyD88-dependent toll-like receptor signaling pathway IEA InterPro:IPR027185 1600115 GO_REF:0000002 InterPro GO_REF:0000002 negative regulation of actin filament polymerization ISO RGD:1551003 1624291 ComplexPortal:CPX-1134 (MGI:MGI:5307186, PMID:22198949) RGD MGI:MGI:5307186 , PMID:22198949 negative regulation of cell population proliferation IDA 7241097 RGD negative regulation of interleukin-12 production ISO RGD:1551003 1624291 (MGI:MGI:3686795, PMID:16949315) RGD MGI:MGI:3686795 , PMID:16949315 negative regulation of interleukin-17 production ISO RGD:1551003 1624291 MGI:MGI:2178675 (MGI:MGI:3611539 , PMID:16239543) RGD MGI:MGI:3611539 , PMID:16239543 negative regulation of phagocytosis ISO RGD:1551003 1624291 UniProtKB:P05067 more ... RGD MGI:MGI:5307186 , PMID:22198949 negative regulation of synapse assembly ISO RGD:1551003 1624291 UniProtKB:P05067 more ... RGD MGI:MGI:5307186 , PMID:22198949 nitric oxide metabolic process IDA 1643119 RGD positive regulation of cellular response to macrophage colony-stimulating factor stimulus IEA UniProtKB:O60603 , ensembl:ENSP000002600101600115 GO_REF:0000107 Ensembl GO_REF:0000107 positive regulation of cellular response to macrophage colony-stimulating factor stimulus ISO RGD:1353654 1624291 (PMID:11672593) RGD PMID:11672593 positive regulation of chemokine production ISO RGD:1551003 1624291 MGI:MGI:2178675 (MGI:MGI:3611539 , PMID:16239543) RGD MGI:MGI:3611539 , PMID:16239543 positive regulation of chemokine production IEA UniProtKB:O60603 , ensembl:ENSP000002600101600115 GO_REF:0000107 Ensembl GO_REF:0000107 positive regulation of chemokine production ISO RGD:1353654 1624291 (PMID:19740627) RGD PMID:19740627 positive regulation of cytokine secretion ISO RGD:1551003 1624291 MGI:MGI:2157947 (MGI:MGI:4365650 , PMID:19770268) RGD MGI:MGI:4365650 , PMID:19770268 positive regulation of ERK1 and ERK2 cascade ISO RGD:1551003 1624291 MGI:MGI:2674036 (MGI:MGI:5299952 , PMID:22033934) RGD MGI:MGI:5299952 , PMID:22033934 positive regulation of gene expression ISO RGD:1353654 1624291 (PMID:23817958), (PMID:26649771) RGD PMID:23817958 , PMID:26649771 positive regulation of gene expression IEA UniProtKB:O60603 , ensembl:ENSP000002600101600115 GO_REF:0000107 Ensembl GO_REF:0000107 positive regulation of inflammatory response IEA UniProtKB:O60603 , ensembl:ENSP000002600101600115 GO_REF:0000107 Ensembl GO_REF:0000107 positive regulation of inflammatory response ISO RGD:1353654 1624291 RNAcentral:URS000006FDD4_9606 (PMID:28078022) RGD PMID:28078022 positive regulation of inflammatory response ISO RGD:1551003 1624291 ComplexPortal:CPX-1134 (MGI:MGI:5307186, PMID:22198949) RGD MGI:MGI:5307186 , PMID:22198949 positive regulation of interferon-beta production ISO RGD:1551003 1624291 (MGI:MGI:4456948, PMID:15356140) RGD MGI:MGI:4456948 , PMID:15356140 positive regulation of interleukin-1 beta secretion ISO RGD:1551003 1624291 ComplexPortal:CPX-1134 (MGI:MGI:5307186, PMID:22198949) RGD MGI:MGI:5307186 , PMID:22198949 positive regulation of interleukin-10 production IDA 7241093 RGD positive regulation of interleukin-12 production ISO RGD:1551003 1624291 (MGI:MGI:4456948, PMID:15356140) RGD MGI:MGI:4456948 , PMID:15356140 positive regulation of interleukin-18 production ISO RGD:1551003 1624291 (MGI:MGI:4456948, PMID:15356140) RGD MGI:MGI:4456948 , PMID:15356140 positive regulation of interleukin-6 production ISO RGD:1353654 1624291 (PMID:19740627) RGD PMID:19740627 positive regulation of interleukin-6 production ISO RGD:1551003 1624291 MGI:MGI:2178675 (MGI:MGI:2178646 more ... RGD MGI:MGI:2178646 more ... positive regulation of interleukin-6 secretion ISO RGD:1353654 1624291 RNAcentral:URS000006FDD4_9606 (PMID:28078022) RGD PMID:28078022 positive regulation of interleukin-6 secretion IEA UniProtKB:O60603 , ensembl:ENSP000002600101600115 GO_REF:0000107 Ensembl GO_REF:0000107 positive regulation of interleukin-8 production ISO RGD:1353654 1624291 (PMID:17128265), (PMID:19740627) RGD PMID:17128265 , PMID:19740627 positive regulation of interleukin-8 secretion ISO RGD:1353654 1624291 ComplexPortal:CPX-1134 (PMID:22198949) RGD PMID:22198949 positive regulation of interleukin-8 secretion IEA UniProtKB:O60603 , ensembl:ENSP000002600101600115 GO_REF:0000107 Ensembl GO_REF:0000107 positive regulation of leukocyte migration ISO RGD:1551003 1624291 MGI:MGI:2674036 (MGI:MGI:3814295 , PMID:17114491) RGD MGI:MGI:3814295 , PMID:17114491 positive regulation of macrophage cytokine production ISO RGD:1551003 1624291 MGI:MGI:2178675 (MGI:MGI:2178646 , PMID:10549626) RGD MGI:MGI:2178646 , PMID:10549626 positive regulation of matrix metallopeptidase secretion IEA UniProtKB:O60603 , ensembl:ENSP000002600101600115 GO_REF:0000107 Ensembl GO_REF:0000107 positive regulation of matrix metallopeptidase secretion ISO RGD:1353654 1624291 RNAcentral:URS000006FDD4_9606 (PMID:28078022) RGD PMID:28078022 positive regulation of NF-kappaB transcription factor activity ISO RGD:1353654 1624291 (PMID:12594207), (PMID:21618349) RGD PMID:12594207 , PMID:21618349 positive regulation of NF-kappaB transcription factor activity IEA UniProtKB:O60603 , ensembl:ENSP000002600101600115 GO_REF:0000107 Ensembl GO_REF:0000107 positive regulation of NIK/NF-kappaB signaling ISO RGD:1551003 1624291 MGI:MGI:2674036 (MGI:MGI:5299952 , PMID:22033934) RGD MGI:MGI:5299952 , PMID:22033934 positive regulation of NIK/NF-kappaB signaling IEA UniProtKB:O60603 , ensembl:ENSP000002600101600115 GO_REF:0000107 Ensembl GO_REF:0000107 positive regulation of NIK/NF-kappaB signaling ISO RGD:1353654 1624291 (PMID:19740627) RGD PMID:19740627 positive regulation of nitric oxide biosynthetic process ISO RGD:1551003 1624291 MGI:MGI:2178675 (MGI:MGI:2178646 more ... RGD MGI:MGI:2178646 more ... positive regulation of nitric-oxide synthase biosynthetic process ISO RGD:1551003 1624291 (MGI:MGI:4456948, PMID:15356140) RGD MGI:MGI:4456948 , PMID:15356140 positive regulation of oligodendrocyte differentiation IDA 7241097 RGD positive regulation of toll-like receptor signaling pathway ISO RGD:1353654 1624291 (PMID:17128265) RGD PMID:17128265 positive regulation of toll-like receptor signaling pathway IEA UniProtKB:O60603 , ensembl:ENSP000002600101600115 GO_REF:0000107 Ensembl GO_REF:0000107 positive regulation of transcription by RNA polymerase II ISO RGD:1551003 1624291 (MGI:MGI:4456948, PMID:15356140) RGD MGI:MGI:4456948 , PMID:15356140 positive regulation of tumor necrosis factor biosynthetic process ISO RGD:1551003 1624291 MGI:MGI:2178675 (MGI:MGI:3611539 , PMID:16239543) RGD MGI:MGI:3611539 , PMID:16239543 positive regulation of tumor necrosis factor production ISO RGD:1551003 1624291 MGI:MGI:2178675 more ... RGD MGI:MGI:2178646 more ... positive regulation of tumor necrosis factor secretion ISO RGD:1551003 1624291 ComplexPortal:CPX-1134 (MGI:MGI:5307186, PMID:22198949) RGD MGI:MGI:5307186 , PMID:22198949 positive regulation of Wnt signaling pathway ISO RGD:1353654 1624291 (PMID:16601243) RGD PMID:16601243 positive regulation of Wnt signaling pathway IEA UniProtKB:O60603 , ensembl:ENSP000002600101600115 GO_REF:0000107 Ensembl GO_REF:0000107 positive regulation of xenophagy ISO RGD:1551003 1624291 MGI:MGI:2674036 (MGI:MGI:5299952 , PMID:22033934) RGD MGI:MGI:5299952 , PMID:22033934 regulation of dendritic cell cytokine production ISO RGD:1551003 1624291 (MGI:MGI:3828894, PMID:19047410) RGD MGI:MGI:3828894 , PMID:19047410 response to bacterial lipoprotein IDA 1643119 Pam3CSK4 - a synthetic tripalmitoylated lipopeptide that mimicks the acylated amino terminus of bacterial LPs RGD response to bacterium ISO RGD:1551003 1624291 MGI:MGI:2674036 (MGI:MGI:3814295 , PMID:17114491) RGD MGI:MGI:3814295 , PMID:17114491 response to fatty acid IDA 2312510 RGD response to hypoxia IEP 2312731 RGD response to insulin IEP 2312491 RGD response to lipopolysaccharide IEP 2312734 RGD response to molecule of fungal origin ISO RGD:1551003 1624291 MGI:MGI:2178675 (MGI:MGI:3042099 , PMID:12719478) RGD MGI:MGI:3042099 , PMID:12719478 response to peptidoglycan ISO RGD:1551003 1624291 MGI:MGI:2178675 more ... RGD MGI:MGI:2178646 more ... response to progesterone IEP 2312713 RGD response to toxic substance IEP 2312731 RGD toll-like receptor 2 signaling pathway IEA InterPro:IPR027185 1600115 GO_REF:0000002 InterPro GO_REF:0000002 toll-like receptor signaling pathway IDA 1643119 RGD toll-like receptor signaling pathway IBA PANTHER:PTN000687652 more ... 13792537 PMID:21873635 GO_Central toll-like receptor signaling pathway IMP 5684896 RGD tumor necrosis factor production ISO RGD:1551003 1624291 UniProtKB:P05067 more ... RGD MGI:MGI:5307186 , PMID:22198949 Cellular Component cell body IDA 7241097 RGD cell projection IDA 7241097 RGD cell surface ISO RGD:1353654 1624291 (PMID:12443841) RGD PMID:12443841 cell surface IDA 7241098 RGD cytoplasm ISO RGD:1353654 1624291 (PMID:19740627) RGD PMID:19740627 external side of plasma membrane ISO RGD:1551003 1624291 (MGI:MGI:3050756, PMID:15220916) RGD MGI:MGI:3050756 , PMID:15220916 Golgi apparatus ISO RGD:1353654 1624291 (PMID:16880211) RGD PMID:16880211 Golgi apparatus IEA UniProtKB:O60603 , ensembl:ENSP000002600101600115 GO_REF:0000107 Ensembl GO_REF:0000107 integral component of plasma membrane IBA PANTHER:PTN000687652 , UniProtKB:O00206 13792537 PMID:21873635 GO_Central integral component of plasma membrane ISO RGD:1353654 1624291 (PMID:19509287) RGD PMID:19509287 intrinsic component of plasma membrane ISO RGD:1353654 1624291 (PMID:11274165) RGD PMID:11274165 intrinsic component of plasma membrane IBA PANTHER:PTN000687557 , UniProtKB:O60603 13792537 PMID:21873635 GO_Central membrane raft ISO RGD:1353654 1624291 (PMID:16880211) RGD PMID:16880211 membrane raft IEA UniProtKB:O60603 , ensembl:ENSP000002600101600115 GO_REF:0000107 Ensembl GO_REF:0000107 plasma membrane ISO RGD:1551003 1624291 (MGI:MGI:3042099, PMID:12719478) RGD MGI:MGI:3042099 , PMID:12719478 plasma membrane ISO RGD:1353654 1624291 (PMID:19740627) RGD PMID:19740627 Toll-like receptor 1-Toll-like receptor 2 protein complex ISO RGD:1353654 1624291 (PMID:17889651) RGD PMID:17889651 Toll-like receptor 1-Toll-like receptor 2 protein complex IEA UniProtKB:O60603 , ensembl:ENSP000002600101600115 GO_REF:0000107 Ensembl GO_REF:0000107 Toll-like receptor 2-Toll-like receptor 6 protein complex ISO RGD:1551003 1624291 UniProtKB:Q9EPW9 (MGI:MGI:4419037 , PMID:19931471) RGD MGI:MGI:4419037 , PMID:19931471 Molecular Function amyloid-beta binding IEA UniProtKB:O60603 , ensembl:ENSP000002600101600115 GO_REF:0000107 Ensembl GO_REF:0000107 amyloid-beta binding ISO RGD:1353654 1624291 (PMID:22198949) RGD PMID:22198949 amyloid-beta binding ISO RGD:1551003 1624291 (MGI:MGI:5307186, PMID:22198949) RGD MGI:MGI:5307186 , PMID:22198949 diacyl lipopeptide binding ISO RGD:1551003 1624291 (MGI:MGI:4419037 more ... RGD MGI:MGI:4419037 more ... identical protein binding IEA UniProtKB:O60603 , ensembl:ENSP000002600101600115 GO_REF:0000107 Ensembl GO_REF:0000107 identical protein binding ISO RGD:1353654 1624291 UniProtKB:O60603 (PMID:23155421) RGD PMID:23155421 lipopeptide binding IMP 5684896 RGD lipopolysaccharide binding ISO RGD:1353654 1624291 (PMID:11274165) RGD PMID:11274165 lipopolysaccharide binding IEA UniProtKB:O60603 , ensembl:ENSP000002600101600115 GO_REF:0000107 Ensembl GO_REF:0000107 lipoteichoic acid binding ISO RGD:1551003 1624291 (MGI:MGI:4419037, PMID:19931471) RGD MGI:MGI:4419037 , PMID:19931471 peptidoglycan binding ISO RGD:1353654 1624291 (PMID:11986301) RGD PMID:11986301 peptidoglycan binding IEA UniProtKB:O60603 , ensembl:ENSP000002600101600115 GO_REF:0000107 Ensembl GO_REF:0000107 protein binding IPI RGD:735043 2312510 RGD protein binding ISO RGD:1551003 1624291 UniProtKB:P22366 more ... RGD MGI:MGI:3639312 more ... protein binding ISO RGD:1353654 1624291 UniProtKB:C3PTT6 more ... RGD PMID:10854325 more ... protein heterodimerization activity ISO RGD:1353654 1624291 (PMID:17889651) RGD PMID:17889651 protein heterodimerization activity IEA UniProtKB:O60603 , ensembl:ENSP000002600101600115 GO_REF:0000107 Ensembl GO_REF:0000107 protein heterodimerization activity ISO RGD:1551003 1624291 UniProtKB:Q9EPW9 (MGI:MGI:4419037 , PMID:19931471) RGD MGI:MGI:4419037 , PMID:19931471 protein-containing complex binding ISO RGD:1353654 1624291 ComplexPortal:CPX-1134 (PMID:22198949) RGD PMID:22198949 protein-containing complex binding IEA UniProtKB:O60603 , ensembl:ENSP000002600101600115 GO_REF:0000107 Ensembl GO_REF:0000107 protein-containing complex binding ISO RGD:1551003 1624291 ComplexPortal:CPX-1134 (MGI:MGI:5307186, PMID:22198949) RGD MGI:MGI:5307186 , PMID:22198949 signaling pattern recognition receptor activity ISO RGD:1353654 1624291 (PMID:10384090) RGD PMID:10384090 signaling pattern recognition receptor activity IEA UniProtKB:O60603 , ensembl:ENSP000002600101600115 GO_REF:0000107 Ensembl GO_REF:0000107 signaling receptor activity TAS 1302750 RGD Toll-like receptor binding ISO RGD:1353654 1624291 UniProtKB:Q15399 , UniProtKB:Q9Y2C9 (PMID:16880211) RGD PMID:16880211 Toll-like receptor binding IEA UniProtKB:O60603 , ensembl:ENSP000002600101600115 GO_REF:0000107 Ensembl GO_REF:0000107 triacyl lipopeptide binding ISO RGD:1353654 1624291 (PMID:17889651) RGD PMID:17889651 triacyl lipopeptide binding IEA UniProtKB:O60603 , ensembl:ENSP000002600101600115 GO_REF:0000107 Ensembl GO_REF:0000107 triacyl lipopeptide binding ISO RGD:1551003 1624291 (MGI:MGI:4437881, PMID:17889651) RGD MGI:MGI:4437881 , PMID:17889651
Gene-Chemical Interaction Annotations
