Akap2 (A-kinase anchoring protein 2) - Rat Genome Database

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Pathways
Gene: Akap2 (A-kinase anchoring protein 2) Rattus norvegicus
Analyze
Symbol: Akap2
Name: A-kinase anchoring protein 2
RGD ID: 1305135
Description: Enables protein domain specific binding activity. Predicted to be involved in regulation of cell shape. Predicted to act upstream of or within actin filament organization; protein localization; and transmembrane receptor protein serine/threonine kinase signaling pathway. Part of protein-containing complex. Orthologous to human PALM2AKAP2 (PALM2 and AKAP2 fusion); PARTICIPATES IN protein kinase A (PKA) signaling pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: A kinase (PRKA) anchor protein 2; A-kinase anchor protein 2; AKAP-2; LOC298024
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2572,536,986 - 72,648,524 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl572,181,718 - 72,648,524 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx574,496,206 - 74,539,933 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0576,317,831 - 76,361,558 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0576,289,961 - 76,333,686 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0574,874,245 - 74,985,789 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl574,874,306 - 74,982,401 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0578,666,031 - 79,127,060 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4575,814,965 - 75,855,492 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1575,820,077 - 75,860,603 (+)NCBI
Celera571,452,762 - 71,496,505 (+)NCBICelera
Cytogenetic Map5q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-butoxyethanol  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
8-Br-cAMP  (ISO)
acrolein  (ISO)
acrylamide  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
amphetamine  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
Brodifacoum  (EXP)
bucladesine  (ISO)
C60 fullerene  (EXP)
caffeine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chloroprene  (EXP)
ciglitazone  (ISO)
cisplatin  (ISO)
clozapine  (ISO)
cobalt dichloride  (ISO)
coumarin  (ISO)
crocidolite asbestos  (ISO)
Cuprizon  (ISO)
cyclophosphamide  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
diallyl trisulfide  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
dorsomorphin  (ISO)
elemental selenium  (ISO)
endosulfan  (EXP)
enzyme inhibitor  (ISO)
fenvalerate  (EXP)
fipronil  (EXP)
flutamide  (EXP)
folic acid  (ISO)
fulvestrant  (ISO)
gentamycin  (EXP)
glycidyl methacrylate  (ISO)
indometacin  (ISO)
lead(0)  (ISO)
leflunomide  (ISO)
lipopolysaccharide  (ISO)
medroxyprogesterone acetate  (ISO)
methapyrilene  (ISO)
methimazole  (EXP)
methylmercury chloride  (ISO)
methylseleninic acid  (ISO)
ozone  (ISO)
paracetamol  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
rimonabant  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (ISO)
Soman  (EXP)
tamibarotene  (ISO)
testosterone enanthate  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
triphenyl phosphate  (EXP)
triptonide  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vitamin E  (ISO)
vorinostat  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. A-kinase anchoring proteins: from protein complexes to physiology and disease. Carnegie GK, etal., IUBMB Life. 2009 Apr;61(4):394-406.
2. A dynamic mechanism for AKAP binding to RII isoforms of cAMP-dependent protein kinase. Kinderman FS, etal., Mol Cell. 2006 Nov 3;24(3):397-408.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Localized effects of cAMP mediated by distinct routes of protein kinase A. Tasken K and Aandahl EM, Physiol Rev. 2004 Jan;84(1):137-67.
Additional References at PubMed
PMID:9497389   PMID:12477932   PMID:21873635  


Genomics

Comparative Map Data
Akap2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2572,536,986 - 72,648,524 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl572,181,718 - 72,648,524 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx574,496,206 - 74,539,933 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0576,317,831 - 76,361,558 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0576,289,961 - 76,333,686 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0574,874,245 - 74,985,789 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl574,874,306 - 74,982,401 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0578,666,031 - 79,127,060 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4575,814,965 - 75,855,492 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1575,820,077 - 75,860,603 (+)NCBI
Celera571,452,762 - 71,496,505 (+)NCBICelera
Cytogenetic Map5q24NCBI
PALM2AKAP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389109,640,787 - 110,172,512 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9109,498,325 - 110,172,512 (+)EnsemblGRCh38hg38GRCh38
GRCh379112,403,067 - 112,934,792 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369111,582,398 - 111,974,613 (+)NCBINCBI36Build 36hg18NCBI36
Build 349109,622,273 - 109,785,306NCBI
Celera983,044,274 - 83,436,417 (+)NCBICelera
Cytogenetic Map9q31.3NCBI
HuRef982,144,738 - 82,536,888 (+)NCBIHuRef
CHM1_19112,689,212 - 113,081,245 (+)NCBICHM1_1
T2T-CHM13v2.09121,810,203 - 122,342,040 (+)NCBIT2T-CHM13v2.0
Pakap
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39457,434,475 - 57,896,984 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl457,568,179 - 57,896,982 (+)EnsemblGRCm39 Ensembl
GRCm39 Ensembl457,717,657 - 57,896,984 (+)EnsemblGRCm39 Ensembl
GRCm39 Ensembl457,434,247 - 57,712,016 (+)EnsemblGRCm39 Ensembl
GRCm38457,434,475 - 57,896,984 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl457,568,179 - 57,896,982 (+)EnsemblGRCm38mm10GRCm38
GRCm38.p6 Ensembl457,717,657 - 57,896,984 (+)EnsemblGRCm38mm10GRCm38
GRCm38.p6 Ensembl457,434,247 - 57,712,016 (+)EnsemblGRCm38mm10GRCm38
MGSCv37457,581,154 - 57,730,017 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36457,662,302 - 57,805,856 (+)NCBIMGSCv36mm8
Celera457,480,009 - 57,628,214 (+)NCBICelera
Cytogenetic Map4B3NCBI
cM Map431.66NCBI
PALM2AKAP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1929,236,065 - 29,769,190 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0980,794,036 - 81,328,270 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19109,104,006 - 109,494,631 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9109,413,921 - 109,494,631 (+)Ensemblpanpan1.1panPan2
PALM2AKAP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11164,841,405 - 65,178,204 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1164,842,167 - 65,175,262 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1163,241,589 - 63,578,592 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01165,975,096 - 66,305,415 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1165,834,080 - 66,304,619 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11164,495,896 - 64,825,223 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01164,515,888 - 64,846,733 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01165,206,125 - 65,537,222 (+)NCBIUU_Cfam_GSD_1.0
Palm2akap2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947179,948,400 - 180,406,419 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365592,860,147 - 2,997,627 (-)EnsemblSpeTri2.0
SpeTri2.0NW_0049365592,860,595 - 3,194,846 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PALM2AKAP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1250,680,942 - 251,190,244 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11250,984,658 - 251,190,244 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11250,824,055 - 250,968,545 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21281,712,174 - 281,730,889 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Sscrofa10.21281,586,884 - 281,587,188 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PALM2AKAP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11229,371,705 - 29,908,100 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1229,371,209 - 29,604,909 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603512,809,675 - 13,393,649 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Akap2
780 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:156
Count of miRNA genes:116
Interacting mature miRNAs:135
Transcripts:ENSRNOT00000015576
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)5190450412Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51131345958Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)572947086724018Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
7394712Emca13Estrogen-induced mammary cancer QTL 13mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)5982326699753708Rat
634305Mamtr1Mammary tumor resistance QTL 10.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)512789751113558310Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)51887394774251464Rat
1578767Stresp17Stress response QTL 174.30.01blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)52795544072955440Rat
1578776Stresp18Stress response QTL 182.9thymus mass (VT:0004954)thymus wet weight (CMO:0000855)52795544072955440Rat
6903292Stl28Serum triglyceride level QTL 282.60.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)52851548973515489Rat
6903306Scl35Serum cholesterol QTL 352.60.0073blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)52851548973515489Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)531663789131345958Rat
1598807Glom12Glomerulus QTL 122.7kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)53321566578215665Rat
1298067Scl15Serum cholesterol level QTL 154.80.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53321566578215665Rat
1302786Kidm8Kidney mass QTL 828.15kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)53321566578215665Rat
1576317Eutr2Estrogen induced uterine response QTL 20.01uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)534730116104251008Rat
2316959Gluco59Glucose level QTL 594.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)534944474113558310Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)535189153141643988Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
1331773Scl26Serum cholesterol level QTL 263.065blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)54372665686724018Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)543726656129132602Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
1300115Hrtrt7Heart rate QTL 72.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)54786906290099692Rat
9589025Epfw7Epididymal fat weight QTL 720.660.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)54946360094463600Rat
7411561Bw134Body weight QTL 134240.001body mass (VT:0001259)body weight gain (CMO:0000420)54946360094463600Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)550328551141643988Rat
2303615Vencon7Ventilatory control QTL 70.001respiration trait (VT:0001943)respiration rate (CMO:0000289)55098389595983895Rat
2303574Gluco42Glucose level QTL 422blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)55349671998496719Rat
61359EaexExperimental allergic encephalomyelitis QTL x3nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)555715622100715622Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555805606132207589Rat
1358895Bp254Blood pressure QTL 2543.60.0003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)558829236128034027Rat
61426Scl2Serum cholesterol level QTL 27.30.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)559793399143070159Rat
2316954Rf57Renal function QTL 570kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)55979352890450144Rat
2316957Pur21Proteinuria QTL 216.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)559793528113558156Rat
61386Bp49Blood pressure QTL 4916.6cerebrum integrity trait (VT:0010549)brain infarction volume (CMO:0001013)56029343498603051Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)560293434161481680Rat
2290005Mcs24Mammary carcinoma susceptibility QTL 24mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)564719390109719390Rat
2306971Anxrr21Anxiety related response QTL 219.47fear/anxiety-related behavior trait (VT:1000241)number of entries into a discrete space in an experimental apparatus (CMO:0000960)566174080124160948Rat
2312671Scl64Serum cholesterol level QTL 640.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)568984307104251008Rat
61380Edpm5Estrogen-dependent pituitary mass QTL 54.50.92pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)568984307104251008Rat
1357396Bw44Body weight QTL 444.19body mass (VT:0001259)body weight (CMO:0000012)568984307104251008Rat
1357402Bw46Body weight QTL 464.47body mass (VT:0001259)body mass index (BMI) (CMO:0000105)568984307104251008Rat
2302381Bw84Body weight QTL 844.47body mass (VT:0001259)body mass index (BMI) (CMO:0000105)568984307104251008Rat
1354598Srn6Serum renin concentration QTL 63.8blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)569540295151018848Rat

Markers in Region
RH141890  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2572,644,899 - 72,645,093 (+)MAPPERmRatBN7.2
Rnor_6.0574,982,165 - 74,982,358NCBIRnor6.0
Rnor_5.0579,123,437 - 79,123,630UniSTSRnor5.0
RGSC_v3.4575,855,258 - 75,855,451UniSTSRGSC3.4
Celera571,492,887 - 71,493,080UniSTS
RH 3.4 Map5494.7UniSTS
Cytogenetic Map5q24UniSTS
RH137540  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2572,637,014 - 72,637,158 (+)MAPPERmRatBN7.2
Rnor_6.0574,974,282 - 74,974,425NCBIRnor6.0
Rnor_5.0579,115,517 - 79,115,660UniSTSRnor5.0
RGSC_v3.4575,847,373 - 75,847,516UniSTSRGSC3.4
Celera571,484,984 - 71,485,127UniSTS
Cytogenetic Map5q24UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 43 26 10 19 10 8 10 74 35 41 11 8
Low 1 31 31 31 1
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000015576   ⟹   ENSRNOP00000015576
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl572,593,613 - 72,623,047 (+)Ensembl
Rnor_6.0 Ensembl574,941,802 - 74,982,401 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000030913   ⟹   ENSRNOP00000030796
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl572,380,680 - 72,449,473 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000076918   ⟹   ENSRNOP00000067989
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl574,874,306 - 74,954,873 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000097436   ⟹   ENSRNOP00000087137
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl572,604,829 - 72,648,524 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000097969   ⟹   ENSRNOP00000087434
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl572,313,560 - 72,648,522 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000098662   ⟹   ENSRNOP00000089455
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl572,313,560 - 72,648,524 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000106097   ⟹   ENSRNOP00000077701
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl572,181,718 - 72,646,031 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000114485   ⟹   ENSRNOP00000090369
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl572,312,916 - 72,646,031 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000117085   ⟹   ENSRNOP00000092250
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl572,574,582 - 72,648,522 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000117632   ⟹   ENSRNOP00000078673
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl572,313,560 - 72,648,522 (+)Ensembl
RefSeq Acc Id: NM_001011974   ⟹   NP_001011974
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2572,604,829 - 72,648,524 (+)NCBI
Rnor_6.0574,942,091 - 74,985,789 (+)NCBI
Rnor_5.0578,666,031 - 79,127,060 (+)NCBI
RGSC_v3.4575,814,965 - 75,855,492 (+)RGD
Celera571,452,762 - 71,496,505 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001309260   ⟹   NP_001296189
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2572,604,829 - 72,648,524 (+)NCBI
Rnor_6.0574,942,091 - 74,985,789 (+)NCBI
Celera571,452,762 - 71,496,505 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006238185   ⟹   XP_006238247
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2572,604,746 - 72,648,524 (+)NCBI
Rnor_6.0574,941,558 - 74,985,789 (+)NCBI
Rnor_5.0578,666,031 - 79,127,060 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006238186   ⟹   XP_006238248
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2572,536,986 - 72,648,524 (+)NCBI
Rnor_6.0574,874,245 - 74,985,789 (+)NCBI
Rnor_5.0578,666,031 - 79,127,060 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039109444   ⟹   XP_038965372
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2572,604,746 - 72,648,524 (+)NCBI
RefSeq Acc Id: XM_039109445   ⟹   XP_038965373
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2572,604,545 - 72,648,524 (+)NCBI
RefSeq Acc Id: XM_039109446   ⟹   XP_038965374
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2572,604,746 - 72,648,524 (+)NCBI
RefSeq Acc Id: NP_001011974   ⟸   NM_001011974
- Peptide Label: isoform 2
- UniProtKB: Q5U301 (UniProtKB/Swiss-Prot),   F1LPQ9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006238248   ⟸   XM_006238186
- Peptide Label: isoform X1
- UniProtKB: Q5U301 (UniProtKB/Swiss-Prot),   A0A8I6A5A3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006238247   ⟸   XM_006238185
- Peptide Label: isoform X1
- UniProtKB: Q5U301 (UniProtKB/Swiss-Prot),   A0A8I6A5A3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001296189   ⟸   NM_001309260
- Peptide Label: isoform 1
- UniProtKB: Q5U301 (UniProtKB/Swiss-Prot),   A0A8I6A5A3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000067989   ⟸   ENSRNOT00000076918
RefSeq Acc Id: ENSRNOP00000015576   ⟸   ENSRNOT00000015576
RefSeq Acc Id: XP_038965373   ⟸   XM_039109445
- Peptide Label: isoform X3
- UniProtKB: F1LPQ9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038965372   ⟸   XM_039109444
- Peptide Label: isoform X2
- UniProtKB: Q5U301 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038965374   ⟸   XM_039109446
- Peptide Label: isoform X3
- UniProtKB: F1LPQ9 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000089455   ⟸   ENSRNOT00000098662
RefSeq Acc Id: ENSRNOP00000087434   ⟸   ENSRNOT00000097969
RefSeq Acc Id: ENSRNOP00000087137   ⟸   ENSRNOT00000097436
RefSeq Acc Id: ENSRNOP00000092250   ⟸   ENSRNOT00000117085
RefSeq Acc Id: ENSRNOP00000077701   ⟸   ENSRNOT00000106097
RefSeq Acc Id: ENSRNOP00000030796   ⟸   ENSRNOT00000030913
RefSeq Acc Id: ENSRNOP00000090369   ⟸   ENSRNOT00000114485
RefSeq Acc Id: ENSRNOP00000078673   ⟸   ENSRNOT00000117632
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5U301-F1-model_v2 AlphaFold Q5U301 1-870 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305135 AgrOrtholog
BioCyc Gene G2FUF-41196 BioCyc
Ensembl Genes ENSRNOG00000011504 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000015576.7 UniProtKB/TrEMBL
  ENSRNOP00000077701.1 UniProtKB/TrEMBL
  ENSRNOP00000078673.1 UniProtKB/TrEMBL
  ENSRNOP00000087137 ENTREZGENE
  ENSRNOP00000087137.1 UniProtKB/TrEMBL
  ENSRNOP00000087434.1 UniProtKB/TrEMBL
  ENSRNOP00000089455.1 UniProtKB/TrEMBL
  ENSRNOP00000090369.1 UniProtKB/TrEMBL
  ENSRNOP00000092250 ENTREZGENE
  ENSRNOP00000092250.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000015576.7 UniProtKB/TrEMBL
  ENSRNOT00000097436 ENTREZGENE
  ENSRNOT00000097436.1 UniProtKB/TrEMBL
  ENSRNOT00000097969.1 UniProtKB/TrEMBL
  ENSRNOT00000098662.1 UniProtKB/TrEMBL
  ENSRNOT00000106097.1 UniProtKB/TrEMBL
  ENSRNOT00000114485.1 UniProtKB/TrEMBL
  ENSRNOT00000117085 ENTREZGENE
  ENSRNOT00000117085.1 UniProtKB/TrEMBL
  ENSRNOT00000117632.1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7108964 IMAGE-MGC_LOAD
InterPro AKAP2_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Paralemmin UniProtKB/TrEMBL
KEGG Report rno:298024 UniProtKB/TrEMBL
MGC_CLONE MGC:93771 IMAGE-MGC_LOAD
NCBI Gene 298024 ENTREZGENE
PANTHER PALM2 AND AKAP2 FUSION-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PARALEMMIN-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam AKAP2_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Paralemmin UniProtKB/TrEMBL
PhenoGen Akap2 PhenoGen
UniProt A0A8I5Y1X4_RAT UniProtKB/TrEMBL
  A0A8I6A5A3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A782_RAT UniProtKB/TrEMBL
  A0A8I6AAB5_RAT UniProtKB/TrEMBL
  A0A8I6ACD4_RAT UniProtKB/TrEMBL
  A0A8I6ADB4_RAT UniProtKB/TrEMBL
  A0A8I6G255_RAT UniProtKB/TrEMBL
  AKAP2_RAT UniProtKB/Swiss-Prot
  F1LPQ9 ENTREZGENE, UniProtKB/TrEMBL
  Q5U301 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-25 Akap2  A-kinase anchoring protein 2  Akap2  A kinase (PRKA) anchor protein 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Akap2  A kinase (PRKA) anchor protein 2  Akap2_predicted  A kinase (PRKA) anchor protein 2 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Akap2_predicted  A kinase (PRKA) anchor protein 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED