Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Brinp1 | Rat | 2,3',4,4',5-Pentachlorobiphenyl | increases expression | ISO | Brinp1 (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:31388691 | Brinp1 | Rat | 3,3',4,4',5-pentachlorobiphenyl | decreases expression | EXP | | 6480464 | 3 more ... | CTD | PMID:23196670 | Brinp1 | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | Brinp1 (Mus musculus) | 6480464 | bisphenol S results in increased expression of BRINP1 mRNA | CTD | PMID:30951980 | Brinp1 | Rat | 4,4'-sulfonyldiphenol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of BRINP1 mRNA | CTD | PMID:36041667 | Brinp1 | Rat | 5-aza-2'-deoxycytidine | multiple interactions | ISO | BRINP1 (Homo sapiens) | 6480464 | [Decitabine co-treated with trichostatin A] inhibits the reaction [sodium arsenite affects the methylation of BRINP1 promoter] and Decitabine inhibits the reaction [sodium arsenite affects the methylation of BRINP1 promoter] | CTD | PMID:18448484 | Brinp1 | Rat | 5-aza-2'-deoxycytidine | affects expression | ISO | BRINP1 (Homo sapiens) | 6480464 | Decitabine affects the expression of BRINP1 mRNA | CTD | PMID:23300844 | Brinp1 | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of BRINP1 mRNA | CTD | PMID:24780913 | Brinp1 | Rat | 8-Br-cAMP | increases expression | ISO | BRINP1 (Homo sapiens) | 6480464 | 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of BRINP1 mRNA | CTD | PMID:20147733 | Brinp1 | Rat | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of BRINP1 mRNA | CTD | PMID:28959563 | Brinp1 | Rat | aflatoxin B1 | decreases methylation | ISO | BRINP1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of BRINP1 gene | CTD | PMID:27153756 | Brinp1 | Rat | aflatoxin B1 | increases methylation | ISO | BRINP1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of BRINP1 intron | CTD | PMID:30157460 | Brinp1 | Rat | all-trans-retinoic acid | increases expression | ISO | BRINP1 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of BRINP1 mRNA | CTD | PMID:23724009 | Brinp1 | Rat | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of BRINP1 mRNA | CTD | PMID:16483693 | Brinp1 | Rat | aristolochic acid A | decreases expression | ISO | BRINP1 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of BRINP1 mRNA | CTD | PMID:33212167 | Brinp1 | Rat | arsenite(3-) | increases methylation | ISO | BRINP1 (Homo sapiens) | 6480464 | arsenite results in increased methylation of BRINP1 promoter | CTD | PMID:23974009 | Brinp1 | Rat | arsenous acid | increases expression | ISO | BRINP1 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of BRINP1 mRNA | CTD | PMID:15761015 | Brinp1 | Rat | atrazine | decreases expression | EXP | | 6480464 | Atrazine results in decreased expression of BRINP1 mRNA | CTD | PMID:36841081 | Brinp1 | Rat | benzo[a]pyrene | decreases methylation | ISO | BRINP1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of BRINP1 promoter | CTD | PMID:27901495 | Brinp1 | Rat | benzo[a]pyrene | affects methylation | ISO | BRINP1 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of BRINP1 5' UTR and Benzo(a)pyrene affects the methylation of BRINP1 intron | CTD | PMID:27901495 and PMID:30157460 | Brinp1 | Rat | benzo[b]fluoranthene | increases expression | ISO | Brinp1 (Mus musculus) | 6480464 | benzo(b)fluoranthene results in increased expression of BRINP1 mRNA | CTD | PMID:26377693 | Brinp1 | Rat | benzo[e]pyrene | increases methylation | ISO | BRINP1 (Homo sapiens) | 6480464 | benzo(e)pyrene results in increased methylation of BRINP1 intron | CTD | PMID:30157460 | Brinp1 | Rat | beta-naphthoflavone | increases expression | ISO | BRINP1 (Homo sapiens) | 6480464 | beta-Naphthoflavone results in increased expression of BRINP1 mRNA | CTD | PMID:19737606 | Brinp1 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of BRINP1 mRNA | CTD | PMID:25181051 | Brinp1 | Rat | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of BRINP1 mRNA | CTD | PMID:36041667 | Brinp1 | Rat | bisphenol A | increases methylation | ISO | BRINP1 (Homo sapiens) | 6480464 | bisphenol A results in increased methylation of BRINP1 gene | CTD | PMID:31601247 | Brinp1 | Rat | bisphenol A | decreases expression | ISO | BRINP1 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of BRINP1 mRNA | CTD | PMID:33670352 | Brinp1 | Rat | bisphenol A | increases expression | ISO | Brinp1 (Mus musculus) | 6480464 | bisphenol A results in increased expression of BRINP1 mRNA | CTD | PMID:30951980 | Brinp1 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of BRINP1 mRNA | CTD | PMID:30816183 | Brinp1 | Rat | bisphenol A | decreases expression | ISO | Brinp1 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of BRINP1 mRNA | CTD | PMID:26063408 and PMID:32156529 | Brinp1 | Rat | bisphenol F | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of BRINP1 mRNA | CTD | PMID:36041667 | Brinp1 | Rat | calcitriol | increases expression | ISO | BRINP1 (Homo sapiens) | 6480464 | Calcitriol results in increased expression of BRINP1 mRNA | CTD | PMID:26485663 | Brinp1 | Rat | carbon nanotube | increases expression | ISO | Brinp1 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | Brinp1 | Rat | CGP 52608 | multiple interactions | ISO | BRINP1 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to BRINP1 gene] | CTD | PMID:28238834 | Brinp1 | Rat | cisplatin | affects expression | ISO | BRINP1 (Homo sapiens) | 6480464 | Cisplatin affects the expression of BRINP1 mRNA | CTD | PMID:23300844 | Brinp1 | Rat | copper atom | increases expression | EXP | | 6480464 | Copper deficiency results in increased expression of BRINP1 mRNA | CTD | PMID:26033743 | Brinp1 | Rat | copper(0) | increases expression | EXP | | 6480464 | Copper deficiency results in increased expression of BRINP1 mRNA | CTD | PMID:26033743 | Brinp1 | Rat | Cuprizon | decreases expression | EXP | | 6480464 | Cuprizone results in decreased expression of BRINP1 mRNA | CTD | PMID:26577399 | Brinp1 | Rat | cyclosporin A | decreases expression | ISO | BRINP1 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of BRINP1 mRNA | CTD | PMID:20106945 | Brinp1 | Rat | diarsenic trioxide | increases expression | ISO | BRINP1 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of BRINP1 mRNA | CTD | PMID:15761015 | Brinp1 | Rat | diazinon | affects expression | EXP | | 6480464 | Diazinon affects the expression of BRINP1 mRNA | CTD | PMID:22546817 | Brinp1 | Rat | dichloroacetic acid | increases expression | ISO | Brinp1 (Mus musculus) | 6480464 | Dichloroacetic Acid results in increased expression of BRINP1 mRNA | CTD | PMID:28962523 | Brinp1 | Rat | dieldrin | affects expression | EXP | | 6480464 | Dieldrin affects the expression of BRINP1 mRNA | CTD | PMID:22546817 | Brinp1 | Rat | dioxygen | multiple interactions | ISO | Brinp1 (Mus musculus) | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of BRINP1 mRNA | CTD | PMID:30529165 | Brinp1 | Rat | diuron | increases expression | EXP | | 6480464 | Diuron results in increased expression of BRINP1 mRNA | CTD | PMID:21551480 | Brinp1 | Rat | dorsomorphin | multiple interactions | ISO | BRINP1 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Brinp1 | Rat | entinostat | increases expression | ISO | BRINP1 (Homo sapiens) | 6480464 | entinostat results in increased expression of BRINP1 mRNA | CTD | PMID:26272509 | Brinp1 | Rat | entinostat | multiple interactions | ISO | BRINP1 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BRINP1 mRNA | CTD | PMID:27188386 | Brinp1 | Rat | flavonoids | decreases expression | EXP | | 6480464 | Flavonoids results in decreased expression of BRINP1 mRNA | CTD | PMID:18035473 | Brinp1 | Rat | genistein | increases expression | ISO | Brinp1 (Mus musculus) | 6480464 | Genistein results in increased expression of BRINP1 mRNA | CTD | PMID:32186404 | Brinp1 | Rat | methapyrilene | increases methylation | ISO | BRINP1 (Homo sapiens) | 6480464 | Methapyrilene results in increased methylation of BRINP1 intron | CTD | PMID:30157460 | Brinp1 | Rat | methylmercury chloride | increases expression | ISO | BRINP1 (Homo sapiens) | 6480464 | methylmercuric chloride results in increased expression of BRINP1 mRNA | CTD | PMID:23179753 | Brinp1 | Rat | O-methyleugenol | decreases expression | ISO | BRINP1 (Homo sapiens) | 6480464 | methyleugenol results in decreased expression of BRINP1 mRNA | CTD | PMID:32234424 | Brinp1 | Rat | panobinostat | multiple interactions | ISO | BRINP1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BRINP1 mRNA | CTD | PMID:27188386 | Brinp1 | Rat | panobinostat | increases expression | ISO | BRINP1 (Homo sapiens) | 6480464 | panobinostat results in increased expression of BRINP1 mRNA | CTD | PMID:26272509 | Brinp1 | Rat | perfluorononanoic acid | decreases expression | ISO | BRINP1 (Homo sapiens) | 6480464 | perfluoro-n-nonanoic acid results in decreased expression of BRINP1 mRNA | CTD | PMID:32588087 | Brinp1 | Rat | perfluorooctane-1-sulfonic acid | decreases expression | ISO | BRINP1 (Homo sapiens) | 6480464 | perfluorooctane sulfonic acid results in decreased expression of BRINP1 mRNA | CTD | PMID:32588087 | Brinp1 | Rat | perfluorooctanoic acid | decreases expression | ISO | BRINP1 (Homo sapiens) | 6480464 | perfluorooctanoic acid results in decreased expression of BRINP1 mRNA | CTD | PMID:32588087 | Brinp1 | Rat | resveratrol | multiple interactions | ISO | BRINP1 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of BRINP1 mRNA | CTD | PMID:23557933 | Brinp1 | Rat | rotenone | decreases expression | ISO | BRINP1 (Homo sapiens) | 6480464 | Rotenone results in decreased expression of BRINP1 mRNA | CTD | PMID:29955902 | Brinp1 | Rat | SB 431542 | multiple interactions | ISO | BRINP1 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Brinp1 | Rat | sodium arsenite | multiple interactions | ISO | BRINP1 (Homo sapiens) | 6480464 | [Decitabine co-treated with trichostatin A] inhibits the reaction [sodium arsenite affects the methylation of BRINP1 promoter] more ... | CTD | PMID:18448484 | Brinp1 | Rat | sodium arsenite | increases expression | ISO | Brinp1 (Mus musculus) | 6480464 | sodium arsenite results in increased expression of BRINP1 mRNA | CTD | PMID:37682722 | Brinp1 | Rat | sodium arsenite | decreases expression | ISO | BRINP1 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of BRINP1 mRNA | CTD | PMID:18448484 | Brinp1 | Rat | sodium dodecyl sulfate | increases expression | ISO | BRINP1 (Homo sapiens) | 6480464 | Sodium Dodecyl Sulfate results in increased expression of BRINP1 mRNA | CTD | PMID:31734321 | Brinp1 | Rat | sunitinib | increases expression | ISO | BRINP1 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of BRINP1 mRNA | CTD | PMID:31533062 | Brinp1 | Rat | thapsigargin | decreases expression | ISO | BRINP1 (Homo sapiens) | 6480464 | Thapsigargin results in decreased expression of BRINP1 mRNA | CTD | PMID:22378314 | Brinp1 | Rat | trichostatin A | multiple interactions | ISO | BRINP1 (Homo sapiens) | 6480464 | [decitabine co-treated with trichostatin A] inhibits the reaction [sodium arsenite affects the methylation of BRINP1 promoter] | CTD | PMID:18448484 | Brinp1 | Rat | trichostatin A | increases expression | ISO | BRINP1 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of BRINP1 mRNA | CTD | PMID:24935251 | Brinp1 | Rat | tunicamycin | decreases expression | ISO | BRINP1 (Homo sapiens) | 6480464 | Tunicamycin results in decreased expression of BRINP1 mRNA | CTD | PMID:22378314 | Brinp1 | Rat | valproic acid | affects expression | ISO | BRINP1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of BRINP1 mRNA | CTD | PMID:25979313 | Brinp1 | Rat | valproic acid | increases expression | ISO | BRINP1 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of BRINP1 mRNA | CTD | PMID:23179753 more ... | Brinp1 | Rat | valproic acid | multiple interactions | ISO | BRINP1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BRINP1 mRNA | CTD | PMID:27188386 | |