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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628841
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Trpv1
Name: transient receptor potential cation channel, subfamily V, member 1
Acc ID: CHEBI:67081
Term: cannabigerolic acid
Definition: A dihydroxybenzoic acid that is olivetolic acid in which the hydrogen at position 3 is substituted by a geranyl group. A biosynthetic precursor to Delta(9)-tetrahydrocannabinol, the principal psychoactive constituent of the cannabis plant.
Chemical ID: MESH:C100679
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Trpv1increases activityISORGD:7331976480464CTDcannabigerolic acid results in increased activity of TRPV1 proteinPMID:31096838
Trpv1multiple interactionsISORGD:7331976480464CTD[cannabigerolic acid results in increased activity of TRPV1 protein] which results in increased uptake of CalciumPMID:31096838
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