Bw134 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Bw134 (Body weight QTL 134) Rattus norvegicus

Symbol: Bw134
Name: Body weight QTL 134
RGD ID: 7411561
Trait: body mass   (VT:0001259)    
Measurement Type: body weight gain   (CMO:0000420)    
LOD Score: 24.0
P Value: 0.001
Variance: 22.8
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2549,463,600 - 94,463,600RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0551,804,426 - 96,804,426RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0555,954,492 - 100,954,492RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4552,659,478 - 97,659,478RGD_MAPPER_PIPELINERGSC3.4
Cross Type: intercross
Strains Crossed: F344/IcoCrlf LOU/NimrOlaHsd 




  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bw134RatBody Weight  IAGP 7401255 RGD 

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bw134Ratincreased body weight  IDA 7401255 RGD 

Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bw134Ratbody weight gain  IDA 7401255 RGD 

Experimental Condition
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bw134Ratcontrol condition  IDA 7401255 RGD 

Measurement Method
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bw134Ratbody weighing method  IDA 7401255 RGD 

Rat Strain
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bw134RatF344/IcoCrlf  IEA 7401255 RGD 
Bw134RatLOU/NimrOlaHsd  IEA 7401255 RGD 

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bw134Ratbody mass  IDA 7401255 RGD 


#
Reference Title
Reference Citation
1. QTLs influencing carbohydrate and fat choice in a LOU/CxFischer 344 F2 rat population. Marissal-Arvy N, etal., Obesity (Silver Spring). 2013 Apr 17. doi: 10.1002/oby.20485.


1 to 20 of 501 rows
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
61931Zfp292zinc finger protein 29254938417749468177Rat
11452394LOC108350953small ubiquitin-related modifier 2 pseudogene54948279049483777Rat
620436Cgaglycoprotein hormones, alpha polypeptide54948691549499192Rat
1586081Rpl23a-ps17ribosomal protein L23a, pseudogene 1754950771649508319Rat
41270715Ubr7-ps1ubiquitin protein ligase E3 component n-recognin 7, pseudogene 154951026449512757Rat
1560696Mob3bMOB kinase activator 3B54954625449737934Rat
7657583LOC102549876uncharacterized LOC10254987654958355049587920Rat
1584099Luc7l3-ps2LUC7-like 3 pre-mRNA splicing factor, pseudogene 254965348749655419Rat
1309045Ifnkinterferon kappa54973207349734281Rat
7641478Rpl10a-ps2ribosomal protein L10A, pseudogene 254973891149739989Rat
41194781LOC120103371U4 spliceosomal RNA54974815649748295Rat
1359108RGD1359108similar to RIKEN cDNA 3110043O2154976634049791434Rat
1310773Lingo2leucine rich repeat and Ig domain containing 255037074451687252Rat
41316018U6l1U6 spliceosomal RNA like 155046074850460853Rat
2325412Mir876microRNA 87655133719151337269Rat
2325356Mir873microRNA 87355135691951356995Rat
1592194Hnrnpk-ps6heterogeneous nuclear ribonucleoprotein K, pseudogene 655181298851817585Rat
2322670Rbsn5l-ps1rabenosyn-5 like, pseudogene 155279522552797778Rat
41389895Tuba1a-ps5tubulin, alpha 1A, pseudogene 555290789152911653Rat
1586080Ldha-ps4lactate dehydrogenase A, pseudogene 455313501053136103Rat

1 to 20 of 501 rows
1 to 20 of 643 rows
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Expected Size
Chr
Start
Stop
Species
Match
10931D5Wox1322657516579275166041Ratregion
33836D5Mit912156029343460293557Ratregion
33921D5Mit219456928513369285327Ratregion
33967D5Mit329658108229081082586Ratregion
33981D5Mit426659045014490450412Ratregion
33985D5Mit1113358361072983610862Ratregion
34047D5Mit113655596227855962414Ratregion
34057D5Mit1713557196353371963668Ratregion
34144D5Mgh1114457425132074251464Ratregion
34170D5Mgh2412657830912778309253Ratregion
34216D5Mgh614056898430768984447Ratregion
34322D5Mgh1012955979339959793528Ratregion
34501D5Mgh2614255580560655805750Ratregion
33678D5Mit108655571562255715708Ratregion
36135D5Rat2017458463946784639641Ratregion
36177D5Rat913555882923658829371Ratregion
37440D5Rat8415256954029569540447Ratregion
36946D5Rat716155571562655715787Ratregion
37684D5Rat7620056558701265587212Ratregion
37992D5Rat10224055686914956869389Ratregion
1 to 20 of 643 rows

Peak: (D5Mit17)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2571,963,533 - 71,963,668 (+)MAPPER
Rnor_6.0574,304,359 - 74,304,493NCBI
Rnor_5.0578,454,425 - 78,454,559UniSTS
RGSC_v3.4575,159,412 - 75,159,546UniSTS
RGSC_v3.4575,159,411 - 75,159,546RGD
RGSC_v3.1575,164,525 - 75,164,659RGD
Celera570,813,108 - 70,813,242UniSTS
RH 3.4 Map5487.8UniSTS
RH 3.4 Map5487.8RGD
RH 2.0 Map5371.2RGD
Cytogenetic Map5q24UniSTS


1 to 10 of 68 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2293666Bmd38Bone mineral density QTL 384.4femur size trait (VT:1000369)femoral neck cortical cross-sectional area (CMO:0001702)5894822853948228Rat
1578776Stresp18Stress response QTL 182.9thymus mass (VT:0004954)thymus wet weight (CMO:0000855)52795544072955440Rat
1298067Scl15Serum cholesterol level QTL 154.80.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53321566578215665Rat
1300115Hrtrt7Heart rate QTL 72.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)54786906290099692Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
6907115Mcs29Mammary carcinoma susceptibility QTL 29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)57781615577988860Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)51887394774251464Rat
1298070Scl18Serum cholesterol level QTL 183.7blood LDL cholesterol amount (VT:0000181)calculated plasma low density lipoprotein cholesterol level (CMO:0001245)579584860124584860Rat
1598868Mcs12Mammary carcinoma susceptibility QTL 120.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)55897344960051321Rat
2302381Bw84Body weight QTL 844.47body mass (VT:0001259)body mass index (BMI) (CMO:0000105)568984307104251008Rat

1 to 10 of 68 rows


Note Type Note Reference
qtl_cross_type intercross 7401255
qtl_general weight gain is correlated to the total calorie intake 7401255
qtl_general software package used: multiple interval mapping (MIM); MultiQTL software (version 2.6); ANOVA 7401255
qtl_general measurement method: At 16 weeks of age animals were individually housed and given self-selection diet (protein, carbohydrate and fat diet in three separate cups); rats were weighed 3 times per week for 3 weeks 7401255
qtl_general number of animals used: 94 F2 females 7401255
qtl_map spans from 67.2-74.2 Mb; peak at 70.7 Mb 7401255