Itgb1 (integrin subunit beta 1) - Rat Genome Database

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Gene: Itgb1 (integrin subunit beta 1) Rattus norvegicus
Analyze
Symbol: Itgb1
Name: integrin subunit beta 1
RGD ID: 2927
Description: Exhibits several functions, including cytoskeletal protein binding activity; enzyme binding activity; and fibronectin binding activity. Is predicted to contribute to C-X3-C chemokine binding activity. Involved in several processes, including bicellular tight junction assembly; regulation of cell projection organization; and regulation of neuron differentiation. Localizes to several cellular components, including focal adhesion; hemidesmosome; and integral component of plasma membrane. Predicted to colocalize with cytoplasmic vesicle; perinuclear region of cytoplasm; and ruffle membrane. Used to study hydrocephalus and myocardial infarction. Biomarker of glomerulonephritis. Orthologous to human ITGB1 (integrin subunit beta 1); PARTICIPATES IN integrin mediated signaling pathway; altered integrin mediated signaling pathway; altered Reelin signaling pathway; INTERACTS WITH (+)-pilocarpine; (R)-adrenaline; (R)-mevalonic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: beta OL; beta oligodendroglia; collagen alpha-1(I) chain-like; fibronectin receptor subunit beta; Integrin beta 1; integrin beta 1 (fibronectin receptor beta); integrin beta-1; integrin VLA-4 subunit beta; integrin, beta 1; LOC102556297; VLA-4 subunit beta
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21956,705,123 - 56,753,199 (+)NCBI
Rnor_6.0 Ensembl1961,677,542 - 61,725,535 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01961,677,512 - 61,725,537 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01972,324,582 - 72,372,325 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41958,600,095 - 58,647,531 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11958,605,791 - 58,652,463 (-)NCBI
Celera1956,037,604 - 56,085,651 (+)NCBICelera
Cytogenetic Map19q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-pilocarpine  (EXP,ISO)
(20S)-ginsenoside Rh1  (ISO)
(24S)-24-hydroxycholesterol  (ISO)
(25R)-cholest-5-ene-3beta,26-diol  (ISO)
(R)-adrenaline  (EXP)
(R)-mevalonic acid  (EXP,ISO)
(S)-nicotine  (ISO)
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane  (EXP)
1,2-dimethylhydrazine  (ISO)
1,3-dinitrobenzene  (EXP)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dinitrotoluene  (EXP)
2,5-hexanedione  (EXP)
2,6-dinitrotoluene  (EXP)
2-deoxy-D-glucose  (ISO)
2-methoxyethanol  (EXP)
2-nitrotoluene  (EXP)
26-hydroxycholesterol  (ISO)
3',5'-cyclic AMP  (EXP)
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (EXP,ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-diaminodiphenylmethane  (EXP)
5-azacytidine  (ISO)
7alpha-hydroxycholesterol  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (EXP,ISO)
all-trans-retinoic acid  (ISO)
all-trans-retinol  (ISO)
aluminium oxide  (ISO)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
artesunate  (ISO)
atorvastatin calcium  (EXP,ISO)
atrazine  (ISO)
aucubin  (ISO)
beauvericin  (ISO)
benomyl  (ISO)
benzo[a]pyrene  (ISO)
beta-carotene  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
blebbistatin  (ISO)
bromochloroacetic acid  (EXP)
bucladesine  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calciol  (ISO)
carbamazepine  (ISO)
carbendazim  (ISO)
carbon nanotube  (ISO)
carmustine  (ISO)
chloroacetaldehyde  (ISO)
chloropicrin  (ISO)
chrysene  (ISO)
cidofovir anhydrous  (ISO)
cisplatin  (ISO)
cocaine  (ISO)
colforsin daropate hydrochloride  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (EXP,ISO)
curcumin  (ISO)
cyclosporin A  (ISO)
D-glucose  (EXP,ISO)
DDT  (ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
diallyl trisulfide  (ISO)
diarsenic trioxide  (ISO)
dibenzo[a,l]pyrene  (ISO)
dibutyl phthalate  (EXP,ISO)
dichlorine  (EXP)
diclofenac  (ISO)
dicrotophos  (ISO)
dimethylarsinic acid  (EXP)
dioxygen  (EXP,ISO)
disulfiram  (ISO)
diuron  (EXP)
dobutamine  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
enniatin  (ISO)
erlotinib hydrochloride  (EXP)
ethanol  (ISO)
ethyl trans-caffeate  (ISO)
etodolac  (ISO)
eugenol  (ISO)
fenamidone  (ISO)
fenhexamid  (ISO)
fenofibrate  (EXP)
folic acid  (ISO)
fructose  (ISO)
fulvestrant  (ISO)
furan  (EXP)
gefitinib  (ISO)
genistein  (ISO)
geranylgeraniol  (EXP,ISO)
ginsenoside C-K  (ISO)
glucose  (EXP,ISO)
glyphosate  (ISO)
hydrogen peroxide  (ISO)
hydroquinone  (ISO)
ifosfamide  (ISO)
isoprenaline  (EXP,ISO)
latrunculin A  (ISO)
lead diacetate  (ISO)
lithocholic acid  (ISO)
lovastatin  (ISO)
magnesium atom  (ISO)
manganese atom  (EXP)
manganese(0)  (EXP)
medroxyprogesterone acetate  (ISO)
mercury atom  (EXP)
mercury(0)  (EXP)
metformin  (EXP)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
methylseleninic acid  (ISO)
ML-7  (ISO)
monocrotaline  (ISO)
morusin  (ISO)
N-acetyl-L-cysteine  (ISO)
N-nitrosodiethylamine  (EXP)
N-nitrosodimethylamine  (EXP)
nicotine  (ISO)
notoginsenoside R1  (ISO)
ozone  (EXP)
paclitaxel  (EXP)
paracetamol  (EXP,ISO)
pentane-2,3-dione  (EXP)
phenobarbital  (EXP)
phenytoin  (ISO)
pirinixic acid  (ISO)
potassium iodide  (EXP)
pravastatin  (EXP,ISO)
progesterone  (EXP)
prostaglandin E2  (EXP)
quercetin  (EXP,ISO)
quercitrin  (ISO)
raloxifene  (ISO)
resveratrol  (ISO)
rimonabant  (ISO)
SB 431542  (ISO)
Shikonin  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
simvastatin  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
streptozocin  (EXP,ISO)
superoxide  (ISO)
tamoxifen  (ISO)
tetrachloromethane  (EXP,ISO)
tetraphene  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trimellitic anhydride  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)
Y-27632  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
axon extension  (IEA,ISO)
basement membrane organization  (IEA,ISO)
bicellular tight junction assembly  (IMP)
calcium-independent cell-matrix adhesion  (ISO)
cardiac muscle cell differentiation  (IEA,ISO)
cardiac muscle tissue development  (ISO)
CD40 signaling pathway  (IEA,ISO)
cell adhesion  (ISO)
cell adhesion mediated by integrin  (IBA,IGI,ISO,ISS)
cell fate specification  (IEA,ISO)
cell migration  (IBA,ISO)
cell migration involved in sprouting angiogenesis  (IEA,ISO)
cell projection organization  (IMP)
cell-cell adhesion mediated by integrin  (IEA,ISO)
cell-matrix adhesion  (IBA,IEA,ISO)
cell-substrate adhesion  (ISO)
cellular response to ionizing radiation  (IEP)
cellular response to low-density lipoprotein particle stimulus  (IEA,ISO,ISS)
cellular response to mechanical stimulus  (IEP)
cellular response to vitamin D  (IEP)
dendrite morphogenesis  (IEA,ISO)
establishment of mitotic spindle orientation  (IEA,ISO)
establishment of Sertoli cell barrier  (IEP)
formation of radial glial scaffolds  (IEA,ISO)
G1/S transition of mitotic cell cycle  (IEA,ISO)
germ cell migration  (IEA,ISO)
heterotypic cell-cell adhesion  (IEA,ISO)
in utero embryonic development  (IEA,ISO)
integrin-mediated signaling pathway  (IBA,IEA,IMP,ISO)
lamellipodium assembly  (IMP)
leukocyte cell-cell adhesion  (ISO)
leukocyte tethering or rolling  (IEA,ISO)
maternal process involved in female pregnancy  (IEP)
mesodermal cell differentiation  (IEA,ISO)
modulation of chemical synaptic transmission  (ISO)
negative regulation of anoikis  (IEA,ISO)
negative regulation of apoptotic process  (IDA)
negative regulation of cell differentiation  (IEA,ISO)
negative regulation of cell population proliferation  (IMP)
negative regulation of cell projection organization  (IMP)
negative regulation of neuron differentiation  (IMP)
negative regulation of Rho protein signal transduction  (IEA,ISO)
neuron projection development  (ISO)
phagocytosis  (IMP)
positive regulation of angiogenesis  (IEA,ISO)
positive regulation of apoptotic process  (ISO)
positive regulation of cell migration  (IMP)
positive regulation of cell population proliferation  (IEA,ISO)
positive regulation of cell-substrate adhesion  (IMP)
positive regulation of endocytosis  (IMP)
positive regulation of fibroblast migration  (IEA,ISO)
positive regulation of glutamate uptake involved in transmission of nerve impulse  (IEA,ISO)
positive regulation of GTPase activity  (IEA,ISO)
positive regulation of neuron differentiation  (IMP)
positive regulation of neuron projection development  (IMP)
positive regulation of peptidyl-tyrosine phosphorylation  (IMP)
positive regulation of protein kinase B signaling  (IEA,ISO)
positive regulation of protein localization to plasma membrane  (IEA,ISO,ISS)
positive regulation of signaling receptor activity  (IEA,ISO)
positive regulation of wound healing  (IEA,ISO)
protein transport within lipid bilayer  (IMP)
reactive gliosis  (IEA,ISO)
receptor internalization  (IEA,ISO,ISS)
regulation of cell cycle  (IEA,ISO)
regulation of collagen catabolic process  (IEA,ISO,ISS)
regulation of G protein-coupled receptor signaling pathway  (IMP)
regulation of inward rectifier potassium channel activity  (IEA,ISO)
regulation of spontaneous synaptic transmission  (IEA,ISO)
response to activity  (IEP)
response to drug  (IEP)
response to gonadotropin  (IEP)
response to nutrient levels  (IEP)
response to transforming growth factor beta  (IEP)
sarcomere organization  (IEA,ISO)
stress fiber assembly  (ISO)
synaptic membrane adhesion to extracellular matrix  (IC)
tissue homeostasis  (IMP)
transforming growth factor beta receptor signaling pathway  (ISO)
visual learning  (IEA,ISO)

References

References - curated
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Additional References at PubMed
PMID:1715889   PMID:1833411   PMID:1839357   PMID:7544313   PMID:8306881   PMID:8601592   PMID:9004034   PMID:9415431   PMID:9553049   PMID:10079228   PMID:10455171   PMID:11732910  
PMID:11792823   PMID:11869556   PMID:12189152   PMID:12417594   PMID:12477932   PMID:12509413   PMID:12591243   PMID:12642506   PMID:12651615   PMID:12670870   PMID:12697723   PMID:12807887  
PMID:12869515   PMID:12879062   PMID:12904471   PMID:12957148   PMID:14522949   PMID:14550305   PMID:14559243   PMID:14660602   PMID:14715956   PMID:14970227   PMID:15006356   PMID:15056720  
PMID:15174102   PMID:15189273   PMID:15366013   PMID:15618357   PMID:15705967   PMID:15811857   PMID:16148033   PMID:16424942   PMID:16459165   PMID:16467530   PMID:16554304   PMID:16557522  
PMID:16608848   PMID:16750664   PMID:16783488   PMID:16803572   PMID:16935002   PMID:17065460   PMID:17099249   PMID:17123509   PMID:17158881   PMID:17583725   PMID:17593555   PMID:17598176  
PMID:17665129   PMID:17704059   PMID:18037995   PMID:18156211   PMID:18188865   PMID:18245559   PMID:18308860   PMID:18333785   PMID:18573216   PMID:18611855   PMID:18778724   PMID:18922173  
PMID:19056867   PMID:19215949   PMID:19234460   PMID:19364818   PMID:19487454   PMID:19581412   PMID:19651211   PMID:19703720   PMID:19933311   PMID:19946888   PMID:20019333   PMID:20049771  
PMID:20103531   PMID:20183869   PMID:20213330   PMID:20237282   PMID:20563599   PMID:20810886   PMID:21136191   PMID:21149578   PMID:21178109   PMID:21185282   PMID:21310825   PMID:21423176  
PMID:21508095   PMID:21593411   PMID:21620958   PMID:21696820   PMID:21738954   PMID:21747167   PMID:21932337   PMID:22198504   PMID:22357865   PMID:22413019   PMID:22659335   PMID:22664869  
PMID:22692550   PMID:22812390   PMID:22865233   PMID:22890232   PMID:23023225   PMID:23058350   PMID:23118988   PMID:23125415   PMID:23154389   PMID:23238717   PMID:23297403   PMID:23325413  
PMID:23376485   PMID:23382103   PMID:23382219   PMID:23395392   PMID:23468528   PMID:23533145   PMID:23620790   PMID:23658023   PMID:23659290   PMID:23715271   PMID:23755149   PMID:23981064  
PMID:24036928   PMID:24044949   PMID:24122940   PMID:24220332   PMID:24472554   PMID:24535659   PMID:24681597   PMID:24742749   PMID:24823363   PMID:25063885   PMID:25098415   PMID:25220424  
PMID:25300309   PMID:25336636   PMID:25468996   PMID:25713411   PMID:25715677   PMID:25716834   PMID:25754303   PMID:25911094   PMID:25974241   PMID:26093969   PMID:26143257   PMID:26316108  
PMID:26335442   PMID:26467923   PMID:26520903   PMID:26763945   PMID:26997644   PMID:27169768   PMID:27879672   PMID:28176845   PMID:28760342   PMID:28765893   PMID:29023021   PMID:29162887  
PMID:29223350   PMID:29237506   PMID:29324307   PMID:29599211   PMID:30121936   PMID:30206251   PMID:30992345   PMID:31096970   PMID:31331973   PMID:31699892  


Genomics

Comparative Map Data
Itgb1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21956,705,123 - 56,753,199 (+)NCBI
Rnor_6.0 Ensembl1961,677,542 - 61,725,535 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01961,677,512 - 61,725,537 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01972,324,582 - 72,372,325 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41958,600,095 - 58,647,531 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11958,605,791 - 58,652,463 (-)NCBI
Celera1956,037,604 - 56,085,651 (+)NCBICelera
Cytogenetic Map19q12NCBI
ITGB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1032,887,273 - 33,005,792 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl1032,900,318 - 33,005,792 (-)EnsemblGRCh38hg38GRCh38
GRCh381032,900,318 - 32,958,230 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371033,189,246 - 33,247,158 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361033,229,326 - 33,287,204 (-)NCBINCBI36hg18NCBI36
Build 341033,236,244 - 33,264,492NCBI
Celera1032,954,580 - 33,012,639 (-)NCBI
Cytogenetic Map10p11.22NCBI
HuRef1032,908,756 - 32,966,834 (-)NCBIHuRef
CHM1_11033,190,855 - 33,248,907 (-)NCBICHM1_1
Itgb1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398129,412,135 - 129,460,060 (+)NCBIGRCm39mm39
GRCm39 Ensembl8129,412,135 - 129,459,681 (+)Ensembl
GRCm388128,685,654 - 128,733,579 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8128,685,654 - 128,733,200 (+)EnsemblGRCm38mm10GRCm38
MGSCv378131,209,554 - 131,257,479 (+)NCBIGRCm37mm9NCBIm37
MGSCv368131,571,871 - 131,619,287 (+)NCBImm8
Celera8133,002,434 - 133,050,263 (+)NCBICelera
Cytogenetic Map8E2NCBI
Itgb1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554624,454,809 - 4,484,842 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554624,454,809 - 4,483,227 (+)NCBIChiLan1.0ChiLan1.0
ITGB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11033,608,978 - 33,662,258 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1033,608,978 - 33,644,031 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01033,023,573 - 33,081,384 (-)NCBIMhudiblu_PPA_v0panPan3
ITGB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.123,728,472 - 3,757,696 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl23,670,596 - 3,756,961 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha23,811,003 - 3,857,059 (+)NCBI
ROS_Cfam_1.024,006,817 - 4,053,107 (+)NCBI
UMICH_Zoey_3.123,785,306 - 3,831,383 (+)NCBI
UNSW_CanFamBas_1.023,819,236 - 3,865,356 (+)NCBI
UU_Cfam_GSD_1.023,939,078 - 3,985,170 (+)NCBI
Itgb1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934411,966,401 - 11,996,275 (-)NCBI
SpeTri2.0NW_0049365741,465,981 - 1,495,717 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ITGB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1056,078,398 - 56,173,795 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11056,078,393 - 56,130,608 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21061,450,695 - 61,502,941 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ITGB1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1932,201,030 - 32,258,247 (-)NCBI
ChlSab1.1 Ensembl932,202,204 - 32,258,154 (-)Ensembl
Itgb1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248058,748,848 - 8,800,259 (+)NCBI

Position Markers
Itgb1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21956,744,391 - 56,745,956 (+)MAPPER
Rnor_6.01961,716,730 - 61,718,294NCBIRnor6.0
Rnor_5.01972,363,518 - 72,365,082UniSTSRnor5.0
RGSC_v3.41958,607,339 - 58,608,903UniSTSRGSC3.4
Celera1956,076,843 - 56,078,407UniSTS
Cytogenetic Map19q12UniSTS
AU048052  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21956,741,837 - 56,741,996 (+)MAPPER
Rnor_6.01961,714,176 - 61,714,334NCBIRnor6.0
Rnor_5.01972,360,964 - 72,361,122UniSTSRnor5.0
RGSC_v3.41958,611,298 - 58,611,456UniSTSRGSC3.4
Celera1956,074,289 - 56,074,447UniSTS
Cytogenetic Map19q12UniSTS
RH138141  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21956,705,988 - 56,706,174 (+)MAPPER
Rnor_6.01961,678,326 - 61,678,511NCBIRnor6.0
Rnor_5.01972,325,396 - 72,325,581UniSTSRnor5.0
RGSC_v3.41958,646,562 - 58,646,747UniSTSRGSC3.4
Celera1956,038,388 - 56,038,573UniSTS
Cytogenetic Map19q12UniSTS
UniSTS:256618  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21956,744,391 - 56,745,956 (+)MAPPER
Rnor_6.01961,716,730 - 61,718,294NCBIRnor6.0
Rnor_5.01972,363,518 - 72,365,082UniSTSRnor5.0
RGSC_v3.41958,607,339 - 58,608,903UniSTSRGSC3.4
Celera1956,076,843 - 56,078,407UniSTS
Cytogenetic Map19q12UniSTS
Itgb1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21956,744,518 - 56,746,039 (+)MAPPER
Rnor_6.01961,716,857 - 61,718,377NCBIRnor6.0
Rnor_5.01972,363,645 - 72,365,165UniSTSRnor5.0
RGSC_v3.41958,607,256 - 58,608,776UniSTSRGSC3.4
Celera1956,076,970 - 56,078,490UniSTS
Cytogenetic Map19q12UniSTS
Itgb1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21956,752,981 - 56,753,153 (+)MAPPER
Rnor_6.01961,725,320 - 61,725,491NCBIRnor6.0
Rnor_5.01972,372,108 - 72,372,279UniSTSRnor5.0
RGSC_v3.41958,600,141 - 58,600,312UniSTSRGSC3.4
Celera1956,085,434 - 56,085,605UniSTS
Cytogenetic Map19q12UniSTS
Itgb1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21956,752,911 - 56,753,152 (+)MAPPER
Rnor_6.01961,725,250 - 61,725,490NCBIRnor6.0
Rnor_5.01972,372,038 - 72,372,278UniSTSRnor5.0
RGSC_v3.41958,600,142 - 58,600,382UniSTSRGSC3.4
Celera1956,085,364 - 56,085,604UniSTS
Cytogenetic Map19q12UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19243296362275575Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)191899398262275575Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)191917749562275575Rat
2298478Eau8Experimental allergic uveoretinitis QTL 80.0163uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)192140778762275575Rat
61350Bp32Blood pressure QTL 320.012arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)192481825762275575Rat
724546Kidm3Kidney mass QTL 33.1kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)193299439262275575Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:565
Count of miRNA genes:275
Interacting mature miRNAs:327
Transcripts:ENSRNOT00000014785
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 40 11 8
Low 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000014785   ⟹   ENSRNOP00000014785
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1961,677,542 - 61,725,535 (+)Ensembl
RefSeq Acc Id: NM_017022   ⟹   NP_058718
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21956,705,205 - 56,753,199 (+)NCBI
Rnor_6.01961,677,542 - 61,725,537 (+)NCBI
Rnor_5.01972,324,582 - 72,372,325 (+)NCBI
RGSC_v3.41958,600,095 - 58,647,531 (-)RGD
Celera1956,037,604 - 56,085,651 (+)RGD
Sequence:
RefSeq Acc Id: XM_006255824   ⟹   XP_006255886
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21956,705,123 - 56,753,199 (+)NCBI
Rnor_6.01961,677,512 - 61,725,537 (+)NCBI
Rnor_5.01972,324,582 - 72,372,325 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_058718 (Get FASTA)   NCBI Sequence Viewer  
  XP_006255886 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA86669 (Get FASTA)   NCBI Sequence Viewer  
  AAI31846 (Get FASTA)   NCBI Sequence Viewer  
  EDL96787 (Get FASTA)   NCBI Sequence Viewer  
  P49134 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_058718   ⟸   NM_017022
- Peptide Label: precursor
- UniProtKB: P49134 (UniProtKB/Swiss-Prot),   A0A0G2JSK5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006255886   ⟸   XM_006255824
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000014785   ⟸   ENSRNOT00000014785
Protein Domains
INB   Integrin_b_cyt   Integrin_B_tail   PSI   VWFA

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701260
Promoter ID:EPDNEW_R11783
Type:initiation region
Name:Itgb1_1
Description:integrin subunit beta 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01961,677,508 - 61,677,568EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2927 AgrOrtholog
Ensembl Genes ENSRNOG00000010966 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000014785 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000014785 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.410 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:8366766 IMAGE-MGC_LOAD
InterPro EGF_extracell UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  I-EGF_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Integrin_beta-1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Integrin_beta_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Integrin_bsu UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Integrin_bsu_cyt_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Integrin_bsu_tail UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Integrin_bsu_tail_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Integrin_bsu_VWA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Integrin_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PSI UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  vWFA_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:24511 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:156664 IMAGE-MGC_LOAD
NCBI Gene 24511 ENTREZGENE
PANTHER PTHR10082 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10082:SF28 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam EGF_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  I-EGF_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Integrin_b_cyt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Integrin_B_tail UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Integrin_beta UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PSI_integrin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Itgb1 PhenoGen
PIRSF Integrin_B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS INTEGRINB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE EGF_1 UniProtKB/Swiss-Prot
  INTEGRIN_BETA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART INB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Integrin_b_cyt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Integrin_B_tail UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PSI UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF53300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF69179 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF69687 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JSK5 ENTREZGENE, UniProtKB/TrEMBL
  ITB1_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary A2RRT8 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Itgb1  integrin subunit beta 1  LOC102556297  collagen alpha-1(I) chain-like  Data Merged 737654 PROVISIONAL
2015-12-23 Itgb1  integrin subunit beta 1  Itgb1  integrin, beta 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-12-18 LOC102556297  collagen alpha-1(I) chain-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2009-12-15 Itgb1  integrin, beta 1  Itgb1  integrin beta 1 (fibronectin receptor beta)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-11-17 Itgb1  integrin beta 1 (fibronectin receptor beta)      Name updated 1299863 APPROVED
2002-06-10 Itgb1  Integrin, beta 1      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in fibroblasts and inflammatory cells 633129
gene_process may be involved in inflammation and fibrosis 633129