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Gene: Itgb1 (integrin beta 1 (fibronectin receptor beta)) Mus musculus
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Symbol: Itgb1
Name: integrin beta 1 (fibronectin receptor beta)
Description: Exhibits integrin binding activity. Contributes to laminin binding activity. Involved in several processes, including cell migration involved in sprouting angiogenesis; cell morphogenesis involved in differentiation; and striated muscle cell differentiation. Localizes to several cellular components, including the Schaffer collateral - CA1 synapse; integral component of plasma membrane; and myelin sheath abaxonal region. Colocalizes with the cytoplasmic vesicle and perinuclear region of cytoplasm. Used to study Hirschsprung's disease. Is expressed in several structures, including alimentary system; brain; genitourinary system; heart; and limb. Orthologous to human ITGB1 (integrin subunit beta 1); PARTICIPATES IN integrin mediated signaling pathway; Reelin signaling pathway; syndecan signaling pathway; INTERACTS WITH (+)-pilocarpine; 17beta-hydroxy-5alpha-androstan-3-one; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4633401G24Rik; AA409975; AA960159; CD29; ENSMUSG00000051907; fibronectin receptor subunit beta; Fnrb; Gm9863; gpIIa; integrin beta-1; VLA-4 subunit beta
Orthologs:
Homo sapiens (human) : ITGB1 (integrin subunit beta 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Itgb1 (integrin subunit beta 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Itgb1 (integrin subunit beta 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ITGB1 (integrin subunit beta 1)
Canis lupus familiaris (dog) : ITGB1 (integrin subunit beta 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Itgb1 (integrin subunit beta 1)
Sus scrofa (pig) : ITGB1 (integrin subunit beta 1)
Chlorocebus sabaeus (African green monkey) : ITGB1 (integrin subunit beta 1)
Heterocephalus glaber (naked mole-rat) : Itgb1 (integrin subunit beta 1)
more info ...
Related Pseudogenes: Gm18928  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl8128,685,654 - 128,733,200 (+)Ensembl
GRCm388128,685,654 - 128,733,579 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv378131,209,554 - 131,257,479 (+)NCBIGRCm37mm9NCBIm37
MGSCv368131,571,871 - 131,619,287 (+)NCBImm8
Celera8133,002,434 - 133,050,263 (+)NCBICelera
Cytogenetic Map8E2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Itgb1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733764
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-02-11
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.