Trim32 (tripartite motif-containing 32) - Rat Genome Database

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Gene: Trim32 (tripartite motif-containing 32) Rattus norvegicus
Analyze
Symbol: Trim32
Name: tripartite motif-containing 32
RGD ID: 1305238
Description: Predicted to enable several functions, including identical protein binding activity; ubiquitin binding activity; and ubiquitin protein ligase activity. Predicted to be involved in several processes, including defense response to other organism; positive regulation of protein metabolic process; and regulation of intracellular signal transduction. Predicted to act upstream of or within several processes, including muscle cell cellular homeostasis; positive regulation of cytokine-mediated signaling pathway; and protein ubiquitination. Predicted to be located in nucleus and striated muscle myosin thick filament. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome; Bardet-Biedl syndrome 11; autosomal recessive limb-girdle muscular dystrophy type 2H; and muscular dystrophy. Orthologous to human TRIM32 (tripartite motif containing 32); PARTICIPATES IN ubiquitin/proteasome degradation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; amphetamine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: E3 ubiquitin-protein ligase TRIM32; LOC313264; MGC109467; tripartite motif protein 32
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2579,005,139 - 79,016,615 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl578,999,389 - 79,022,018 (+)Ensembl
Rnor_6.0581,431,554 - 81,449,023 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl581,431,600 - 81,442,451 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0585,530,347 - 85,541,240 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4582,380,439 - 82,391,290 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1582,385,551 - 82,396,402 (+)NCBI
Celera577,919,712 - 77,930,564 (+)NCBICelera
Cytogenetic Map5q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
actin ubiquitination  (ISO)
axon development  (ISO)
biological_process  (ND)
fat cell differentiation  (ISO)
free ubiquitin chain polymerization  (ISO)
innate immune response  (ISO)
muscle cell cellular homeostasis  (ISO)
negative regulation of fibroblast proliferation  (ISO)
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage  (ISO)
negative regulation of viral transcription  (ISO)
positive regulation of autophagy  (ISO)
positive regulation of cell cycle  (ISO)
positive regulation of cell growth  (ISO)
positive regulation of cell migration  (ISO)
positive regulation of cell motility  (ISO)
positive regulation of chemokine (C-C motif) ligand 20 production  (ISO)
positive regulation of DNA-binding transcription factor activity  (ISO)
positive regulation of DNA-templated transcription  (IEA)
positive regulation of I-kappaB kinase/NF-kappaB signaling  (ISO)
positive regulation of interleukin-17-mediated signaling pathway  (ISO)
positive regulation of neurogenesis  (ISO)
positive regulation of neuron differentiation  (ISO)
positive regulation of NF-kappaB transcription factor activity  (IBA,ISO)
positive regulation of protein catabolic process  (ISO,ISS)
positive regulation of proteolysis  (ISO)
positive regulation of striated muscle cell differentiation  (ISO)
positive regulation of tumor necrosis factor-mediated signaling pathway  (ISO)
protein K48-linked ubiquitination  (IBA)
protein polyubiquitination  (ISO)
protein ubiquitination  (ISO)
response to tumor necrosis factor  (ISO)
response to UV  (ISO)
suppression of viral release by host  (ISO)
tissue homeostasis  (ISO)
ubiquitin-dependent protein catabolic process  (ISO)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Homozygosity mapping with SNP arrays identifies TRIM32, an E3 ubiquitin ligase, as a Bardet-Biedl syndrome gene (BBS11). Chiang AP, etal., Proc Natl Acad Sci U S A. 2006 Apr 18;103(16):6287-92. Epub 2006 Apr 10.
2. Limb-girdle muscular dystrophy type 2H associated with mutation in TRIM32, a putative E3-ubiquitin-ligase gene. Frosk P, etal., Am J Hum Genet. 2002 Mar;70(3):663-72. Epub 2002 Jan 29.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. GOA pipeline RGD automated data pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:11331580   PMID:12477932   PMID:16243356   PMID:16816390   PMID:17379567   PMID:18248090   PMID:18632609   PMID:19155210   PMID:19269368   PMID:19349376   PMID:20054338   PMID:21775502  
PMID:22299041   PMID:22493164   PMID:22871113   PMID:23077300   PMID:25416956   PMID:26884348   PMID:28025799   PMID:28465353   PMID:28933219   PMID:30361391   PMID:31410708   PMID:31967859  
PMID:34888944  


Genomics

Comparative Map Data
Trim32
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2579,005,139 - 79,016,615 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl578,999,389 - 79,022,018 (+)Ensembl
Rnor_6.0581,431,554 - 81,449,023 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl581,431,600 - 81,442,451 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0585,530,347 - 85,541,240 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4582,380,439 - 82,391,290 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1582,385,551 - 82,396,402 (+)NCBI
Celera577,919,712 - 77,930,564 (+)NCBICelera
Cytogenetic Map5q24NCBI
TRIM32
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389116,687,305 - 116,701,299 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl9116,687,305 - 116,701,300 (+)EnsemblGRCh38hg38GRCh38
GRCh379119,449,584 - 119,463,578 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369118,489,402 - 118,503,400 (+)NCBINCBI36hg18NCBI36
Build 349116,529,162 - 116,542,582NCBI
Celera990,097,223 - 90,111,221 (+)NCBI
Cytogenetic Map9q33.1NCBI
HuRef989,054,928 - 89,068,929 (+)NCBIHuRef
CHM1_19119,596,015 - 119,610,013 (+)NCBICHM1_1
T2T-CHM13v2.09128,880,322 - 128,894,320 (+)NCBI
Trim32
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39465,523,223 - 65,534,477 (+)NCBIGRCm39mm39
GRCm39 Ensembl465,523,223 - 65,534,475 (+)Ensembl
GRCm38465,604,986 - 65,616,240 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl465,604,986 - 65,616,238 (+)EnsemblGRCm38mm10GRCm38
MGSCv37465,266,020 - 65,277,274 (+)NCBIGRCm37mm9NCBIm37
MGSCv36465,091,379 - 65,102,599 (+)NCBImm8
Celera464,238,387 - 64,249,387 (+)NCBICelera
Cytogenetic Map4C1NCBI
cM Map434.43NCBI
Trim32
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541911,151,751 - 11,168,041 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541911,151,751 - 11,168,046 (-)NCBIChiLan1.0ChiLan1.0
TRIM32
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.19116,173,546 - 116,187,300 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9116,183,746 - 116,185,707 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0987,819,723 - 87,838,684 (+)NCBIMhudiblu_PPA_v0panPan3
TRIM32
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11170,453,130 - 70,465,030 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1170,462,007 - 70,463,974 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1168,861,539 - 68,873,667 (+)NCBI
ROS_Cfam_1.01171,578,469 - 71,590,603 (+)NCBI
ROS_Cfam_1.0 Ensembl1171,578,495 - 71,590,597 (+)Ensembl
UMICH_Zoey_3.11170,098,438 - 70,110,545 (+)NCBI
UNSW_CanFamBas_1.01170,132,364 - 70,144,497 (+)NCBI
UU_Cfam_GSD_1.01170,863,600 - 70,875,730 (+)NCBI
Trim32
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947185,838,158 - 185,861,448 (+)NCBI
SpeTri2.0NW_0049364875,606,690 - 5,619,856 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRIM32
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1257,054,227 - 257,066,910 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11257,051,421 - 257,066,911 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21288,450,251 - 288,461,926 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TRIM32
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11222,893,689 - 22,906,913 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1222,894,886 - 22,896,847 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603519,970,768 - 19,983,855 (+)NCBIVero_WHO_p1.0
Trim32
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476018,585,279 - 18,599,659 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462476018,577,764 - 18,600,869 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
BF387417  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2579,008,729 - 79,008,880 (+)MAPPERmRatBN7.2
Rnor_6.0581,435,162 - 81,435,312NCBIRnor6.0
Rnor_5.0585,533,951 - 85,534,101UniSTSRnor5.0
RGSC_v3.4582,384,001 - 82,384,151UniSTSRGSC3.4
Celera577,923,274 - 77,923,424UniSTS
RH 3.4 Map5616.7UniSTS
Cytogenetic Map5q24UniSTS
UniSTS:234940  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2579,014,897 - 79,015,053 (+)MAPPERmRatBN7.2
Rnor_6.0581,441,330 - 81,441,485NCBIRnor6.0
Rnor_5.0585,540,119 - 85,540,274UniSTSRnor5.0
RGSC_v3.4582,390,169 - 82,390,324UniSTSRGSC3.4
Celera577,929,443 - 77,929,598UniSTS
Cytogenetic Map5q24UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)5190450412Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51131345958Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)572947086724018Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
7394712Emca13Estrogen-induced mammary cancer QTL 13mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)5982326699753708Rat
634305Mamtr1Mammary tumor resistance QTL 10.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)512789751113558310Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)531663789131345958Rat
1576317Eutr2Estrogen induced uterine response QTL 20.01uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)534730116104251008Rat
2316959Gluco59Glucose level QTL 594.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)534944474113558310Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)535189153141643988Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
1331773Scl26Serum cholesterol level QTL 263.065blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)54372665686724018Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)543726656129132602Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
1300115Hrtrt7Heart rate QTL 72.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)54786906290099692Rat
9589025Epfw7Epididymal fat weight QTL 720.660.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)54946360094463600Rat
7411561Bw134Body weight QTL 134240.001body mass (VT:0001259)body weight gain (CMO:0000420)54946360094463600Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)550328551141643988Rat
2303615Vencon7Ventilatory control QTL 70.001respiration trait (VT:0001943)respiration rate (CMO:0000289)55098389595983895Rat
2303574Gluco42Glucose level QTL 422blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)55349671998496719Rat
61359EaexExperimental allergic encephalomyelitis QTL x3nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)555715622100715622Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555805606132207589Rat
1358895Bp254Blood pressure QTL 2543.60.0003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)558829236128034027Rat
61426Scl2Serum cholesterol level QTL 27.30.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)559793399143070159Rat
2316954Rf57Renal function QTL 570kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)55979352890450144Rat
2316957Pur21Proteinuria QTL 216.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)559793528113558156Rat
61386Bp49Blood pressure QTL 4916.6cerebrum integrity trait (VT:0010549)brain infarction volume (CMO:0001013)56029343498603051Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)560293434161481680Rat
2290005Mcs24Mammary carcinoma susceptibility QTL 24mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)564719390109719390Rat
2306971Anxrr21Anxiety related response QTL 219.47fear/anxiety-related behavior trait (VT:1000241)number of entries into a discrete space in an experimental apparatus (CMO:0000960)566174080124160948Rat
2312671Scl64Serum cholesterol level QTL 640.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)568984307104251008Rat
61380Edpm5Estrogen-dependent pituitary mass QTL 54.50.92pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)568984307104251008Rat
1357396Bw44Body weight QTL 444.19body mass (VT:0001259)body weight (CMO:0000012)568984307104251008Rat
1357402Bw46Body weight QTL 464.47body mass (VT:0001259)body mass index (BMI) (CMO:0000105)568984307104251008Rat
2302381Bw84Body weight QTL 844.47body mass (VT:0001259)body mass index (BMI) (CMO:0000105)568984307104251008Rat
1354598Srn6Serum renin concentration QTL 63.8blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)569540295151018848Rat
1598845Mcs14Mammary carcinoma susceptibility QTL 140.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)57636977680813390Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:400
Count of miRNA genes:206
Interacting mature miRNAs:266
Transcripts:ENSRNOT00000013675
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 26 16 6 2 6 74 35 39 11
Low 3 17 41 35 17 35 8 11 2 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000013675   ⟹   ENSRNOP00000013675
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl579,005,182 - 79,016,013 (+)Ensembl
Rnor_6.0 Ensembl581,431,600 - 81,442,451 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000097652   ⟹   ENSRNOP00000083581
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl578,999,389 - 79,022,018 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000117373   ⟹   ENSRNOP00000086314
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl579,005,132 - 79,022,018 (+)Ensembl
RefSeq Acc Id: NM_001012103   ⟹   NP_001012103
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2579,005,168 - 79,016,019 (+)NCBI
Rnor_6.0581,431,600 - 81,442,451 (+)NCBI
Rnor_5.0585,530,347 - 85,541,240 (+)NCBI
RGSC_v3.4582,380,439 - 82,391,290 (+)RGD
Celera577,919,712 - 77,930,564 (+)RGD
Sequence:
RefSeq Acc Id: XM_006238270   ⟹   XP_006238332
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2579,005,139 - 79,016,615 (+)NCBI
Rnor_6.0581,431,554 - 81,449,023 (+)NCBI
Rnor_5.0585,530,347 - 85,541,240 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001012103 (Get FASTA)   NCBI Sequence Viewer  
  XP_006238332 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH81980 (Get FASTA)   NCBI Sequence Viewer  
  AAH91385 (Get FASTA)   NCBI Sequence Viewer  
  EDM10507 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001012103   ⟸   NM_001012103
- UniProtKB: Q66H79 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006238332   ⟸   XM_006238270
- Peptide Label: isoform X1
- UniProtKB: Q66H79 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000013675   ⟸   ENSRNOT00000013675
RefSeq Acc Id: ENSRNOP00000083581   ⟸   ENSRNOT00000097652
RefSeq Acc Id: ENSRNOP00000086314   ⟸   ENSRNOT00000117373
Protein Domains
B box-type   RING-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q66H79-F1-model_v2 AlphaFold Q66H79 1-655 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693806
Promoter ID:EPDNEW_R4331
Type:initiation region
Name:Trim32_1
Description:tripartite motif-containing 32
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0581,431,619 - 81,431,679EPDNEW

Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305238 AgrOrtholog
BioCyc Gene G2FUF-41038 BioCyc
Ensembl Genes ENSRNOG00000010303 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000013675.4 UniProtKB/TrEMBL
  ENSRNOP00000083581.1 UniProtKB/TrEMBL
  ENSRNOP00000086314 ENTREZGENE
  ENSRNOP00000086314.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000013675.6 UniProtKB/TrEMBL
  ENSRNOT00000097652.1 UniProtKB/TrEMBL
  ENSRNOT00000117373 ENTREZGENE
  ENSRNOT00000117373.1 UniProtKB/TrEMBL
Gene3D-CATH 2.120.10.30 UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7128474 IMAGE-MGC_LOAD
  IMAGE:7321183 IMAGE-MGC_LOAD
InterPro 6-blade_b-propeller_TolB-like UniProtKB/TrEMBL
  NHL_repeat UniProtKB/TrEMBL
  zf-RING_LisH UniProtKB/TrEMBL
  Znf_B-box UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/TrEMBL
KEGG Report rno:313264 UniProtKB/TrEMBL
MGC_CLONE MGC:109467 IMAGE-MGC_LOAD
  MGC:94163 IMAGE-MGC_LOAD
NCBI Gene 313264 ENTREZGENE
Pfam NHL UniProtKB/TrEMBL
  zf-RING_LisH UniProtKB/TrEMBL
PhenoGen Trim32 PhenoGen
PROSITE NHL UniProtKB/TrEMBL
  ZF_BBOX UniProtKB/TrEMBL
  ZF_RING_1 UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
SMART BBOX UniProtKB/TrEMBL
  RING UniProtKB/TrEMBL
UniProt F7F4N6_RAT UniProtKB/TrEMBL
  Q66H79 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2009-05-01 Trim32  tripartite motif-containing 32  Trim32  tripartite motif protein 32  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Trim32  tripartite motif protein 32  Trim32_predicted  tripartite motif protein 32 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Trim32_predicted  tripartite motif protein 32 (predicted)      Symbol and Name status set to approved 70820 APPROVED