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Gene: Nr4a3 (nuclear receptor subfamily 4, group A, member 3) Rattus norvegicus
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Symbol: Nr4a3
Name: nuclear receptor subfamily 4, group A, member 3
Description: Exhibits several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; glucocorticoid receptor binding activity; and protein homodimerization activity. Involved in several processes, including animal organ regeneration; positive regulation of cardiac muscle hypertrophy; and regulation of type B pancreatic cell proliferation. Predicted to localize to nucleus and transcription factor complex. Human ortholog(s) of this gene implicated in extraskeletal myxoid chondrosarcoma. Orthologous to human NR4A3 (nuclear receptor subfamily 4 group A member 3); INTERACTS WITH 1,2,4-trimethylbenzene; 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: neuron-derived orphan receptor; neuron-derived orphan receptor 1; neuron-derived orphan receptor 1/2; NOR-2; nuclear hormone receptor NOR-1/NOR-2; nuclear receptor subfamily 4 group A member 3
Orthologs:
Homo sapiens (human) : NR4A3 (nuclear receptor subfamily 4 group A member 3)  HGNC  Alliance
Mus musculus (house mouse) : Nr4a3 (nuclear receptor subfamily 4, group A, member 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nr4a3 (nuclear receptor subfamily 4 group A member 3)
Pan paniscus (bonobo/pygmy chimpanzee) : NR4A3 (nuclear receptor subfamily 4 group A member 3)
Canis lupus familiaris (dog) : NR4A3 (nuclear receptor subfamily 4 group A member 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nr4a3 (nuclear receptor subfamily 4 group A member 3)
Sus scrofa (pig) : NR4A3 (nuclear receptor subfamily 4 group A member 3)
Chlorocebus sabaeus (African green monkey) : NR4A3 (nuclear receptor subfamily 4 group A member 3)
Heterocephalus glaber (naked mole-rat) : Nr4a3 (nuclear receptor subfamily 4 group A member 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0563,781,801 - 63,822,890 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl563,781,801 - 63,821,637 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0568,298,772 - 68,339,861 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4564,713,468 - 64,753,311 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1564,718,506 - 64,758,343 (+)NCBI
Celera565,193,786 - 65,233,628 (-)NCBICelera
Cytogenetic Map5q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Nr4a3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 61882
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2020-05-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.