Gadd45g (growth arrest and DNA-damage-inducible, gamma) - Rat Genome Database

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Gene: Gadd45g (growth arrest and DNA-damage-inducible, gamma) Rattus norvegicus
Analyze
Symbol: Gadd45g
Name: growth arrest and DNA-damage-inducible, gamma
RGD ID: 1311796
Description: Predicted to enable identical protein binding activity. Predicted to be involved in several processes, including positive regulation of MAPK cascade; positive regulation of apoptotic process; and positive regulation of cold-induced thermogenesis. Predicted to act upstream of or within negative regulation of protein kinase activity and positive regulation of MAPK cascade. Predicted to be active in cytoplasm and nucleus. Biomarker of mesangial proliferative glomerulonephritis. Orthologous to human GADD45G (growth arrest and DNA damage inducible gamma); PARTICIPATES IN interleukin-12 signaling pathway; p38 MAPK signaling pathway; cell cycle pathway, mitotic; INTERACTS WITH (S)-colchicine; 1,3-dinitrobenzene; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: GADD45gamma; growth arrest and DNA damage inducible; growth arrest and DNA damage-inducible protein GADD45 gamma; growth arrest and DNA-damage-inducible 45 gamma; growth arrest and DNA-damage-inducible protein GADD45 gamma; LOC291005
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81713,528,606 - 13,530,351 (-)NCBIGRCr8
mRatBN7.21713,376,842 - 13,378,587 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1713,376,839 - 13,378,610 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1713,306,579 - 13,308,325 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01714,916,605 - 14,918,351 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01713,233,590 - 13,235,336 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01713,391,474 - 13,393,219 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1713,391,467 - 13,393,243 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01715,469,297 - 15,471,042 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41719,230,896 - 19,232,641 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11719,230,892 - 19,312,040 (-)NCBI
Celera1713,134,806 - 13,136,551 (-)NCBICelera
Cytogenetic Map17p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
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Reference
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Source
Original Reference(s)
Gadd45gRatmesangial proliferative glomerulonephritis  IEP 14700866mRNA,protein:increased expression:kidneyRGD 

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Object Symbol
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Original Reference(s)
Gadd45gRat(+)-dexrazoxane multiple interactionsISORGD:13234376480464Dexrazoxane inhibits the reaction [Idarubicin results in increased expression of GADD45G mRNA]CTDPMID:28973540
Gadd45gRat(1->4)-beta-D-glucan multiple interactionsISORGD:13234376480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of GADD45G mRNACTDPMID:36331819
Gadd45gRat(S)-colchicine increases expressionEXP 6480464Colchicine results in increased expression of GADD45G mRNACTDPMID:20624997
Gadd45gRat1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane increases expressionISORGD:132343764804642,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane results in increased expression of GADD45G mRNACTDPMID:20826375
Gadd45gRat1,1-dichloroethene decreases expressionISORGD:13234376480464vinylidene chloride results in decreased expression of GADD45G mRNACTDPMID:26682919
Gadd45gRat1,3-dinitrobenzene increases expressionEXP 64804643-dinitrobenzene results in increased expression of GADD45G mRNACTDPMID:21983209
Gadd45gRat17alpha-ethynylestradiol multiple interactionsISORGD:13234376480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of GADD45G mRNACTDPMID:17942748
Gadd45gRat17alpha-ethynylestradiol increases expressionEXP 6480464Ethinyl Estradiol results in increased expression of GADD45G mRNACTDPMID:16174780|PMID:17351261
Gadd45gRat17alpha-ethynylestradiol increases expressionISORGD:13234376480464Ethinyl Estradiol results in increased expression of GADD45G mRNACTDPMID:17942748
Gadd45gRat17alpha-ethynylestradiol affects expressionISORGD:13234376480464Ethinyl Estradiol affects the expression of GADD45G mRNACTDPMID:17555576
Gadd45gRat17beta-estradiol increases expressionISORGD:13234376480464Estradiol results in increased expression of GADD45G mRNACTDPMID:19484750|PMID:20826375|PMID:25210133|PMID:39298647
Gadd45gRat17beta-estradiol affects expressionEXP 6480464Estradiol affects the expression of GADD45G mRNACTDPMID:32145629
Gadd45gRat17beta-estradiol increases expressionISORGD:13234366480464Estradiol results in increased expression of GADD45G mRNACTDPMID:19484750
Gadd45gRat17beta-estradiol affects expressionISORGD:13234366480464Estradiol affects the expression of GADD45G mRNACTDPMID:22574217
Gadd45gRat17beta-estradiol affects expressionISORGD:13234376480464Estradiol affects the expression of GADD45G mRNACTDPMID:15598610
Gadd45gRat17beta-hydroxy-5alpha-androstan-3-one increases expressionISORGD:13234366480464Dihydrotestosterone results in increased expression of GADD45G mRNACTDPMID:29581250
Gadd45gRat2,2',4,4'-Tetrabromodiphenyl ether affects expressionISORGD:132343764804642,2',4,4'-tetrabromodiphenyl ether affects the expression of GADD45G mRNACTDPMID:30294300
Gadd45gRat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISORGD:13234376480464[Tetrachlorodibenzodioxin co-treated with EGF protein] inhibits the reaction [[Dexamethasone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine more ...CTDPMID:16054899|PMID:17942748|PMID:21889950|PMID:25975270
Gadd45gRat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of GADD45G mRNACTDPMID:33387578
Gadd45gRat2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of GADD45G mRNACTDPMID:34747641

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Biological Process
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Original Reference(s)
Gadd45gRatapoptotic process involved_inIEAUniProtKB-KW:KW-00531600115GO_REF:0000043UniProtGO_REF:0000043
Gadd45gRatcell differentiation involved_inIEAUniProtKB-KW:KW-02211600115GO_REF:0000043UniProtGO_REF:0000043
Gadd45gRatnegative regulation of protein kinase activity acts_upstream_of_or_withinISORGD:13234371624291 PMID:12124778RGDPMID:12124778
Gadd45gRatpositive regulation of apoptotic process involved_inISORGD:13234361624291 PMID:9827804RGDPMID:9827804
Gadd45gRatpositive regulation of apoptotic process involved_inIEAUniProtKB:O95257|ensembl:ENSP000002525061600115GO_REF:0000107EnsemblGO_REF:0000107
Gadd45gRatpositive regulation of cold-induced thermogenesis involved_inISSUniProtKB:Q9Z11113673821PMID:25071184YuBioLab 
Gadd45gRatpositive regulation of cold-induced thermogenesis involved_inISORGD:13234371624291 PMID:25071184RGDPMID:25071184
Gadd45gRatpositive regulation of JNK cascade involved_inISORGD:13234361624291 PMID:9827804RGDPMID:9827804
Gadd45gRatpositive regulation of JNK cascade involved_inIEAUniProtKB:O95257|ensembl:ENSP000002525061600115GO_REF:0000107EnsemblGO_REF:0000107
Gadd45gRatpositive regulation of MAPK cascade acts_upstream_of_or_withinISORGD:13234371624291 PMID:12213961RGDPMID:12213961
Gadd45gRatpositive regulation of p38MAPK cascade involved_inISORGD:13234361624291 PMID:9827804RGDPMID:9827804
Gadd45gRatpositive regulation of p38MAPK cascade involved_inIEAUniProtKB:O95257|ensembl:ENSP000002525061600115GO_REF:0000107EnsemblGO_REF:0000107
Gadd45gRatregulation of cell cycle involved_inIEAInterPro:IPR0248241600115GO_REF:0000002InterProGO_REF:0000002
Gadd45gRatregulation of cell cycle acts_upstream_of_or_withinISORGD:13234371624291 PMID:12124778RGDPMID:12124778
Gadd45gRatregulation of cell cycle involved_inIBAMGI:107776|MGI:107799|MGI:1346325|PANTHER:PTN0008236591600115GO_REF:0000033GO_CentralGO_REF:0000033
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Cellular Component

  
Object Symbol
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Original Reference(s)
Gadd45gRatcytoplasm located_inISORGD:13234361624291 PMID:9827804RGDPMID:9827804
Gadd45gRatcytoplasm is_active_inIBAPANTHER:PTN000823659|UniProtKB:O75293|UniProtKB:O95257|UniProtKB:P245221600115GO_REF:0000033GO_CentralGO_REF:0000033
Gadd45gRatcytoplasm located_inIEAUniProtKB:O95257|ensembl:ENSP000002525061600115GO_REF:0000107EnsemblGO_REF:0000107
Gadd45gRatnucleus located_inIEAInterPro:IPR0248241600115GO_REF:0000002InterProGO_REF:0000002
Gadd45gRatnucleus is_active_inIBAFB:FBgn0033153|MGI:107799|PANTHER:PTN000823659|UniProtKB:O75293|UniProtKB:O95257|UniProtKB:P245221600115GO_REF:0000033GO_CentralGO_REF:0000033
Gadd45gRatnucleus located_inIEAUniProtKB:O95257|ensembl:ENSP000002525061600115GO_REF:0000107EnsemblGO_REF:0000107
Gadd45gRatnucleus located_inISORGD:13234361624291 PMID:9827804RGDPMID:9827804

Molecular Function

  
Object Symbol
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Reference
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Source
Original Reference(s)
Gadd45gRatidentical protein binding enablesISORGD:13234371624291UniProtKB:Q9Z111 PMID:18445651RGDPMID:18445651
Gadd45gRatprotein binding enablesISORGD:13234361624291UniProtKB:A6NK89|UniProtKB:P08949-2|UniProtKB:P12814|UniProtKB:P57060|UniProtKB:Q04864|UniProtKB:Q0D2J5|UniProtKB:Q13561|UniProtKB:Q15293|UniProtKB:Q5T3J3|UniProtKB:Q6IC98|UniProtKB:Q6QNY1|UniProtKB:Q8IYX8-2|UniProtKB:Q8N3J9|UniProtKB:Q8N7W2-2|UniProtKB:Q8NDB6|UniProtKB:Q8TAE8|UniProtKB:Q8TED9|UniProtKB:Q92600-3|UniProtKB:Q92993|UniProtKB:Q96D03|UniProtKB:Q96MT7|UniProtKB:Q99598|UniProtKB:Q9BPX5|UniProtKB:Q9BVJ6|UniProtKB:Q9H0I2|UniProtKB:Q9P2H0|UniProtKB:Q9Y3A4|UniProtKB:Q9Y3C7|UniProtKB:Q9Y6R4 PMID:12052864, PMID:12716909, PMID:15383276, PMID:16189514, PMID:21900206, PMID:21988832, PMID:25416956, PMID:31515488, PMID:32296183, PMID:33961781RGDPMID:12052864|PMID:12716909|PMID:15383276|PMID:16189514|PMID:21900206|PMID:21988832|PMID:25416956|PMID:31515488|PMID:32296183|PMID:33961781
Gadd45gRatprotein binding enablesISORGD:13234371624291PR:P24860|UniProtKB:P12004|UniProtKB:P17918|UniProtKB:P39689 PMID:11022036, PMID:12124778RGDPMID:11022036|PMID:12124778

Imported Annotations - KEGG (archival)

Object Symbol
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Term
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Original Reference(s)
Gadd45gRatcell cycle pathway, mitotic  IEA 6907045 KEGGrno:04110
Gadd45gRatmitogen activated protein kinase signaling pathway   IEA 6907045 KEGGrno:04010
Gadd45gRatp53 signaling pathway   IEA 6907045 KEGGrno:04115

Imported Annotations - PID (archival)

Object Symbol
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Term
Qualifier
Evidence
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Reference
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Source
Original Reference(s)
Gadd45gRatinterleukin-12 signaling pathway  ISORGD:13234366484113 PIDPID:200045
Gadd45gRatp38 MAPK signaling pathway   ISORGD:13234366484113 PIDPID:200018

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#
Reference Title
Reference Citation
1. GADD45¿ regulates the thermogenic capacity of brown adipose tissue. Gantner ML, etal., Proc Natl Acad Sci U S A. 2014 Aug 12;111(32):11870-5. doi: 10.1073/pnas.1406638111. Epub 2014 Jul 28.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
7. GOA pipeline RGD automated data pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Gene expression profile and overexpression of apoptosis-related genes (NGFI-B and Gadd 45 gamma) in early phase of Thy-1 nephritis model. Xu JH, etal., Cell Tissue Res. 2006 Oct;326(1):159-68. doi: 10.1007/s00441-006-0214-4. Epub 2006 May 31.
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PMID:9827804   PMID:10100865   PMID:12124778   PMID:12213961   PMID:12477932   PMID:18445651   PMID:19882653   PMID:27086974   PMID:32828305  



Gadd45g
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81713,528,606 - 13,530,351 (-)NCBIGRCr8
mRatBN7.21713,376,842 - 13,378,587 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1713,376,839 - 13,378,610 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1713,306,579 - 13,308,325 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01714,916,605 - 14,918,351 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01713,233,590 - 13,235,336 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01713,391,474 - 13,393,219 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1713,391,467 - 13,393,243 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01715,469,297 - 15,471,042 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41719,230,896 - 19,232,641 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11719,230,892 - 19,312,040 (-)NCBI
Celera1713,134,806 - 13,136,551 (-)NCBICelera
Cytogenetic Map17p14NCBI
GADD45G
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38989,605,012 - 89,606,555 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl989,605,012 - 89,606,555 (+)EnsemblGRCh38hg38GRCh38
GRCh37992,219,927 - 92,221,470 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36991,409,748 - 91,411,290 (+)NCBINCBI36Build 36hg18NCBI36
Build 34989,449,481 - 89,451,021NCBI
Celera962,803,226 - 62,804,769 (+)NCBICelera
Cytogenetic Map9q22.2NCBI
HuRef962,051,611 - 62,053,154 (+)NCBIHuRef
CHM1_1992,368,717 - 92,370,261 (+)NCBICHM1_1
T2T-CHM13v2.09101,768,936 - 101,770,479 (+)NCBIT2T-CHM13v2.0
Gadd45g
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391352,000,711 - 52,002,511 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1352,000,714 - 52,002,504 (+)EnsemblGRCm39 Ensembl
GRCm381351,846,675 - 51,848,475 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1351,846,678 - 51,848,468 (+)EnsemblGRCm38mm10GRCm38
MGSCv371351,942,044 - 51,943,844 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361351,859,189 - 51,860,971 (+)NCBIMGSCv36mm8
Celera1352,922,160 - 52,923,960 (+)NCBICelera
Cytogenetic Map13A5NCBI
cM Map1326.36NCBI
Gadd45g
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555152,422,998 - 2,424,851 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555152,423,137 - 2,424,851 (-)NCBIChiLan1.0ChiLan1.0
GADD45G
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21149,854,190 - 49,855,744 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1949,856,577 - 49,858,126 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0960,695,307 - 60,696,860 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1988,740,411 - 88,741,965 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl988,740,411 - 88,741,958 (+)Ensemblpanpan1.1panPan2
GADD45G
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1196,745,001 - 96,746,535 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl196,744,985 - 96,746,520 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha197,197,788 - 97,199,313 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0197,346,707 - 97,348,232 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl197,346,691 - 97,348,226 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1196,974,994 - 96,976,519 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0196,693,996 - 96,695,522 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0197,452,325 - 97,453,850 (-)NCBIUU_Cfam_GSD_1.0
Gadd45g
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494411,357,046 - 11,358,722 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936780501,681 - 503,305 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936780501,452 - 503,272 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GADD45G
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl141,165,982 - 1,167,529 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1141,166,000 - 1,167,538 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2141,421,152 - 1,422,690 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GADD45G
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.112100,097,990 - 100,099,541 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl12100,097,967 - 100,099,697 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603888,422,292 - 88,423,839 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gadd45g
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476522,959,373 - 22,961,491 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476522,959,751 - 22,961,371 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Gadd45g
5 total Variants

Predicted Target Of
Summary Value
Count of predictions:303
Count of miRNA genes:175
Interacting mature miRNAs:203
Transcripts:ENSRNOT00000018252
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


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The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17169599340Rat
2300002Iddm36Insulin dependent diabetes mellitus QTL 361.98blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)17999128640540197Rat
631499Stl1Serum triglyceride level QTL 13.6blood triglyceride amount (VT:0002644)blood triglyceride level (CMO:0000118)17327139827389946Rat
2293664Bmd28Bone mineral density QTL 285.10.0001femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)17435448727028127Rat
1300123Bp194Blood pressure QTL 1942.82arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)17211514934551001Rat
1582224Epfw4Epididymal fat weight QTL 43.50.0058epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)17920136523653323Rat
1582225Bw67Body weight QTL 676.20.0001body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
1582226Bw64Body weight QTL 644.20.0017body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
1354651Lmblg2Limb length QTL 26tibia length (VT:0004357)tibia length (CMO:0000450)17429913069599340Rat
10401807Kidm52Kidney mass QTL 52kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)17131701463Rat

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C86281  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21713,376,871 - 13,377,056 (+)MAPPERmRatBN7.2
Rnor_6.01713,391,504 - 13,391,688NCBIRnor6.0
Rnor_5.01715,469,327 - 15,469,511UniSTSRnor5.0
RGSC_v3.41719,230,926 - 19,231,110UniSTSRGSC3.4
Celera1713,134,836 - 13,135,020UniSTS
Cytogenetic Map17p14UniSTS
PMC86941P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21713,377,064 - 13,377,420 (+)MAPPERmRatBN7.2
Rnor_6.01713,391,697 - 13,392,052NCBIRnor6.0
Rnor_5.01715,469,520 - 15,469,875UniSTSRnor5.0
RGSC_v3.41719,231,119 - 19,231,474UniSTSRGSC3.4
Celera1713,135,029 - 13,135,384UniSTS
Cytogenetic Map17p14UniSTS
UniSTS:237015  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81713,528,693 - 13,528,892 (+)Marker Load Pipeline
mRatBN7.21713,376,929 - 13,377,128 (+)MAPPERmRatBN7.2
Rnor_6.01713,391,562 - 13,391,760NCBIRnor6.0
Rnor_5.01715,469,385 - 15,469,583UniSTSRnor5.0
RGSC_v3.41719,230,984 - 19,231,182UniSTSRGSC3.4
Celera1713,134,894 - 13,135,092UniSTS
Cytogenetic Map17p14UniSTS
UniSTS:546781  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81713,529,695 - 13,530,291 (+)Marker Load Pipeline
mRatBN7.21713,377,931 - 13,378,527 (+)MAPPERmRatBN7.2
Rnor_6.01713,392,564 - 13,393,159NCBIRnor6.0
Rnor_5.01715,470,387 - 15,470,982UniSTSRnor5.0
Celera1713,135,896 - 13,136,491UniSTS
Cytogenetic Map17p14UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000018252   ⟹   ENSRNOP00000018251
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1713,376,839 - 13,378,610 (-)Ensembl
Rnor_6.0 Ensembl1713,391,467 - 13,393,243 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000106900   ⟹   ENSRNOP00000086432
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1713,376,839 - 13,378,610 (-)Ensembl
RefSeq Acc Id: NM_001077640   ⟹   NP_001071108
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81713,528,606 - 13,530,351 (-)NCBI
mRatBN7.21713,376,842 - 13,378,587 (-)NCBI
Rnor_6.01713,391,474 - 13,393,219 (-)NCBI
Rnor_5.01715,469,297 - 15,471,042 (-)NCBI
RGSC_v3.41719,230,896 - 19,232,641 (-)RGD
Celera1713,134,806 - 13,136,551 (-)RGD
Sequence:
Protein RefSeqs NP_001071108 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI68643 (Get FASTA)   NCBI Sequence Viewer  
  BAA78094 (Get FASTA)   NCBI Sequence Viewer  
  EDL98082 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000018251
  ENSRNOP00000018251.4
GenBank Protein Q9WTQ7 (Get FASTA)   NCBI Sequence Viewer  
  QST78375 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001071108   ⟸   NM_001077640
- UniProtKB: Q9WTQ7 (UniProtKB/Swiss-Prot),   B5DEF0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000018251   ⟸   ENSRNOT00000018252
Ensembl Acc Id: ENSRNOP00000086432   ⟸   ENSRNOT00000106900
Name Modeler Protein Id AA Range Protein Structure
AF-Q9WTQ7-F1-model_v2 AlphaFold Q9WTQ7 1-159 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13700337
Promoter ID:EPDNEW_R10860
Type:single initiation site
Name:Gadd45g_1
Description:growth arrest and DNA-damage-inducible, gamma
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01713,393,237 - 13,393,297EPDNEW


1 to 19 of 19 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-10076 BioCyc
Ensembl Genes ENSRNOG00000013090 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000018252 ENTREZGENE
  ENSRNOT00000018252.8 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.1330.30 UniProtKB/Swiss-Prot
InterPro GADD45 UniProtKB/Swiss-Prot
  L30e-like UniProtKB/Swiss-Prot
  Ribosomal_L7Ae/L30e/S12e/Gad45 UniProtKB/Swiss-Prot
KEGG Report rno:291005 UniProtKB/Swiss-Prot
NCBI Gene 291005 ENTREZGENE
PANTHER GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEIN GADD45 GAMMA UniProtKB/Swiss-Prot
  PTHR10411 UniProtKB/Swiss-Prot
Pfam Ribosomal_L7Ae UniProtKB/Swiss-Prot
PhenoGen Gadd45g PhenoGen
RatGTEx ENSRNOG00000013090 RatGTEx
Superfamily-SCOP SSF55315 UniProtKB/Swiss-Prot
UniProt A0A8I6A8S9_RAT UniProtKB/TrEMBL
  B5DEF0 ENTREZGENE, UniProtKB/TrEMBL
  GA45G_RAT UniProtKB/Swiss-Prot, ENTREZGENE
1 to 19 of 19 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-11-14 Gadd45g  growth arrest and DNA-damage-inducible, gamma  Gadd45g  growth arrest and DNA-damage-inducible 45 gamma  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Gadd45g  growth arrest and DNA-damage-inducible 45 gamma  Gadd45g_predicted  growth arrest and DNA-damage-inducible 45 gamma (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Gadd45g_predicted  growth arrest and DNA-damage-inducible 45 gamma (predicted)      Symbol and Name status set to approved 70820 APPROVED