Tpm2 (tropomyosin 2) - Rat Genome Database

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Gene: Tpm2 (tropomyosin 2) Rattus norvegicus
Analyze
Symbol: Tpm2
Name: tropomyosin 2
RGD ID: 1559479
Description: Exhibits actin filament binding activity; protein heterodimerization activity; and protein homodimerization activity. Predicted to be involved in actin filament organization; muscle contraction; and regulation of ATPase activity. Localizes to actin cytoskeleton. Human ortholog(s) of this gene implicated in distal arthrogryposis type 1A and nemaline myopathy 4. Orthologous to human TPM2 (tropomyosin 2); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: beta-tropomyosin; MGC109519; similar to tropomyosin 1, embryonic fibroblast - rat; tropomyosin; tropomyosin 2, beta; tropomyosin beta chain; tropomyosin-2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2557,770,919 - 57,780,278 (-)NCBI
Rnor_6.0 Ensembl559,016,622 - 59,025,631 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0559,016,616 - 59,025,971 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0563,541,215 - 63,550,146 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4559,994,101 - 60,003,261 (-)NCBIRGSC3.4rn4RGSC3.4
Celera556,351,476 - 56,360,486 (-)NCBICelera
Cytogenetic Map5q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-azacytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
aristolochic acid  (ISO)
benzo[a]pyrene  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
cadmium dichloride  (EXP,ISO)
carbon nanotube  (ISO)
chloropicrin  (ISO)
cisplatin  (EXP,ISO)
clofibrate  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
DDT  (EXP)
decabromodiphenyl ether  (EXP)
dexamethasone  (ISO)
dextran sulfate  (ISO)
dibutyl phthalate  (EXP,ISO)
diethyl maleate  (EXP)
dioxygen  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
elemental selenium  (ISO)
entinostat  (ISO)
furan  (EXP)
graphene oxide  (ISO)
graphite  (ISO)
hyaluronic acid  (EXP)
hydralazine  (ISO)
hydrogen peroxide  (EXP)
mercury atom  (ISO)
mercury(0)  (ISO)
methimazole  (EXP)
oxaliplatin  (EXP)
paracetamol  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (EXP,ISO)
phenylephrine  (EXP)
PhIP  (EXP)
pirinixic acid  (EXP,ISO)
potassium dichromate  (ISO)
resveratrol  (EXP)
SB 431542  (ISO)
selenium atom  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (EXP)
sodium fluoride  (ISO)
Soman  (EXP)
spermine  (ISO)
sunitinib  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
valproic acid  (ISO)
vancomycin  (ISO)
vinclozolin  (EXP)
vitamin E  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
acebutolol pharmacodynamics pathway  (ISO)
adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway  (ISO)
amiodarone pharmacodynamics pathway  (ISO)
amlodipine pharmacodynamics pathway  (ISO)
atenolol pharmacodynamics pathway  (ISO)
betaxolol pharmacodynamics pathway  (ISO)
bisoprolol pharmacodynamics pathway  (ISO)
bupranolol drug pathway  (ISO)
bupranolol pharmacodynamics pathway  (ISO)
carvedilol pharmacodynamics pathway  (ISO)
dilated cardiomyopathy pathway  (IEA)
diltiazem pharmacodynamics pathway  (ISO)
disopyramide pharmacodynamics pathway  (ISO)
dobutamine pharmacodynamics pathway  (ISO)
esmolol pharmacodynamics pathway  (ISO)
flecainde pharmacodynamics pathway  (ISO)
fosphenytoin pharmacodynamics pathway  (ISO)
hypertrophic cardiomyopathy pathway  (IEA)
ibutilide pharmacodynamics pathway  (ISO)
isoprenaline pharmacodynamics pathway  (ISO)
isradipine pharmacodynamics pathway  (ISO)
levobunolol pharmacodynamics pathway  (ISO)
lidocaine pharmacodynamics pathway  (ISO)
metoprolol pharmacodynamics pathway  (ISO)
mexiletine pharmacodynamics pathway  (ISO)
nadolol pharmacodynamics pathway  (ISO)
nebivolol pharmacodynamics pathway  (ISO)
nifedipine pharmacodynamics pathway  (ISO)
nimodipine pharmacodynamics pathway  (ISO)
nisoldipine pharmacodynamics pathway  (ISO)
nitrendipine pharmacodynamics pathway  (ISO)
penbutolol pharmacodynamics pathway  (ISO)
phenytoin pharmacodynamics pathway  (ISO)
pindolol pharmacodynamics pathway  (ISO)
procainamide pharmacodynamics pathway  (ISO)
propranolol pharmacodynamics pathway  (ISO)
quinidine pharmacodynamics pathway  (ISO)
sotalol pharmacodynamics pathway  (ISO)
timolol pharmacodynamics pathway  (ISO)
verapamil pharmacodynamics pathway  (ISO)

References

Additional References at PubMed
PMID:2432392   PMID:3840484   PMID:8889548   PMID:12947022   PMID:17194691   PMID:19182904   PMID:25369766   PMID:29183317  


Genomics

Comparative Map Data
Tpm2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2557,770,919 - 57,780,278 (-)NCBI
Rnor_6.0 Ensembl559,016,622 - 59,025,631 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0559,016,616 - 59,025,971 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0563,541,215 - 63,550,146 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4559,994,101 - 60,003,261 (-)NCBIRGSC3.4rn4RGSC3.4
Celera556,351,476 - 56,360,486 (-)NCBICelera
Cytogenetic Map5q22NCBI
TPM2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl935,681,992 - 35,690,056 (-)EnsemblGRCh38hg38GRCh38
GRCh38935,681,993 - 35,690,056 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37935,681,990 - 35,690,053 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36935,671,990 - 35,680,053 (-)NCBINCBI36hg18NCBI36
Celera935,615,536 - 35,623,601 (-)NCBI
Cytogenetic Map9p13.3NCBI
HuRef935,637,598 - 35,645,663 (-)NCBIHuRef
CHM1_1935,681,818 - 35,689,882 (-)NCBICHM1_1
Tpm2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39443,513,726 - 43,523,583 (-)NCBIGRCm39mm39
GRCm39 Ensembl443,514,711 - 43,523,765 (-)Ensembl
GRCm38443,513,726 - 43,523,583 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl443,514,711 - 43,523,765 (-)EnsemblGRCm38mm10GRCm38
MGSCv37443,527,584 - 43,536,260 (-)NCBIGRCm37mm9NCBIm37
MGSCv36443,535,812 - 43,544,488 (-)NCBImm8
Celera443,548,571 - 43,557,214 (-)NCBICelera
Cytogenetic Map4A5NCBI
Tpm2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955472611,028 - 617,821 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955472611,079 - 617,823 (+)NCBIChiLan1.0ChiLan1.0
TPM2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1936,336,307 - 36,345,394 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl936,336,307 - 36,345,394 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0935,533,982 - 35,542,033 (-)NCBIMhudiblu_PPA_v0panPan3
TPM2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11152,212,372 - 52,219,947 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1152,212,401 - 52,219,923 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1150,779,956 - 50,787,531 (-)NCBI
ROS_Cfam_1.01153,277,326 - 53,284,901 (-)NCBI
UMICH_Zoey_3.11151,821,901 - 51,829,478 (-)NCBI
UNSW_CanFamBas_1.01151,805,386 - 51,812,960 (-)NCBI
UU_Cfam_GSD_1.01152,507,526 - 52,515,101 (-)NCBI
Tpm2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947167,132,139 - 167,140,168 (-)NCBI
SpeTri2.0NW_0049365243,679,719 - 3,687,828 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TPM2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1236,402,247 - 236,410,471 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11236,402,249 - 236,410,390 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21264,127,284 - 264,135,301 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap1q23-q27NCBI
TPM2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11244,912,250 - 44,920,615 (+)NCBI
ChlSab1.1 Ensembl1244,912,223 - 44,919,456 (+)Ensembl
Vero_WHO_p1.0NW_02366603842,015,821 - 42,025,459 (+)NCBI
Tpm2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248685,101,713 - 5,109,560 (+)NCBI

Position Markers
RH127874  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2557,771,041 - 57,771,396 (+)MAPPER
Rnor_6.0559,016,739 - 59,017,093NCBIRnor6.0
Rnor_5.0563,541,333 - 63,541,687UniSTSRnor5.0
RGSC_v3.4559,994,219 - 59,994,573UniSTSRGSC3.4
Celera556,351,594 - 56,351,948UniSTS
RH 3.4 Map5394.8UniSTS
Cytogenetic Map5q22UniSTS
BI277374  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2557,771,921 - 57,772,126 (+)MAPPER
Rnor_6.0559,017,619 - 59,017,823NCBIRnor6.0
Rnor_5.0563,542,213 - 63,542,417UniSTSRnor5.0
RGSC_v3.4559,995,099 - 59,995,303UniSTSRGSC3.4
Celera556,352,474 - 56,352,678UniSTS
RH 3.4 Map5394.8UniSTS
Cytogenetic Map5q22UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)5189432042Rat
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)5193273395Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51136640934Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)5152509878720537Rat
8662454Vetf3Vascular elastic tissue fragility QTL 327.4artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)5166658771552720Rat
7394712Emca13Estrogen-induced mammary cancer QTL 13mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)59514842103580403Rat
634305Mamtr1Mammary tumor resistance QTL 10.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)512651967117554267Rat
1600358Mamtr5Mammary tumor resistance QTL 5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)51884791363847913Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)51884791376608178Rat
8552954Pigfal14Plasma insulin-like growth factor 1 level QTL 149blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)52190436366904363Rat
1578767Stresp17Stress response QTL 174.30.01blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)52907889974078899Rat
1578776Stresp18Stress response QTL 182.9thymus mass (VT:0004954)thymus wet weight (CMO:0000855)52907889974078899Rat
6903292Stl28Serum triglyceride level QTL 282.60.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)52964166174641661Rat
6903306Scl35Serum cholesterol QTL 352.60.0073blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)52964166174641661Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)531926122136640934Rat
1298067Scl15Serum cholesterol level QTL 154.80.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53440240979402409Rat
1302786Kidm8Kidney mass QTL 828.15kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)53440240979402409Rat
1598807Glom12Glomerulus QTL 122.7kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)53440240979402409Rat
1576317Eutr2Estrogen induced uterine response QTL 20.01uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)535225432108092802Rat
2316959Gluco59Glucose level QTL 594.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)535661945117554267Rat
1641922Alcrsp8Alcohol response QTL 8alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)53578875670742105Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)535788756147487820Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540777918154732375Rat
1331773Scl26Serum cholesterol level QTL 263.065blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)54440427689432042Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)544404276134502294Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)547745646167946134Rat
1300115Hrtrt7Heart rate QTL 72.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)54872203893587756Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)551418671147487820Rat
9589025Epfw7Epididymal fat weight QTL 720.660.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)55180442696804426Rat
7411561Bw134Body weight QTL 134240.001body mass (VT:0001259)body weight gain (CMO:0000420)55180442696804426Rat
2303615Vencon7Ventilatory control QTL 70.001respiration trait (VT:0001943)respiration rate (CMO:0000289)55330956898309568Rat
2303574Gluco42Glucose level QTL 422blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)555903593100903593Rat
61359EaexExperimental allergic encephalomyelitis QTL x3nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)556902367101902367Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)556991667137729065Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:198
Count of miRNA genes:135
Interacting mature miRNAs:152
Transcripts:ENSRNOT00000022801, ENSRNOT00000049000
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 5 8 11 1 8
Medium 2 43 29 15 19 15 63 35 40 11
Low 28 26 26 11
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001024345 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001301235 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008763680 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008763681 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC121204 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC090009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CF110059 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473962 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CV796622 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ118075 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214586 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214609 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214618 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214635 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214647 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214711 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214760 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214816 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214823 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214840 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214899 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215047 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215066 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215076 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215143 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215150 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215210 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215302 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215335 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215502 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215545 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215676 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215735 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215736 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215883 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215904 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215916 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215920 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215926 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216071 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216112 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216187 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216228 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216294 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216422 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216477 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216483 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216571 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216617 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216760 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216806 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216828 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216972 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217324 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217401 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217430 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217483 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217661 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217946 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219788 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219821 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220438 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220606 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220675 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223760 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224841 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224873 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224893 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229470 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229835 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000161 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000022801   ⟹   ENSRNOP00000022801
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl559,017,575 - 59,025,631 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000049000   ⟹   ENSRNOP00000044473
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl559,016,622 - 59,025,631 (-)Ensembl
RefSeq Acc Id: NM_001024345   ⟹   NP_001019516
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2557,770,924 - 57,779,938 (-)NCBI
Rnor_6.0559,016,621 - 59,025,631 (-)NCBI
Rnor_5.0563,541,215 - 63,550,146 (-)NCBI
RGSC_v3.4559,994,101 - 60,003,261 (-)RGD
Celera556,351,476 - 56,360,486 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001301235   ⟹   NP_001288164
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2557,771,877 - 57,779,938 (-)NCBI
Rnor_6.0559,017,574 - 59,025,631 (-)NCBI
Celera556,352,429 - 56,360,486 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008763680   ⟹   XP_008761902
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2557,770,919 - 57,780,278 (-)NCBI
Rnor_6.0559,016,616 - 59,025,971 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008763681   ⟹   XP_008761903
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2557,771,877 - 57,780,278 (-)NCBI
Rnor_6.0559,017,574 - 59,025,971 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_001019516   ⟸   NM_001024345
- Peptide Label: isoform Tpm2.1sm/cy
- UniProtKB: P58775 (UniProtKB/Swiss-Prot),   Q5FVG5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008761902   ⟸   XM_008763680
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_008761903   ⟸   XM_008763681
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: NP_001288164   ⟸   NM_001301235
- Peptide Label: isoform Tpm2.2st
- UniProtKB: P58775 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000022801   ⟸   ENSRNOT00000022801
RefSeq Acc Id: ENSRNOP00000044473   ⟸   ENSRNOT00000049000

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693677
Promoter ID:EPDNEW_R4202
Type:initiation region
Name:Tpm2_1
Description:tropomyosin 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0559,025,568 - 59,025,628EPDNEW
RGD ID:6849480
Promoter ID:EP25019
Type:single initiation site
Name:RN_TPM1
Description:Tropomyosin-beta (skeletal muscle beta)
SO ACC ID:SO:0000170
Source:EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Notes:homology_group=Homology group 140; Mammalian tropomyosin beta
Experiment Methods:Nuclease protection; Primer extension
Regulation:skel (repressed by or weakly expressed in) m., smooth muscle, fibroblasts
Position:
Rat AssemblyChrPosition (strand)Source
RGSC_v3.4560,003,279 - 60,003,339EPD

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1559479 AgrOrtholog
Ensembl Genes ENSRNOG00000016731 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSRNOP00000022801 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000044473 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000022801 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000049000 ENTREZGENE, UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7324151 IMAGE-MGC_LOAD
InterPro Tropomyosin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:500450 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:109519 IMAGE-MGC_LOAD
NCBI Gene 500450 ENTREZGENE
Pfam Tropomyosin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Tpm2 PhenoGen
PRINTS TROPOMYOSIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE TROPOMYOSIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt P58775 ENTREZGENE
  Q5FVG5 ENTREZGENE, UniProtKB/TrEMBL
  TPM2_RAT UniProtKB/Swiss-Prot
UniProt Secondary P02560 UniProtKB/Swiss-Prot
  P06395 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-06-12 Tpm2  tropomyosin 2  Tpm2  tropomyosin 2, beta  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-10-22 Tpm2  tropomyosin 2, beta  Tpm2  tropomyosin 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-06 Tpm2  tropomyosin 2  MGC109519  similar to tropomyosin 1, embryonic fibroblast - rat  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-02-09 MGC109519  similar to tropomyosin 1, embryonic fibroblast - rat      Symbol and Name status set to provisional 70820 PROVISIONAL