GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Itgb1 | affects response to substance | ISO | ITGB1 (Homo sapiens) | 6480464 | CTD | ITGB1 protein affects the susceptibility to Cisplatin | PMID:21720550 | Itgb1 | increases expression | ISO | ITGB1 (Homo sapiens) | 6480464 | CTD | Cisplatin results in increased expression of ITGB1 mRNA | PMID:25596134 PMID:27594783 | Itgb1 | multiple interactions | ISO | ITGB1 (Homo sapiens) | 6480464 | CTD | [ITGB1 protein results in increased activity of EGFR protein] which results in decreased susceptibility to Cisplatin | PMID:21478906 | |
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