Shb (SH2 domain containing adaptor protein B)

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Gene: Shb (SH2 domain containing adaptor protein B) Rattus norvegicus

Analyze

Symbol:

Shb

Name:

SH2 domain containing adaptor protein B

RGD ID:

1565350

Description:

Predicted to enable phosphotyrosine residue binding activity. Predicted to act upstream of or within several processes, including hematopoietic stem cell proliferation; negative regulation of oocyte maturation; and positive regulation of immune response. Predicted to be located in cytoplasmic ribonucleoprotein granule; cytosol; and nucleoplasm. Orthologous to human SHB (SH2 domain containing adaptor protein B); PARTICIPATES IN platelet-derived growth factor signaling pathway; vascular endothelial growth factor signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

LOC362513; RGD1565350; SH2 domain-containing adapter protein B; similar to Shb protein; Src homology 2 domain containing adaptor protein B

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	5	59,678,066 - 59,785,443 (-)	NCBI	mRatBN7.2
mRatBN7.2 Ensembl	5	59,678,216 - 59,785,538 (-)	Ensembl
Rnor_6.0	5	60,970,650 - 61,077,881 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	60,971,257 - 61,077,627 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	65,479,290 - 65,587,205 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	61,983,643 - 62,090,620 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
Celera	5	58,246,193 - 58,353,269 (-)	NCBI		Celera
Cytogenetic Map	5	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

3,3',4,4'-tetrachlorobiphenyl (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (EXP)

afimoxifene (ISO)

aflatoxin B1 (ISO)

antimycin A (ISO)

atrazine (ISO)

azathioprine (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

benzo[e]pyrene (ISO)

bisphenol A (ISO)

bisphenol F (ISO)

cadmium dichloride (ISO)

carbon nanotube (ISO)

crocidolite asbestos (ISO)

cyclosporin A (ISO)

decabromodiphenyl ether (EXP)

diazinon (ISO)

dioxygen (ISO)

dorsomorphin (ISO)

elemental selenium (ISO)

endosulfan (EXP)

entinostat (ISO)

ethyl methanesulfonate (ISO)

fulvestrant (ISO)

leflunomide (EXP,ISO)

methapyrilene (ISO)

methotrexate (ISO)

methyl methanesulfonate (ISO)

methylmercury chloride (ISO)

panobinostat (ISO)

paracetamol (EXP,ISO)

pentachlorophenol (ISO)

phenylmercury acetate (ISO)

pirinixic acid (ISO)

pregnenolone 16alpha-carbonitrile (ISO)

raloxifene (ISO)

resveratrol (ISO)

SB 431542 (ISO)

selenium atom (ISO)

sodium arsenite (ISO)

tamoxifen (ISO)

tetrachloromethane (ISO)

thapsigargin (ISO)

trichostatin A (ISO)

triclosan (ISO)

triptonide (ISO)

urethane (ISO)

valproic acid (ISO)

vinclozolin (EXP)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

B cell proliferation (ISO)

blood vessel development (ISO)

blood vessel morphogenesis (ISO)

hematopoietic stem cell proliferation (ISO)

hemopoiesis (ISO)

negative regulation of oocyte maturation (ISO)

negative regulation of protein kinase activity (ISO)

positive regulation of mitotic cell cycle (ISO)

positive regulation of T-helper cell differentiation (ISO)

T cell receptor signaling pathway (ISO)

Cellular Component

cytoplasmic ribonucleoprotein granule (IEA,ISO)

cytosol (IEA,ISO)

nucleoplasm (IEA,ISO)

Molecular Function

phosphotyrosine residue binding (IBA,ISO)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

platelet-derived growth factor signaling pathway (ISO)

vascular endothelial growth factor signaling pathway (ISO)

References

References - curated


1.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Pipeline to import Pathway Interaction Database annotations from NCI into RGD
3.	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:11786382	PMID:15919073	PMID:16971391	PMID:19223532	PMID:20585392	PMID:20624904	PMID:23528453	PMID:24645804

Genomics

Comparative Map Data

Shb
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	5	59,678,066 - 59,785,443 (-)	NCBI	mRatBN7.2
mRatBN7.2 Ensembl	5	59,678,216 - 59,785,538 (-)	Ensembl
Rnor_6.0	5	60,970,650 - 61,077,881 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	60,971,257 - 61,077,627 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	65,479,290 - 65,587,205 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	61,983,643 - 62,090,620 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
Celera	5	58,246,193 - 58,353,269 (-)	NCBI		Celera
Cytogenetic Map	5	q22	NCBI

SHB
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	9	37,915,898 - 38,069,227 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	9	37,915,898 - 38,069,227 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	9	37,915,895 - 38,069,224 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	37,905,895 - 38,059,210 (-)	NCBI	NCBI36		hg18	NCBI36
Build 34	9	37,909,613 - 38,059,208	NCBI
Celera	9	37,849,067 - 38,002,380 (-)	NCBI
Cytogenetic Map	9	p13.1	NCBI
HuRef	9	37,868,289 - 38,021,594 (-)	NCBI		HuRef
CHM1_1	9	37,917,509 - 38,070,825 (-)	NCBI		CHM1_1

Shb
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	45,423,276 - 45,530,828 (-)	NCBI	GRCm39		mm39
GRCm39 Ensembl	4	45,423,278 - 45,532,470 (-)	Ensembl
GRCm38	4	45,423,276 - 45,530,828 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	45,423,278 - 45,532,470 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	45,436,148 - 45,543,700 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	4	45,444,376 - 45,551,862 (-)	NCBI			mm8
MGSCv36	4	44,263,381 - 44,370,910 (-)	NCBI			mm8
Celera	4	45,444,918 - 45,556,568 (-)	NCBI		Celera
Cytogenetic Map	4	B1	NCBI

Shb
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955419	28,423,354 - 28,555,948 (+)	NCBI	ChiLan1.0	ChiLan1.0

SHB
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	9	38,694,980 - 38,843,827 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
Mhudiblu_PPA_v0	9	37,768,566 - 37,921,897 (-)	NCBI	Mhudiblu_PPA_v0		panPan3

SHB
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	11	54,189,580 - 54,329,004 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	11	54,189,843 - 54,329,325 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	11	52,615,325 - 52,754,488 (-)	NCBI
ROS_Cfam_1.0	11	55,298,243 - 55,437,485 (-)	NCBI
UMICH_Zoey_3.1	11	53,796,294 - 53,935,436 (-)	NCBI
UNSW_CanFamBas_1.0	11	53,826,088 - 53,965,258 (-)	NCBI
UU_Cfam_GSD_1.0	11	54,522,809 - 54,661,888 (-)	NCBI

Shb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	169,150,521 - 169,284,871 (-)	NCBI
SpeTri2.0	NW_004936524	5,698,101 - 5,832,801 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SHB
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	1	238,680,804 - 238,826,424 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	266,638,474 - 266,670,709 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SHB
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	12	42,520,803 - 42,669,892 (+)	NCBI	ChlSab1.1		chlSab2
Vero_WHO_p1.0	NW_023666038	39,581,717 - 39,730,643 (+)	NCBI	Vero_WHO_p1.0

Shb
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624825	3,846,604 - 3,972,780 (+)	NCBI	HetGla_female_1.0		hetGla2

Position Markers

D5Mgh10

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	59,793,399 - 59,793,528 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	61,086,525 - 61,086,653	NCBI	Rnor6.0
Rnor_5.0	5	65,595,163 - 65,595,291	UniSTS	Rnor5.0
RGSC_v3.4	5	62,098,647 - 62,098,775	UniSTS	RGSC3.4
RGSC_v3.4	5	62,098,646 - 62,098,775	RGD	RGSC3.4
RGSC_v3.1	5	62,098,825 - 62,098,954	RGD
Celera	5	58,361,489 - 58,361,617	UniSTS
SHRSP x BN Map	5	37.0299	RGD
SHRSP x BN Map	5	37.0299	UniSTS
Cytogenetic Map	5	q22	UniSTS

RH131997

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	59,905,869 - 59,906,064 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	61,225,560 - 61,225,754	NCBI	Rnor6.0
Rnor_5.0	5	65,729,011 - 65,729,205	UniSTS	Rnor5.0
RGSC_v3.4	5	62,153,496 - 62,153,690	UniSTS	RGSC3.4
Celera	5	58,471,648 - 58,471,842	UniSTS
RH 3.4 Map	5	378.2	UniSTS
Cytogenetic Map	5	q22	UniSTS

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1598807	Glom12	Glomerulus QTL 12	2.7		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	5	33215665	78215665	Rat
70189	Mcs5	Mammary carcinoma susceptibility QTL 5	10.51		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	55805606	132207589	Rat
70212	Niddm25	Non-insulin dependent diabetes mellitus QTL 25	3.54		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	5	1	131345958	Rat
2303574	Gluco42	Glucose level QTL 42	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	5	53496719	98496719	Rat
1331756	Rf34	Renal function QTL 34	4.16275		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	5	1	90450412	Rat
1331771	Rf35	Renal function QTL 35	4.36965		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	5	729470	86724018	Rat
1331773	Scl26	Serum cholesterol level QTL 26	3.065		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	43726656	86724018	Rat
1298067	Scl15	Serum cholesterol level QTL 15	4.8	0.001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	33215665	78215665	Rat
1331801	Rf33	Renal function QTL 33	4.149		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	5	43726656	129132602	Rat
1300115	Hrtrt7	Heart rate QTL 7	2.76		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	5	47869062	90099692	Rat
1302786	Kidm8	Kidney mass QTL 8	28.15		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	5	33215665	78215665	Rat
1641912	Alcrsp18	Alcohol response QTL 18			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	5	35189153	141643988	Rat
1641922	Alcrsp8	Alcohol response QTL 8			alcohol metabolism trait (VT:0015089)	blood ethanol level (CMO:0000535)	5	35189153	68564008	Rat
1598868	Mcs12	Mammary carcinoma susceptibility QTL 12		0.0001	mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	58973449	60051321	Rat
634305	Mamtr1	Mammary tumor resistance QTL 1		0.0001	mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	12789751	113558310	Rat
1358353	Srcrtb2	Stress Responsive Cort Basal QTL 2	3.48	0.003	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	5	18873947	74251464	Rat
1576312	Emca8	Estrogen-induced mammary cancer QTL 8	4.1		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	50328551	141643988	Rat
1576314	Eutr1	Estrogen induced uterine response QTL 1			uterus integrity trait (VT:0010575)	pyometritis severity score (CMO:0002009)	5	2138965	166875058	Rat
1576317	Eutr2	Estrogen induced uterine response QTL 2		0.01	uterus integrity trait (VT:0010575)	pyometritis severity score (CMO:0002009)	5	34730116	104251008	Rat
1600358	Mamtr5	Mammary tumor resistance QTL 5			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	18873947	63873947	Rat
1578766	Tcas11	Tongue tumor susceptibility QTL 11	4.12		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	5	46711509	161317411	Rat
1578767	Stresp17	Stress response QTL 17	4.3	0.01	blood aldosterone amount (VT:0005346)	plasma aldosterone level (CMO:0000551)	5	27955440	72955440	Rat
1578776	Stresp18	Stress response QTL 18	2.9		thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	5	27955440	72955440	Rat
2316959	Gluco59	Glucose level QTL 59	4.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	5	34944474	113558310	Rat
1549845	Scl44	Serum cholesterol level QTL 44	6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	40128307	148607290	Rat
2290448	Scl54	Serum cholesterol level QTL 54	2.93		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	31663789	131345958	Rat
2303615	Vencon7	Ventilatory control QTL 7		0.001	respiration trait (VT:0001943)	respiration rate (CMO:0000289)	5	50983895	95983895	Rat
1358895	Bp254	Blood pressure QTL 254	3.6	0.0003	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	5	58829236	128034027	Rat
61359	Eaex	Experimental allergic encephalomyelitis QTL x	3		nervous system integrity trait (VT:0010566)	post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)	5	55715622	100715622	Rat
6903292	Stl28	Serum triglyceride level QTL 28	2.6	0.0073	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	5	28515489	73515489	Rat
6903306	Scl35	Serum cholesterol QTL 35	2.6	0.0073	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	28515489	73515489	Rat
9589025	Epfw7	Epididymal fat weight QTL 7	20.66	0.001	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	5	49463600	94463600	Rat
8552954	Pigfal14	Plasma insulin-like growth factor 1 level QTL 14	9		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	21226744	66226744	Rat
7411561	Bw134	Body weight QTL 134	24	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	49463600	94463600	Rat
8662454	Vetf3	Vascular elastic tissue fragility QTL 3	27.4		artery integrity trait (VT:0010639)	number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)	5	2282226	69540447	Rat
7394712	Emca13	Estrogen-induced mammary cancer QTL 13			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	9823266	99753708	Rat

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	199
Count of miRNA genes:	149
Interacting mature miRNAs:	165
Transcripts:	ENSRNOT00000015338, ENSRNOT00000067955
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	40	30	26		26			59	35	33	11
Low		3	27	15	19	15	8	11	15		8		8
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_002726522	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006238148	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC136163	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000161	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000015338 ⟹ ENSRNOP00000015338

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	59,678,216 - 59,785,538 (-)	Ensembl
Rnor_6.0 Ensembl	5	60,971,257 - 61,077,627 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000116607 ⟹ ENSRNOP00000095708

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	59,684,479 - 59,785,538 (-)	Ensembl

RefSeq Acc Id:

XM_006238148 ⟹ XP_006238210

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	5	59,678,066 - 59,785,443 (-)	NCBI
Rnor_6.0	5	60,970,650 - 61,077,881 (-)	NCBI
Rnor_5.0	5	65,479,290 - 65,587,205 (-)	NCBI

Sequence:

show sequence

GACTCGTCTGTGAGGGGCGCGAGATCCGAAGCTCGGCCGGCGCGCAGCAGGGGCGGAGGGCTGT
GCAACAGCGGCCAGAGCCGGGCGGCGGCCGGCAGGAGGCGGCGGCTGCGAGAACTTGAACTTGG
CGACCGGTGCCCCGCACGCCCCCCACCGGGGCAGAGGCGCTGCGGGACTGGGCGGCAGTGTTGT
CCCCCGAATGGCCGCGGCGGCGGACGGGGCTCGCGCGCCGCGGCCCTAGGCGGCCCTTCGCCAT
GGCCAAGTGGCTGAACAAGTACTTCAGCTTAGGCAACAGCAAGACCAAGAGTCCACCGCAGCCG
CCGAGGCCGGACTACCGCGAGCAGCGGCGCCGGGGTGAGCGGCGCGAGCAGCCCCCGCAGGCCG
TGCCGCAGGCCTGCTCTGCGTCCTCGGCGTCCTGTGGGTCGGCCGCCGCCTGCTTCTCCGCCTC
GTCGGGCTCTTTGCCCGACGACAGCGGCAGCACGAGTGACCTCATCCGCGCCTACCGCGCGCAG
AAGGAGCGCGACTTCGAGGACCCGTACAACGGGCCGGGCTCGTCGCTGCGCAAACTGCGCGCCA
TGTGCCGCCTGGACTACTGCGGCGGCGGCGGGGACCCCGGCGGGGGCCAGCGCGCCTTCACGGC
GGCGGCAGGCGCTGCGGGCTGCTGCTGTGCGGCGGCGGGAGCGGGCGCCGCCGCGTCCTCATCC
TCATCATCCGGCTCCCCGCACCTCTACCGGAGCAGCAGCGAGCGGCGGCCGGCCACGCCGGCGG
AGGTGCGCTACATCTCCCCTAAGCACCGACTCATCAAAGTGGAGAGCGCGGGCGCTGCGGGGGA
CCCTCCGGGAGGCGTGTGCTCTGGCGGCCGCACCTGGAGCCCGACGACCTGCGGAGGCAAAAAA
TTGCTCAACAAGTGCGCCGCCGAGGAGACCGGAGCTGGTCAGAAAGACAAGGTGACCATAGCAG
ATGACTACTCTGATCCCTTTGATGCCAAGAACGACCTCAAGAGCAAAGCAGGAAAGGGTGAGAG
CGCTGGCTACATGGAGCCCTACGAAGCCCAAAGGATCATGACAGAATTCCAGAGGCAAGAGAGC
GTCCGGTCACAACACAAAGGCATCCAGTTGTATGACACCCCGTATGAGCCGGAAGGCCAGAGCG
TGGACTCAGACTCAGAGAGCACTGTGAGCCTTCGGCTTCGGGAGAGCAAGCTACCCCAGGACGA
CGACAGGCCTGCCGACGAGTACGACCAGCCGTGGGAATGGAACCGGGTCACCATCCCCGCCCTG
GCAGCCCAGTTCAATGGCAACGAGAAACGGCAGTCCTCCCCGTCGCCTTCTCGAGACCGACGGC
GTCAGCTCCGTGCCCCGGGAGGAGGCTTCAAGCCCATCAAACACGGCAGCCCTGAGTTCTGTGG
GATTCTGGGAGAGAGAGTGGATCCCACCATCCCACTGGAGAAACAAATATGGTATCACGGAGCC
ATCAGCAGAAGTGATGCCGAGAACCTTCTGCGACTCTGTAAGGAGTGCAGCTACCTTGTCCGGA
ACAGCCAGACCAGCAAACACGACTACTCCCTCTCCCTGAAGAGCAACCAGGGCTTCATGCACAT
GAAACTGGCCAAGACCAAAGACAAGTATGTTCTGGGTCAGAACAGCCCCCCTTTCGACAGTGTC
CCGGAAGTCATCCACTACTACACCACCAGGAAGCTACCCATCAAGGGGGCCGAGCACTTGTCCC
TCCTCTACCCAGTGGCTGTGCGGACTCTGTGAAAAGACCAGCCTCACCCTGCTCTGTGACCAAC
CACCGACCAGCCCTCTGTGCTGCCAGCCGTGTCCAGTGTGTGTCGTGTGTATGGTACAAGCACA
CCACTGCATGTCTTAGGATGCTGTCGCCACTTACAGGGTTGGAGAAGGCCTGGATGAAGGGGGG
CAGCCTGCTGCCACACCACCCCAGCCCCTACCCCATCCCCTCTGTGAATTAAAGTATTTGCAAT
CCAAAGAGATGCCTTCCAGGGTGAACAAAGGTGGAGCTGCTCCAGAGGTGGGCGGGGCCCTGCG
GTGGGTGGGGCGGAGCCCTGGCCTGCATCTCTCTGTTCTCCAGTTGTCAGGAACTCACCTGTGT
ATGGGCAAGGTTTTCCCATTGGTGCTGGGAGCCCAGGAGGCCCTGGGAGCCACCCTCTCTGGTC
TATGTCTGTGTTACTGGGTGTGCATATTGAGTGTACACAAGAGACCATGTCCTAAGCCGGAGTA
AGCCCCCATCTACTTTTAGATGTTCACTCTGTAATCGTTAGATGTCAAGGAACCATTGTGCAGA
CAAAGAGGGCGCAATTATTTATGGATATGATAGGGTGTGTAAATAAAATAGTCATTTAATATA

hide sequence

Protein Sequences


Protein RefSeqs	XP_006238210	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

XP_006238210 ⟸ XM_006238148

- UniProtKB:

D3ZN31 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAKWLNKYFSLGNSKTKSPPQPPRPDYREQRRRGERREQPPQAVPQACSASSASCGSAAACFSA
SSGSLPDDSGSTSDLIRAYRAQKERDFEDPYNGPGSSLRKLRAMCRLDYCGGGGDPGGGQRAFT
AAAGAAGCCCAAAGAGAAASSSSSSGSPHLYRSSSERRPATPAEVRYISPKHRLIKVESAGAAG
DPPGGVCSGGRTWSPTTCGGKKLLNKCAAEETGAGQKDKVTIADDYSDPFDAKNDLKSKAGKGE
SAGYMEPYEAQRIMTEFQRQESVRSQHKGIQLYDTPYEPEGQSVDSDSESTVSLRLRESKLPQD
DDRPADEYDQPWEWNRVTIPALAAQFNGNEKRQSSPSPSRDRRRQLRAPGGGFKPIKHGSPEFC
GILGERVDPTIPLEKQIWYHGAISRSDAENLLRLCKECSYLVRNSQTSKHDYSLSLKSNQGFMH
MKLAKTKDKYVLGQNSPPFDSVPEVIHYYTTRKLPIKGAEHLSLLYPVAVRTL

hide sequence

RefSeq Acc Id:

ENSRNOP00000015338 ⟸ ENSRNOT00000015338

RefSeq Acc Id:

ENSRNOP00000095708 ⟸ ENSRNOT00000116607

Protein Domains

SH2

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZN31-F1-model_v2	AlphaFold	D3ZN31	1-501	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Strain Variation

Strain Sequence Variants (MRatBN7.2)

ACI/EurMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

ACI/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BN-Lx/CubMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BN/NHsdMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BN/NHsdMcwi (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BN/SsN (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BUF/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BXH2/CubMcwi (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BXH3/CubMcwi (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

DA/OlaHsd (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Envigo
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

F344/DuCrl (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

F344/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

F344/NCrl (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

F344/Stm (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

FHH/EurMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

FXLE16/Stm (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

FXLE18/Stm (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

GK/FarMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB10/IpcvMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB2/IpcvMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB20/IpcvMcwi (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB31/IpcvMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB4/IpcvMcwi (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LE/Stm (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEW/Crl (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF10A/StmMcwi (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF11/Stm (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF1A/Stm (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF1C/Stm (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF2B/Stm (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF3/Stm (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF4/Stm (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LH/MavRrrcAek (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Kwitek
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LL/MavRrrcAek (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Kwitek
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LN/MavRrrcAek (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Kwitek
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

M520/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

M520/NRrrcMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

MR/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

MWF/Hsd (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

PVG/Seac (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

SHR/OlalpcvMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

SHRSP/A3NCrl (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

SR/JrHsd (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Envigo
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

SS/JrHsdMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

WAG/RijCrl (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

WKY/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

WKY/NCrl (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

WN/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1565350	AgrOrtholog
BioCyc Gene	G2FUF-41440	BioCyc
Ensembl Genes	ENSRNOG00000011503	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000015338	ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000015338	ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH	3.30.505.10	UniProtKB/TrEMBL
InterPro	SH2	UniProtKB/TrEMBL
	SH2_dom_sf	UniProtKB/TrEMBL
	SHB	UniProtKB/TrEMBL
	SHB_SH2	UniProtKB/TrEMBL
KEGG Report	rno:362513	UniProtKB/TrEMBL
NCBI Gene	362513	ENTREZGENE
PANTHER	PTHR15127:SF31	UniProtKB/TrEMBL
Pfam	SH2	UniProtKB/TrEMBL
PhenoGen	Shb	PhenoGen
PRINTS	SH2DOMAIN	UniProtKB/TrEMBL
PROSITE	SH2	UniProtKB/TrEMBL
SMART	SH2	UniProtKB/TrEMBL
Superfamily-SCOP	SSF55550	UniProtKB/TrEMBL
UniProt	D3ZN31	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-04-20	Shb	SH2 domain containing adaptor protein B	Shb	Src homology 2 domain containing adaptor protein B	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2012-10-12	Shb	Src homology 2 domain containing adaptor protein B	RGD1565350	similar to Shb protein	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	RGD1565350	similar to Shb protein	RGD1565350_predicted	similar to Shb protein (predicted)	'predicted' is removed	2292626	APPROVED
2006-03-07	RGD1565350_predicted	similar to Shb protein (predicted)	LOC362513	similar to Shb protein	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC362513	similar to Shb protein			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Annotations - PID (archival)