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Gene: Alg2 (ALG2, alpha-1,3/1,6-mannosyltransferase) Rattus norvegicus
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Symbol: Alg2
Name: ALG2, alpha-1,3/1,6-mannosyltransferase
Description: Predicted to have several functions, including alpha-1,3-mannosyltransferase activity; calcium-dependent protein binding activity; and protein heterodimerization activity. Predicted to be involved in dolichol-linked oligosaccharide biosynthetic process; protein glycosylation in endoplasmic reticulum; and response to calcium ion. Predicted to localize to several cellular components, including actin cytoskeleton; cytosol; and perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Ii and congenital myasthenic syndrome 14. Orthologous to human ALG2 (ALG2 alpha-1,3/1,6-mannosyltransferase); PARTICIPATES IN N-linked glycan biosynthetic pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: alpha-1,3-mannosyltransferase ALG2; alpha-1,3/1,6-mannosyltransferase ALG2; asparagine-linked glycosylation 2 homolog (S. cerevisiae, alpha-1,3-mannosyltransferase); asparagine-linked glycosylation 2 homolog (yeast, alpha-1,3-mannosyltransferase); asparagine-linked glycosylation 2, alpha-1,3-mannosyltransferase homolog; asparagine-linked glycosylation 2, alpha-1,3-mannosyltransferase homolog (S. cerevisiae); LOC313231
Orthologs:
Homo sapiens (human) : ALG2 (ALG2 alpha-1,3/1,6-mannosyltransferase)  HGNC  Alliance
Mus musculus (house mouse) : Alg2 (asparagine-linked glycosylation 2 (alpha-1,3-mannosyltransferase))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Alg2 (ALG2 alpha-1,3/1,6-mannosyltransferase)
Pan paniscus (bonobo/pygmy chimpanzee) : ALG2 (ALG2 alpha-1,3/1,6-mannosyltransferase)
Canis lupus familiaris (dog) : ALG2 (ALG2 alpha-1,3/1,6-mannosyltransferase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Alg2 (ALG2 alpha-1,3/1,6-mannosyltransferase)
Sus scrofa (pig) : ALG2 (ALG2 alpha-1,3/1,6-mannosyltransferase)
Chlorocebus sabaeus (African green monkey) : ALG2 (ALG2 alpha-1,3/1,6-mannosyltransferase)
Heterocephalus glaber (naked mole-rat) : Alg2 (ALG2 alpha-1,3/1,6-mannosyltransferase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0563,187,466 - 63,192,025 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl563,187,468 - 63,192,025 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0567,707,025 - 67,711,584 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4564,092,017 - 64,096,576 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1564,098,709 - 64,101,565 (-)NCBI
Celera565,819,685 - 65,824,244 (+)NCBICelera
Cytogenetic Map5q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Alg2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1309940
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.