Eno2 (enolase 2) - Rat Genome Database

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Gene: Eno2 (enolase 2) Rattus norvegicus
Analyze
Symbol: Eno2
Name: enolase 2
RGD ID: 2554
Description: Exhibits enzyme binding activity; identical protein binding activity; and phosphopyruvate hydratase activity. Involved in several processes, including glucose metabolic process; negative regulation of neuron death; and response to estradiol. Localizes to several cellular components, including growth cone; membrane raft; and phosphopyruvate hydratase complex. Biomarker of toxic shock syndrome and visual epilepsy. Human ortholog(s) of this gene implicated in prostate cancer. Orthologous to human ENO2 (enolase 2); PARTICIPATES IN gluconeogenesis pathway; glycolysis pathway; glycolysis/gluconeogenesis pathway; INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 2-ethoxyethanol; 2-methoxyethanol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2-phospho-D-glycerate hydro-lyase; Enolase 2 gamma neuronal; enolase 2, gamma; enolase 2, gamma, neuronal; gamma-enolase; gamma-enolase-like; LOC100911625; neural enolase; neuron-specific enolase; NSE; RNEN3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Is Marker For: QTLs:   Coreg2  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Note: LOC100911625 appears to be a duplicate placement of Eno2 (GeneID: 24334) on Rnor_6.0 (Annot. Release 105) that is absent from Rn_Celera and is not supported by syntenic regions in mouse and human. BLAST analysis of the underlying component AABR07066868.1 against the rat genome shows high sequence identity (88% coverage, 99% identity) with part of NC_005103.4 on which Eno2 is annotated. Annotation of Eno2 at this location on Rnor_6.0 is supported by annotation on Rn_Celera and synteny with mouse and human. [14 Apr 2021]
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24157,572,085 - 157,580,971 (-)NCBI
Rnor_6.0 Ensembl4157,285,179 - 157,294,047 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl920,251,521 - 20,260,505 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.04157,285,192 - 157,294,090 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04224,302,788 - 224,311,673 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44160,891,003 - 160,897,723 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14161,135,093 - 161,144,004 (-)NCBI
Celera4146,310,173 - 146,318,990 (-)NCBICelera
Cytogenetic Map4q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane  (EXP)
1,1-dichloroethene  (ISO)
1,10-phenanthroline  (ISO)
1,2-dimethylhydrazine  (ISO)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-ethoxyethanol  (EXP)
2-hydroxypropanoic acid  (ISO)
2-methoxyethanol  (EXP)
3',5'-cyclic AMP  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-dichloroaniline  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methyladenine  (EXP)
3-nitropropanoic acid  (EXP)
4,4'-sulfonyldiphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-azacytidine  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
aluminium atom  (ISO)
aluminium(0)  (ISO)
ammonium chloride  (EXP)
amphetamine  (ISO)
antirheumatic drug  (ISO)
aristolochic acid  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
Azaspiracid  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bleomycin A5  (ISO)
bortezomib  (ISO)
bucladesine  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
cannabidiol  (EXP)
capsaicin  (ISO)
carbon nanotube  (ISO)
cefaloridine  (EXP)
chloroacetaldehyde  (ISO)
chloroquine  (EXP)
chlorpromazine  (EXP)
chromium(6+)  (ISO)
cidofovir anhydrous  (ISO)
cisplatin  (EXP,ISO)
clodronic acid  (ISO)
cobalt atom  (ISO)
cobalt dichloride  (ISO)
cobalt(2+) sulfate  (ISO)
cocaine  (ISO)
cyclosporin A  (ISO)
D-glucose  (ISO)
DAPT  (ISO)
Deguelin  (ISO)
dexamethasone  (ISO)
diethylstilbestrol  (ISO)
dinophysistoxin 1  (ISO)
dioxygen  (ISO)
disulfoton  (EXP)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
estriol  (ISO)
estrone  (ISO)
ethanol  (ISO)
ferric oxide  (ISO)
ferroheme b  (ISO)
folic acid  (ISO)
furan  (EXP)
genistein  (ISO)
glucose  (ISO)
heme b  (ISO)
ifosfamide  (ISO)
indometacin  (ISO)
ketamine  (EXP)
leflunomide  (ISO)
maneb  (ISO)
manganese(II) chloride  (EXP,ISO)
melatonin  (ISO)
metformin  (EXP)
methamphetamine  (EXP)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
methylseleninic acid  (ISO)
mifepristone  (EXP)
N-acetyl-beta-D-glucosamine  (ISO)
N-acetyl-D-glucosamine  (ISO)
N-nitrosodimethylamine  (ISO)
nickel dichloride  (ISO)
nickel sulfate  (ISO)
niclosamide  (ISO)
Nonylphenol  (ISO)
ochratoxin A  (EXP)
paraquat  (EXP,ISO)
PCB138  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenylephrine  (EXP)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
propanal  (ISO)
rac-lactic acid  (ISO)
raloxifene  (ISO)
resorcinol  (ISO)
resveratrol  (EXP,ISO)
Salidroside  (ISO)
sarin  (EXP)
SB 431542  (ISO)
selenium atom  (ISO)
silicon dioxide  (ISO)
sirolimus  (EXP)
sodium arsenate  (ISO)
sodium arsenite  (EXP,ISO)
streptozocin  (ISO)
succimer  (ISO)
sunitinib  (ISO)
tetrachloromethane  (ISO)
thapsigargin  (ISO)
thimerosal  (ISO)
thioacetamide  (EXP)
tremolite asbestos  (ISO)
trichostatin A  (ISO)
Tungsten carbide  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vandetanib  (ISO)
vitamin E  (ISO)
vorinostat  (ISO)
WIN 55212-2  (ISO)
Yessotoxin  (ISO)
zinc dichloride  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
1. Alijo Serrano F, etal., Am J Clin Pathol. 2007 Nov;128(5):733-9.
2. Baydas G, etal., Acta Pharmacol Sin. 2005 Apr;26(4):417-22.
3. Berger RP, etal., Dev Neurosci. 2010;32(5-6):396-405. Epub 2010 Sep 18.
4. Cao F, etal., J Clin Neurosci. 2008 May;15(5):541-4. Epub 2008 Mar 14.
5. Chaves ML, etal., J Neuroinflammation. 2010 Jan 27;7:6.
6. Chuang CK and Liao SK, Chang Gung Med J. 2003 Jan;26(1):26-33.
7. Cid C, etal., Proteomics. 2007 Sep;7(17):3207-18.
8. Diao WF, etal., Neuroscience. 2008 Apr 11;.
9. Ding HY and Gao LX, Zhonghua Bing Li Xue Za Zhi. 2006 Jan;35(1):13-7.
10. Fletcher L, etal., Biochim Biophys Acta. 1976 Nov 8;452(1):245-52.
11. Forss-Petter S, etal., J Neurosci Res 1986;16(1):141-56.
12. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
13. GOA data from the GO Consortium
14. Gonzalez-Quevedo A, etal., Clin Biochem. 2011 Feb;44(2-3):154-9. Epub 2010 Dec 1.
15. Jorgensen OS and Centervall G, J Neurochem. 1982 Aug;39(2):537-42.
16. Ledesma MD, etal., Brain Res. 2003 Oct 10;987(1):107-16.
17. Marangos PJ, etal., J Neurochem. 1979 Jul;33(1):319-29.
18. Mulvany NJ and Allen DG, Int J Gynecol Pathol. 2008 Jan;27(1):49-57.
19. Nakajima K, etal., J Neurochem. 1994 Dec;63(6):2048-57.
20. NCBI rat LocusLink and RefSeq merged data July 26, 2002
21. Obermajer N, etal., Int J Biochem Cell Biol. 2009 Aug-Sep;41(8-9):1685-96. doi: 10.1016/j.biocel.2009.02.019. Epub 2009 Mar 6.
22. Okon K, etal., Pol J Pathol. 2007;58(4):227-33.
23. Ortega HH, etal., Reprod Domest Anim. 2006 Jun;41(3):204-9.
24. Oses JP, etal., Brain Res Bull. 2004 Sep 30;64(3):237-42.
25. Pelinka LE, etal., Shock. 2005 Aug;24(2):119-23.
26. Pipeline to import KEGG annotations from KEGG into RGD
27. Ratnakumari L and Murthy CR, Neurosci Lett. 1993 Oct 14;161(1):37-40.
28. RGD automated data pipeline
29. RGD automated import pipeline for gene-chemical interactions
30. Sakai A, etal., Chem Res Toxicol. 2005 Feb;18(2):277-82.
31. Sakimura K, etal., Proc Natl Acad Sci U S A 1985 Nov;82(21):7453-7.
32. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
33. Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
34. Ueta H, etal., Neurosci Res. 2004 Apr;48(4):379-86.
35. Vakhitova IuV, etal., Mol Biol (Mosk). 2005 Mar-Apr;39(2):276-85.
36. Valastro B, etal., J Neurochem. 2007 Aug;102(4):1395-409. Epub 2007 May 26.
37. Wang P, etal., Zhongguo Dang Dai Er Ke Za Zhi. 2008 Feb;10(1):65-9.
38. Wang Q, etal., Int J Cancer. 2004 Sep 10;111(4):508-13.
39. Yamamoto J, etal., Oncol Rep. 2004 Apr;11(4):825-31.
40. Yamate J, etal., J Comp Pathol. 2007 Jul;137(1):9-21. Epub 2007 May 29.
41. Yang XL, etal., Zhonghua Er Ke Za Zhi. 2006 Aug;44(8):583-6.
42. Yilmaz N, etal., Cell Mol Neurobiol. 2011 May;31(4):579-85. Epub 2011 Feb 4.
43. Zhao YC, etal., Zhonghua Nan Ke Xue. 2007 Feb;13(2):157-60.
Additional References at PubMed
PMID:2450052   PMID:2989793   PMID:7753500   PMID:9364238   PMID:9671661   PMID:9758704   PMID:15489334   PMID:16935281   PMID:17634366   PMID:18523310   PMID:18830828   PMID:20458337  
PMID:20592343   PMID:21416483   PMID:22420779   PMID:22528735   PMID:22664934   PMID:23533145   PMID:24042457   PMID:27291422   PMID:28508170   PMID:29728894  


Genomics

Comparative Map Data
Eno2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24157,572,085 - 157,580,971 (-)NCBI
Rnor_6.0 Ensembl4157,285,179 - 157,294,047 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl920,251,521 - 20,260,505 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.04157,285,192 - 157,294,090 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04224,302,788 - 224,311,673 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44160,891,003 - 160,897,723 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14161,135,093 - 161,144,004 (-)NCBI
Celera4146,310,173 - 146,318,990 (-)NCBICelera
Cytogenetic Map4q42NCBI
ENO2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl126,913,745 - 6,923,698 (+)EnsemblGRCh38hg38GRCh38
GRCh38126,914,580 - 6,923,697 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37127,023,744 - 7,032,860 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36126,893,875 - 6,903,120 (+)NCBINCBI36hg18NCBI36
Build 34126,893,874 - 6,903,120NCBI
Celera128,642,227 - 8,651,475 (+)NCBI
Cytogenetic Map12p13.31NCBI
HuRef126,879,463 - 6,888,873 (+)NCBIHuRef
CHM1_1127,022,496 - 7,031,732 (+)NCBICHM1_1
Eno2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396124,737,016 - 124,746,636 (-)NCBIGRCm39mm39
GRCm39 Ensembl6124,737,016 - 124,746,636 (-)Ensembl
GRCm386124,760,053 - 124,769,673 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6124,760,053 - 124,769,673 (-)EnsemblGRCm38mm10GRCm38
MGSCv376124,710,073 - 124,719,527 (-)NCBIGRCm37mm9NCBIm37
MGSCv366124,725,674 - 124,735,128 (-)NCBImm8
Celera6126,441,787 - 126,451,238 (-)NCBICelera
Cytogenetic Map6F2NCBI
cM Map659.17NCBI
Eno2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554134,498,625 - 4,506,769 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554134,498,625 - 4,506,769 (+)NCBIChiLan1.0ChiLan1.0
ENO2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1126,958,965 - 6,968,342 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl126,958,960 - 6,968,342 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0127,043,807 - 7,053,178 (+)NCBIMhudiblu_PPA_v0panPan3
ENO2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12738,120,404 - 38,128,543 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2738,119,413 - 38,129,182 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha278,488,257 - 8,496,383 (+)NCBI
ROS_Cfam_1.02738,472,946 - 38,481,067 (-)NCBI
UMICH_Zoey_3.12738,347,347 - 38,355,466 (-)NCBI
UNSW_CanFamBas_1.02738,388,323 - 38,396,440 (-)NCBI
UU_Cfam_GSD_1.0277,966,986 - 7,975,105 (+)NCBI
Eno2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945102,237,098 - 102,245,902 (-)NCBI
SpeTri2.0NW_004936709904,647 - 913,445 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ENO2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl563,799,339 - 63,836,688 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1563,799,927 - 63,809,067 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2566,236,691 - 66,245,741 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ENO2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1116,945,243 - 6,954,959 (+)NCBI
ChlSab1.1 Ensembl116,945,413 - 6,957,304 (+)Ensembl
Vero_WHO_p1.0NW_0236660631,262,744 - 1,272,484 (-)NCBI
Eno2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248603,553,936 - 3,561,343 (+)NCBI

Position Markers
D4Wox14  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24157,578,205 - 157,578,332 (+)MAPPER
mRatBN7.24157,578,205 - 157,578,332 (-)MAPPER
Rnor_6.04157,291,311 - 157,291,437NCBIRnor6.0
Rnor_6.0920,254,220 - 20,254,346NCBIRnor6.0
Rnor_5.0919,130,196 - 19,130,322UniSTSRnor5.0
Rnor_5.04224,308,907 - 224,309,033UniSTSRnor5.0
RGSC_v3.44160,896,277 - 160,896,403UniSTSRGSC3.4
RGSC_v3.44160,896,276 - 160,896,403RGDRGSC3.4
RGSC_v3.14161,141,212 - 161,141,339RGD
Celera4146,316,287 - 146,316,413UniSTS
RH 3.4 Map41005.6RGD
RH 3.4 Map41005.6UniSTS
Cytogenetic Map4q42UniSTS
D4Wox15  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24157,578,615 - 157,578,785 (+)MAPPER
mRatBN7.24157,578,615 - 157,578,785 (-)MAPPER
Rnor_6.04157,291,721 - 157,291,890NCBIRnor6.0
Rnor_6.0920,253,767 - 20,253,936NCBIRnor6.0
Rnor_5.0919,129,743 - 19,129,912UniSTSRnor5.0
Rnor_5.04224,309,317 - 224,309,486UniSTSRnor5.0
RGSC_v3.44160,896,687 - 160,896,856UniSTSRGSC3.4
RGSC_v3.44160,896,686 - 160,896,856RGDRGSC3.4
RGSC_v3.14161,141,622 - 161,141,792RGD
Celera4146,316,697 - 146,316,868UniSTS
RH 3.4 Map41005.6RGD
RH 3.4 Map41005.6UniSTS
Cytogenetic Map4q42UniSTS
D4Mit3  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24157,573,398 - 157,573,521 (+)MAPPER
mRatBN7.24157,573,398 - 157,573,521 (-)MAPPER
Rnor_6.0920,259,031 - 20,259,151NCBIRnor6.0
Rnor_6.04157,286,506 - 157,286,626NCBIRnor6.0
Rnor_5.0919,135,007 - 19,135,127UniSTSRnor5.0
Rnor_5.04224,304,102 - 224,304,222UniSTSRnor5.0
RGSC_v3.44160,891,472 - 160,891,592UniSTSRGSC3.4
RGSC_v3.44160,891,471 - 160,891,592RGDRGSC3.4
RGSC_v3.14161,136,407 - 161,136,528RGD
Celera4146,311,488 - 146,311,608UniSTS
Cytogenetic Map4q42UniSTS
D4Mit31  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24108,086,268 - 108,086,390 (+)MAPPER
Rnor_6.04106,590,076 - 106,590,199NCBIRnor6.0
Rnor_5.04171,308,484 - 171,308,607UniSTSRnor5.0
RGSC_v3.44109,466,351 - 109,466,475RGDRGSC3.4
RGSC_v3.44109,466,352 - 109,466,475UniSTSRGSC3.4
RGSC_v3.14109,710,832 - 109,710,956RGD
Celera497,168,055 - 97,168,178UniSTS
Cytogenetic Map4q42UniSTS
D4Got134  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24157,573,397 - 157,573,546 (-)MAPPER
mRatBN7.24157,573,397 - 157,573,546 (+)MAPPER
Rnor_6.0920,259,006 - 20,259,152NCBIRnor6.0
Rnor_6.04157,286,505 - 157,286,651NCBIRnor6.0
Rnor_5.0919,134,982 - 19,135,128UniSTSRnor5.0
Rnor_5.04224,304,101 - 224,304,247UniSTSRnor5.0
RGSC_v3.44160,891,471 - 160,891,617UniSTSRGSC3.4
RGSC_v3.44160,891,470 - 160,891,617RGDRGSC3.4
RGSC_v3.14161,136,406 - 161,136,553RGD
Celera4146,311,487 - 146,311,633UniSTS
RH 3.4 Map41003.0RGD
RH 3.4 Map41003.0UniSTS
Cytogenetic Map4q42UniSTS
D1Mgh30  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24157,578,663 - 157,578,781 (-)MAPPER
mRatBN7.24157,578,663 - 157,578,781 (+)MAPPER
Rnor_6.0920,253,771 - 20,253,888NCBIRnor6.0
Rnor_6.04157,291,769 - 157,291,886NCBIRnor6.0
Rnor_5.0919,129,747 - 19,129,864UniSTSRnor5.0
Rnor_5.04224,309,365 - 224,309,482UniSTSRnor5.0
RGSC_v3.44160,896,735 - 160,896,852UniSTSRGSC3.4
RGSC_v3.44160,895,153 - 160,897,214RGDRGSC3.4
RGSC_v3.14161,141,674 - 161,141,788RGD
Celera4146,316,745 - 146,316,864UniSTS
RH 3.4 Map1735.9RGD
RH 3.4 Map1735.9UniSTS
Cytogenetic Map4q42UniSTS
D4Mit1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24157,578,182 - 157,578,333 (+)MAPPER
mRatBN7.24157,578,182 - 157,578,333 (-)MAPPER
Rnor_6.04157,291,288 - 157,291,438NCBIRnor6.0
Rnor_6.0920,254,219 - 20,254,369NCBIRnor6.0
Rnor_5.0919,130,195 - 19,130,345UniSTSRnor5.0
Rnor_5.04224,308,884 - 224,309,034UniSTSRnor5.0
RGSC_v3.44160,896,254 - 160,896,404UniSTSRGSC3.4
RGSC_v3.44160,896,253 - 160,896,404RGDRGSC3.4
RGSC_v3.14161,141,189 - 161,141,340RGD
Celera4146,316,264 - 146,316,414UniSTS
RH 3.4 Map41005.6RGD
RH 3.4 Map41005.6UniSTS
Cytogenetic Map4q42UniSTS
D4Arb23  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24157,578,142 - 157,578,385 (+)MAPPER
mRatBN7.24157,578,142 - 157,578,385 (-)MAPPER
Rnor_6.0920,254,167 - 20,254,409NCBIRnor6.0
Rnor_6.04157,291,248 - 157,291,490NCBIRnor6.0
Rnor_5.0919,130,143 - 19,130,385UniSTSRnor5.0
Rnor_5.04224,308,844 - 224,309,086UniSTSRnor5.0
RGSC_v3.44160,896,214 - 160,896,456UniSTSRGSC3.4
RGSC_v3.44160,896,213 - 160,896,456RGDRGSC3.4
RGSC_v3.14161,141,149 - 161,141,392RGD
Celera4146,316,224 - 146,316,466UniSTS
RH 2.0 Map4978.5RGD
FHH x ACI Map495.6799RGD
Cytogenetic Map4q42UniSTS
RH129856  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24157,572,122 - 157,572,338 (-)MAPPER
mRatBN7.24157,572,122 - 157,572,338 (+)MAPPER
Rnor_6.04157,285,230 - 157,285,445NCBIRnor6.0
Rnor_6.0920,260,212 - 20,260,427NCBIRnor6.0
Rnor_5.04224,302,826 - 224,303,041UniSTSRnor5.0
Rnor_5.0919,136,188 - 19,136,403UniSTSRnor5.0
RGSC_v3.44160,890,196 - 160,890,411UniSTSRGSC3.4
Celera4146,310,210 - 146,310,425UniSTS
RH 3.4 Map41002.0UniSTS
Cytogenetic Map4q42UniSTS
BE103187  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24157,581,316 - 157,581,494 (-)MAPPER
mRatBN7.24157,581,316 - 157,581,494 (+)MAPPER
Rnor_6.04157,294,418 - 157,294,595NCBIRnor6.0
Rnor_6.0920,251,062 - 20,251,239NCBIRnor6.0
Rnor_5.04224,312,014 - 224,312,191UniSTSRnor5.0
Rnor_5.0919,127,038 - 19,127,215UniSTSRnor5.0
RGSC_v3.44160,899,384 - 160,899,561UniSTSRGSC3.4
Celera4146,319,371 - 146,319,548UniSTS
RH 3.4 Map41010.0UniSTS
Cytogenetic Map4q42UniSTS
UniSTS:142992  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24157,575,427 - 157,575,610 (+)MAPPER
mRatBN7.24157,575,427 - 157,575,610 (-)MAPPER
Rnor_6.04157,288,533 - 157,288,715NCBIRnor6.0
Rnor_6.0920,256,942 - 20,257,124NCBIRnor6.0
Rnor_5.0919,132,918 - 19,133,100UniSTSRnor5.0
Rnor_5.04224,306,129 - 224,306,311UniSTSRnor5.0
RGSC_v3.44160,893,499 - 160,893,681UniSTSRGSC3.4
Celera4146,313,515 - 146,313,697UniSTS
Cytogenetic Map4q42UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61446Coreg2Compensatory renal growth QTL 23.5kidney mass (VT:0002707)compensatory renal growth score (CMO:0001894)4147274055157294090Rat
61451Ciaa4CIA Autoantibody QTL 43.1blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)4125884464168047091Rat
724535Cm18Cardiac mass QTL 182.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)4117926139162926139Rat
724558Plsm2Polydactyly-luxate syndrome (PLS) morphotypes QTL 20.0003hindlimb integrity trait (VT:0010563)hind foot phalanges count (CMO:0001949)4131834282176834282Rat
1331738Bp209Blood pressure QTL 2092.979arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)4136351734180689124Rat
1331759Hrtrt13Heart rate QTL 133.54628heart pumping trait (VT:2000009)heart rate (CMO:0000002)4108876717169215811Rat
737821Hcar9Hepatocarcinoma resistance QTL 93.7liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)4105971071168047091Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)463537179157286626Rat
631683Bp116Blood pressure QTL 1160.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4123111827168111827Rat
737978Pia23Pristane induced arthritis QTL 235.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4131532269168047091Rat
1331802Srn5Serum renin concentration QTL 53.045renin activity (VT:0005581)plasma renin activity level (CMO:0000116)4116726724157291438Rat
1582237Kidm34Kidney mass QTL 3440.0001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)4146942075168998263Rat
1298524Oia8Oil induced arthritis QTL 8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4136351734174694858Rat
631511Pia7Pristane induced arthritis QTL 74.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4131532269168047091Rat
1581574Eae20Experimental allergic encephalomyelitis QTL 207.8nervous system integrity trait (VT:0010566)percentage of study population developing experimental autoimmune encephalomyelitis during a period of time (CMO:0001047)4152482121158564471Rat
2293659Bmd35Bone mineral density QTL 354.50.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)4136908430182878540Rat
634335Anxrr16Anxiety related response QTL 167.22locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)494893247168046938Rat
634342Cia24Collagen induced arthritis QTL 244.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4145373934176509907Rat
634347Hcar8Hepatocarcinoma resistance QTL 85.8liver integrity trait (VT:0010547)liver tumorous lesion area to total liver area ratio (CMO:0001075)4123478354168478354Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)484475257178931073Rat
1578674Bmd12Bone mineral density QTL 123.8femur mineral mass (VT:0010011)cortical volumetric bone mineral density (CMO:0001730)4137171018182171018Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)47850904182171018Rat
1358364Sradr4Stress Responsive Adrenal Weight QTL 44.92adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)4128602727173602727Rat
1358202Gluco11Glucose level QTL 112.40.02adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)486438317168047091Rat
2303623Vencon2Ventilatory control QTL 23.8respiration trait (VT:0001943)minute ventilation (CMO:0000132)4134917642179917642Rat
1549827Scl46Serum cholesterol level QTL 463.5blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)4131864442176864442Rat
61362Oia2Oil induced arthritis QTL 20.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4136351734174694858Rat
61422Cia13Collagen induced arthritis QTL 134.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4132455408168047091Rat
6478718Anxrr34Anxiety related response QTL 340.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4145547014184226339Rat
6478720Alc23Alcohol consumption QTL 230.00509drinking behavior trait (VT:0001422)ethanol drink intake rate to body weight ratio (CMO:0001616)4155386197184226339Rat
6478728Anxrr36Anxiety related response QTL 360.01061locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155386197184226339Rat
6478733Anxrr37Anxiety related response QTL 370.00095locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155386197184226339Rat
6478737Anxrr38Anxiety related response QTL 380.00159locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155386197184226339Rat
6478748Anxrr42Anxiety related response QTL 420.28008locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4145547014184226339Rat
6478754Anxrr43Anxiety related response QTL 430.14035locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4145547014184226339Rat
6478757Anxrr44Anxiety related response QTL 440.01087locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155386197184226339Rat
6478778Anxrr51Anxiety related response QTL 510.25384locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4123587009168587009Rat
6478782Anxrr52Anxiety related response QTL 520.02091locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155386197184226339Rat
6478785Anxrr53Anxiety related response QTL 530.01397locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155386197184226339Rat
6478693Anxrr32Anxiety related response QTL 320.00092locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4145547014184226339Rat
6478700Anxrr33Anxiety related response QTL 330.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4145547014184226339Rat
7411558Bw133Body weight QTL 13313.840.001body mass (VT:0001259)body weight gain (CMO:0000420)4124442168169442168Rat
10053718Scort25Serum corticosterone level QTL 252.150.0097blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)4156855449184226339Rat
10401796Kidm48Kidney mass QTL 48kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)4146497452184226339Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)423850384169318094Rat
12798519Anxrr54Anxiety related response QTL 542.540.05locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4112807675157807675Rat
12798525Anxrr57Anxiety related response QTL 573.210.05locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146086918168047091Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:312
Count of miRNA genes:177
Interacting mature miRNAs:202
Transcripts:ENSRNOT00000005535, ENSRNOT00000005601
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system nervous system renal system reproductive system respiratory system
High
Medium
Low 16
Below cutoff 1 5 3 1 51 3 8 3

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000005535   ⟹   ENSRNOP00000005535
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl920,251,521 - 20,260,505 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000005601   ⟹   ENSRNOP00000005601
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl4157,285,179 - 157,294,047 (-)Ensembl
RefSeq Acc Id: NM_139325   ⟹   NP_647541
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24157,572,085 - 157,580,936 (-)NCBI
Rnor_6.04157,285,193 - 157,294,037 (-)NCBI
Rnor_5.04224,302,788 - 224,311,673 (-)NCBI
RGSC_v3.44160,891,003 - 160,897,723 (-)RGD
Celera4146,310,173 - 146,318,990 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006237330   ⟹   XP_006237392
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24157,572,085 - 157,580,971 (-)NCBI
Rnor_6.04157,285,192 - 157,294,090 (-)NCBI
Rnor_5.04224,302,788 - 224,311,673 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_647541   ⟸   NM_139325
- UniProtKB: P07323 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006237392   ⟸   XM_006237330
- Peptide Label: isoform X1
- UniProtKB: P07323 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000005601   ⟸   ENSRNOT00000005601
RefSeq Acc Id: ENSRNOP00000005535   ⟸   ENSRNOT00000005535

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693387
Promoter ID:EPDNEW_R3912
Type:initiation region
Name:LOC100911625_1
Description:gamma-enolase-like
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04157,294,023 - 157,294,083EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2554 AgrOrtholog
  RGD:6491529 AgrOrtholog
Ensembl Genes ENSRNOG00000013141 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOG00000048365 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSRNOP00000005535 UniProtKB/Swiss-Prot
  ENSRNOP00000005601 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000005535 UniProtKB/Swiss-Prot
  ENSRNOT00000005601 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 3.20.20.120 UniProtKB/Swiss-Prot
  3.30.390.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:6888358 IMAGE-MGC_LOAD
InterPro Enolase UniProtKB/Swiss-Prot
  Enolase-like_C_sf UniProtKB/Swiss-Prot
  Enolase-like_N UniProtKB/Swiss-Prot
  Enolase_C UniProtKB/Swiss-Prot
  Enolase_CS UniProtKB/Swiss-Prot
  Enolase_N UniProtKB/Swiss-Prot
KEGG Report rno:100911625 UniProtKB/Swiss-Prot
  rno:24334 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72663 IMAGE-MGC_LOAD
NCBI Gene 24334 ENTREZGENE
PANTHER PTHR11902 UniProtKB/Swiss-Prot
Pfam Enolase_C UniProtKB/Swiss-Prot
  Enolase_N UniProtKB/Swiss-Prot
PhenoGen Eno2 PhenoGen
PIRSF Enolase UniProtKB/Swiss-Prot
PRINTS ENOLASE UniProtKB/Swiss-Prot
PROSITE ENOLASE UniProtKB/Swiss-Prot
SMART Enolase_C UniProtKB/Swiss-Prot
  Enolase_N UniProtKB/Swiss-Prot
Superfamily-SCOP SSF51604 UniProtKB/Swiss-Prot
  SSF54826 UniProtKB/Swiss-Prot
TIGR TC229025
TIGRFAMs eno UniProtKB/Swiss-Prot
UniProt ENOG_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Eno2  enolase 2  LOC100911625  gamma-enolase-like  Data Merged 737654 PROVISIONAL
2016-05-04 Eno2  enolase 2  Eno2  enolase 2, gamma, neuronal  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-07-05 LOC100911625  gamma-enolase-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-02-15 Eno2  enolase 2, gamma, neuronal  Eno2  enolase 2, gamma  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-12-14 Eno2  enolase 2, gamma    enolase 2, gamma   Symbol and Name status set to approved 1299863 APPROVED
2002-06-10 Eno2  enolase 2, gamma       Name updated 70585 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_function catalyzes the interconversion of 2-phosphoglycerate to phosphoenolpyruvate in the glycolytic pathway