Gene: Tln1 (talin 1) Rattus norvegicus
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Symbol: Tln1
Name: talin 1
Description: ENCODES a protein that exhibits integrin binding; LIM domain binding (ortholog); phosphatidylinositol binding (ortholog); INVOLVED IN cell-substrate junction assembly (ortholog); cortical actin cytoskeleton organization (ortholog); integrin activation (ortholog); PARTICIPATES IN epidermal growth factor/neuregulin signaling pathway; integrin mediated signaling pathway; ASSOCIATED WITH anauxetic dysplasia 1 (ortholog); autosomal recessive distal spinal muscular atrophy 2 (ortholog); Hyperphosphatasia with Mental Retardation Syndrome 2 (ortholog); FOUND IN focal adhesion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cadmium dichloride
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC313494; MGC116305; talin; talin-1; Tln
Orthologs:
Homo sapiens (human) : TLN1 (talin 1)  HGNC  Alliance
Mus musculus (house mouse) : Tln1 (talin 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tln1 (talin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TLN1 (talin 1)
Canis lupus familiaris (dog) : TLN1 (talin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tln1 (talin 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0559,033,635 - 59,063,592 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0563,558,230 - 63,588,186 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4560,010,952 - 60,040,908 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1560,011,137 - 60,040,820 (-)NCBI
Celera556,368,517 - 56,398,472 (-)NCBICelera
Cytogenetic Map5q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Tln1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1306247
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-01-08
Status: ACTIVE