ITGB1 (integrin subunit beta 1) - Rat Genome Database

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Gene: ITGB1 (integrin subunit beta 1) Homo sapiens
Analyze
Symbol: ITGB1
Name: integrin subunit beta 1
RGD ID: 736631
HGNC Page HGNC
Description: Enables several functions, including collagen binding activity involved in cell-matrix adhesion; enzyme binding activity; and fibronectin binding activity. Contributes to C-X3-C chemokine binding activity. Involved in several processes, including cell surface receptor signaling pathway; cell-cell adhesion mediated by integrin; and regulation of signal transduction. Acts upstream of or within calcium-independent cell-matrix adhesion and positive regulation of apoptotic process. Located in several cellular components, including filopodium; neuromuscular junction; and sarcolemma. Part of integrin complex. Colocalizes with focal adhesion; perinuclear region of cytoplasm; and ruffle membrane. Biomarker of lung non-small cell carcinoma and lung small cell carcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CD29; fibronectin receptor beta subunit; fibronectin receptor subunit beta; FNRB; glycoprotein IIa; GPIIA; integrin beta 1; integrin beta-1; integrin VLA-4 beta subunit; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12); MDF2; MSK12; very late activation protein, beta polypeptide; VLA-4 subunit beta; VLA-BETA; VLAB
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: ITGB1P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1032,887,273 - 33,005,792 (-)EnsemblGRCh38hg38GRCh38
GRCh381032,900,318 - 32,958,230 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371033,189,246 - 33,247,158 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361033,229,326 - 33,287,204 (-)NCBINCBI36hg18NCBI36
Build 341033,236,244 - 33,264,492NCBI
Celera1032,954,580 - 33,012,639 (-)NCBI
Cytogenetic Map10p11.22NCBI
HuRef1032,908,756 - 32,966,834 (-)NCBIHuRef
CHM1_11033,190,855 - 33,248,907 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-pilocarpine  (ISO)
(20S)-ginsenoside Rh1  (EXP)
(24S)-24-hydroxycholesterol  (EXP)
(25R)-cholest-5-ene-3beta,26-diol  (EXP)
(R)-adrenaline  (ISO)
(R)-mevalonic acid  (EXP,ISO)
(S)-nicotine  (EXP)
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1,3-dinitrobenzene  (ISO)
1-naphthyl isothiocyanate  (ISO)
17beta-estradiol  (EXP)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (EXP)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-D  (ISO)
2,4-dinitrotoluene  (ISO)
2,5-hexanedione  (ISO)
2,6-dinitrotoluene  (ISO)
2-deoxy-D-glucose  (EXP)
2-methoxyethanol  (ISO)
2-nitrotoluene  (ISO)
26-hydroxycholesterol  (EXP)
3',5'-cyclic AMP  (ISO)
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (EXP,ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
5-azacytidine  (EXP)
7alpha-hydroxycholesterol  (EXP)
aflatoxin B1  (EXP)
aldehydo-D-glucose  (EXP,ISO)
all-trans-retinoic acid  (EXP,ISO)
all-trans-retinol  (EXP)
aluminium oxide  (EXP)
ammonium chloride  (ISO)
antirheumatic drug  (EXP)
aristolochic acid  (EXP)
Aroclor 1254  (ISO)
arsane  (EXP)
arsenic atom  (EXP)
arsenous acid  (EXP)
artesunate  (EXP)
atorvastatin calcium  (EXP,ISO)
atrazine  (EXP)
aucubin  (EXP)
beauvericin  (EXP)
benomyl  (EXP)
benzo[a]pyrene  (EXP,ISO)
beta-carotene  (EXP)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
blebbistatin  (EXP)
bromochloroacetic acid  (ISO)
bucladesine  (EXP)
C.I. Natural Red 20  (EXP)
cadmium atom  (EXP)
cadmium dichloride  (EXP,ISO)
calciol  (ISO)
carbamazepine  (EXP)
carbendazim  (EXP)
carbon nanotube  (ISO)
carmustine  (EXP)
chloroacetaldehyde  (EXP)
chloropicrin  (EXP)
chrysene  (ISO)
cidofovir anhydrous  (EXP)
cisplatin  (EXP)
cocaine  (ISO)
colforsin daropate hydrochloride  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (EXP)
crocidolite asbestos  (ISO)
curcumin  (EXP)
cyclosporin A  (EXP)
D-glucose  (EXP,ISO)
DDT  (EXP)
dexamethasone  (ISO)
dextran sulfate  (ISO)
diallyl trisulfide  (EXP)
diarsenic trioxide  (EXP)
dibenzo[a,l]pyrene  (EXP)
dibutyl phthalate  (ISO)
dichlorine  (ISO)
diclofenac  (EXP)
dicrotophos  (EXP)
dimethylarsinic acid  (ISO)
dioxygen  (EXP,ISO)
disulfiram  (EXP)
diuron  (ISO)
dobutamine  (ISO)
doxorubicin  (EXP)
endosulfan  (ISO)
enniatin  (EXP)
erlotinib hydrochloride  (ISO)
ethanol  (ISO)
ethyl trans-caffeate  (EXP)
etodolac  (EXP)
eugenol  (EXP)
fenamidone  (ISO)
fenhexamid  (EXP)
fenofibrate  (ISO)
folic acid  (EXP,ISO)
fructose  (EXP)
fulvestrant  (EXP)
furan  (ISO)
gefitinib  (EXP)
genistein  (EXP,ISO)
geranylgeraniol  (EXP,ISO)
ginsenoside C-K  (EXP)
glucose  (EXP,ISO)
glyphosate  (EXP)
hydrogen peroxide  (EXP)
hydroquinone  (EXP,ISO)
ifosfamide  (EXP)
isoprenaline  (ISO)
ivermectin  (EXP)
latrunculin A  (EXP)
lead diacetate  (ISO)
lipopolysaccharide  (ISO)
lithocholic acid  (EXP)
lovastatin  (ISO)
magnesium atom  (EXP)
manganese atom  (ISO)
manganese(0)  (ISO)
medroxyprogesterone acetate  (EXP)
mercury atom  (ISO)
mercury(0)  (ISO)
metformin  (ISO)
methotrexate  (EXP)
methyl methanesulfonate  (EXP)
methylseleninic acid  (ISO)
ML-7  (EXP)
monocrotaline  (ISO)
morusin  (EXP)
N-acetyl-L-cysteine  (EXP)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (ISO)
nicotine  (EXP)
notoginsenoside R1  (ISO)
ozone  (ISO)
paclitaxel  (ISO)
paracetamol  (ISO)
pentane-2,3-dione  (ISO)
phenobarbital  (ISO)
phenytoin  (EXP)
picoxystrobin  (EXP)
pirinixic acid  (ISO)
potassium iodide  (ISO)
pravastatin  (EXP,ISO)
progesterone  (ISO)
prostaglandin E2  (ISO)
quercetin  (EXP,ISO)
quercitrin  (EXP)
raloxifene  (EXP)
resveratrol  (EXP,ISO)
rimonabant  (ISO)
rotenone  (EXP)
SB 431542  (EXP)
Shikonin  (EXP)
silver atom  (ISO)
silver(0)  (ISO)
simvastatin  (EXP)
sodium arsenate  (ISO)
sodium arsenite  (EXP,ISO)
Soman  (ISO)
streptozocin  (ISO)
superoxide  (ISO)
tamoxifen  (EXP)
temozolomide  (EXP)
tetrachloromethane  (ISO)
tetraphene  (ISO)
thioacetamide  (ISO)
titanium dioxide  (ISO)
trimellitic anhydride  (ISO)
tunicamycin  (ISO)
valproic acid  (EXP)
vancomycin  (ISO)
vinclozolin  (ISO)
vorinostat  (EXP)
Y-27632  (EXP)
zinc atom  (EXP)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
axon extension  (IEA,ISO)
B cell differentiation  (IC)
basement membrane organization  (IEA)
bicellular tight junction assembly  (ISO)
calcium-independent cell-matrix adhesion  (IGI)
cardiac muscle cell differentiation  (IEA,ISO)
cardiac muscle tissue development  (ISO)
CD40 signaling pathway  (IDA)
cell adhesion  (IDA)
cell adhesion mediated by integrin  (IBA,IDA,ISS)
cell fate specification  (IEA,ISO)
cell migration  (IBA,ISO,TAS)
cell migration involved in sprouting angiogenesis  (IEA,ISO)
cell projection organization  (ISS)
cell-cell adhesion mediated by integrin  (IEP)
cell-matrix adhesion  (IBA,IEA,IMP,ISO)
cell-substrate adhesion  (IMP)
cellular defense response  (TAS)
cellular response to ionizing radiation  (ISO)
cellular response to low-density lipoprotein particle stimulus  (ISS)
cellular response to mechanical stimulus  (ISO)
cellular response to vitamin D  (ISO)
dendrite morphogenesis  (IEA,ISO)
establishment of mitotic spindle orientation  (IMP)
establishment of Sertoli cell barrier  (ISO)
formation of radial glial scaffolds  (IEA,ISO)
G1/S transition of mitotic cell cycle  (IEA,ISO)
germ cell migration  (IEA,ISO)
heterotypic cell-cell adhesion  (IMP)
homophilic cell adhesion via plasma membrane adhesion molecules  (TAS)
in utero embryonic development  (IEA,ISO)
integrin-mediated signaling pathway  (IBA,IDA,IEA,IMP)
lamellipodium assembly  (ISS)
leukocyte cell-cell adhesion  (IDA)
leukocyte tethering or rolling  (IMP)
maintenance of blood-brain barrier  (NAS)
maternal process involved in female pregnancy  (ISO)
mesodermal cell differentiation  (IEP)
modulation of chemical synaptic transmission  (ISO)
negative regulation of anoikis  (IMP)
negative regulation of apoptotic process  (ISO)
negative regulation of cell differentiation  (IEA,ISO)
negative regulation of cell population proliferation  (ISO)
negative regulation of cell projection organization  (ISO)
negative regulation of neuron differentiation  (ISO)
negative regulation of Rho protein signal transduction  (IEA,ISO)
neuron projection development  (ISO)
phagocytosis  (ISS)
positive regulation of angiogenesis  (IMP)
positive regulation of apoptotic process  (IGI)
positive regulation of cell migration  (ISO,ISS)
positive regulation of cell population proliferation  (IEA,ISO)
positive regulation of cell-substrate adhesion  (ISO)
positive regulation of endocytosis  (ISO)
positive regulation of fibroblast migration  (IDA)
positive regulation of glutamate uptake involved in transmission of nerve impulse  (ISS)
positive regulation of GTPase activity  (IMP)
positive regulation of neuron differentiation  (ISO)
positive regulation of neuron projection development  (ISO)
positive regulation of peptidyl-tyrosine phosphorylation  (ISO)
positive regulation of protein kinase B signaling  (IDA)
positive regulation of protein localization to plasma membrane  (IDA)
positive regulation of signaling receptor activity  (IDA)
positive regulation of wound healing  (IDA)
protein transport within lipid bilayer  (ISO)
reactive gliosis  (ISS)
receptor internalization  (ISS)
regulation of cell cycle  (IEA,ISO)
regulation of collagen catabolic process  (IDA)
regulation of G protein-coupled receptor signaling pathway  (ISO)
regulation of inward rectifier potassium channel activity  (ISS)
regulation of spontaneous synaptic transmission  (ISS)
response to activity  (ISO)
response to gonadotropin  (ISO)
response to nutrient levels  (ISO)
response to transforming growth factor beta  (ISO)
response to xenobiotic stimulus  (ISO)
sarcomere organization  (IEA,ISO)
stress fiber assembly  (IMP)
tissue homeostasis  (ISO)
transforming growth factor beta receptor signaling pathway  (IMP)
viral entry into host cell  (IEA)
visual learning  (IEA,ISO)

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

Additional References at PubMed
PMID:1542691   PMID:1551917   PMID:1690718   PMID:1693624   PMID:1715889   PMID:2116421   PMID:2138612   PMID:2156854   PMID:2202737   PMID:2249781   PMID:2524991   PMID:2527614  
PMID:2572537   PMID:2649503   PMID:2958481   PMID:2967289   PMID:3546305   PMID:7504269   PMID:7523423   PMID:7539135   PMID:7541634   PMID:7544298   PMID:7545396   PMID:7559467  
PMID:7592829   PMID:7657702   PMID:7681433   PMID:7690138   PMID:7768999   PMID:8020569   PMID:8120056   PMID:8163531   PMID:8245132   PMID:8387021   PMID:8428973   PMID:8444890  
PMID:8537347   PMID:8538749   PMID:8567725   PMID:8630057   PMID:8649427   PMID:8757325   PMID:8757349   PMID:8757599   PMID:8798654   PMID:8831898   PMID:8838570   PMID:8889548  
PMID:9117345   PMID:9281591   PMID:9281592   PMID:9295027   PMID:9360995   PMID:9360996   PMID:9415431   PMID:9425259   PMID:9431988   PMID:9442085   PMID:9494094   PMID:9501082  
PMID:9517988   PMID:9547293   PMID:9552005   PMID:9565552   PMID:9614184   PMID:9645947   PMID:9660880   PMID:9685391   PMID:9686320   PMID:9688542   PMID:9722563   PMID:9736715  
PMID:9812906   PMID:9813091   PMID:9889149   PMID:9914169   PMID:9916748   PMID:10065872   PMID:10201960   PMID:10209034   PMID:10229664   PMID:10388537   PMID:10397731   PMID:10397733  
PMID:10455171   PMID:10459022   PMID:10464311   PMID:10486209   PMID:10506186   PMID:10593924   PMID:10604475   PMID:10613898   PMID:10623819   PMID:10673366   PMID:10676904   PMID:10684262  
PMID:10694273   PMID:10734060   PMID:10741407   PMID:10778855   PMID:10804218   PMID:10811835   PMID:10852818   PMID:10906324   PMID:10944199   PMID:10944520   PMID:10982388   PMID:11010812  
PMID:11054877   PMID:11076863   PMID:11149921   PMID:11208159   PMID:11230166   PMID:11238109   PMID:11256614   PMID:11278623   PMID:11278628   PMID:11278916   PMID:11279249   PMID:11309411  
PMID:11313964   PMID:11358957   PMID:11387256   PMID:11435317   PMID:11462216   PMID:11507094   PMID:11553610   PMID:11668187   PMID:11716783   PMID:11728829   PMID:11741908   PMID:11751905  
PMID:11775028   PMID:11776052   PMID:11779688   PMID:11792823   PMID:11805102   PMID:11807098   PMID:11807099   PMID:11861761   PMID:11882657   PMID:11884516   PMID:11884618   PMID:11888933  
PMID:11893752   PMID:11907260   PMID:11909975   PMID:11914080   PMID:11918217   PMID:11919189   PMID:11931654   PMID:11932920   PMID:11934885   PMID:11941451   PMID:11964076   PMID:11967148  
PMID:11980922   PMID:11981820   PMID:11989791   PMID:11996105   PMID:11997396   PMID:12020426   PMID:12054567   PMID:12070135   PMID:12091396   PMID:12097820   PMID:12114318   PMID:12118253  
PMID:12138200   PMID:12138201   PMID:12140560   PMID:12163503   PMID:12171996   PMID:12174366   PMID:12175627   PMID:12181350   PMID:12181354   PMID:12200131   PMID:12209735   PMID:12218055  
PMID:12221126   PMID:12364323   PMID:12372334   PMID:12372459   PMID:12376466   PMID:12392763   PMID:12393420   PMID:12397374   PMID:12397575   PMID:12411441   PMID:12417594   PMID:12427871  
PMID:12435334   PMID:12445830   PMID:12456677   PMID:12473654   PMID:12477932   PMID:12480921   PMID:12486108   PMID:12496264   PMID:12500944   PMID:12509413   PMID:12514714   PMID:12517798  
PMID:12574205   PMID:12578911   PMID:12592401   PMID:12595495   PMID:12600989   PMID:12606711   PMID:12637511   PMID:12639940   PMID:12639965   PMID:12662928   PMID:12681287   PMID:12682293  
PMID:12694355   PMID:12695522   PMID:12699087   PMID:12724312   PMID:12782621   PMID:12788934   PMID:12791669   PMID:12796480   PMID:12799374   PMID:12803239   PMID:12807887   PMID:12826661  
PMID:12844491   PMID:12865438   PMID:12869515   PMID:12871973   PMID:12883474   PMID:12887919   PMID:12893184   PMID:12893831   PMID:12904899   PMID:12907437   PMID:12909644   PMID:12915563  
PMID:12918102   PMID:12919677   PMID:12931024   PMID:12941630   PMID:12947314   PMID:12954625   PMID:12969374   PMID:12970173   PMID:14502569   PMID:14512423   PMID:14522909   PMID:14525968  
PMID:14532964   PMID:14550305   PMID:14559243   PMID:14559906   PMID:14562042   PMID:14563646   PMID:14602071   PMID:14607975   PMID:14610084   PMID:14612440   PMID:14612932   PMID:14623330  
PMID:14633626   PMID:14645603   PMID:14662754   PMID:14666169   PMID:14671618   PMID:14675422   PMID:14676841   PMID:14679206   PMID:14681217   PMID:14691141   PMID:14699013   PMID:14699139  
PMID:14722085   PMID:14766759   PMID:14963009   PMID:14970227   PMID:14983010   PMID:14998999   PMID:15006356   PMID:15024036   PMID:15070678   PMID:15090462   PMID:15100006   PMID:15117962  
PMID:15156152   PMID:15158122   PMID:15166232   PMID:15171717   PMID:15181153   PMID:15225631   PMID:15226304   PMID:15231747   PMID:15240572   PMID:15247268   PMID:15254262   PMID:15256055  
PMID:15265786   PMID:15276495   PMID:15276642   PMID:15280429   PMID:15292185   PMID:15292257   PMID:15302884   PMID:15304053   PMID:15389531   PMID:15466867   PMID:15466886   PMID:15485856  
PMID:15489336   PMID:15500293   PMID:15507484   PMID:15509657   PMID:15514009   PMID:15522237   PMID:15539082   PMID:15567743   PMID:15572366   PMID:15583842   PMID:15590642   PMID:15611085  
PMID:15633218   PMID:15645131   PMID:15647274   PMID:15647827   PMID:15677332   PMID:15677455   PMID:15684035   PMID:15699160   PMID:15703214   PMID:15713743   PMID:15713750   PMID:15723043  
PMID:15731179   PMID:15737747   PMID:15757908   PMID:15777792   PMID:15795318   PMID:15805105   PMID:15872091   PMID:15878864   PMID:15881415   PMID:15905178   PMID:15919367   PMID:15947241  
PMID:15949469   PMID:15961545   PMID:15978109   PMID:15978110   PMID:15983209   PMID:15987639   PMID:16002725   PMID:16005200   PMID:16043429   PMID:16055535   PMID:16055706   PMID:16076904  
PMID:16099422   PMID:16103120   PMID:16105875   PMID:16113793   PMID:16148152   PMID:16157583   PMID:16195423   PMID:16213489   PMID:16228294   PMID:16247454   PMID:16256741   PMID:16258728  
PMID:16275327   PMID:16301336   PMID:16326706   PMID:16335952   PMID:16341674   PMID:16344560   PMID:16357324   PMID:16363250   PMID:16365170   PMID:16373174   PMID:16381901   PMID:16385340  
PMID:16385451   PMID:16390868   PMID:16415171   PMID:16421008   PMID:16424009   PMID:16430945   PMID:16448724   PMID:16457822   PMID:16459165   PMID:16501085   PMID:16504015   PMID:16510444  
PMID:16537545   PMID:16547007   PMID:16547500   PMID:16569430   PMID:16705158   PMID:16707493   PMID:16731529   PMID:16732726   PMID:16754661   PMID:16754960   PMID:16762342   PMID:16773720  
PMID:16803572   PMID:16807379   PMID:16820945   PMID:16878156   PMID:16882656   PMID:16908668   PMID:16908762   PMID:16916750   PMID:16920332   PMID:16920931   PMID:16940508   PMID:16972245  
PMID:16984420   PMID:17012251   PMID:17015707   PMID:17060328   PMID:17081065   PMID:17110618   PMID:17116465   PMID:17141917   PMID:17158881   PMID:17170699   PMID:17186162   PMID:17286276  
PMID:17300927   PMID:17311314   PMID:17312461   PMID:17318179   PMID:17331499   PMID:17352405   PMID:17371832   PMID:17380111   PMID:17407140   PMID:17408410   PMID:17469136   PMID:17481915  
PMID:17490870   PMID:17498594   PMID:17514628   PMID:17515951   PMID:17521731   PMID:17530710   PMID:17538005   PMID:17560548   PMID:17573778   PMID:17597073   PMID:17603494   PMID:17609118  
PMID:17630833   PMID:17634906   PMID:17638891   PMID:17664272   PMID:17671519   PMID:17690686   PMID:17704059   PMID:17706641   PMID:17726369   PMID:17760843   PMID:17868650   PMID:17888902  
PMID:17899316   PMID:17901052   PMID:17925226   PMID:17960115   PMID:17968567   PMID:17997226   PMID:18026855   PMID:18032709   PMID:18037995   PMID:18048360   PMID:18048918   PMID:18054915  
PMID:18057877   PMID:18155697   PMID:18156211   PMID:18177638   PMID:18186923   PMID:18230652   PMID:18243286   PMID:18250451   PMID:18308860   PMID:18310319   PMID:18322799   PMID:18326820  
PMID:18339839   PMID:18341635   PMID:18356158   PMID:18375753   PMID:18378436   PMID:18383324   PMID:18413316   PMID:18425328   PMID:18425341   PMID:18445685   PMID:18448666   PMID:18462748  
PMID:18477477   PMID:18491034   PMID:18492066   PMID:18499669   PMID:18501656   PMID:18512729   PMID:18519809   PMID:18523483   PMID:18549800   PMID:18554474   PMID:18567578   PMID:18577581  
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PMID:18846341   PMID:18850009   PMID:18940913   PMID:18945876   PMID:18947333   PMID:18957620   PMID:18973153   PMID:18983487   PMID:18984674   PMID:18990704   PMID:18992284   PMID:19005162  
PMID:19020712   PMID:19026687   PMID:19056867   PMID:19057841   PMID:19064571   PMID:19064666   PMID:19073896   PMID:19074826   PMID:19087624   PMID:19115199   PMID:19123990   PMID:19130304  
PMID:19164533   PMID:19168626   PMID:19169646   PMID:19170051   PMID:19176753   PMID:19179533   PMID:19190332   PMID:19228923   PMID:19234460   PMID:19240021   PMID:19250636   PMID:19261610  
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PMID:19646550   PMID:19651211   PMID:19670701   PMID:19679609   PMID:19700757   PMID:19703720   PMID:19710103   PMID:19714342   PMID:19717562   PMID:19724904   PMID:19725119   PMID:19738201  
PMID:19747169   PMID:19752234   PMID:19755493   PMID:19768654   PMID:19775453   PMID:19776755   PMID:19780039   PMID:19796635   PMID:19811096   PMID:19815047   PMID:19822142   PMID:19843520  
PMID:19847290   PMID:19850917   PMID:19885568   PMID:19887442   PMID:19887601   PMID:19889638   PMID:19913121   PMID:19927126   PMID:19930715   PMID:19933311   PMID:19940135   PMID:19946888  
PMID:19960514   PMID:19995941   PMID:20007695   PMID:20051050   PMID:20063417   PMID:20063990   PMID:20075392   PMID:20127017   PMID:20133364   PMID:20145038   PMID:20159608   PMID:20171211  
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PMID:20643357   PMID:20650890   PMID:20650901   PMID:20660204   PMID:20661303   PMID:20678483   PMID:20686611   PMID:20693403   PMID:20713715   PMID:20714794   PMID:20723423   PMID:20725651  
PMID:20800221   PMID:20802515   PMID:20802519   PMID:20811680   PMID:20826546   PMID:20869114   PMID:20877569   PMID:20889506   PMID:20947017   PMID:21045155   PMID:21048156   PMID:21053345  
PMID:21067603   PMID:21071450   PMID:21112327   PMID:21114537   PMID:21119363   PMID:21119598   PMID:21134100   PMID:21134644   PMID:21135504   PMID:21149578   PMID:21170718   PMID:21178109  
PMID:21195710   PMID:21217148   PMID:21255062   PMID:21298552   PMID:21302295   PMID:21310825   PMID:21320503   PMID:21321939   PMID:21325030   PMID:21335239   PMID:21341269   PMID:21344385  
PMID:21357540   PMID:21359179   PMID:21359644   PMID:21363926   PMID:21374738   PMID:21397862   PMID:21400218   PMID:21406228   PMID:21423176   PMID:21426305   PMID:21429937   PMID:21441381  
PMID:21471204   PMID:21474814   PMID:21478906   PMID:21501586   PMID:21521694   PMID:21524887   PMID:21558392   PMID:21567400   PMID:21606500   PMID:21613543   PMID:21618249   PMID:21630092  
PMID:21639857   PMID:21642953   PMID:21647271   PMID:21652699   PMID:21658756   PMID:21691075   PMID:21701559   PMID:21705617   PMID:21732280   PMID:21747167   PMID:21762625   PMID:21772312  
PMID:21784851   PMID:21787362   PMID:21799154   PMID:21806020   PMID:21850018   PMID:21873635   PMID:21876768   PMID:21947080   PMID:21951552   PMID:21961047   PMID:21967109   PMID:21988832  
PMID:22002573   PMID:22015659   PMID:22027826   PMID:22045736   PMID:22100988   PMID:22114305   PMID:22130661   PMID:22136719   PMID:22151306   PMID:22160595   PMID:22178926   PMID:22232555  
PMID:22241990   PMID:22247553   PMID:22266309   PMID:22268729   PMID:22287577   PMID:22298882   PMID:22304920   PMID:22345562   PMID:22349830   PMID:22353524   PMID:22361176   PMID:22370635  
PMID:22374686   PMID:22378044   PMID:22378065   PMID:22382453   PMID:22384145   PMID:22386417   PMID:22388103   PMID:22389402   PMID:22396498   PMID:22402981   PMID:22413019   PMID:22422622  
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PMID:22614033   PMID:22623428   PMID:22627583   PMID:22648170   PMID:22648415   PMID:22711564   PMID:22721769   PMID:22723286   PMID:22734003   PMID:22735632   PMID:22740085   PMID:22810586  
PMID:22829201   PMID:22843693   PMID:22863953   PMID:22865233   PMID:22869523   PMID:22894137   PMID:22898815   PMID:22917688   PMID:22939629   PMID:22940691   PMID:22949126   PMID:22986527  
PMID:22999999   PMID:23007402   PMID:23023061   PMID:23023225   PMID:23069938   PMID:23074279   PMID:23118221   PMID:23125415   PMID:23132859   PMID:23139422   PMID:23148235   PMID:23152803  
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PMID:23359252   PMID:23376485   PMID:23382103   PMID:23382219   PMID:23414517   PMID:23416109   PMID:23436775   PMID:23441154   PMID:23444218   PMID:23455756   PMID:23468528   PMID:23482612  
PMID:23499501   PMID:23522389   PMID:23532895   PMID:23533145   PMID:23536555   PMID:23541832   PMID:23552693   PMID:23558678   PMID:23576567   PMID:23590307   PMID:23595626   PMID:23613949  
PMID:23620790   PMID:23642664   PMID:23658023   PMID:23664187   PMID:23665237   PMID:23677397   PMID:23687274   PMID:23704882   PMID:23709605   PMID:23762436   PMID:23800951   PMID:23819010  
PMID:23857544   PMID:23874206   PMID:23874603   PMID:23883667   PMID:23884246   PMID:23889963   PMID:23925489   PMID:23936390   PMID:23938462   PMID:23951036   PMID:23981064   PMID:23982443  
PMID:23991019   PMID:24004467   PMID:24006483   PMID:24036548   PMID:24036928   PMID:24044949   PMID:24055813   PMID:24056178   PMID:24086451   PMID:24091324   PMID:24112102   PMID:24122451  
PMID:24135056   PMID:24220332   PMID:24239175   PMID:24244022   PMID:24248895   PMID:24286194   PMID:24292944   PMID:24311639   PMID:24311785   PMID:24324549   PMID:24332808   PMID:24338844  
PMID:24344204   PMID:24362527   PMID:24386370   PMID:24388360   PMID:24403309   PMID:24427350   PMID:24434582   PMID:24440972   PMID:24448647   PMID:24455846   PMID:24474513   PMID:24478423  
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PMID:24823363   PMID:24829201   PMID:24833794   PMID:24842107   PMID:24850451   PMID:24887021   PMID:24931361   PMID:24939894   PMID:24958723   PMID:24965773   PMID:24979111   PMID:24982892  
PMID:25041835   PMID:25046655   PMID:25063885   PMID:25081983   PMID:25086068   PMID:25089569   PMID:25092917   PMID:25111005   PMID:25135296   PMID:25158264   PMID:25174715   PMID:25203434  
PMID:25212537   PMID:25237190   PMID:25240415   PMID:25256682   PMID:25263164   PMID:25280968   PMID:25289898   PMID:25313583   PMID:25336636   PMID:25344254   PMID:25356755   PMID:25367365  
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PMID:25824336   PMID:25825984   PMID:25830763   PMID:25839165   PMID:25854700   PMID:25857463   PMID:25894721   PMID:25911094   PMID:25921289   PMID:25955828   PMID:25958306   PMID:25995262  
PMID:26067657   PMID:26073085   PMID:26076738   PMID:26095157   PMID:26125867   PMID:26152212   PMID:26159734   PMID:26159767   PMID:26172215   PMID:26186194   PMID:26239765   PMID:26256210  
PMID:26283883   PMID:26318455   PMID:26334393   PMID:26344197   PMID:26350464   PMID:26370503   PMID:26377974   PMID:26386190   PMID:26408663   PMID:26414794   PMID:26418968   PMID:26420039  
PMID:26436690   PMID:26456826   PMID:26496610   PMID:26509557   PMID:26540630   PMID:26597572   PMID:26618866   PMID:26638075   PMID:26641717   PMID:26648324   PMID:26675717   PMID:26693891  
PMID:26719354   PMID:26749288   PMID:26763945   PMID:26777405   PMID:26860947   PMID:26895964   PMID:26898710   PMID:26900962   PMID:26903137   PMID:26930028   PMID:26935970   PMID:26952307  
PMID:26989177   PMID:26992288   PMID:26992741   PMID:27003228   PMID:27004522   PMID:27015362   PMID:27066976   PMID:27094578   PMID:27121503   PMID:27128974   PMID:27289231   PMID:27342126  
PMID:27353038   PMID:27375898   PMID:27377895   PMID:27390927   PMID:27460641   PMID:27460703   PMID:27462432   PMID:27478015   PMID:27499367   PMID:27509133   PMID:27519953   PMID:27524413  
PMID:27563827   PMID:27565712   PMID:27576135   PMID:27589736   PMID:27608849   PMID:27612856   PMID:27684187   PMID:27695111   PMID:27715399   PMID:27773610   PMID:27782833   PMID:27832972  
PMID:27834933   PMID:27840969   PMID:27841851   PMID:27876801   PMID:27880917   PMID:27929375   PMID:27966454   PMID:27974569   PMID:28003363   PMID:28049720   PMID:28075475   PMID:28096537  
PMID:28145580   PMID:28155694   PMID:28160423   PMID:28178656   PMID:28188308   PMID:28214208   PMID:28263956   PMID:28284838   PMID:28300015   PMID:28330616   PMID:28361350   PMID:28377405  
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PMID:28988530   PMID:29016609   PMID:29020611   PMID:29055076   PMID:29113685   PMID:29118431   PMID:29162887   PMID:29180619   PMID:29208031   PMID:29259017   PMID:29269512   PMID:29274868  
PMID:29295815   PMID:29301866   PMID:29332411   PMID:29361527   PMID:29371698   PMID:29393491   PMID:29395067   PMID:29402961   PMID:29476049   PMID:29507755   PMID:29511352   PMID:29567387  
PMID:29568061   PMID:29632027   PMID:29696533   PMID:29700202   PMID:29750423   PMID:29762071   PMID:29762819   PMID:29763414   PMID:29764950   PMID:29777904   PMID:30021884   PMID:30024968  
PMID:30065025   PMID:30088837   PMID:30089289   PMID:30097533   PMID:30194290   PMID:30194450   PMID:30201811   PMID:30243721   PMID:30258227   PMID:30280653   PMID:30293085   PMID:30369136  
PMID:30370584   PMID:30430889   PMID:30442766   PMID:30455686   PMID:30475060   PMID:30518533   PMID:30550785   PMID:30571736   PMID:30587575   PMID:30639242   PMID:30659093   PMID:30659120  
PMID:30664185   PMID:30670761   PMID:30688657   PMID:30711629   PMID:30719702   PMID:30784076   PMID:30833792   PMID:30918899   PMID:30949178   PMID:30992345   PMID:31043590   PMID:31056421  
PMID:31067453   PMID:31076511   PMID:31076515   PMID:31111299   PMID:31166991   PMID:31177093   PMID:31182282   PMID:31214872   PMID:31331973   PMID:31519588   PMID:31536960   PMID:31541017  
PMID:31586073   PMID:31639396   PMID:31641961   PMID:31654241   PMID:31661467   PMID:31676872   PMID:31678930   PMID:31696479   PMID:31732153   PMID:31779287   PMID:31806375   PMID:31858971  
PMID:31987794   PMID:31995728   PMID:32020235   PMID:32080801   PMID:32122157   PMID:32194036   PMID:32203165   PMID:32325713   PMID:32353859   PMID:32409323   PMID:32458278   PMID:32487760  
PMID:32518187   PMID:32541798   PMID:32567740   PMID:32630254   PMID:32694731   PMID:32745080   PMID:32788342   PMID:32814053   PMID:32859376   PMID:32877691   PMID:32882004   PMID:32896350  
PMID:32950474   PMID:33052069   PMID:33057850   PMID:33060197   PMID:33102950   PMID:33119040   PMID:33134373   PMID:33144569   PMID:33194618   PMID:33215388   PMID:33230889   PMID:33276802  
PMID:33341673   PMID:33360093   PMID:33404190   PMID:33477820   PMID:33477899   PMID:33578954   PMID:33629293   PMID:33671549   PMID:33843127   PMID:33957083   PMID:34079125   PMID:34182488  
PMID:34204767  


Genomics

Comparative Map Data
ITGB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1032,887,273 - 33,005,792 (-)EnsemblGRCh38hg38GRCh38
GRCh381032,900,318 - 32,958,230 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371033,189,246 - 33,247,158 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361033,229,326 - 33,287,204 (-)NCBINCBI36hg18NCBI36
Build 341033,236,244 - 33,264,492NCBI
Celera1032,954,580 - 33,012,639 (-)NCBI
Cytogenetic Map10p11.22NCBI
HuRef1032,908,756 - 32,966,834 (-)NCBIHuRef
CHM1_11033,190,855 - 33,248,907 (-)NCBICHM1_1
Itgb1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398129,412,135 - 129,460,060 (+)NCBIGRCm39mm39
GRCm39 Ensembl8129,412,135 - 129,459,681 (+)Ensembl
GRCm388128,685,654 - 128,733,579 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8128,685,654 - 128,733,200 (+)EnsemblGRCm38mm10GRCm38
MGSCv378131,209,554 - 131,257,479 (+)NCBIGRCm37mm9NCBIm37
MGSCv368131,571,871 - 131,619,287 (+)NCBImm8
Celera8133,002,434 - 133,050,263 (+)NCBICelera
Cytogenetic Map8E2NCBI
Itgb1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21956,705,123 - 56,753,199 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1956,705,171 - 56,753,195 (+)Ensembl
Rnor_6.01961,677,512 - 61,725,537 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1961,677,542 - 61,725,535 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01972,324,582 - 72,372,325 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41958,600,095 - 58,647,531 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11958,605,791 - 58,652,463 (-)NCBI
Celera1956,037,604 - 56,085,651 (+)NCBICelera
Cytogenetic Map19q12NCBI
Itgb1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554624,454,809 - 4,484,842 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554624,454,809 - 4,483,227 (+)NCBIChiLan1.0ChiLan1.0
ITGB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11033,608,978 - 33,662,258 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1033,608,978 - 33,644,031 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01033,023,573 - 33,081,384 (-)NCBIMhudiblu_PPA_v0panPan3
ITGB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.123,728,472 - 3,757,696 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl23,670,596 - 3,756,961 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha23,811,003 - 3,857,059 (+)NCBI
ROS_Cfam_1.024,006,817 - 4,053,107 (+)NCBI
UMICH_Zoey_3.123,785,306 - 3,831,383 (+)NCBI
UNSW_CanFamBas_1.023,819,236 - 3,865,356 (+)NCBI
UU_Cfam_GSD_1.023,939,078 - 3,985,170 (+)NCBI
Itgb1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934411,966,401 - 11,996,275 (-)NCBI
SpeTri2.0NW_0049365741,465,981 - 1,495,717 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ITGB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1056,078,398 - 56,173,795 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11056,078,393 - 56,130,608 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21061,450,695 - 61,502,941 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ITGB1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1932,201,030 - 32,258,247 (-)NCBI
ChlSab1.1 Ensembl932,202,204 - 32,258,154 (-)Ensembl
Vero_WHO_p1.0NW_02366605641,260,215 - 41,317,418 (-)NCBI
Itgb1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248058,748,848 - 8,800,259 (+)NCBI

Position Markers
RH47472  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371033,189,433 - 33,189,525UniSTSGRCh37
GRCh371914,733,900 - 14,733,992UniSTSGRCh37
Build 361033,229,439 - 33,229,531RGDNCBI36
Celera1914,627,056 - 14,627,148UniSTS
Celera1032,954,767 - 32,954,859RGD
Cytogenetic Map19pUniSTS
Cytogenetic Map19p13.1UniSTS
Cytogenetic Map10p11.2UniSTS
HuRef1032,908,943 - 32,909,035UniSTS
RH47140  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371033,189,699 - 33,189,889UniSTSGRCh37
GRCh371914,733,536 - 14,733,726UniSTSGRCh37
Build 361033,229,705 - 33,229,895RGDNCBI36
Celera1914,626,692 - 14,626,882UniSTS
Celera1032,955,033 - 32,955,223RGD
Cytogenetic Map19pUniSTS
Cytogenetic Map19p13.1UniSTS
Cytogenetic Map10p11.2UniSTS
HuRef1032,909,209 - 32,909,399UniSTS
RH40308  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371033,189,514 - 33,189,729UniSTSGRCh37
GRCh371914,733,696 - 14,733,911UniSTSGRCh37
Build 361033,229,520 - 33,229,735RGDNCBI36
Celera1914,626,852 - 14,627,067UniSTS
Celera1032,954,848 - 32,955,063RGD
Cytogenetic Map19pUniSTS
Cytogenetic Map19p13.1UniSTS
Cytogenetic Map10p11.2UniSTS
HuRef1032,909,024 - 32,909,239UniSTS
GDB:181546  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371033,189,413 - 33,189,995UniSTSGRCh37
GRCh371914,733,430 - 14,734,012UniSTSGRCh37
Build 361033,229,419 - 33,230,001RGDNCBI36
Celera1914,626,586 - 14,627,168UniSTS
Celera1032,954,747 - 32,955,329RGD
Cytogenetic Map19pUniSTS
Cytogenetic Map19p13.1UniSTS
Cytogenetic Map10p11.2UniSTS
HuRef1032,908,923 - 32,909,505UniSTS
SHGC-32719  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371033,189,811 - 33,189,939UniSTSGRCh37
GRCh371914,733,486 - 14,733,614UniSTSGRCh37
Build 361033,229,817 - 33,229,945RGDNCBI36
Celera1032,955,145 - 32,955,273RGD
Celera1914,626,642 - 14,626,770UniSTS
Cytogenetic Map19p13.1UniSTS
Cytogenetic Map10p11.2UniSTS
Cytogenetic Map19pUniSTS
HuRef1032,909,321 - 32,909,449UniSTS
TNG Radiation Hybrid Map1017460.0UniSTS
PMC59887P1  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371914,732,383 - 14,732,844UniSTSGRCh37
Build 361914,593,383 - 14,593,844RGDNCBI36
Celera1914,625,539 - 14,626,000RGD
Cytogenetic Map19pUniSTS
Cytogenetic Map19p13.1UniSTS
Cytogenetic Map10p11.2UniSTS
ITGB1_1823  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371033,189,316 - 33,189,924UniSTSGRCh37
Build 361033,229,322 - 33,229,930RGDNCBI36
Celera1032,954,650 - 32,955,258RGD
HuRef1032,908,826 - 32,909,434UniSTS
STS-M34189  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371033,196,377 - 33,196,525UniSTSGRCh37
Build 361033,236,383 - 33,236,531RGDNCBI36
Celera1032,961,713 - 32,961,861RGD
Cytogenetic Map10p11.2UniSTS
GeneMap99-GB4 RH Map10195.03UniSTS
NCBI RH Map10501.1UniSTS
D10S2370  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371033,190,227 - 33,190,488UniSTSGRCh37
Build 361033,230,233 - 33,230,494RGDNCBI36
Celera1032,955,561 - 32,955,822RGD
Cytogenetic Map19pUniSTS
Cytogenetic Map10p11.2UniSTS
HuRef1032,909,737 - 32,909,998UniSTS
Stanford-G3 RH Map101976.0UniSTS
GeneMap99-G3 RH Map101976.0UniSTS
D10S2354  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371033,196,862 - 33,196,968UniSTSGRCh37
Build 361033,236,868 - 33,236,974RGDNCBI36
Celera1032,962,198 - 32,962,304RGD
Cytogenetic Map19pUniSTS
Cytogenetic Map10p11.2UniSTS
HuRef1032,916,370 - 32,916,476UniSTS
G15908  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map10p11.2UniSTS

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
MIR124-2hsa-miR-124-3pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI21112327
MIR124-2hsa-miR-124-3pOncomiRDBexternal_infoNANA21112327
MIR183hsa-miR-183-5pMirtarbaseexternal_infoImmunoblot//Immunocytochemistry//Luciferase reportFunctional MTI19940135
MIR183hsa-miR-183-5pTarbaseexternal_infoReporter GenePOSITIVE
MIR183hsa-miR-183-5pOncomiRDBexternal_infoNANA19940135
MIR9-2hsa-miR-9-3pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI23530058

Predicted Target Of
Summary Value
Count of predictions:3053
Count of miRNA genes:710
Interacting mature miRNAs:807
Transcripts:ENST00000302278, ENST00000374956, ENST00000396033, ENST00000414670, ENST00000417122, ENST00000423113, ENST00000437302, ENST00000464001, ENST00000472147, ENST00000474568, ENST00000475184, ENST00000480226, ENST00000484088, ENST00000488427, ENST00000488494, ENST00000493758, ENST00000494395, ENST00000528877, ENST00000534049
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High 7 13 11 5 1 5 9 11 15 26 35 45 1
Medium 2425 2641 1694 601 1606 443 4346 2151 2849 385 1405 1563 170 1204 2788 4
Low 6 337 21 18 343 17 1 35 853 8 18 5 3 1 2 2
Below cutoff 1 12 2 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_029012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_002211 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_033668 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_133376 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AH003217 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI261443 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK291697 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL365203 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL710802 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC020057 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC113901 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM791591 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM973433 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX537407 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CX868374 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CX871886 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA600874 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DB063946 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DB292597 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M34189 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M84237 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U28252 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X68969 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000302278   ⟹   ENSP00000303351
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1032,900,318 - 32,958,230 (-)Ensembl
RefSeq Acc Id: ENST00000396033   ⟹   ENSP00000379350
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1032,900,319 - 32,957,894 (-)Ensembl
RefSeq Acc Id: ENST00000414670   ⟹   ENSP00000400544
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1032,932,521 - 32,958,196 (-)Ensembl
RefSeq Acc Id: ENST00000417122   ⟹   ENSP00000404546
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1032,900,333 - 32,958,275 (-)Ensembl
RefSeq Acc Id: ENST00000423113   ⟹   ENSP00000388694
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1032,900,319 - 32,935,558 (-)Ensembl
RefSeq Acc Id: ENST00000437302   ⟹   ENSP00000398029
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1032,900,333 - 32,957,865 (-)Ensembl
RefSeq Acc Id: ENST00000439974
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1032,958,486 - 32,960,503 (-)Ensembl
RefSeq Acc Id: ENST00000464001
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1032,929,932 - 32,932,717 (-)Ensembl
RefSeq Acc Id: ENST00000472147   ⟹   ENSP00000420416
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1032,929,985 - 32,936,251 (-)Ensembl
RefSeq Acc Id: ENST00000474568   ⟹   ENSP00000420282
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1032,906,010 - 32,958,199 (-)Ensembl
RefSeq Acc Id: ENST00000475184   ⟹   ENSP00000417243
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1032,922,778 - 33,005,792 (-)Ensembl
RefSeq Acc Id: ENST00000480226   ⟹   ENSP00000417537
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1032,928,150 - 32,955,663 (-)Ensembl
RefSeq Acc Id: ENST00000484088
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1032,925,961 - 32,958,218 (-)Ensembl
RefSeq Acc Id: ENST00000488427   ⟹   ENSP00000417508
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1032,900,333 - 32,958,227 (-)Ensembl
RefSeq Acc Id: ENST00000488494   ⟹   ENSP00000418725
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1032,900,333 - 32,958,227 (-)Ensembl
RefSeq Acc Id: ENST00000493758   ⟹   ENSP00000420792
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1032,929,934 - 32,935,558 (-)Ensembl
RefSeq Acc Id: ENST00000494395   ⟹   ENSP00000417799
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1032,901,564 - 32,912,064 (-)Ensembl
RefSeq Acc Id: ENST00000528877   ⟹   ENSP00000436214
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1032,929,885 - 32,963,283 (-)Ensembl
RefSeq Acc Id: ENST00000534049   ⟹   ENSP00000431326
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1032,928,212 - 32,992,463 (-)Ensembl
RefSeq Acc Id: ENST00000609742   ⟹   ENSP00000503306
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1032,887,273 - 32,958,253 (-)Ensembl
RefSeq Acc Id: ENST00000676460   ⟹   ENSP00000504641
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1032,906,319 - 32,958,253 (-)Ensembl
RefSeq Acc Id: ENST00000676623
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1032,900,333 - 32,958,253 (-)Ensembl
RefSeq Acc Id: ENST00000676659   ⟹   ENSP00000502979
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1032,900,414 - 32,958,272 (-)Ensembl
RefSeq Acc Id: ENST00000676895   ⟹   ENSP00000504454
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1032,900,333 - 32,958,253 (-)Ensembl
RefSeq Acc Id: ENST00000676964   ⟹   ENSP00000504267
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1032,900,333 - 32,958,232 (-)Ensembl
RefSeq Acc Id: ENST00000677310   ⟹   ENSP00000504508
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1032,900,426 - 32,958,280 (-)Ensembl
RefSeq Acc Id: ENST00000677363   ⟹   ENSP00000504791
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1032,900,277 - 32,958,199 (-)Ensembl
RefSeq Acc Id: ENST00000677999   ⟹   ENSP00000503546
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1032,900,333 - 32,958,251 (-)Ensembl
RefSeq Acc Id: ENST00000678120   ⟹   ENSP00000504784
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1032,900,333 - 32,958,253 (-)Ensembl
RefSeq Acc Id: ENST00000678479   ⟹   ENSP00000503110
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1032,900,333 - 32,958,247 (-)Ensembl
RefSeq Acc Id: ENST00000678591   ⟹   ENSP00000502883
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1032,900,333 - 32,958,220 (-)Ensembl
RefSeq Acc Id: ENST00000678701   ⟹   ENSP00000504205
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1032,900,333 - 32,957,466 (-)Ensembl
RefSeq Acc Id: ENST00000678766   ⟹   ENSP00000503538
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1032,900,412 - 32,958,253 (-)Ensembl
RefSeq Acc Id: ENST00000678943   ⟹   ENSP00000503916
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1032,900,333 - 32,958,220 (-)Ensembl
RefSeq Acc Id: ENST00000678952   ⟹   ENSP00000504444
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1032,900,333 - 32,958,251 (-)Ensembl
RefSeq Acc Id: ENST00000678989   ⟹   ENSP00000502882
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1032,887,332 - 32,958,325 (-)Ensembl
RefSeq Acc Id: ENST00000679187   ⟹   ENSP00000504012
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1032,900,333 - 32,958,247 (-)Ensembl
RefSeq Acc Id: NM_002211   ⟹   NP_002202
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381032,900,318 - 32,958,230 (-)NCBI
GRCh371033,189,246 - 33,247,293 (-)ENTREZGENE
Build 361033,229,326 - 33,287,204 (-)NCBI Archive
HuRef1032,908,756 - 32,966,834 (-)ENTREZGENE
CHM1_11033,190,855 - 33,248,907 (-)NCBI
Sequence:
RefSeq Acc Id: NM_033668   ⟹   NP_391988
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381032,900,318 - 32,935,558 (-)NCBI
GRCh371033,189,246 - 33,247,293 (-)ENTREZGENE
Build 361033,230,501 - 33,264,492 (-)NCBI Archive
HuRef1032,908,756 - 32,966,834 (-)ENTREZGENE
CHM1_11033,190,855 - 33,226,089 (-)NCBI
Sequence:
RefSeq Acc Id: NM_133376   ⟹   NP_596867
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381032,900,318 - 32,957,961 (-)NCBI
GRCh371033,189,246 - 33,247,293 (-)ENTREZGENE
Build 361033,230,504 - 33,286,828 (-)NCBI Archive
HuRef1032,908,756 - 32,966,834 (-)ENTREZGENE
CHM1_11033,190,855 - 33,248,436 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_002202 (Get FASTA)   NCBI Sequence Viewer  
  NP_391988 (Get FASTA)   NCBI Sequence Viewer  
  NP_596867 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA59182 (Get FASTA)   NCBI Sequence Viewer  
  AAA74402 (Get FASTA)   NCBI Sequence Viewer  
  AAA74403 (Get FASTA)   NCBI Sequence Viewer  
  AAA79832 (Get FASTA)   NCBI Sequence Viewer  
  AAA79833 (Get FASTA)   NCBI Sequence Viewer  
  AAA79834 (Get FASTA)   NCBI Sequence Viewer  
  AAA79835 (Get FASTA)   NCBI Sequence Viewer  
  AAA81366 (Get FASTA)   NCBI Sequence Viewer  
  AAH20057 (Get FASTA)   NCBI Sequence Viewer  
  AAI13902 (Get FASTA)   NCBI Sequence Viewer  
  BAF84386 (Get FASTA)   NCBI Sequence Viewer  
  CAD97649 (Get FASTA)   NCBI Sequence Viewer  
  EAW85948 (Get FASTA)   NCBI Sequence Viewer  
  EAW85949 (Get FASTA)   NCBI Sequence Viewer  
  EAW85950 (Get FASTA)   NCBI Sequence Viewer  
  EAW85951 (Get FASTA)   NCBI Sequence Viewer  
  EAW85952 (Get FASTA)   NCBI Sequence Viewer  
  EAW85953 (Get FASTA)   NCBI Sequence Viewer  
  EAW85954 (Get FASTA)   NCBI Sequence Viewer  
  EAW85955 (Get FASTA)   NCBI Sequence Viewer  
  EAW85956 (Get FASTA)   NCBI Sequence Viewer  
  EAW85957 (Get FASTA)   NCBI Sequence Viewer  
  EAW85958 (Get FASTA)   NCBI Sequence Viewer  
  EAW85959 (Get FASTA)   NCBI Sequence Viewer  
  EAW85960 (Get FASTA)   NCBI Sequence Viewer  
  P05556 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_002202   ⟸   NM_002211
- Peptide Label: isoform 1A precursor
- UniProtKB: P05556 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_596867   ⟸   NM_133376
- Peptide Label: isoform 1A precursor
- UniProtKB: P05556 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_391988   ⟸   NM_033668
- Peptide Label: isoform 1D precursor
- UniProtKB: P05556 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSP00000388694   ⟸   ENST00000423113
RefSeq Acc Id: ENSP00000400544   ⟸   ENST00000414670
RefSeq Acc Id: ENSP00000420792   ⟸   ENST00000493758
RefSeq Acc Id: ENSP00000417799   ⟸   ENST00000494395
RefSeq Acc Id: ENSP00000417537   ⟸   ENST00000480226
RefSeq Acc Id: ENSP00000431326   ⟸   ENST00000534049
RefSeq Acc Id: ENSP00000404546   ⟸   ENST00000417122
RefSeq Acc Id: ENSP00000420416   ⟸   ENST00000472147
RefSeq Acc Id: ENSP00000303351   ⟸   ENST00000302278
RefSeq Acc Id: ENSP00000417508   ⟸   ENST00000488427
RefSeq Acc Id: ENSP00000418725   ⟸   ENST00000488494
RefSeq Acc Id: ENSP00000420282   ⟸   ENST00000474568
RefSeq Acc Id: ENSP00000379350   ⟸   ENST00000396033
RefSeq Acc Id: ENSP00000436214   ⟸   ENST00000528877
RefSeq Acc Id: ENSP00000417243   ⟸   ENST00000475184
RefSeq Acc Id: ENSP00000398029   ⟸   ENST00000437302
RefSeq Acc Id: ENSP00000503306   ⟸   ENST00000609742
RefSeq Acc Id: ENSP00000504267   ⟸   ENST00000676964
RefSeq Acc Id: ENSP00000504454   ⟸   ENST00000676895
RefSeq Acc Id: ENSP00000502979   ⟸   ENST00000676659
RefSeq Acc Id: ENSP00000504641   ⟸   ENST00000676460
RefSeq Acc Id: ENSP00000504791   ⟸   ENST00000677363
RefSeq Acc Id: ENSP00000504508   ⟸   ENST00000677310
RefSeq Acc Id: ENSP00000503546   ⟸   ENST00000677999
RefSeq Acc Id: ENSP00000503110   ⟸   ENST00000678479
RefSeq Acc Id: ENSP00000504784   ⟸   ENST00000678120
RefSeq Acc Id: ENSP00000504205   ⟸   ENST00000678701
RefSeq Acc Id: ENSP00000503538   ⟸   ENST00000678766
RefSeq Acc Id: ENSP00000502883   ⟸   ENST00000678591
RefSeq Acc Id: ENSP00000503916   ⟸   ENST00000678943
RefSeq Acc Id: ENSP00000504444   ⟸   ENST00000678952
RefSeq Acc Id: ENSP00000502882   ⟸   ENST00000678989
RefSeq Acc Id: ENSP00000504012   ⟸   ENST00000679187
Protein Domains
EGF_2   INB   Integrin_b_cyt   PSI   PSI_integrin   VWFA

Promoters
RGD ID:7217325
Promoter ID:EPDNEW_H14408
Type:initiation region
Name:ITGB1_1
Description:integrin subunit beta 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381032,958,220 - 32,958,280EPDNEW
RGD ID:6787789
Promoter ID:HG_KWN:9099
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:HeLa_S3
Transcripts:OTTHUMT00000047498
Position:
Human AssemblyChrPosition (strand)Source
Build 361033,282,661 - 33,283,162 (-)MPROMDB
RGD ID:6809827
Promoter ID:HG_ACW:7664
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:K562
Transcripts:ITGB1.HAPR07
Position:
Human AssemblyChrPosition (strand)Source
Build 361033,284,156 - 33,284,656 (-)MPROMDB
RGD ID:6787817
Promoter ID:HG_KWN:9100
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000302252,   ENST00000359614,   ENST00000374956,   NM_002211,   NM_133376,   OTTHUMT00000047497,   OTTHUMT00000047501,   OTTHUMT00000047507,   OTTHUMT00000047511
Position:
Human AssemblyChrPosition (strand)Source
Build 361033,285,861 - 33,288,207 (-)MPROMDB

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 10p11.22-11.1(chr10:31999920-38119681)x3 copy number gain See cases [RCV000135414] Chr10:31999920..38119681 [GRCh38]
Chr10:32288848..38408609 [GRCh37]
Chr10:32328854..38448615 [NCBI36]
Chr10:10p11.22-11.1
pathogenic
GRCh38/hg38 10p15.1-q11.22(chr10:4604734-48074662)x3 copy number gain See cases [RCV000141497] Chr10:4604734..48074662 [GRCh38]
Chr10:4646926..47531169 [GRCh37]
Chr10:4636926..47125152 [NCBI36]
Chr10:10p15.1-q11.22
benign
GRCh37/hg19 10p11.22-11.21(chr10:32323692-37520394)x3 copy number gain Ductal breast carcinoma [RCV000207153] Chr10:32323692..37520394 [GRCh37]
Chr10:10p11.22-11.21
uncertain significance
GRCh37/hg19 10p11.22(chr10:33086451-33279862) copy number gain Abnormality of esophagus morphology [RCV000416878] Chr10:33086451..33279862 [GRCh37]
Chr10:10p11.22
likely benign
GRCh37/hg19 10p15.3-q26.3(chr10:93297-135378918)x3 copy number gain See cases [RCV000448750] Chr10:93297..135378918 [GRCh37]
Chr10:10p15.3-q26.3
pathogenic
GRCh37/hg19 10p15.3-q26.3(chr10:100027-135427143) copy number gain See cases [RCV000511389] Chr10:100027..135427143 [GRCh37]
Chr10:10p15.3-q26.3
pathogenic|uncertain significance
GRCh37/hg19 10p15.3-q11.23(chr10:100026-50961640)x3 copy number gain See cases [RCV000510893] Chr10:100026..50961640 [GRCh37]
Chr10:10p15.3-q11.23
pathogenic
GRCh37/hg19 10p15.3-q26.3(chr10:100027-135427143)x3 copy number gain See cases [RCV000510861] Chr10:100027..135427143 [GRCh37]
Chr10:10p15.3-q26.3
pathogenic
NM_002211.4(ITGB1):c.2303dup (p.Glu769fs) duplication Neural tube defect [RCV000709687] Chr10:32908395..32908396 [GRCh38]
Chr10:33197323..33197324 [GRCh37]
Chr10:10p11.22
risk factor
GRCh37/hg19 10p15.3-q26.3(chr10:73232-135524321)x3 copy number gain not provided [RCV000749464] Chr10:73232..135524321 [GRCh37]
Chr10:10p15.3-q26.3
pathogenic
GRCh37/hg19 10p15.3-q26.3(chr10:98087-135477883)x3 copy number gain not provided [RCV000749465] Chr10:98087..135477883 [GRCh37]
Chr10:10p15.3-q26.3
pathogenic
NM_002211.4(ITGB1):c.639C>T (p.Cys213=) single nucleotide variant not provided [RCV000940525] Chr10:32926018 [GRCh38]
Chr10:33214946 [GRCh37]
Chr10:10p11.22
likely benign
NM_002211.4(ITGB1):c.2164+10C>T single nucleotide variant not provided [RCV000944812] Chr10:32910213 [GRCh38]
Chr10:33199141 [GRCh37]
Chr10:10p11.22
likely benign
NM_002211.4(ITGB1):c.1809C>T (p.Asn603=) single nucleotide variant not provided [RCV000883894] Chr10:32911570 [GRCh38]
Chr10:33200498 [GRCh37]
Chr10:10p11.22
benign
NM_002211.4(ITGB1):c.2252G>A (p.Trp751Ter) single nucleotide variant Esophageal atresia [RCV000984658] Chr10:32908447 [GRCh38]
Chr10:33197375 [GRCh37]
Chr10:10p11.22
uncertain significance
NM_002211.4(ITGB1):c.505C>T (p.Leu169=) single nucleotide variant not provided [RCV000881149] Chr10:32928136 [GRCh38]
Chr10:33217064 [GRCh37]
Chr10:10p11.22
benign
GRCh37/hg19 10p11.22(chr10:33083542-33298983)x3 copy number gain not provided [RCV000847155] Chr10:33083542..33298983 [GRCh37]
Chr10:10p11.22
uncertain significance
GRCh37/hg19 10p11.22(chr10:33220122-33300851)x3 copy number gain not provided [RCV000846650] Chr10:33220122..33300851 [GRCh37]
Chr10:10p11.22
uncertain significance
NM_002211.4(ITGB1):c.942+8C>T single nucleotide variant not provided [RCV000952946] Chr10:32923577 [GRCh38]
Chr10:33212505 [GRCh37]
Chr10:10p11.22
benign
NM_002211.4(ITGB1):c.67+5A>G single nucleotide variant not provided [RCV000956817] Chr10:32935487 [GRCh38]
Chr10:33224415 [GRCh37]
Chr10:10p11.22
benign

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:6153 AgrOrtholog
COSMIC ITGB1 COSMIC
Ensembl Genes ENSG00000150093 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000303351 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000379350 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000388694 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000398029 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSP00000400544 UniProtKB/TrEMBL
  ENSP00000404546 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSP00000417508 UniProtKB/TrEMBL
  ENSP00000417537 UniProtKB/TrEMBL
  ENSP00000417799 UniProtKB/TrEMBL
  ENSP00000418725 UniProtKB/TrEMBL
  ENSP00000420282 UniProtKB/TrEMBL
  ENSP00000420416 UniProtKB/TrEMBL
  ENSP00000431326 UniProtKB/TrEMBL
  ENSP00000436214 UniProtKB/TrEMBL
  ENSP00000502882 UniProtKB/Swiss-Prot
  ENSP00000502883 UniProtKB/TrEMBL
  ENSP00000502979 UniProtKB/Swiss-Prot
  ENSP00000503110 UniProtKB/TrEMBL
  ENSP00000503306 UniProtKB/TrEMBL
  ENSP00000503538 UniProtKB/Swiss-Prot
  ENSP00000503546 UniProtKB/Swiss-Prot
  ENSP00000503916 UniProtKB/Swiss-Prot
  ENSP00000504012 UniProtKB/TrEMBL
  ENSP00000504205 UniProtKB/Swiss-Prot
  ENSP00000504267 UniProtKB/TrEMBL
  ENSP00000504444 UniProtKB/Swiss-Prot
  ENSP00000504454 UniProtKB/TrEMBL
  ENSP00000504508 UniProtKB/Swiss-Prot
  ENSP00000504641 UniProtKB/Swiss-Prot
  ENSP00000504784 UniProtKB/TrEMBL
  ENSP00000504791 UniProtKB/TrEMBL
Ensembl Transcript ENST00000302278 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000396033 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000414670 UniProtKB/TrEMBL
  ENST00000417122 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENST00000423113 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000437302 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENST00000472147 UniProtKB/TrEMBL
  ENST00000474568 UniProtKB/TrEMBL
  ENST00000480226 UniProtKB/TrEMBL
  ENST00000488427 UniProtKB/TrEMBL
  ENST00000488494 UniProtKB/TrEMBL
  ENST00000494395 UniProtKB/TrEMBL
  ENST00000528877 UniProtKB/TrEMBL
  ENST00000534049 UniProtKB/TrEMBL
  ENST00000609742 UniProtKB/TrEMBL
  ENST00000676460 UniProtKB/Swiss-Prot
  ENST00000676659 UniProtKB/Swiss-Prot
  ENST00000676895 UniProtKB/TrEMBL
  ENST00000676964 UniProtKB/TrEMBL
  ENST00000677310 UniProtKB/Swiss-Prot
  ENST00000677363 UniProtKB/TrEMBL
  ENST00000677999 UniProtKB/Swiss-Prot
  ENST00000678120 UniProtKB/TrEMBL
  ENST00000678479 UniProtKB/TrEMBL
  ENST00000678591 UniProtKB/TrEMBL
  ENST00000678701 UniProtKB/Swiss-Prot
  ENST00000678766 UniProtKB/Swiss-Prot
  ENST00000678943 UniProtKB/Swiss-Prot
  ENST00000678952 UniProtKB/Swiss-Prot
  ENST00000678989 UniProtKB/Swiss-Prot
  ENST00000679187 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.410 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000150093 GTEx
HGNC ID HGNC:6153 ENTREZGENE
Human Proteome Map ITGB1 Human Proteome Map
InterPro EGF_extracell UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  I-EGF_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Integrin_beta-1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Integrin_beta_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Integrin_bsu UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Integrin_bsu_cyt_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Integrin_bsu_tail UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Integrin_bsu_tail_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Integrin_bsu_VWA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Integrin_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PSI UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  vWFA_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:3688 UniProtKB/Swiss-Prot
NCBI Gene 3688 ENTREZGENE
OMIM 135630 OMIM
PANTHER PTHR10082 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10082:SF28 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam EGF_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  I-EGF_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Integrin_b_cyt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Integrin_B_tail UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Integrin_beta UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PSI_integrin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA29953 PharmGKB
PIRSF Integrin_B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS INTEGRINB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE EGF_1 UniProtKB/Swiss-Prot
  INTEGRIN_BETA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART INB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Integrin_b_cyt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Integrin_B_tail UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PSI UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF53300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF69179 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF69687 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A7I2V2F9_HUMAN UniProtKB/TrEMBL
  A0A7I2V2T4_HUMAN UniProtKB/TrEMBL
  A0A7I2V348_HUMAN UniProtKB/TrEMBL
  A0A7I2V5T3_HUMAN UniProtKB/TrEMBL
  A0A7I2V5Z8_HUMAN UniProtKB/TrEMBL
  C9JNE0_HUMAN UniProtKB/TrEMBL
  C9JPK5_HUMAN UniProtKB/TrEMBL
  E7EQW5_HUMAN UniProtKB/TrEMBL
  E7EUI6_HUMAN UniProtKB/TrEMBL
  E9PLR6_HUMAN UniProtKB/TrEMBL
  E9PQJ2_HUMAN UniProtKB/TrEMBL
  H7C4K3_HUMAN UniProtKB/TrEMBL
  H7C4N8_HUMAN UniProtKB/TrEMBL
  ITB1_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
  Q5T3E4_HUMAN UniProtKB/TrEMBL
  Q5T3E5_HUMAN UniProtKB/TrEMBL
  Q5T3E6_HUMAN UniProtKB/TrEMBL
UniProt Secondary A8K6N2 UniProtKB/Swiss-Prot
  D3DRX9 UniProtKB/Swiss-Prot
  D3DRY3 UniProtKB/Swiss-Prot
  D3DRY4 UniProtKB/Swiss-Prot
  D3DRY5 UniProtKB/Swiss-Prot
  P78466 UniProtKB/Swiss-Prot
  P78467 UniProtKB/Swiss-Prot
  Q13089 UniProtKB/Swiss-Prot
  Q13090 UniProtKB/Swiss-Prot
  Q13091 UniProtKB/Swiss-Prot
  Q13212 UniProtKB/Swiss-Prot
  Q14622 UniProtKB/Swiss-Prot
  Q14647 UniProtKB/Swiss-Prot
  Q29RW2 UniProtKB/Swiss-Prot
  Q7Z3V1 UniProtKB/Swiss-Prot
  Q8WUM6 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-22 ITGB1  integrin subunit beta 1  ITGB1  integrin beta 1  Symbol and/or name change 5135510 APPROVED
2015-11-17 ITGB1  integrin beta 1  ITGB1  integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)  Symbol and/or name change 5135510 APPROVED