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Gene: Gatad2b (GATA zinc finger domain containing 2B) Rattus norvegicus

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Symbol:

Gatad2b

Name:

GATA zinc finger domain containing 2B

RGD ID:

1308533

Description:

Predicted to enable sequence-specific DNA binding activity and zinc ion binding activity. Predicted to be involved in chromatin remodeling and negative regulation of transcription by RNA polymerase II. Predicted to be located in chromosome, telomeric region and nucleoplasm. Predicted to be part of NuRD complex. Human ortholog(s) of this gene implicated in GAND syndrome. Orthologous to human GATAD2B (GATA zinc finger domain containing 2B); PARTICIPATES IN CHD family mediated chromatin remodeling pathway; INTERACTS WITH acetamide; acrylamide; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC310614; RGD1308533; similar to transcription repressor p66; transcription repressor p66 beta component of the MeCP1 complex; transcriptional repressor p66-beta

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	GATAD2B (GATA zinc finger domain containing 2B)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Gatad2b (GATA zinc finger domain containing 2B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Gatad2b (GATA zinc finger domain containing 2B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	GATAD2B (GATA zinc finger domain containing 2B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	GATAD2B (GATA zinc finger domain containing 2B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Gatad2b (GATA zinc finger domain containing 2B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	GATAD2B (GATA zinc finger domain containing 2B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	GATAD2B (GATA zinc finger domain containing 2B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Gatad2b (GATA zinc finger domain containing 2B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Gatad2b (GATA zinc finger domain containing 2B)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Gatad2b (GATA zinc finger domain containing 2B)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	GATAD2B (GATA zinc finger domain containing 2B)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	GATAD2B (GATA zinc finger domain containing 2B)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	gatad2b (GATA zinc finger domain containing 2B)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	gatad2b (GATA zinc finger domain containing 2B)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	dcp-66	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	simj	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	gatad2b	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	178,046,192 - 178,127,633 (+)	NCBI		GRCr8
GRCr8 Ensembl	2	178,046,085 - 178,147,315 (+)	Ensembl		GRCr8 Ensembl
mRatBN7.2	2	175,748,594 - 175,829,837 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	175,749,433 - 175,825,542 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	182,889,438 - 182,965,027 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	180,911,832 - 180,987,269 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	175,512,135 - 175,587,550 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	189,654,871 - 189,735,056 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	189,655,702 - 189,733,540 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	209,087,998 - 209,165,690 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	182,537,125 - 182,615,717 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	2	169,684,333 - 169,759,364 (+)	NCBI		Celera
RGSC_v3.1	2	182,487,230 - 182,565,822 (+)	NCBI
Cytogenetic Map	2	q34	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autism spectrum disorder (ISO)

dyschromatosis symmetrica hereditaria (ISO)

GAND syndrome (ISO,ISS)

gastrointestinal stromal tumor (ISO)

genetic disease (ISO)

immunodeficiency 42 (ISO)

intellectual disability (ISO)

MHC class II deficiency (ISO)

parathyroid carcinoma (ISO)

Parkinson's disease 2 (ISO)

severe congenital neutropenia 3 (ISO)

severe congenital neutropenia 5 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(S)-nicotine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxynon-2-enal (ISO)

acetamide (EXP)

acrylamide (EXP)

aflatoxin B1 (ISO)

antirheumatic drug (ISO)

aristolochic acid A (ISO)

atrazine (ISO)

benzatropine (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

Brodifacoum (EXP)

cadmium atom (ISO)

cadmium dichloride (ISO)

caffeine (ISO)

cannabidiol (ISO)

carbamazepine (ISO)

chlorpyrifos (ISO)

cisplatin (ISO)

cobalt dichloride (ISO)

Cuprizon (ISO)

DDE (ISO)

dicrotophos (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

enzyme inhibitor (ISO)

epoxiconazole (ISO)

ethanol (ISO)

FR900359 (ISO)

GSK-J4 (ISO)

hydrogen cyanide (ISO)

hydrogen peroxide (ISO)

ivermectin (ISO)

ketamine (EXP)

lead(0) (ISO)

mercury atom (ISO)

mercury(0) (ISO)

methamphetamine (EXP)

methoxychlor (EXP)

methylmercury chloride (ISO)

nicotine (ISO)

paracetamol (EXP,ISO)

paraquat (ISO)

phenobarbital (ISO)

phenylmercury acetate (ISO)

potassium cyanide (ISO)

SB 431542 (ISO)

silver atom (ISO)

silver(0) (ISO)

tetrachloromethane (ISO)

thioacetamide (EXP)

thiram (ISO)

titanium dioxide (ISO)

trichostatin A (ISO)

triphenyl phosphate (ISO)

triptonide (ISO)

troglitazone (ISO)

urethane (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

chromatin remodeling (IEA,ISO)

negative regulation of transcription by RNA polymerase II (IBA,IEA)

regulation of DNA-templated transcription (IEA)

regulation of gene expression (IEA)

Cellular Component

chromosome, telomeric region (IEA,ISO)

nucleoplasm (IEA,ISO)

nucleus (IEA,ISO)

NuRD complex (IBA,IEA,ISO)

Molecular Function

protein binding (ISO)

sequence-specific DNA binding (IEA)

zinc ion binding (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

CHD family mediated chromatin remodeling pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	The nucleosome remodeling and deacetylase complex in development and disease.	Basta J and Rauchman M, Transl Res. 2014 May 10. pii: S1931-5244(14)00166-2. doi: 10.1016/j.trsl.2014.05.003.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
4.	GOA pipeline	RGD automated data pipeline
5.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:16217013	PMID:31505169

Genomics

Comparative Map Data

Gatad2b
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	178,046,192 - 178,127,633 (+)	NCBI		GRCr8
GRCr8 Ensembl	2	178,046,085 - 178,147,315 (+)	Ensembl		GRCr8 Ensembl
mRatBN7.2	2	175,748,594 - 175,829,837 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	175,749,433 - 175,825,542 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	182,889,438 - 182,965,027 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	180,911,832 - 180,987,269 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	175,512,135 - 175,587,550 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	189,654,871 - 189,735,056 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	189,655,702 - 189,733,540 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	209,087,998 - 209,165,690 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	182,537,125 - 182,615,717 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	2	169,684,333 - 169,759,364 (+)	NCBI		Celera
RGSC_v3.1	2	182,487,230 - 182,565,822 (+)	NCBI
Cytogenetic Map	2	q34	NCBI

GATAD2B
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	153,804,725 - 153,922,972 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	153,789,030 - 153,923,360 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	153,777,201 - 153,895,448 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	152,043,825 - 152,162,075 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	1	126,848,798 - 126,967,204 (-)	NCBI		Celera
Cytogenetic Map	1	q21.3	NCBI
HuRef	1	125,139,660 - 125,258,037 (-)	NCBI		HuRef
CHM1_1	1	155,173,146 - 155,291,764 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	152,941,989 - 153,060,229 (-)	NCBI		T2T-CHM13v2.0

Gatad2b
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	90,200,488 - 90,270,712 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	90,200,485 - 90,270,714 (+)	Ensembl		GRCm39 Ensembl
GRCm38	3	90,293,181 - 90,363,405 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	90,293,178 - 90,363,407 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	3	90,145,576 - 90,162,042 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	3	90,427,581 - 90,444,047 (+)	NCBI		MGSCv36	mm8
Celera	3	90,379,290 - 90,395,690 (+)	NCBI		Celera
Cytogenetic Map	3	F1	NCBI
cM Map	3	39.21	NCBI

Gatad2b
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955545	430,245 - 517,790 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955545	424,997 - 519,031 (-)	NCBI	ChiLan1.0	ChiLan1.0

GATAD2B
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	95,907,189 - 96,027,933 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	95,642,428 - 95,763,170 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	129,161,151 - 129,279,702 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	132,794,458 - 132,907,674 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	132,794,458 - 132,813,108 (-)	Ensembl	panpan1.1		panPan2

GATAD2B
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	43,201,307 - 43,295,868 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	7	43,254,305 - 43,294,211 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	42,691,099 - 42,787,860 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	43,071,124 - 43,167,834 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	7	43,071,517 - 43,166,099 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	7	42,849,795 - 42,946,193 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	42,903,094 - 42,999,568 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	43,187,301 - 43,283,284 (+)	NCBI		UU_Cfam_GSD_1.0

Gatad2b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	24,548,713 - 24,567,772 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936580	3,579,119 - 3,597,667 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936580	3,579,119 - 3,597,644 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GATAD2B
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	95,766,490 - 95,864,435 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	95,766,989 - 95,864,502 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	104,747,140 - 104,764,791 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

GATAD2B
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	9,888,586 - 10,003,215 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	9,888,705 - 10,000,099 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	9,258,704 - 9,378,252 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Gatad2b
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624885	3,362,823 - 3,375,179 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624885	3,297,191 - 3,375,908 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Gatad2b
869 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	60
Count of miRNA genes:	46
Interacting mature miRNAs:	54
Transcripts:	ENSRNOT00000021502
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1358356	Srcrt1	Stress Responsive Cort QTL1	3.66		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	2	163997722	225110681	Rat
1578648	Bss11	Bone structure and strength QTL 11	4.7		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	2	169358774	214358774	Rat
1331734	Bp204	Blood pressure QTL 204	3.61192		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	170656145	239614549	Rat
631566	Bp90	Blood pressure QTL 90		0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	149957381	221199885	Rat
1298074	Bp164	Blood pressure QTL 164		0.003	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	44537979	205135428	Rat
1354648	Bp239	Blood pressure QTL 239		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	67845370	229470703	Rat
1354649	Kidm17	Kidney mass QTL 17	2.9		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	2	83465462	229820014	Rat
1298076	Bp166	Blood pressure QTL 166		0.0009	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	138595962	205135428	Rat
1581576	Pur7	Proteinuria QTL 7		0.0001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	2	80396178	220931218	Rat
61457	Niddm8	Non-insulin dependent diabetes mellitus QTL 8	4.1	0.01	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	2	176840779	178247591	Rat
1581578	Cm49	Cardiac mass QTL 49	4.9	0.01	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	2	145807215	220931416	Rat
631198	Cm22	Cardiac mass QTL 22	4.3	0.0008	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	2	78269809	208420281	Rat
1554319	Bmd2	Bone mineral density QTL 2	13.4	0.0001	lumbar vertebra area (VT:0010570)	lumbar vertebra cross-sectional area (CMO:0001689)	2	122597372	215234002	Rat
12879836	Kidm61	Kidney mass QTL 61		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	154723085	199723085	Rat
1581569	Uae32	Urinary albumin excretion QTL 32		0.0001	urine protein amount (VT:0005160)	urine albumin excretion rate (CMO:0000757)	2	80396178	220931218	Rat
10043136	Iddm54	Insulin dependent diabetes mellitus QTL 54	3.4	0.0001	blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	2	145807215	190807215	Rat
12879837	Am2	Aortic mass QTL 2		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	2	154723085	199723085	Rat
10043139	Iddm55	Insulin dependent diabetes mellitus QTL 55	3.1	0.0001	blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	2	150313808	195313808	Rat
12879838	Cm86	Cardiac mass QTL 86		0.002	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	2	154723085	199723085	Rat
1302793	Bw16	Body weight QTL 16	5	0.0001	body mass (VT:0001259)	body weight (CMO:0000012)	2	159440891	205135267	Rat
12879839	Cm85	Cardiac mass QTL 85		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	2	154723085	199723085	Rat
1549833	Bp257	Blood pressure QTL 257		0.003	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	170652929	215652929	Rat
1358900	Bw48	Body weight QTL 48	4.88		body mass (VT:0001259)	body weight (CMO:0000012)	2	159440891	220931218	Rat
4889834	Pur24	Proteinuria QTL 24	5.8	0.014	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	2	171994826	205135428	Rat
12879845	Cm89	Cardiac mass QTL 89		0.008	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	2	154723085	178247591	Rat
61473	Bp19	Blood pressure QTL 19	6.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	175008837	178247591	Rat
1359030	Bp277	Blood pressure QTL 277			arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	143565208	188565208	Rat
12879846	Cm90	Cardiac mass QTL 90		0.011	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	2	154723085	178247591	Rat
12879847	Am4	Aortic mass QTL 4		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	2	154723085	178247591	Rat
1331760	Bp206	Blood pressure QTL 206	3.62454		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	4265106	205135428	Rat
12879840	Bw179	Body weight QTL 179		0.005	body mass (VT:0001259)	body weight (CMO:0000012)	2	154723085	199723085	Rat
1581502	Esta3	Estrogen-induced thymic atrophy QTL 3			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	2	139067258	192287892	Rat
1359032	Hrtrt18	Heart rate QTL 18			heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	2	159440760	195313808	Rat
2301966	Bp322	Blood pressure QTL 322	3.58		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	144882354	205135428	Rat
1298080	Bp163	Blood pressure QTL 163		0.02	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	67845182	205135428	Rat
1357991	Ael2	Aortic elastin QTL 2	4.2	0.000071	aorta elastin amount (VT:0003905)	aortic elastin	2	169227906	214227906	Rat
8662832	Vetf7	Vascular elastic tissue fragility QTL 7	3.5		aorta elastin amount (VT:0003905)	aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)	2	83400752	223709938	Rat
1298085	Bp165	Blood pressure QTL 165		0.0006	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	44537979	205135428	Rat
1578671	Bmd10	Bone mineral density QTL 10	5.4		femur mineral mass (VT:0010011)	compact volumetric bone mineral density (CMO:0001730)	2	175931416	220931416	Rat
1359022	Ppulsi1	Prepulse inhibition QTL 1	3.63		prepulse inhibition trait (VT:0003088)	acoustic startle response measurement (CMO:0001519)	2	139067258	184067258	Rat
1641891	Alcrsp17	Alcohol response QTL 17			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	2	151869660	251712708	Rat
724534	Uae6	Urinary albumin excretion QTL 6	10		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	2	80396034	220931416	Rat
61374	Edpm2	Estrogen-dependent pituitary mass QTL 2	4.42	0.86	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	2	78269809	205135428	Rat
8662843	Vetf9	Vascular elastic tissue fragility QTL 9	2.05		thoracic aorta molecular composition trait (VT:0010568)	aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)	2	159440760	228950743	Rat
2301415	Cm67	Cardiac mass QTL 67		0.003	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	2	154723085	178247591	Rat
1331794	Bp202	Blood pressure QTL 202	3.66819		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	143344967	251712708	Rat
71113	Cari2	Carrageenan-induced inflammation QTL 2	2.7	0.009	hypodermis integrity trait (VT:0010550)	inflammatory exudate volume (CMO:0001429)	2	143746578	205135428	Rat
1331805	Cm29	Cardiac mass QTL 29	3.50746		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	2	143344967	251712708	Rat
11565180	Kidm56	Kidney mass QTL 56		0.003	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	154723085	178247591	Rat
634308	Sach6	Saccharin preference QTL 6	4.9		taste sensitivity trait (VT:0001986)	saccharin intake volume to total fluid intake volume ratio (CMO:0001601)	2	114384617	215381366	Rat
1598805	Memor8	Memory QTL 8	3		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	2	150096616	195096616	Rat
11565181	Bw176	Body weight QTL 176		0.002	body mass (VT:0001259)	body weight (CMO:0000012)	2	154723085	178247591	Rat
1358917	Cm42	Cardiac mass QTL 42	2.82		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	27148328	206613235	Rat
724568	Uae13	Urinary albumin excretion QTL 13	4.4		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	2	145306936	212705578	Rat
1358913	Cm41	Cardiac mass QTL 41	2.73		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	27148328	206613235	Rat
1300165	Rf9	Renal function QTL 9	3.28		kidney glomerulus integrity trait (VT:0010546)	index of glomerular damage (CMO:0001135)	2	113746222	205135428	Rat
61401	Niddm2	Non-insulin dependent diabetes mellitus QTL 2	4.54		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	2	147287892	192287892	Rat
631507	Bp105	Blood pressure QTL 105		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	114384617	215381366	Rat
1641925	Alcrsp2	Alcohol response QTL 2			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	2	151869660	223841096	Rat
1354609	Niddm62	Non-insulin dependent diabetes mellitus QTL 62	4.72	0.000006	insulin secretion trait (VT:0003564)	plasma insulin level (CMO:0000342)	2	117415288	205135428	Rat
1598833	Bp295	Blood pressure QTL 295	3.5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	150096616	195096616	Rat
1354622	Kidm16	Kidney mass QTL 16	3		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	2	83465462	225110681	Rat
631266	Bp132	Blood pressure QTL 132		0.0005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	47856345	205135428	Rat
631522	Bp74	Blood pressure QTL 74		0.05	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	175008837	220008837	Rat
7488927	Bp365	Blood pressure QTL 365		0.008	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	165453811	210453811	Rat
7488925	Bp364	Blood pressure QTL 364		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	163253030	208253030	Rat
2293843	Kiddil6	Kidney dilation QTL 6	3.1		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	2	44537979	184731399	Rat
2306901	Bp337	Blood pressure QTL 337		0.01	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	166372086	229820014	Rat
1354605	Rf48	Renal function QTL 48	2.9		blood creatinine amount (VT:0005328)	plasma creatinine level (CMO:0000537)	2	76328396	209350714	Rat
7488904	Bp363	Blood pressure QTL 363		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	175279960	178247591	Rat

Markers in Region

RH144504

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	175,787,369 - 175,787,485 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	190,212,260 - 190,212,375	NCBI	Rnor6.0
Rnor_6.0	2	189,695,514 - 189,695,629	NCBI	Rnor6.0
Rnor_5.0	2	209,646,342 - 209,646,457	UniSTS	Rnor5.0
Rnor_5.0	2	209,126,535 - 209,126,650	UniSTS	Rnor5.0
RGSC_v3.4	2	182,576,368 - 182,576,483	UniSTS	RGSC3.4
Celera	2	169,721,844 - 169,721,959	UniSTS
RH 3.4 Map	2	1151.11	UniSTS
Cytogenetic Map	2	q34	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001024888	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008761144	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008761145	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039102301	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039102302	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281823	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281824	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC097428	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473976	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000021502 ⟹ ENSRNOP00000021502

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	178,046,085 - 178,147,315 (+)	Ensembl
mRatBN7.2 Ensembl	2	175,749,433 - 175,825,044 (+)	Ensembl
Rnor_6.0 Ensembl	2	189,655,702 - 189,732,559 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000086285 ⟹ ENSRNOP00000071152

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	178,046,085 - 178,122,383 (+)	Ensembl
mRatBN7.2 Ensembl	2	175,749,433 - 175,825,542 (+)	Ensembl
Rnor_6.0 Ensembl	2	189,714,754 - 189,733,540 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000117370 ⟹ ENSRNOP00000091300

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	178,046,119 - 178,125,902 (+)	Ensembl
mRatBN7.2 Ensembl	2	175,791,055 - 175,825,044 (+)	Ensembl

RefSeq Acc Id:

NM_001024888 ⟹ NP_001020059

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	178,047,036 - 178,122,643 (+)	NCBI
mRatBN7.2	2	175,749,433 - 175,825,047 (+)	NCBI
Rnor_6.0	2	189,655,702 - 189,732,560 (+)	NCBI
Rnor_5.0	2	209,087,998 - 209,165,690 (+)	NCBI
RGSC_v3.4	2	182,537,125 - 182,615,717 (+)	RGD
Celera	2	169,684,333 - 169,759,364 (+)	RGD

Sequence:

show sequence

CTGGGACACACTGGATTTGTTTGCCAGTTCACTTTTTGAGGGTTGATGGAACTAGAACTTACCC
TTCCCGATCTCATCAGGACTTAAGAGTACTTTTGCCTCTTTGGGCTCAGTTACCTGAAGGAGCT
AGTTACTCCTGTGAATGAAGAGATTTAGGTGTTAATTGCTGTCCCGGAGAATCGTCCCCGCTCT
ATAAAGAATGGATAGAATGACAGAAGATGCTCTTCGTCTGAATCTTTTGAAGAGGAGTTTGGAC
CCGGCAGATGAGCGAGATGATGTCCTGGCAAAACGACTGAAAATGGAGGGGCATGAGGCCATGG
AACGGCTGAAAATGTTGGCACTGCTCAAAAGGAAAGATTTGGCAAATCTTGAGGTACCGCATGA
GTTACCTACCAAACAAGATGGCAGTGGTGTCAAGAGTTATGAAGAGAAACTTAATGGAAATCTC
AGGCCTCATGGAGACAACAGGACTGCTGGAAGGCCAGGCAAAGAAAACATCAATGATGAACCTG
TGGATATGAGTGCTCGACGGAGCGAACCAGACCGAGGAAGGCTAACTCCTTCCCCAGATATAAT
TGTTTTGTCTGATAATGAGGCTTCCAGTCCCCGATCCAGCTCCCGGATGGAAGAGAGACTCAAA
GCAGCCAACCTAGAGATGTTTAAGGGGAAAGGCATTGAGGAACGGCAGCAGCTTATTAAGCAAC
TGAGGGATGAGCTAAGATTGGAAGAAGCTCGTCTGGTGCTGTTAAAGAAACTGAGACAGAGTCA
GCTACAGAAAGAGAATGTGGTCCAAAAGACTCCAGTTGTACAGAATGCAGCATCTATTGTCCAG
CCATCTCCTGCACATGTGGGACAACAAGGCTTATCTAAACTTCCCTCCCGGCCTGGAGCTCAAG
GGATTGAACCTCAAAATCTGAGAACATTACAGGGTCACAGTGTCATCCGTTCAGCAGCCAACAC
CACCCTTCCACACATGTTGATGTCTCAACGTGTTATTGCACCAAATCCAGCCCAACTTCAGGGC
CAGCGGGGGCCACCGAAACCTGGCATTGTACGCACCACAACACCTAACATGAATCCTGCCATCA
GTTACCAACCACAGTCAAGTTCTTCTGTTCCCTGTCAGCGCACAACGTCGTCTGCCATCTATAT
GAACCTCGCCTCCCATATTCAGCCAGGGACTGTGAACAGAGTGTCCTCACCACTTCCTAGCCCC
AGTGCCATGAGCGATGCTGCCAACTCACAGGCTGCAGCCAAATTGGCTCTTCGGAAACAGCTGG
AAAAGACGCTCCTGGAGATACCACCACCAAAACCTCCCGCTCCCTTACTTCACTTCCTGCCTAG
TGCAGCCAATAGCGAGTTTATCTACATGGTAGGCCTGGAAGAAGTCGTACAGAGTGTCATTGAC
AGCCAAGGCAAAAACTGTGCCTCACTTCTGAGGGTCGAACCCTTTGTATGTGCCCAGTGCCGCA
CAGATTTCACCCCTCATTGGAAGCAAGAAAAGAATGGTAAGATCCTCTGTGAGCAGTGTATGAC
TTCCAACCAGAAAAAGGCTCTAAAAGCTGAACACACTAACCGGCTGAAAAACGCTTTCGTTAAA
GCTCTACAGCAGGAACAGGAAATTGAGCAGCGGTTACAGCAGCAGGCAGCACTGTCCCCAACTA
CAGCTCCAGCTGTGTCCAGTGTCAGTAAACAGGAGACCATCATGAGACATCATACACTTCGACA
GGCTCCACAGCCCCAGAGTAGCCTCCAGCGTGGTATACCCACATCTGCCCGCTCCATGCTTTCA
AACTTTGCACAGGCACCCCAGTTGTCTGTGCCAGGTGGCCTCCTTGGCATGCCAGGTGTCAACA
TTGCATACTTGAACACTGGCATCGGAGGACATAAAGCCCCAAGCTTGGCAGACCGGCAGCGTGA
ATACCTTCTAGACATGATCCCTCCCAGGTCTATATCTCAGTCCATCAGTGGGCAGAAATAACGC
CTGTCCCACTCGTGCTGCCCCATCCTTGAACCCTTTCCCCATTTCTCCCACTGCCCCCACTTCC
GTCGCATGCAGTGCCTGTGCTGGTGCCTACCATACACGGAAAGCAAAACCGAAAAAAAAAACAG
AAGACAGAAATAGACATCAACAAGAAAACACATGCCCCGCCCTGCCACCTCCCCTTGATTTCAC
ACTGCTGCGATCTGTTCTCCTGCTGCTCTGTCTTCTCTCTTTGATTTCCTTTAACAGTGAGGTG
GGATCTTTGCCTCTGATAGAGGTCAGAATGAGGTCCTGGGGAGAATTTAAGCCCTTTGATGTGT
GTTTCTAAAGTTTGTTTTATGCTATAATTATTATCATTTTTAATTATAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_008761144 ⟹ XP_008759366

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	178,046,196 - 178,127,633 (+)	NCBI
mRatBN7.2	2	175,748,599 - 175,829,837 (+)	NCBI
Rnor_6.0	2	189,654,871 - 189,735,056 (+)	NCBI

Sequence:

show sequence

GCCCCTCCCCCACCCCCGTCCTGGACCCGCCAGTGGGGTCTGGATCCCACTGTGCCGTCGCCGC
CTCCTTTTCGACGCCTTCACGGCCACCAGAAGAGGCGACCTGGTCGGGAGTTCCGCCGCCGCTG
CCAGAATGGATAGAATGACAGAAGATGCTCTTCGTCTGAATCTTTTGAAGAGGAGTTTGGACCC
GGCAGATGAGCGAGATGATGTCCTGGCAAAACGACTGAAAATGGAGGGGCATGAGGCCATGGAA
CGGCTGAAAATGTTGGCACTGCTCAAAAGGAAAGATTTGGCAAATCTTGAGGTACCGCATGAGT
TACCTACCAAACAAGATGGCAGTGGTGTCAAGAGTTATGAAGAGAAACTTAATGGAAATCTCAG
GCCTCATGGAGACAACAGGACTGCTGGAAGGCCAGGCAAAGAAAACATCAATGATGAACCTGTG
GATATGAGTGCTCGACGGAGCGAACCAGACCGAGGAAGGCTAACTCCTTCCCCAGATATAATTG
TTTTGTCTGATAATGAGGCTTCCAGTCCCCGATCCAGCTCCCGGATGGAAGAGAGACTCAAAGC
AGCCAACCTAGAGATGTTTAAGGGGAAAGGCATTGAGGAACGGCAGCAGCTTATTAAGCAACTG
AGGGATGAGCTAAGATTGGAAGAAGCTCGTCTGGTGCTGTTAAAGAAACTGAGACAGAGTCAGC
TACAGAAAGAGAATGTGGTCCAAAAGACTCCAGTTGTACAGAATGCAGCATCTATTGTCCAGCC
ATCTCCTGCACATGTGGGACAACAAGGCTTATCTAAACTTCCCTCCCGGCCTGGAGCTCAAGGG
ATTGAACCTCAAAATCTGAGAACATTACAGGGTCACAGTGTCATCCGTTCAGCAGCCAACACCA
CCCTTCCACACATGTTGATGTCTCAACGTGTTATTGCACCAAATCCAGCCCAACTTCAGGGCCA
GCGGGGGCCACCGAAACCTGGCATTGTACGCACCACAACACCTAACATGAATCCTGCCATCAGT
TACCAACCACAGTCAAGTTCTTCTGTTCCCTGTCAGCGCACAACGTCGTCTGCCATCTATATGA
ACCTCGCCTCCCATATTCAGCCAGGGACTGTGAACAGAGTGTCCTCACCACTTCCTAGCCCCAG
TGCCATGAGCGATGCTGCCAACTCACAGGCTGCAGCCAAATTGGCTCTTCGGAAACAGCTGGAA
AAGACGCTCCTGGAGATACCACCACCAAAACCTCCCGCTCCCTTACTTCACTTCCTGCCTAGTG
CAGCCAATAGCGAGTTTATCTACATGGTAGGCCTGGAAGAAGTCGTACAGAGTGTCATTGACAG
CCAAGGCAAAAACTGTGCCTCACTTCTGAGGGTCGAACCCTTTGTATGTGCCCAGTGCCGCACA
GATTTCACCCCTCATTGGAAGCAAGAAAAGAATGGTAAGATCCTCTGTGAGCAGTGTATGACTT
CCAACCAGAAAAAGGCTCTAAAAGCTGAACACACTAACCGGCTGAAAAACGCTTTCGTTAAAGC
TCTACAGCAGGAACAGGAAATTGAGCAGCGGTTACAGCAGCAGGCAGCACTGTCCCCAACTACA
GCTCCAGCTGTGTCCAGTGTCAGTAAACAGGAGACCATCATGAGACATCATACACTTCGACAGG
CTCCACAGCCCCAGAGTAGCCTCCAGCGTGGTATACCCACATCTGCCCGCTCCATGCTTTCAAA
CTTTGCACAGGCACCCCAGTTGTCTGTGCCAGGTGGCCTCCTTGGCATGCCAGGTGTCAACATT
GCATACTTGAACACTGGCATCGGAGGACATAAAGCCCCAAGCTTGGCAGACCGGCAGCGTGAAT
ACCTTCTAGACATGATCCCTCCCAGGTCTATATCTCAGTCCATCAGTGGGCAGAAATAACGCCT
GTCCCACTCGTGCTGCCCCATCCTTGAACCCTTTCCCCATTTCTCCCACTGCCCCCACTTCCGT
CGCATGCAGTGCCTGTGCTGGTGCCTACCATACACGGAAAGCAAAACCGAAAAAAAAAACAGAA
GACAGAAATAGACATCAACAAGAAAACACATGCCCCGCCCTGCCACCTCCCCTTGATTTCACAC
TGCTGCGATCTGTTCTCCTGCTGCTCTGTCTTCTCTCTTTGATTTCCTTTAACAGTGAGGTGGG
ATCTTTGCCTCTGATAGAGGTCAGAATGAGGTCCTGGGGAGAATTTAAGCCCTTTGATGTGTGT
TTCTAAAGTTTGTTTTATGCTATAATTATTATCATTTTTAATTATATTGTGTGTTTTCCCTTTG
TTCTGTAGACGGTTAACCCCATCTTCTGTTTTCTTTATGACCCTACCTCCCTCTGCTAACCCTC
CTCCTTTTCTTAAAAAAAAATATATATATATGATATACAATTCAGTGATCACATGCAGATCGCA
GTGGATCCTCAGCTGCCAATAGGAAATAACTGAGAATGTTAGGGACGGAGATGTTGAGTGCACT
TAACCTGAGTTGTGGAGTGGGTGTCATCAAGCAAGTCTGAATAGCGTCCCAGCCATGGCTGGTC
AGGATCTGGAGAGTTCAGGAGGCAGTGTTTTGGTAATGAAGTTGAACTCTGTGACAGTGAGTAA
AAGAGCCTAAAGGGAGAACCTTAAAACAGAAAACTACCTGTAGCTTAACCATGGGATATGGGGG
AAGAGGTGTTACATAAGTTCAGTAGTGTCCCAAAGAGGGCTGCAGCCAGGTCCTGACCTTCTAG
GTGCTTGAAGAGTAAGATGGGTCTCCTGACCCCAGTGAGGACACAGAAGTCTGTTCCAGGCCAA
TCATCTTGAGATTGTTTCTCTTATTTTCTTTGTTAAATTGTCTCTCATCACATCTTCATACCCT
TTAACAAGTGTTCATCTTCCTTCTAACCGGAGTCCCAGAGGAATGGCAGTTTCCAGACTGCAGG
TGGCTGGGTATCCTAGAAGTTGGAATAAGTATACGTGAATCATGTGACAGAAGGGGGAAACTAG
ACATAGAGGAAGAAGAGGTCTCTCTCAGCAGTTGAGAGTCTCAGGTTTCCATCCCTGTCCCCTC
TGAGTGCTGAGAGAGAATGGGTATAGGCCCCCAATCAGGTTGGTATTCCACTCTGACTCTGCTA
CACTGGCTGTAGATCCAATTCCTCAGAGCCAAGCAACTTGTCAAATCAGCTTTGGACCTCAGCT
ATACAAGTATTGTCTTCCCCTAAGCTCCTCTACCCCCAAATTTTTGTTCATTTTGCCCTTTTTT
TTTTTTTTTTTTTTTTTTTTTGGCACTCTTAATGTAAAGAGTAAATTGAATTGTGCAATGTCGC
TGCTCTGAGGTTAGGGAGGTTAGCATTCTTGTGCCCACACTGTGGCAAGGAGGGGGGACCAAGC
TGTTGTTGAGGGAGGTTAGGGAAGCCTGAAGGCGAAGGTTTCCAACTCTCCTCAGAGTGTACAT
GTACAGCCGCTACAGCTCTAGAAGCCGTCAGGGTGGACTCGGGACGCTTTGAGCAAAGATGCAT
GAGGAGTTTATAATACTTTGCCCTTGATAGCCACCTGAGGAAATTCCCTCGTTTTTATTTTTAA
AAACTAAATAATTTTTTTAAAGTAAGAAGGCACTTTTAAAATTGTACACACACACGAATTATAC
ACCTTTCCCATAAAATCTGGGGGTAGGGTGGGAAAAGAAGCTGGATCAAGCTCAATCCCCCACT
CTGGTCTCTTCTTTCCCAGTGCCACTGTGGGTGATTATACTGGCCCTACGGGCCTTCCTGGCTT
TTTCTTCTTCCCTTTCCCTCAGATTCATTGAGCACTTAATAAAGGAGCAGAGATGCAGCCGTGT
CCAGGCTCCCAAGTGGTGAAATGACCTGGAAGCTAGATGCTAGTAACAAGTAGTTTAAGCAGGT
CATTTCAAGTATTTTTCTGGGGAATGTGGTGCCCCTGACTGTAAGTGGTGGGGGAGGGAGGGGG
GGACTAATGGAGCTGGGTTTGGGATTATTTTAAAATTATATATATATATATATAAAAAGATATA
TTCTTACATCTTTTCCTTGCCCTCTGTGCTTTGAAAGCACTGAATAAATTGATTCTGTTTTTCT
CTTCCACAAAATTGGAAGGTTTTTTTCTTCCATTTTTTTTTTTAAATGTTTTTACCAGTCATCT
TGCCTTGTGGCATGTCTGTCTAACTTCTCCCTACCCCATGATGAAGTGCCATTTCTGTTAAGTC
TCCCTGACCCCCAACTCAGAGGTGCTCAGAGGTACACGGTGCCCAAGTTTTTCAGTTGAGATTA
AAAGGAACAGAGAATGTGCAATACCGTCCAGCTGGGGCCTGTCCTTGCCCTGAGCTAGGTCCTC
TCCCTGGGAGCCAGGCCACTCTGACTAGGGTTTGGAAGTAAGCTGTATAGAAATGAAAGGGAGT
GGTGGCAGGAGAAGCCTGTAGTTCAGTGCCTGTTTAGGTGCTGAGGCCATAGGGGAGAGGGTAG
GGTCTTCCCCATTTTTATCCCTTTGGGGTCAATTACATAGAAGCTGCTTGTACTGCTAGTGTAG
CTCTGTGGCCCTTTGCTCAGTCACTGAGATTTGATTTCTCATCCTCTTTTCCCATCATCATCCT
CTTCCCAGGAATTAACGAGAGGGATGAAATCTTTCTTAATCATGGTGAAGTATTAGCTTCCATC
TCCTCCCTTAGGTCCCGCCCTGTCCGTTCCCCTTTCTTCAAGCCTCTACATTTTACATCACCTA
TTGCCTTGTGTCCTTCCAGGCCTTTTTTTTTTTTTTTTTTTTTTTT

hide sequence

RefSeq Acc Id:

XM_039102301 ⟹ XP_038958229

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	178,046,192 - 178,127,633 (+)	NCBI
mRatBN7.2	2	175,748,594 - 175,829,837 (+)	NCBI

RefSeq Acc Id:

XM_039102302 ⟹ XP_038958230

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	178,046,192 - 178,127,633 (+)	NCBI
mRatBN7.2	2	175,748,594 - 175,829,837 (+)	NCBI

RefSeq Acc Id:

XM_063281823 ⟹ XP_063137893

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	178,092,455 - 178,127,633 (+)	NCBI

RefSeq Acc Id:

XM_063281824 ⟹ XP_063137894

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	178,046,196 - 178,127,633 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001020059	(Get FASTA)	NCBI Sequence Viewer
	XP_008759366	(Get FASTA)	NCBI Sequence Viewer
	XP_038958229	(Get FASTA)	NCBI Sequence Viewer
	XP_038958230	(Get FASTA)	NCBI Sequence Viewer
	XP_063137893	(Get FASTA)	NCBI Sequence Viewer
	XP_063137894	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH97428	(Get FASTA)	NCBI Sequence Viewer
	EDM00572	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000021502.3
	ENSRNOP00000071152
	ENSRNOP00000071152.2
	ENSRNOP00000091300
	ENSRNOP00000091300.1

RefSeq Acc Id:

NP_001020059 ⟸ NM_001024888

- UniProtKB:

Q4V8E1 (UniProtKB/TrEMBL), A6J6L7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MDRMTEDALRLNLLKRSLDPADERDDVLAKRLKMEGHEAMERLKMLALLKRKDLANLEVPHELP
TKQDGSGVKSYEEKLNGNLRPHGDNRTAGRPGKENINDEPVDMSARRSEPDRGRLTPSPDIIVL
SDNEASSPRSSSRMEERLKAANLEMFKGKGIEERQQLIKQLRDELRLEEARLVLLKKLRQSQLQ
KENVVQKTPVVQNAASIVQPSPAHVGQQGLSKLPSRPGAQGIEPQNLRTLQGHSVIRSAANTTL
PHMLMSQRVIAPNPAQLQGQRGPPKPGIVRTTTPNMNPAISYQPQSSSSVPCQRTTSSAIYMNL
ASHIQPGTVNRVSSPLPSPSAMSDAANSQAAAKLALRKQLEKTLLEIPPPKPPAPLLHFLPSAA
NSEFIYMVGLEEVVQSVIDSQGKNCASLLRVEPFVCAQCRTDFTPHWKQEKNGKILCEQCMTSN
QKKALKAEHTNRLKNAFVKALQQEQEIEQRLQQQAALSPTTAPAVSSVSKQETIMRHHTLRQAP
QPQSSLQRGIPTSARSMLSNFAQAPQLSVPGGLLGMPGVNIAYLNTGIGGHKAPSLADRQREYL
LDMIPPRSISQSISGQK

hide sequence

RefSeq Acc Id:	XP_008759366 ⟸ XM_008761144
- Peptide Label:	isoform X3
- UniProtKB:	Q4V8E1 (UniProtKB/TrEMBL), A6J6L7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDRMTEDALRLNLLKRSLDPADERDDVLAKRLKMEGHEAMERLKMLALLKRKDLANLEVPHELP TKQDGSGVKSYEEKLNGNLRPHGDNRTAGRPGKENINDEPVDMSARRSEPDRGRLTPSPDIIVL SDNEASSPRSSSRMEERLKAANLEMFKGKGIEERQQLIKQLRDELRLEEARLVLLKKLRQSQLQ KENVVQKTPVVQNAASIVQPSPAHVGQQGLSKLPSRPGAQGIEPQNLRTLQGHSVIRSAANTTL PHMLMSQRVIAPNPAQLQGQRGPPKPGIVRTTTPNMNPAISYQPQSSSSVPCQRTTSSAIYMNL ASHIQPGTVNRVSSPLPSPSAMSDAANSQAAAKLALRKQLEKTLLEIPPPKPPAPLLHFLPSAA NSEFIYMVGLEEVVQSVIDSQGKNCASLLRVEPFVCAQCRTDFTPHWKQEKNGKILCEQCMTSN QKKALKAEHTNRLKNAFVKALQQEQEIEQRLQQQAALSPTTAPAVSSVSKQETIMRHHTLRQAP QPQSSLQRGIPTSARSMLSNFAQAPQLSVPGGLLGMPGVNIAYLNTGIGGHKAPSLADRQREYL LDMIPPRSISQSISGQK hide sequence

Ensembl Acc Id:

ENSRNOP00000021502 ⟸ ENSRNOT00000021502

Ensembl Acc Id:

ENSRNOP00000071152 ⟸ ENSRNOT00000086285

RefSeq Acc Id:	XP_038958229 ⟸ XM_039102301
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6AFB3 (UniProtKB/TrEMBL), A6J6L7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038958230 ⟸ XM_039102302
- Peptide Label:	isoform X2
- UniProtKB:	A6J6L7 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000091300 ⟸ ENSRNOT00000117370

RefSeq Acc Id:	XP_063137894 ⟸ XM_063281824
- Peptide Label:	isoform X4
- UniProtKB:	A6J6L7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063137893 ⟸ XM_063281823
- Peptide Label:	isoform X3
- UniProtKB:	Q4V8E1 (UniProtKB/TrEMBL), A6J6L7 (UniProtKB/TrEMBL)

Protein Domains

GATA-type

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q4V8E1-F1-model_v2	AlphaFold	Q4V8E1	1-593	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1308533	AgrOrtholog
BioCyc Gene	G2FUF-52352	BioCyc
Ensembl Genes	ENSRNOG00000015553	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000021502.7	UniProtKB/TrEMBL
	ENSRNOT00000086285	ENTREZGENE
	ENSRNOT00000086285.2	UniProtKB/TrEMBL
	ENSRNOT00000117370	ENTREZGENE
	ENSRNOT00000117370.1	UniProtKB/TrEMBL
Gene3D-CATH	3.30.50.10	UniProtKB/TrEMBL
	6.10.250.1650	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7455294	IMAGE-MGC_LOAD
InterPro	P66	UniProtKB/TrEMBL
	P66_CC	UniProtKB/TrEMBL
	Znf_GATA	UniProtKB/TrEMBL
	Znf_NHR/GATA	UniProtKB/TrEMBL
KEGG Report	rno:310614	UniProtKB/TrEMBL
MGC_CLONE	MGC:114476	IMAGE-MGC_LOAD
NCBI Gene	310614	ENTREZGENE
PANTHER	PTHR13455	UniProtKB/TrEMBL
	TRANSCRIPTIONAL REPRESSOR P66-BETA	UniProtKB/TrEMBL
Pfam	GATA	UniProtKB/TrEMBL
	P66_CC	UniProtKB/TrEMBL
PhenoGen	Gatad2b	PhenoGen
PROSITE	GATA_ZN_FINGER_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000015553	RatGTEx
Superfamily-SCOP	Glucocorticoid receptor-like (DNA-binding domain)	UniProtKB/TrEMBL
UniProt	A0A0G2JZR6_RAT	UniProtKB/TrEMBL
	A0A8I6AFB3	ENTREZGENE, UniProtKB/TrEMBL
	A6J6L7	ENTREZGENE, UniProtKB/TrEMBL
	Q4V8E1	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2006-03-30	Gatad2b	GATA zinc finger domain containing 2B	RGD1308533	similar to transcription repressor p66	Symbol and Name updated	1299863	APPROVED
2005-12-06	RGD1308533	similar to transcription repressor p66	RGD1308533_predicted	similar to transcription repressor p66 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-20	RGD1308533_predicted	similar to transcription repressor p66 (predicted)	LOC310614_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC310614_predicted	similar to transcription repressor p66 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - OMIM

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