(-)-alpha-phellandrene decreases expression ISO RGD:68519 6480464 alpha phellandrene results in decreased expression of SIGMAR1 mRNA CTD PMID:25075043 (1->4)-beta-D-glucan multiple interactions ISO RGD:68520 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of SIGMAR1 mRNA CTD PMID:36331819 1,2-dichloroethane increases expression ISO RGD:68520 6480464 ethylene dichloride results in increased expression of SIGMAR1 mRNA CTD PMID:28960355 1,2-dimethylhydrazine increases expression ISO RGD:68520 6480464 1, 2-Dimethylhydrazine results in increased expression of SIGMAR1 mRNA CTD PMID:22206623 1-[2-(3,4-dichlorophenyl)ethyl]-4-methylpiperazine decreases activity ISO RGD:68519 6480464 1-(2-(3, 4-dichlorophenyl)ethyl)-4-methylpiperazine results in decreased activity of SIGMAR1 protein CTD PMID:30661753 1-[2-(3,4-dichlorophenyl)ethyl]-4-methylpiperazine decreases activity ISO RGD:68520 6480464 1-(2-(3, 4-dichlorophenyl)ethyl)-4-methylpiperazine results in decreased activity of SIGMAR1 protein CTD PMID:30661753 14-Deoxy-11,12-didehydroandrographolide decreases expression ISO RGD:68519 6480464 14-deoxy-11, 12-didehydroandrographolide results in decreased expression of SIGMAR1 mRNA CTD PMID:22101062 17alpha-ethynylestradiol affects expression ISO RGD:68520 6480464 Ethinyl Estradiol affects the expression of SIGMAR1 mRNA CTD PMID:17555576 17alpha-ethynylestradiol multiple interactions ISO RGD:68520 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SIGMAR1 mRNA CTD PMID:17942748 17alpha-ethynylestradiol increases expression ISO RGD:68520 6480464 Ethinyl Estradiol results in increased expression of SIGMAR1 mRNA CTD PMID:17942748 17beta-estradiol affects expression EXP 6480464 Estradiol affects the expression of SIGMAR1 mRNA CTD PMID:32145629 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO RGD:68520 6480464 [Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:28433925 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:68520 6480464 [Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:17942748 more ... 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of SIGMAR1 mRNA CTD PMID:34747641 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:68520 6480464 Tetrachlorodibenzodioxin results in decreased expression of SIGMAR1 mRNA CTD PMID:28213091 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:68520 6480464 Tetrachlorodibenzodioxin affects the expression of SIGMAR1 mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of SIGMAR1 mRNA CTD PMID:22298810 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:68520 6480464 Tetrachlorodibenzodioxin results in increased expression of SIGMAR1 mRNA CTD PMID:17942748 3,3',4,4',5-pentachlorobiphenyl increases expression EXP 6480464 3 more ... CTD PMID:23196670 3,3',5-triiodo-L-thyronine increases expression EXP 6480464 Triiodothyronine results in increased expression of SIGMAR1 mRNA CTD PMID:15953391 3H-1,2-dithiole-3-thione increases expression EXP 6480464 1, 2-dithiol-3-thione results in increased expression of SIGMAR1 mRNA CTD PMID:19162173 4-hydroxyphenyl retinamide decreases expression ISO RGD:68520 6480464 Fenretinide results in decreased expression of SIGMAR1 mRNA CTD PMID:28973697 acetylcholine multiple interactions EXP 6480464 [1-(3-(4-(3-chlorophenyl)-1-piperazinyl)propyl)-3 more ... CTD PMID:11907181 acrylamide decreases expression ISO RGD:68519 6480464 Acrylamide results in decreased expression of SIGMAR1 mRNA CTD PMID:32763439 aflatoxin B1 decreases expression ISO RGD:68520 6480464 Aflatoxin B1 results in decreased expression of SIGMAR1 mRNA CTD PMID:19770486 all-trans-retinoic acid decreases expression ISO RGD:68519 6480464 Tretinoin results in decreased expression of SIGMAR1 mRNA CTD PMID:33167477 alpha-phellandrene decreases expression ISO RGD:68519 6480464 alpha phellandrene results in decreased expression of SIGMAR1 mRNA CTD PMID:25075043 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of SIGMAR1 mRNA CTD PMID:16483693 Aroclor 1254 decreases expression ISO RGD:68520 6480464 Chlorodiphenyl (54% Chlorine) results in decreased expression of SIGMAR1 mRNA CTD PMID:25270620 arsenite(3-) multiple interactions ISO RGD:68519 6480464 arsenite promotes the reaction [G3BP1 protein binds to SIGMAR1 mRNA] CTD PMID:32406909 Bardoxolone methyl multiple interactions ISO RGD:68519 6480464 ursolic acid inhibits the reaction [bardoxolone methyl results in decreased expression of SIGMAR1 protein] CTD PMID:36587836 Bardoxolone methyl decreases expression ISO RGD:68519 6480464 bardoxolone methyl results in decreased expression of SIGMAR1 protein CTD PMID:36587836 benzo[a]pyrene decreases expression ISO RGD:68519 6480464 Benzo(a)pyrene results in decreased expression of SIGMAR1 mRNA CTD PMID:20106945 bis(2-ethylhexyl) phthalate multiple interactions ISO RGD:68520 6480464 [Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:28433925 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of SIGMAR1 mRNA CTD PMID:25181051 , PMID:32145629 bisphenol A multiple interactions ISO RGD:68520 6480464 [Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:28433925 bortezomib decreases expression ISO RGD:68519 6480464 Bortezomib results in decreased expression of SIGMAR1 mRNA CTD PMID:20977926 cadmium atom multiple interactions ISO RGD:68519 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SIGMAR1 mRNA CTD PMID:35301059 cadmium dichloride multiple interactions ISO RGD:68519 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SIGMAR1 mRNA CTD PMID:35301059 caffeine decreases expression EXP 6480464 Caffeine results in decreased expression of SIGMAR1 mRNA CTD PMID:20864626 carbon nanotube decreases expression ISO RGD:68520 6480464 Nanotubes more ... CTD PMID:25620056 carbon nanotube increases expression ISO RGD:68520 6480464 Nanotubes, Carbon results in increased expression of SIGMAR1 mRNA CTD PMID:25554681 cisplatin multiple interactions ISO RGD:68519 6480464 [Cisplatin co-treated with jinfukang] results in increased expression of SIGMAR1 mRNA CTD PMID:27392435 clofibrate multiple interactions ISO RGD:68520 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of SIGMAR1 mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of SIGMAR1 mRNA] CTD PMID:17585979 clofibric acid affects expression EXP 6480464 Clofibric Acid affects the expression of SIGMAR1 mRNA CTD PMID:17602206 clofibric acid multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of SIGMAR1 mRNA CTD PMID:17602206 cobalt dichloride decreases expression ISO RGD:68519 6480464 cobaltous chloride results in decreased expression of SIGMAR1 mRNA CTD PMID:19320972 , PMID:19376846 cocaine multiple interactions ISO RGD:68519 6480464 1-propyl-5-(3-p-tolylisoxazol-5-yl)-1 more ... CTD PMID:20956312 cocaine increases response to substance ISO RGD:68520 6480464 SIGMAR1 mRNA results in increased susceptibility to Cocaine CTD PMID:11426838 cocaine decreases response to substance ISO RGD:68520 6480464 SIGMAR1 gene mutant form results in decreased susceptibility to Cocaine CTD PMID:11006959 cocaine multiple interactions ISO RGD:68520 6480464 Cocaine results in increased activity of and results in increased localization of SIGMAR1 protein more ... CTD PMID:20354174 cocaine affects binding ISO RGD:68520 6480464 Cocaine binds to SIGMAR1 protein CTD PMID:12128006 cocaine affects binding ISO RGD:68519 6480464 Cocaine binds to SIGMAR1 protein CTD PMID:20956312 copper(II) sulfate decreases expression ISO RGD:68519 6480464 Copper Sulfate results in decreased expression of SIGMAR1 mRNA CTD PMID:19549813 cyclosporin A decreases expression ISO RGD:68519 6480464 Cyclosporine results in decreased expression of SIGMAR1 mRNA CTD PMID:20106945 , PMID:25562108 dextromethorphan affects binding EXP 6480464 Dextromethorphan binds to SIGMAR1 protein CTD PMID:15723099 dextromethorphan multiple interactions EXP 6480464 SIGMAR1 protein affects the reaction [Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of FOS mRNA]] more ... CTD PMID:15723099 dibutyl phthalate decreases expression EXP 6480464 Dibutyl Phthalate results in decreased expression of SIGMAR1 mRNA CTD PMID:17379624 dimemorfan multiple interactions EXP 6480464 dimemorfan binds to and results in increased activity of SIGMAR1 protein more ... CTD PMID:15723099 , PMID:18173806 dimemorfan affects binding EXP 6480464 dimemorfan binds to SIGMAR1 protein CTD PMID:15723099 dioxygen decreases expression ISO RGD:68519 6480464 Oxygen deficiency results in decreased expression of SIGMAR1 mRNA CTD PMID:26516004 endosulfan increases expression EXP 6480464 Endosulfan results in increased expression of SIGMAR1 mRNA CTD PMID:29391264 ethanol affects expression ISO RGD:68520 6480464 Ethanol affects the expression of SIGMAR1 mRNA CTD PMID:30319688 flavonoids increases expression EXP 6480464 Flavonoids results in increased expression of SIGMAR1 mRNA CTD PMID:18035473 fluoranthene multiple interactions ISO RGD:68520 6480464 [1-methylanthracene co-treated with fluoranthene] results in decreased expression of SIGMAR1 mRNA CTD PMID:28329830 flutamide decreases expression EXP 6480464 Flutamide results in decreased expression of SIGMAR1 mRNA CTD PMID:24793618 hydrogen cyanide decreases expression ISO RGD:68520 6480464 Hydrogen Cyanide results in decreased expression of SIGMAR1 mRNA CTD PMID:33914522 inulin multiple interactions ISO RGD:68520 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of SIGMAR1 mRNA CTD PMID:36331819 ivermectin decreases expression ISO RGD:68519 6480464 Ivermectin results in decreased expression of SIGMAR1 protein CTD PMID:32959892 kainic acid multiple interactions EXP 6480464 SIGMAR1 protein affects the reaction [Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of FOS mRNA]] more ... CTD PMID:15723099 linuron multiple interactions ISO RGD:68519 6480464 Linuron promotes the reaction [ERN1 protein binds to SIGMAR1 protein] CTD PMID:30661753 linuron multiple interactions ISO RGD:68520 6480464 SIGMAR1 gene mutant form inhibits the reaction [Linuron results in increased expression of ARG1 mRNA] more ... CTD PMID:30661753 linuron decreases response to substance ISO RGD:68520 6480464 SIGMAR1 gene mutant form results in decreased susceptibility to Linuron CTD PMID:30661753 linuron increases activity ISO RGD:68520 6480464 Linuron results in increased activity of SIGMAR1 protein CTD PMID:30661753 manganese(II) chloride increases expression EXP 6480464 manganese chloride results in increased expression of SIGMAR1 protein CTD PMID:25732873 methotrexate affects expression ISO RGD:68520 6480464 Methotrexate affects the expression of SIGMAR1 mRNA CTD PMID:18502557 methyl beta-cyclodextrin multiple interactions ISO RGD:68520 6480464 methyl-beta-cyclodextrin inhibits the reaction [Cocaine results in increased localization of SIGMAR1 protein] CTD PMID:20354174 N-\{2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethyl\}-N-propylpropan-1-amine hydrochloride multiple interactions EXP 6480464 [N more ... CTD PMID:11907181 N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of SIGMAR1 mRNA CTD PMID:17602206 ochratoxin A decreases expression ISO RGD:68519 6480464 ochratoxin A results in decreased expression of SIGMAR1 protein CTD PMID:36587836 ochratoxin A multiple interactions ISO RGD:68519 6480464 ursolic acid inhibits the reaction [ochratoxin A results in decreased expression of SIGMAR1 protein] CTD PMID:36587836 okadaic acid increases expression EXP 6480464 Okadaic Acid results in increased expression of SIGMAR1 protein CTD PMID:26732598 paclitaxel increases expression EXP 6480464 Paclitaxel analog results in increased expression of SIGMAR1 mRNA CTD PMID:15585946 paracetamol multiple interactions ISO RGD:68520 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of SIGMAR1 mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of SIGMAR1 mRNA] CTD PMID:17585979 perfluorooctane-1-sulfonic acid increases expression EXP 6480464 perfluorooctane sulfonic acid results in increased expression of SIGMAR1 mRNA CTD PMID:18692542 perfluorooctane-1-sulfonic acid multiple interactions ISO RGD:68520 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of SIGMAR1 mRNA more ... CTD PMID:36331819 perfluorooctanoic acid decreases expression ISO RGD:68519 6480464 perfluorooctanoic acid results in decreased expression of SIGMAR1 protein CTD PMID:35123991 phenobarbital affects expression ISO RGD:68520 6480464 Phenobarbital affects the expression of SIGMAR1 mRNA CTD PMID:23091169 piperazines affects binding ISO RGD:68520 6480464 Piperazines binds to SIGMAR1 protein CTD PMID:15099923 pirinixic acid decreases expression ISO RGD:68520 6480464 pirinixic acid results in decreased expression of SIGMAR1 mRNA CTD PMID:18445702 pirinixic acid increases expression ISO RGD:68520 6480464 pirinixic acid results in increased expression of SIGMAR1 mRNA CTD PMID:15302862 more ... pirinixic acid multiple interactions ISO RGD:68520 6480464 PPARA protein promotes the reaction [pirinixic acid results in increased expression of SIGMAR1 mRNA] CTD PMID:20059764 potassium cyanide increases expression ISO RGD:68520 6480464 Potassium Cyanide results in increased expression of SIGMAR1 mRNA CTD PMID:33914522 pregnenolone increases abundance ISO RGD:68520 6480464 SIGMAR1 protein results in increased abundance of Pregnenolone CTD PMID:22923735 pregnenolone 16alpha-carbonitrile affects expression EXP 6480464 Pregnenolone Carbonitrile affects the expression of SIGMAR1 mRNA CTD PMID:19162173 resveratrol increases expression ISO RGD:68520 6480464 resveratrol results in increased expression of SIGMAR1 protein CTD PMID:25505154 SCH 23390 multiple interactions ISO RGD:68519 6480464 SCH 23390 inhibits the reaction [Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein]] more ... CTD PMID:20956312 scopolamine multiple interactions ISO RGD:68520 6480464 [2-(4-morpholino)ethyl-1-phenylcyclohexane-1-carboxylate binds to and results in increased activity of SIGMAR1 protein] which results in decreased susceptibility to Scopolamine, [igmesine binds to and results in increased activity of SIGMAR1 protein] which results in decreased susceptibility to Scopolamine CTD PMID:12028363 sodium arsenite increases expression ISO RGD:68519 6480464 sodium arsenite results in increased expression of SIGMAR1 mRNA CTD PMID:34032870 tamoxifen affects expression ISO RGD:68520 6480464 Tamoxifen affects the expression of SIGMAR1 mRNA CTD PMID:17555576 tetrachloromethane affects expression ISO RGD:68520 6480464 Carbon Tetrachloride affects the expression of SIGMAR1 mRNA CTD PMID:31919559 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of SIGMAR1 mRNA CTD PMID:34492290 triphenyl phosphate decreases expression EXP 6480464 triphenyl phosphate results in decreased expression of SIGMAR1 mRNA CTD PMID:30589522 triptonide increases expression ISO RGD:68520 6480464 triptonide results in increased expression of SIGMAR1 mRNA CTD PMID:33045310 ursolic acid multiple interactions ISO RGD:68519 6480464 ursolic acid inhibits the reaction [bardoxolone methyl results in decreased expression of SIGMAR1 protein], ursolic acid inhibits the reaction [ochratoxin A results in decreased expression of SIGMAR1 protein] CTD PMID:36587836 ursolic acid increases expression ISO RGD:68519 6480464 ursolic acid results in increased expression of SIGMAR1 protein CTD PMID:36587836 valproic acid affects expression ISO RGD:68520 6480464 Valproic Acid affects the expression of SIGMAR1 mRNA CTD PMID:17292431 valproic acid decreases methylation ISO RGD:68519 6480464 Valproic Acid results in decreased methylation of SIGMAR1 gene CTD PMID:29154799 valproic acid increases expression ISO RGD:68519 6480464 Valproic Acid results in increased expression of SIGMAR1 mRNA CTD PMID:23179753 valproic acid affects expression ISO RGD:68519 6480464 Valproic Acid affects the expression of SIGMAR1 mRNA CTD PMID:25979313 vinclozolin decreases expression EXP 6480464 vinclozolin results in decreased expression of SIGMAR1 mRNA CTD PMID:23555832 vinclozolin increases expression EXP 6480464 vinclozolin results in increased expression of SIGMAR1 mRNA CTD PMID:22570695