Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Ddx58 (DEXD/H-box helicase 58) Rattus norvegicus
Analyze
Symbol: Ddx58
Name: DEXD/H-box helicase 58
Description: Predicted to have several functions, including nucleic acid binding activity; ubiquitin protein ligase binding activity; and zinc ion binding activity. Predicted to be involved in several processes, including cellular response to exogenous dsRNA; positive regulation of cytokine production; and regulation of transcription, DNA-templated. Predicted to localize to several cellular components, including the actin cytoskeleton; bicellular tight junction; and ruffle membrane. Orthologous to human DDX58 (DExD/H-box helicase 58); PARTICIPATES IN hepatitis C pathway; influenza A pathway; measles pathway; INTERACTS WITH 3,3',5,5'-tetrabromobisphenol A; all-trans-retinoic acid; amphetamine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: DEAD (Asp-Glu-Ala-Asp) box polypeptide 58; LOC297989; probable ATP-dependent RNA helicase DDX58
Orthologs:
Homo sapiens (human) : DDX58 (DExD/H-box helicase 58)  HGNC  Alliance
Mus musculus (house mouse) : Ddx58 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 58)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ddx58 (DExD/H-box helicase 58)
Pan paniscus (bonobo/pygmy chimpanzee) : DDX58 (DExD/H-box helicase 58)
Canis lupus familiaris (dog) : DDX58 (DExD/H-box helicase 58)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ddx58 (DExD/H-box helicase 58)
Sus scrofa (pig) : DDX58 (DExD/H-box helicase 58)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0556,486,584 - 56,536,898 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl556,500,734 - 56,536,772 (-)Ensembl
Rnor_5.0561,033,071 - 61,080,788 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4557,597,131 - 57,645,147 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1557,599,100 - 57,645,200 (-)NCBI
Celera553,939,534 - 53,986,275 (-)NCBICelera
Cytogenetic Map5q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Ddx58
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1309460
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.