Tmem215 (transmembrane protein 215)

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Gene: Tmem215 (transmembrane protein 215) Rattus norvegicus

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Symbol:

Tmem215

Name:

transmembrane protein 215

RGD ID:

1589861

Description:

Predicted to act upstream of or within negative regulation of retinal cell programmed cell death and sprouting angiogenesis. Orthologous to human TMEM215 (transmembrane protein 215); INTERACTS WITH bisphenol A; glycidol; glyphosate.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

hypothetical protein LOC690918; LOC690918; uncharacterized protein LOC690918

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TMEM215 (transmembrane protein 215)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Tmem215 (transmembrane protein 215)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Tmem215 (transmembrane protein 215)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TMEM215 (transmembrane protein 215)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TMEM215 (transmembrane protein 215)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Tmem215 (transmembrane protein 215)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TMEM215 (transmembrane protein 215)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TMEM215 (transmembrane protein 215)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Tmem215 (transmembrane protein 215)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	PDCD5 (programmed cell death 5)	HGNC	OMA
Alliance orthologs ³
Mus musculus (house mouse):	Tmem215 (transmembrane protein 215)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	TMEM215 (transmembrane protein 215)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	tmem215	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	60,408,587 - 60,411,841 (+)	NCBI		GRCr8
mRatBN7.2	5	55,612,568 - 55,615,828 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	55,612,568 - 55,615,828 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	57,578,365 - 57,581,600 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	59,397,503 - 59,400,738 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	59,378,202 - 59,381,452 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	56,797,502 - 56,800,759 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	56,797,502 - 56,800,759 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	61,336,232 - 61,339,489 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	57,896,391 - 57,899,650 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	5	54,225,999 - 54,229,256 (+)	NCBI		Celera
Cytogenetic Map	5	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

acromesomelic dysplasia, Maroteaux type (ISO)

distal arthrogryposis type 1A (ISO)

frontotemporal dementia and/or amyotrophic lateral sclerosis 6 (ISO)

galactosemia (ISO)

primary ciliary dyskinesia (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

aflatoxin B1 (ISO)

benzo[a]pyrene (ISO)

Benzo[k]fluoranthene (ISO)

bisphenol A (EXP,ISO)

folic acid (ISO)

glycidol (EXP)

glyphosate (EXP)

lipopolysaccharide (ISO)

nickel sulfate (ISO)

potassium chromate (ISO)

resveratrol (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

titanium dioxide (ISO)

triclosan (ISO)

triptonide (ISO)

zearalenone (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

angiogenesis (ISO)

negative regulation of retinal cell programmed cell death (ISO)

sprouting angiogenesis (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data

Tmem215
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	60,408,587 - 60,411,841 (+)	NCBI		GRCr8
mRatBN7.2	5	55,612,568 - 55,615,828 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	55,612,568 - 55,615,828 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	57,578,365 - 57,581,600 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	59,397,503 - 59,400,738 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	59,378,202 - 59,381,452 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	56,797,502 - 56,800,759 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	56,797,502 - 56,800,759 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	61,336,232 - 61,339,489 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	57,896,391 - 57,899,650 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	5	54,225,999 - 54,229,256 (+)	NCBI		Celera
Cytogenetic Map	5	q22	NCBI

TMEM215
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	9	32,783,540 - 32,789,201 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	9	32,783,540 - 32,789,201 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	9	32,783,538 - 32,789,199 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	32,773,497 - 32,779,199 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	9	32,714,718 - 32,720,420 (+)	NCBI		Celera
Cytogenetic Map	9	p21.1	NCBI
HuRef	9	32,741,903 - 32,747,605 (+)	NCBI		HuRef
CHM1_1	9	32,783,637 - 32,789,339 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	9	32,799,741 - 32,805,402 (+)	NCBI		T2T-CHM13v2.0

Tmem215
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	40,472,180 - 40,475,653 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	40,472,180 - 40,477,168 (+)	Ensembl		GRCm39 Ensembl
GRCm38	4	40,472,180 - 40,475,653 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	40,472,180 - 40,477,168 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	40,419,213 - 40,422,686 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	40,660,851 - 40,664,324 (+)	NCBI		MGSCv36	mm8
Celera	4	40,132,937 - 40,136,380 (+)	NCBI		Celera
Cytogenetic Map	4	A5	NCBI
cM Map	4	20.28	NCBI

Tmem215
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955472	2,875,398 - 2,879,115 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955472	2,875,398 - 2,879,115 (-)	NCBI	ChiLan1.0	ChiLan1.0

TMEM215
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	11	91,818,545 - 91,826,514 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	9	91,824,510 - 91,832,456 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	9	32,557,141 - 32,563,166 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	9	33,368,774 - 33,374,476 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	9	33,369,459 - 33,370,166 (+)	Ensembl	panpan1.1		panPan2

TMEM215
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	11	49,980,861 - 49,983,122 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	11	48,602,715 - 48,608,885 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	11	50,921,425 - 50,927,595 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	11	50,922,356 - 50,923,060 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	11	49,584,800 - 49,590,624 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	11	49,451,295 - 49,457,469 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	11	50,209,679 - 50,215,853 (+)	NCBI		UU_Cfam_GSD_1.0

Tmem215
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	164,851,397 - 164,854,654 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936524	1,400,526 - 1,401,233 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936524	1,395,860 - 1,402,013 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TMEM215
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	10	33,664,793 - 33,670,295 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	10	33,663,263 - 33,670,510 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	10	37,921,397 - 37,923,941 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TMEM215
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	12	47,487,134 - 47,491,507 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	12	47,489,038 - 47,489,745 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	44,380,696 - 44,384,432 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tmem215
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624736	37,447,724 - 37,449,951 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624736	37,447,855 - 37,450,366 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Tmem215
32 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	42
Count of miRNA genes:	36
Interacting mature miRNAs:	37
Transcripts:	ENSRNOT00000067992
Prediction methods:	Microtar, Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1298067	Scl15	Serum cholesterol level QTL 15	4.8	0.001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	33215665	78215665	Rat
1300115	Hrtrt7	Heart rate QTL 7	2.76		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	5	47869062	90099692	Rat
1578776	Stresp18	Stress response QTL 18	2.9		thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	5	27955440	72955440	Rat
1549845	Scl44	Serum cholesterol level QTL 44	6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	40128307	148607290	Rat
70212	Niddm25	Non-insulin dependent diabetes mellitus QTL 25	3.54		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	5	1	131345958	Rat
1358353	Srcrtb2	Stress Responsive Cort Basal QTL 2	3.48	0.003	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	5	18873947	74251464	Rat
634305	Mamtr1	Mammary tumor resistance QTL 1		0.0001	mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	12789751	113558310	Rat
1331801	Rf33	Renal function QTL 33	4.149		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	5	43726656	129132602	Rat
1598807	Glom12	Glomerulus QTL 12	2.7		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	5	33215665	78215665	Rat
1302786	Kidm8	Kidney mass QTL 8	28.15		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	5	33215665	78215665	Rat
6903292	Stl28	Serum triglyceride level QTL 28	2.6	0.0073	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	5	28515489	73515489	Rat
1578766	Tcas11	Tongue tumor susceptibility QTL 11	4.12		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	5	46711509	161317411	Rat
1578767	Stresp17	Stress response QTL 17	4.3	0.01	blood aldosterone amount (VT:0005346)	plasma aldosterone level (CMO:0000551)	5	27955440	72955440	Rat
7411561	Bw134	Body weight QTL 134	24	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	49463600	94463600	Rat
1641922	Alcrsp8	Alcohol response QTL 8			alcohol metabolism trait (VT:0015089)	blood ethanol level (CMO:0000535)	5	35189153	68564008	Rat
2303615	Vencon7	Ventilatory control QTL 7		0.001	respiration trait (VT:0001943)	respiration rate (CMO:0000289)	5	50983895	95983895	Rat
1576312	Emca8	Estrogen-induced mammary cancer QTL 8	4.1		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	50328551	141643988	Rat
1641912	Alcrsp18	Alcohol response QTL 18			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	5	35189153	141643988	Rat
1576314	Eutr1	Estrogen induced uterine response QTL 1			uterus integrity trait (VT:0010575)	pyometritis severity score (CMO:0002009)	5	2138965	166875058	Rat
6903306	Scl35	Serum cholesterol QTL 35	2.6	0.0073	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	28515489	73515489	Rat
1576317	Eutr2	Estrogen induced uterine response QTL 2		0.01	uterus integrity trait (VT:0010575)	pyometritis severity score (CMO:0002009)	5	34730116	104251008	Rat
7394712	Emca13	Estrogen-induced mammary cancer QTL 13			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	9823266	99753708	Rat
1331773	Scl26	Serum cholesterol level QTL 26	3.065		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	43726656	86724018	Rat
1331771	Rf35	Renal function QTL 35	4.36965		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	5	729470	86724018	Rat
2290448	Scl54	Serum cholesterol level QTL 54	2.93		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	31663789	131345958	Rat
8662454	Vetf3	Vascular elastic tissue fragility QTL 3	27.4		artery integrity trait (VT:0010639)	number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)	5	2282226	69540447	Rat
9589025	Epfw7	Epididymal fat weight QTL 7	20.66	0.001	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	5	49463600	94463600	Rat
2303574	Gluco42	Glucose level QTL 42	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	5	53496719	98496719	Rat
1641903	Alcrsp3	Alcohol response QTL 3			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	5	12689285	57689285	Rat
1331756	Rf34	Renal function QTL 34	4.16275		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	5	1	90450412	Rat
8552954	Pigfal14	Plasma insulin-like growth factor 1 level QTL 14	9		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	21226744	66226744	Rat
2316959	Gluco59	Glucose level QTL 59	4.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	5	34944474	113558310	Rat
1600358	Mamtr5	Mammary tumor resistance QTL 5			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	18873947	63873947	Rat

Markers in Region

BE109914

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	55,615,253 - 55,615,404 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	56,800,185 - 56,800,335	NCBI	Rnor6.0
Rnor_5.0	5	61,338,915 - 61,339,065	UniSTS	Rnor5.0
RGSC_v3.4	5	57,899,076 - 57,899,226	UniSTS	RGSC3.4
Celera	5	54,228,682 - 54,228,832	UniSTS
Cytogenetic Map	5	q22	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
7	4	49	104	35	43	12	25	12	6	140	82	93	36	50	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001109613	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473962	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000067992 ⟹ ENSRNOP00000060159

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	55,612,568 - 55,615,828 (+)	Ensembl
Rnor_6.0 Ensembl	5	56,797,502 - 56,800,759 (+)	Ensembl

RefSeq Acc Id:

NM_001109613 ⟹ NP_001103083

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	60,408,587 - 60,411,841 (+)	NCBI
mRatBN7.2	5	55,612,568 - 55,615,828 (+)	NCBI
Rnor_6.0	5	56,797,502 - 56,800,759 (+)	NCBI
Rnor_5.0	5	61,336,232 - 61,339,489 (+)	NCBI
RGSC_v3.4	5	57,896,391 - 57,899,650 (+)	RGD
Celera	5	54,225,999 - 54,229,256 (+)	RGD

Sequence:

show sequence

GTCTCCGATGGTTTGGATCCTGCCTTTCATGTGGAGAGCACTACCATCATACTAGGAGAAGAAA
AGAGTATGCCTTTCTGTGTATTTTGAACAGGAACCACGCACCAAAGCCTGGTGCTAGGAATTTA
CACTTCTGTAATAGTCGCAGCGTTTGCTCAGACATTTGGTGTTAATAGTCTCCTGATGACTGAT
TGTCAGAAAGGTGAGATCACTCATTCTGGTAAGCATGACCAGCTTAGGTGGAGAAGACCTGGAT
GCCAAAATTTTTTCCTCCAAATCAGAAACTCGGCAAGAAAGGATGTACCTTTTGCCTTCCTAAT
TCCCTTCCTCTACCTTAAACAGACCCGGTGAAGGATCTCAGCCACATCCAGTCCTCCCTCGGGA
CAAGGGAACCCTTACACTTCTTTGGGTGGACCCTGGACTGAGACTAGCACTGGGCTGTCAGCAA
GACAGGATAGAATCTTGTCTCCTGGTTGTGCCTGACCCTCCAAACCAAAGTCTGTCCTGCGGGC
TACCTGGTCGTCGACCCTGTTTGAAGATCAAAACCAGGAGCCCTTCTTCCTTGCCTCAGTCGGT
GTGGTTGGAACCACGACTGTGGGACTGAGTTTCCAAGGCTACTTTCTGGAATGGGAGTCCAGCA
GAGATGCGGGTGACTTCTCCTAGGCAGAGGCAGGACCTGCTACCCAGCTTCTTCGAGGCTATCT
TGCGCGTGGTCCCTGAATTTGGAACTCAGACGGTGCATCAGCGGCCCCGTGGGCAAGGCGCTCT
GGACTCCGGCAGCGGCACGGACACGGGTCCAAGCCACCTGCCCGCTGCATCGCGACGAGAGCCC
CCAGCAGCGGCTTCCCGAGGCCGCTGGGCTCTGACCCCCTCGCGCCCCCGCGCGTCCATCTCTG
TTCCCAGCGCGGTGCAAGTGATGTAAGGCGGCCAGGCTCGCGCGTTTTTTCCTGCCGGGACGGA
GTCCTCCCTCCTCGCTGGCAGCGCCGCGCGCCCACTCCGATCCGCTGCGCCCAGGTTCCCAGGT
TCCGCTTCCTGAGCTCTGGCGACTGCTCGCAGCTGCTGGGAAAGACCCTCCTCCCCTATCCCAC
CTCCTTCCTCTCCTCCCCACCCTGCTCCTGTGCAGTGTTGGTGGGGAAAACCAGGCTTGGCTCT
CAGAATCCAAGGAGAGAACCGAGGGACAGCTAACTGGAGACGCTGAGAGGTGGCAGGAACCTTC
AGAAAAGGAAAAGGGGTACTTTCTGGCTACCAGGCAGCCCCCAACCTGGATGGAGTAAAAGATG
AGACCTGATGACATAAATCCGAGGACTGGGCTGGTGGTGGCCCTGGTCAGTGTTTTTCTGGTCT
TTGGTTTCATGTTCACTGTCTCTGGCATGAAGGGGGAAACTCTGGGGAACATCCCTCTGTTGGC
CATTGGGCCAGCCATCTGCCTTCCAGGCATTGCGGCCATTGCTCTGGCCAGGAAAACCGAAGGC
TGCACCAAATGGCCGGAGAACGAGCTACTGTGGGTCCGCAAGTTGCCCTGCTTCAGGAAGCCCA
AGGACAAGGAAGTAGTGGAACTCCTGAGGACCCCATCAGACCTGGAGTCCGGCAAGGGGAGCTC
CGATGAACTGGCTAAGAAGGCAGGCCTCAGAGGCAAGCAGCTCCCACAGGGACCAGGTGAGGTG
CCTATGGCCAGCTCCATTACTACCCCAACTCCCACAGAGGAAGGAGAATGCCAGAGTCTAGTTC
AGAGTGGGAGGCAGGAGGAGACATCCAGATATCTGGATGGCTACTGCCCGTCGGCCAGTTCCCT
CGCCTACAGTGCCTTGGATGCCAAGTGCTCAGGCTGGGACAGATCTGACCGCCCTGAACCCGAG
GACAGCATCTTCTTTGTGCCCCAGGACAGTATCATCGTTTGCTCCTACAAGCAAAACAGCCCCT
ATGACAGATACTGTTGCTACATCAACCAGAGCCAAGGCAGGTGGGACCACGAGACAATAGTCTG
ACCTGTTCACACAAGGGTCCCATGTTGACAGACACGCTGCTCTACTCAGCTCCCAAGGGAAGAG
CATCTCTGCTCCGACAGCCTTCACACTGTTAGGAACTGGCATGGTATGTGATGGGGTGCAGACC
TCTGGTGCCTGATACTCGTGTAAATAGGCATGTTGGGGGCATATTTTAGGGAAGTACAGAGAAT
TAAGGACAGTGAGAAGAGGCAGGAAACAGAAAAGAAAGTTCGGTCTGCTTCTGAACAAAGTAAA
CGATGTTGAATGCTTTGTAAAACAGTCCCAAAAGTGTTGGTCATCAGGGGAGTCTAGAGGGCTT
CAGCTGCCGGGTATCAAAGGCTGCAGGAGCTATTCACACAGAAACTGACTGCTTTGCGTCTGAA
GAATGTGAAGGAAAATTGTATGGTCCTTCGTATGATTTTTTTTTTTTTTTTGTCCGTTGATAGC
TTTCCACACGTGGTAATTGCTGAGGCATTACAAACTCAAGATAGAATAGGTAAATCGTCCTGAT
ATGTTATGGGTTTTGGAGTGAAAGGAGTTAAAAATCGTTGGAATGTATAATGGAATCCTGACCT
CTGACAAGATCCTGGTTTCAAATAAAGTGTTGATTATGTTATGTGAAACGTTAATATTTTTTTA
GGTGGTCGTGTTACTTATTAATTCATTTAAATTGAGTTGCTGGAACTTTATCTGAAGTTTTTAA
AAATATTTATTAAGATTAATGTATTTCCTTACCGGGTGCAAAATGACTTGATGTGATATTTTCA
CGGATTAGGATTTCTTCTTATCAGTTCATAAAACAAATTTTACAAAATGCCTTGAACATTTCCG
GGAGGCATGTACTAGGAATTACTATATCCCTTTAAAGTATGAAAGTACAAGTTAATCCTGTAGT
CCTGAGCATTATGAAAAATTTGTATAAGATGTGACAGTTAGGCCTCTGGAAATGCTGTACATTT
GTTCAACAGCACCCCTCCCCCCAACTATGACCGAGACTGCAATGAAACAAGAGTTAATTT

hide sequence

Protein Sequences


Protein RefSeqs	NP_001103083	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL98635	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000060159.1

RefSeq Acc Id:

NP_001103083 ⟸ NM_001109613

- UniProtKB:

D3ZI94 (UniProtKB/TrEMBL), A6IIR5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MRPDDINPRTGLVVALVSVFLVFGFMFTVSGMKGETLGNIPLLAIGPAICLPGIAAIALARKTE
GCTKWPENELLWVRKLPCFRKPKDKEVVELLRTPSDLESGKGSSDELAKKAGLRGKQLPQGPGE
VPMASSITTPTPTEEGECQSLVQSGRQEETSRYLDGYCPSASSLAYSALDAKCSGWDRSDRPEP
EDSIFFVPQDSIIVCSYKQNSPYDRYCCYINQSQGRWDHETIV

hide sequence

Ensembl Acc Id:

ENSRNOP00000060159 ⟸ ENSRNOT00000067992

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZI94-F1-model_v2	AlphaFold	D3ZI94	1-235	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1589861	AgrOrtholog
BioCyc Gene	G2FUF-41594	BioCyc
Ensembl Genes	ENSRNOG00000042246	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000067992.2	UniProtKB/TrEMBL
InterPro	TMEM215	UniProtKB/TrEMBL
KEGG Report	rno:690918	UniProtKB/TrEMBL
NCBI Gene	690918	ENTREZGENE
PANTHER	PTHR31922	UniProtKB/TrEMBL
	TRANSMEMBRANE PROTEIN 215	UniProtKB/TrEMBL
Pfam	TMEM215	UniProtKB/TrEMBL
PhenoGen	Tmem215	PhenoGen
RatGTEx	ENSRNOG00000042246	RatGTEx
UniProt	A6IIR5	ENTREZGENE, UniProtKB/TrEMBL
	D3ZI94	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-07-21	Tmem215	transmembrane protein 215	LOC690918	hypothetical protein LOC690918	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-01-09	LOC690918	hypothetical protein LOC690918	LOC683829	hypothetical protein LOC683829	Data merged from RGD:1597850	1643240	APPROVED
2006-11-20	LOC690918	hypothetical protein LOC690918			Symbol and Name status set to provisional	70820	PROVISIONAL
2006-11-20	LOC683829	hypothetical protein LOC683829			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar