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Gene: Alg2 (ALG2, alpha-1,3/1,6-mannosyltransferase) Rattus norvegicus
Symbol: Alg2
Name: ALG2, alpha-1,3/1,6-mannosyltransferase
Description: Predicted to have several functions, including alpha-1,3-mannosyltransferase activity; calcium-dependent protein binding activity; and protein heterodimerization activity. Predicted to be involved in dolichol-linked oligosaccharide biosynthetic process; protein glycosylation in endoplasmic reticulum; and response to calcium ion. Predicted to localize to several cellular components, including actin cytoskeleton; cytosol; and perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Ii and congenital myasthenic syndrome 14. Orthologous to human ALG2 (ALG2 alpha-1,3/1,6-mannosyltransferase); PARTICIPATES IN N-linked glycan biosynthetic pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: alpha-1,3-mannosyltransferase ALG2; alpha-1,3/1,6-mannosyltransferase ALG2; asparagine-linked glycosylation 2 homolog (S. cerevisiae, alpha-1,3-mannosyltransferase); asparagine-linked glycosylation 2 homolog (yeast, alpha-1,3-mannosyltransferase); asparagine-linked glycosylation 2, alpha-1,3-mannosyltransferase homolog; asparagine-linked glycosylation 2, alpha-1,3-mannosyltransferase homolog (S. cerevisiae); LOC313231
Homo sapiens (human) : ALG2 (ALG2 alpha-1,3/1,6-mannosyltransferase)  HGNC  Alliance
Mus musculus (house mouse) : Alg2 (asparagine-linked glycosylation 2 (alpha-1,3-mannosyltransferase))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Alg2 (ALG2 alpha-1,3/1,6-mannosyltransferase)
Pan paniscus (bonobo/pygmy chimpanzee) : ALG2 (ALG2 alpha-1,3/1,6-mannosyltransferase)
Canis lupus familiaris (dog) : ALG2 (ALG2 alpha-1,3/1,6-mannosyltransferase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Alg2 (ALG2 alpha-1,3/1,6-mannosyltransferase)
Sus scrofa (pig) : ALG2 (ALG2 alpha-1,3/1,6-mannosyltransferase)
Chlorocebus sabaeus (African green monkey) : ALG2 (ALG2 alpha-1,3/1,6-mannosyltransferase)
Heterocephalus glaber (naked mole-rat) : Alg2 (ALG2 alpha-1,3/1,6-mannosyltransferase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0563,187,466 - 63,192,025 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl563,187,468 - 63,192,025 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0567,707,025 - 67,711,584 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4564,092,017 - 64,096,576 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1564,098,709 - 64,101,565 (-)NCBI
Celera565,819,685 - 65,824,244 (+)NCBICelera
Cytogenetic Map5q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Alg2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1309940
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.