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Gene: Itgb1 (integrin beta 1 (fibronectin receptor beta)) Mus musculus
Symbol: Itgb1
Name: integrin beta 1 (fibronectin receptor beta)
Description: Exhibits integrin binding activity. Contributes to laminin binding activity. Involved in several processes, including cell migration involved in sprouting angiogenesis; cell morphogenesis involved in differentiation; and striated muscle cell differentiation. Localizes to several cellular components, including the Schaffer collateral - CA1 synapse; integral component of plasma membrane; and myelin sheath abaxonal region. Colocalizes with the cytoplasmic vesicle and perinuclear region of cytoplasm. Used to study Hirschsprung's disease. Is expressed in several structures, including alimentary system; brain; genitourinary system; heart; and limb. Orthologous to human ITGB1 (integrin subunit beta 1); PARTICIPATES IN integrin mediated signaling pathway; Reelin signaling pathway; syndecan signaling pathway; INTERACTS WITH (+)-pilocarpine; 17beta-hydroxy-5alpha-androstan-3-one; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4633401G24Rik; AA409975; AA960159; CD29; ENSMUSG00000051907; fibronectin receptor subunit beta; Fnrb; Gm9863; gpIIa; integrin beta-1; VLA-4 subunit beta
Homo sapiens (human) : ITGB1 (integrin subunit beta 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Itgb1 (integrin subunit beta 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Itgb1 (integrin subunit beta 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ITGB1 (integrin subunit beta 1)
Canis lupus familiaris (dog) : ITGB1 (integrin subunit beta 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Itgb1 (integrin subunit beta 1)
Sus scrofa (pig) : ITGB1 (integrin subunit beta 1)
Chlorocebus sabaeus (African green monkey) : ITGB1 (integrin subunit beta 1)
Heterocephalus glaber (naked mole-rat) : Itgb1 (integrin subunit beta 1)
more info ...
Related Pseudogenes: Gm18928  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl8128,685,654 - 128,733,200 (+)Ensembl
GRCm388128,685,654 - 128,733,579 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv378131,209,554 - 131,257,479 (+)NCBIGRCm37mm9NCBIm37
MGSCv368131,571,871 - 131,619,287 (+)NCBImm8
Celera8133,002,434 - 133,050,263 (+)NCBICelera
Cytogenetic Map8E2NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Itgb1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733764
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-02-11
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.