Mob3b (MOB kinase activator 3B) - Rat Genome Database

Name: Mob3b
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Mob3b (MOB kinase activator 3B) Rattus norvegicus

Analyze

Symbol:

Mob3b

Name:

MOB kinase activator 3B

RGD ID:

1560696

Description:

Predicted to enable protein kinase activator activity. Predicted to be involved in positive regulation of protein phosphorylation; regulation of hippo signaling; and signal transduction. Predicted to be active in cytoplasm and nucleus. Orthologous to human MOB3B (MOB kinase activator 3B); INTERACTS WITH 6-propyl-2-thiouracil; amphetamine; bisphenol A.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC102550026; LOC366352; MOB kinase activator 3B-like; MOB1, Mps One Binder kinase activator-like 2B; MOB1, Mps One Binder kinase activator-like 2B (yeast); Mobkl2b; mps one binder kinase activator-like 2B; RGD1560696; similar to Mob3b protein; uncharacterized LOC102550026

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	MOB3B (MOB kinase activator 3B)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Mob3b (MOB kinase activator 3B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Mob3b (MOB kinase activator 3B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	MOB3B (MOB kinase activator 3B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	MOB3B (MOB kinase activator 3B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Mob3b (MOB kinase activator 3B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	MOB3B (MOB kinase activator 3B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Mob3b (MOB kinase activator 3B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Mob3b (MOB kinase activator 3B)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	MOB3B (MOB kinase activator 3B)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	MOB1	Alliance	DIOPT (InParanoid\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Mob3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	mob-3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	5	49,541,804 - 49,737,934 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	49,545,815 - 49,737,934 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	51,739,475 - 51,931,145 (-)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	5	53,339,724 - 53,531,407 (-)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	5	53,241,656 - 53,433,259 (-)	NCBI	Rnor_WKY
Rnor_6.0	5	50,437,444 - 50,638,136 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	50,438,576 - 50,638,136 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	55,006,398 - 55,201,845 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	51,616,232 - 51,809,856 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	5	48,289,837 - 48,481,822 (-)	NCBI		Celera
Cytogenetic Map	5	q21	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,1-dichloroethene (ISO)

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

6-propyl-2-thiouracil (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

amphetamine (EXP)

aristolochic acid (ISO)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

butanal (ISO)

cadmium dichloride (EXP)

carbon nanotube (ISO)

chlordecone (ISO)

cisplatin (ISO)

copper atom (ISO)

copper(0) (ISO)

copper(II) sulfate (ISO)

CU-O LINKAGE (ISO)

Cuprizon (EXP)

cyclosporin A (ISO)

dexamethasone (ISO)

diazinon (ISO)

dibutyl phthalate (ISO)

dioxygen (ISO)

disodium selenite (ISO)

dorsomorphin (ISO)

endosulfan (EXP)

entinostat (ISO)

fenthion (ISO)

furan (ISO)

gentamycin (EXP)

hydroquinone (ISO)

indometacin (ISO)

manganese(II) chloride (EXP)

methidathion (ISO)

methylmercury chloride (ISO)

N-methyl-4-phenylpyridinium (ISO)

nickel atom (ISO)

paracetamol (EXP)

pentanal (ISO)

perfluorooctane-1-sulfonic acid (ISO)

pirinixic acid (ISO)

potassium chromate (ISO)

progesterone (ISO)

propanal (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

Soman (EXP)

sulforaphane (ISO)

tetrachloromethane (EXP,ISO)

tremolite asbestos (ISO)

trichostatin A (ISO)

troglitazone (ISO)

trovafloxacin (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

activation of protein kinase activity (IEA)

positive regulation of protein phosphorylation (IBA)

regulation of hippo signaling (ISO)

signal transduction (IBA)

Cellular Component

cytoplasm (IBA)

nucleus (IBA)

Molecular Function

protein binding (ISO)

protein kinase activator activity (IBA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:28792927

Genomics

Comparative Map Data

Mob3b
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	5	49,541,804 - 49,737,934 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	49,545,815 - 49,737,934 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	51,739,475 - 51,931,145 (-)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	5	53,339,724 - 53,531,407 (-)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	5	53,241,656 - 53,433,259 (-)	NCBI	Rnor_WKY
Rnor_6.0	5	50,437,444 - 50,638,136 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	50,438,576 - 50,638,136 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	55,006,398 - 55,201,845 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	51,616,232 - 51,809,856 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	5	48,289,837 - 48,481,822 (-)	NCBI		Celera
Cytogenetic Map	5	q21	NCBI

MOB3B
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	9	27,325,209 - 27,529,814 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	9	27,325,209 - 27,529,814 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	9	27,325,207 - 27,529,812 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	27,315,207 - 27,519,850 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	9	27,315,207 - 27,519,850	NCBI
Celera	9	27,253,352 - 27,457,971 (-)	NCBI		Celera
Cytogenetic Map	9	p21.2	NCBI
HuRef	9	27,277,716 - 27,482,639 (-)	NCBI		HuRef
CHM1_1	9	27,324,996 - 27,529,642 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	9	27,335,803 - 27,540,380 (-)	NCBI		T2T-CHM13v2.0

Mob3b
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	34,949,074 - 35,157,490 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	34,949,074 - 35,157,484 (-)	Ensembl		GRCm39 Ensembl
GRCm38	4	34,949,074 - 35,157,524 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	34,949,074 - 35,157,484 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	34,899,953 - 35,104,715 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	35,141,591 - 35,346,353 (-)	NCBI		MGSCv36	mm8
MGSCv36	4	34,609,498 - 34,815,906 (-)	NCBI		MGSCv36	mm8
Celera	4	34,682,511 - 34,873,721 (-)	NCBI		Celera
Cytogenetic Map	4	A5	NCBI
cM Map	4	16.86	NCBI

Mob3b
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955472	7,425,819 - 7,530,719 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955472	7,381,248 - 7,535,818 (+)	NCBI	ChiLan1.0	ChiLan1.0

MOB3B
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	9	27,778,739 - 27,983,880 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	9	27,784,106 - 27,909,354 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	9	27,172,685 - 27,378,196 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

MOB3B
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	11	45,456,049 - 45,574,034 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	11	45,460,901 - 45,574,034 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	11	44,132,551 - 44,323,212 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	11	46,401,892 - 46,592,947 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	11	46,405,651 - 46,592,952 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	11	45,057,960 - 45,248,366 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	11	44,948,160 - 45,145,340 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	11	45,694,768 - 45,885,793 (-)	NCBI		UU_Cfam_GSD_1.0

Mob3b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	160,352,109 - 160,543,161 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936611	2,125,069 - 2,312,698 (+)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936611	2,125,249 - 2,312,943 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MOB3B
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	10	38,438,346 - 38,680,995 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	10	38,437,933 - 38,694,667 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	10	43,580,268 - 43,668,235 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Mob3b
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624736	31,552,912 - 31,667,100 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624736	31,534,327 - 31,735,163 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Mob3b
1035 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	180
Count of miRNA genes:	129
Interacting mature miRNAs:	151
Transcripts:	ENSRNOT00000012519
Prediction methods:	Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1331756	Rf34	Renal function QTL 34	4.16275		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	5	1	90450412	Rat
70212	Niddm25	Non-insulin dependent diabetes mellitus QTL 25	3.54		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	5	1	131345958	Rat
1331771	Rf35	Renal function QTL 35	4.36965		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	5	729470	86724018	Rat
1576314	Eutr1	Estrogen induced uterine response QTL 1			uterus integrity trait (VT:0010575)	pyometritis severity score (CMO:0002009)	5	2138965	166875058	Rat
8662454	Vetf3	Vascular elastic tissue fragility QTL 3	27.4		artery integrity trait (VT:0010639)	number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)	5	2282226	69540447	Rat
2293666	Bmd38	Bone mineral density QTL 38	4.4		femur size trait (VT:1000369)	femoral neck cortical cross-sectional area (CMO:0001702)	5	8948228	53948228	Rat
7394712	Emca13	Estrogen-induced mammary cancer QTL 13			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	9823266	99753708	Rat
1641903	Alcrsp3	Alcohol response QTL 3			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	5	12689285	57689285	Rat
634305	Mamtr1	Mammary tumor resistance QTL 1		0.0001	mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	12789751	113558310	Rat
1600358	Mamtr5	Mammary tumor resistance QTL 5			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	18873947	63873947	Rat
1358353	Srcrtb2	Stress Responsive Cort Basal QTL 2	3.48	0.003	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	5	18873947	74251464	Rat
8552954	Pigfal14	Plasma insulin-like growth factor 1 level QTL 14	9		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	21226744	66226744	Rat
1578767	Stresp17	Stress response QTL 17	4.3	0.01	blood aldosterone amount (VT:0005346)	plasma aldosterone level (CMO:0000551)	5	27955440	72955440	Rat
1578776	Stresp18	Stress response QTL 18	2.9		thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	5	27955440	72955440	Rat
6903292	Stl28	Serum triglyceride level QTL 28	2.6	0.0073	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	5	28515489	73515489	Rat
6903306	Scl35	Serum cholesterol QTL 35	2.6	0.0073	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	28515489	73515489	Rat
2290448	Scl54	Serum cholesterol level QTL 54	2.93		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	31663789	131345958	Rat
1598807	Glom12	Glomerulus QTL 12	2.7		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	5	33215665	78215665	Rat
1298067	Scl15	Serum cholesterol level QTL 15	4.8	0.001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	33215665	78215665	Rat
1302786	Kidm8	Kidney mass QTL 8	28.15		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	5	33215665	78215665	Rat
1576317	Eutr2	Estrogen induced uterine response QTL 2		0.01	uterus integrity trait (VT:0010575)	pyometritis severity score (CMO:0002009)	5	34730116	104251008	Rat
2316959	Gluco59	Glucose level QTL 59	4.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	5	34944474	113558310	Rat
1641922	Alcrsp8	Alcohol response QTL 8			alcohol metabolism trait (VT:0015089)	blood ethanol level (CMO:0000535)	5	35189153	68564008	Rat
1641912	Alcrsp18	Alcohol response QTL 18			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	5	35189153	141643988	Rat
1549845	Scl44	Serum cholesterol level QTL 44	6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	40128307	148607290	Rat
1331773	Scl26	Serum cholesterol level QTL 26	3.065		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	43726656	86724018	Rat
1331801	Rf33	Renal function QTL 33	4.149		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	5	43726656	129132602	Rat
1578766	Tcas11	Tongue tumor susceptibility QTL 11	4.12		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	5	46711509	161317411	Rat
1300115	Hrtrt7	Heart rate QTL 7	2.76		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	5	47869062	90099692	Rat
9589025	Epfw7	Epididymal fat weight QTL 7	20.66	0.001	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	5	49463600	94463600	Rat
7411561	Bw134	Body weight QTL 134	24	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	49463600	94463600	Rat

Markers in Region

D5Rat254

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	49,593,783 - 49,593,924 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	51,197,517 - 51,197,657	NCBI	Rnor6.0
Rnor_6.0	5	50,486,539 - 50,486,679	NCBI	Rnor6.0
Rnor_5.0	5	55,757,348 - 55,757,488	UniSTS	Rnor5.0
Rnor_5.0	5	55,055,493 - 55,055,633	UniSTS	Rnor5.0
RGSC_v3.4	5	51,664,209 - 51,664,350	RGD	RGSC3.4
RGSC_v3.4	5	51,664,210 - 51,664,350	UniSTS	RGSC3.4
RGSC_v3.1	5	51,664,388 - 51,664,529	RGD
Celera	5	48,337,575 - 48,337,715	UniSTS
FHH x ACI Map	5	29.14	UniSTS
FHH x ACI Map	5	29.14	RGD
Cytogenetic Map	5	q21-q22	UniSTS

BE105239

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	10	79,246,664 - 79,247,408 (+)	MAPPER	mRatBN7.2
mRatBN7.2	5	49,654,204 - 49,654,403 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	50,552,703 - 50,552,901	NCBI	Rnor6.0
Rnor_6.0	10	81,997,248 - 81,997,991	NCBI	Rnor6.0
Rnor_5.0	10	81,830,061 - 81,830,804	UniSTS	Rnor5.0
Rnor_5.0	5	55,119,460 - 55,119,658	UniSTS	Rnor5.0
RGSC_v3.4	10	82,936,187 - 82,936,930	UniSTS	RGSC3.4
RGSC_v3.4	5	51,725,332 - 51,725,530	UniSTS	RGSC3.4
Celera	5	48,398,023 - 48,398,221	UniSTS
Celera	10	78,035,466 - 78,036,209	UniSTS
RH 3.4 Map	5	269.7	UniSTS
Cytogenetic Map	5	q21-q22	UniSTS
Cytogenetic Map	10	q26	UniSTS
Cytogenetic Map	5	q22	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium			4	4	1	4			4	12	2
Low	3	31	53	37	18	37	6	8	70	23	35	11	6
Below cutoff		12					2	3			4		2

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001108970	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006238001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017593536	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473962	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ220583	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ222144	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000161	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000012519 ⟹ ENSRNOP00000012519

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	49,545,815 - 49,737,934 (-)	Ensembl
Rnor_6.0 Ensembl	5	50,438,576 - 50,638,136 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000080713

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	5	51,148,371 - 51,184,078 (-)	Ensembl

RefSeq Acc Id:

NM_001108970 ⟹ NP_001102440

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	5	49,545,815 - 49,737,934 (-)	NCBI
Rnor_6.0	5	50,438,576 - 50,638,136 (-)	NCBI
Rnor_5.0	5	55,006,398 - 55,201,845 (-)	NCBI
RGSC_v3.4	5	51,616,232 - 51,809,856 (-)	RGD
Celera	5	48,289,837 - 48,481,822 (-)	RGD

Sequence:

show sequence

GGCGAGCTGCGCGGCGCGCTGGGTGCATGTGGGGGCCGCATCAGAGCCGTGGCCGCTGCATCTG
GAGTCACGCGTGCTGGCTAGAGAGCCCCTCGCGTGAATCTGCAACATCGCTGCTCGGGTTGGAG
GAGTTCACTCTTTTTCTCCCGCTCCAGAAGCTGCTGCCGGCGTGAAGGAAGCCAGCAGGGCCCT
AGGAAGAAGGTTAAAACCCCACGGAAGGAACATGAAGTTCCCTTGGAGATCATTCAAGAGGACG
ATGGAGGGAGGCATTTAGAGTAAACCGAGTTAAAAACCACAGGCTGCCACCCTGGGGCCTGAGG
GCTGGCAGTGGAAACGCCTGCTGGGCTGTGACCTCTCACTGAAAAGTCCCAAGTGCCTTTTTGC
TTCCTGCAAAAGGAAGGAAGCCAAGGAAGAGACCATGTCCATAGCCCTGAAGCAAGTGTTCAAC
AAGGACAAGACCTTCCGGCCCAAGAGGAAGTTCGAACCCGGCACACAGAGATTCGAGCTGCACA
AACGGGCTCAGGCATCCCTCAACTCGGGTGTGGACCTGAGGGCAGCTGTACAGTTACCGAGCGG
GGAGGACCAGAACGACTGGGTGGCTGTGCACGTGGTGGACTTCTTCAATCGCATCAACCTCATT
TACGGCACGATCTGTGAGTTCTGCACTGAGCGGACCTGCCCTGTGATGTCGGGGGGCCCCAAAT
ACGAGTATCGGTGGCAGGATGACCTCAAGTATAAGAAGCCAACCGCACTGCCCGCTCCCCAGTA
CATGAACCTGCTTATGGATTGGATTGAAGTCCAGATAAACAATGAGGACATATTTCCAACATGT
GTCGGCGTTCCCTTCCCAAAGAACTTCCTCCAGATCTGCAAGAAGATCCTGTGCCGTCTTTTTC
GGGTGTTCGTCCACGTCTACATCCACCATTTTGACCGCGTCATTGTGATGGGTGCAGAGGCTCA
CGTCAACACCTGCTACAAACACTTCTATTACTTTGTCACAGAGATGAACCTCATAGACCGCAAG
GAGCTGGAGCCCTTGAAAGAGATGACAACCAGGATGTGTCACTAACACTCCACCCCATCTTCTG
GAAGGAAGGAACACTGTTTCTCCCAGGAGTCCCCATGGGACAGAAAGTGGTCCTCTGTGAATGA
AATGATCCCGGAGCAGGAAAGCTGCAGCCCCACAAGGACTTCTGAAAGACGTTCCTTACCTACT
TCACGTGCTCTTAACCCTCTAAGTGCTGCTAGCCAGGACCTGTGGGCCATACAGACCACAGCAT
GAAGGACCAGCCTTAACCCCTTGGGCCAAGGACAGTGCAGGAGAGGTTGCTGCACTTCCGCCCA
CATCACACTTCTGCCCGTGACCGGTCCTCTAGGCTTTACTGGAATTCAGGTTTTGAGACTGAGG
GGTTTTGTTGTGGTGGTTCTTTTCCATTTATGTCTTGTCAGACTTCTGGACTAACTTCTCTGTC
ACTTATTTTTCTAAGTTCTAGGCACACGCGTACCATATAGACAGTACGTTTCCTATCCCATCTC
TCCTCGACTCCCTGCAGGCTCCATAACCTTATATGGAGCTTGGAGCTGGGGAAAGGCCACAGTT
CTTCTGGTAGCATCCGTGCCATTTCCCTCATGGGCAGTTTCACCAGAAACCGCTGACTCGATGG
GTGACATGATCTGTGTCCCTGGACAGGCCATTCACATGCTAACCTTTGGAAAGAGTCTGGTGAC
TGGAAATAAAGCTGGTGTGTTATCAGTTTACCCTAGTTGGAATGCATTTGTTGTAGCCACAGTC
ATTTCTAGATGCTTCCATTTAAGATGTGCTTTCCCATTCCCCAGAAGAGAGGAAATGGTTTTAA
AATGACCAGTAAGGTCCTTGAGCCAGATTAGTGCAGTGTTTGTTCTTTATTGAGGGCTAGTGAG
TCCCGGCTGATCCTACATATTATATTATGGAGGTTTCAGCAATAAGACAGCAGACAGTTGGTAC
GTGTATATTAAATACCTCTCTCTCTTATTGTCCCTCCATCTCCTATGCTATATGACACAGAATT
CATTTCAGTCCGGCGGTCTTCCTTCAATCCATTCAATCTGTCCCTTCCAACCCCCAGAATAACC
ATCAGATGCTACGCTGTCTCCTGCCTTTGGAGGTCCTAGTAAACGAATCACTGCCTTCTCTGAT
TTCTTCACAGAGCTGGTTCTGACAGCTTGACTAAGAAGTACCCATACTTCCCCTGATATTTGAT
TTTAATAAAGTATCCTGGTGGAGGGAAGTAG

hide sequence

RefSeq Acc Id:

XM_006238001 ⟹ XP_006238063

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	5	49,541,804 - 49,737,934 (-)	NCBI
Rnor_6.0	5	50,437,444 - 50,638,136 (-)	NCBI
Rnor_5.0	5	55,006,398 - 55,201,845 (-)	NCBI

Sequence:

show sequence

GGCGAGCTGCGCGGCGCGCTGGGTGCATGTGGGGGCCGCATCAGAGCCGTGGCCGCTGCATCTG
GAGTCACGCGTGCTGGCTAGAGAGCCCCTCGCGTGAATCTGCAACATCGCTGCTCGGGTTGGAG
GAGTTCACTCTTTTTCTCCCGCTCCAGAAGCTGCTGCCGGCGTGAAGGAAGCCAGCAGGGCCCT
AGGAAGAAGGTTAAAACCCCACGGAAGGAACATGAAGTTCCCTTGGAGATCATTCAAGAGGACG
ATGGAGGGAGGCATTTAGAGTAAACCGAGTTAAAAACCACAGGCTGCCACCCTGGGGCCTGAGG
GCTGGCAGTGGAAACGCCTGCTGGGCTGTGACCTCTCACTGAAAAGTCCCAAGTGCCTTTTTGC
TTCCTGCAAAAGGAAGGAAGCCAAGGAAGAGACCATGTCCATAGCCCTGAAGCAAGTGTTCAAC
AAGGACAAGACCTTCCGGCCCAAGAGGAAGTTCGAACCCGGCACACAGAGATTCGAGCTGCACA
AACGGGCTCAGGCATCCCTCAACTCGGGTGTGGACCTGAGGGCAGCTGTACAGTTACCGAGCGG
GGAGGACCAGAACGACTGGGTGGCTGTGCACGTGGTGGACTTCTTCAATCGCATCAACCTCATT
TACGGCACGATCTGTGAGTTCTGCACTGAGCGGACCTGCCCTGTGATGTCGGGGGGCCCCAAAT
ACGAGTATCGGTGGCAGGATGACCTCAAGTATAAGAAGCCAACCGCACTGCCCGCTCCCCAGTA
CATGAACCTGCTTATGGATTGGATTGAAGTCCAGATAAACAATGAGGACATATTTCCAACATGT
GTCGGCGTTCCCTTCCCAAAGAACTTCCTCCAGATCTGCAAGAAGATCCTGTGCCGTCTTTTTC
GGGTGTTCGTCCACGTCTACATCCACCATTTTGACCGCGTCATTGTGATGGGTGCAGAGGCTCA
CGTCAACACCTGCTACAAACACTTCTATTACTTTGTCACAGAGATGAACCTCATAGACCGCAAG
GAGCTGGAGCCCTTGAAAGAGATGACAACCAGGATGTGTCACTAACACTCCACCCCATCTTCTG
GAAGGAAGGAACACTGTTTCTCCCAGGAGTCCCCATGGGACAGAAAGTGGTCCTCTGTGAATGA
AATGATCCCGGAGCAGGAAAGCTGCAGCCCCACAAGGACTTCTGAAAGACGTTCCTTACCTACT
TCACGTGCTCTTAACCCTCTAAGTGCTGCTAGCCAGGACCTGTGGGCCATACAGACCACAGCAT
GAAGGACCAGCCTTAACCCCTTGGGCCAAGGACAGTGCAGGAGAGGTTGCTGCACTTCCGCCCA
CATCACACTTCTGCCCGTGACCGGTCCTCTAGGCTTTACTGGAATTCAGGTTTTGAGACTGAGG
GGTTTTGTTGTGGTGGTTCTTTTCCATTTATGTCTTGTCAGACTTCTGGACTAACTTCTCTGTC
ACTTATTTTTCTAAGTTCTAGGCACACGCGTACCATATAGACAGTACGTTTCCTATCCCATCTC
TCCTCGACTCCCTGCAGGCTCCATAACCTTATATGGAGCTTGGAGCTGGGGAAAGGCCACAGTT
CTTCTGGTAGCATCCGTGCCATTTCCCTCATGGGCAGTTTCACCAGAAACCGCTGACTCGATGG
GTGACATGATCTGTGTCCCTGGACAGGCCATTCACATGCTAACCTTTGGAAAGAGTCTGGTGAC
TGGAAATAAAGCTGGTGTGTTATCAGTTTACCCTAGTTGGAATGCATTTGTTGTAGCCACAGTC
ATTTCTAGATGCTTCCATTTAAGATGTGCTTTCCCATTCCCCAGAAGAGAGGAAATGGTTTTAA
AATGACCAGTAAGGTCCTTGAGCCAGATTAGTGCAGTGTTTGTTCTTTATTGAGGGCTAGTGAG
TCCCGGCTGATCCTACATATTATATTATGGAGGTTTCAGCAATAAGACAGCAGACAGTTGGTAC
GTGTATATTAAATACCCTTGACTTACATACAGCCTTCCCAACTTGTCCCCAGAGATTCTGAACC
CAGCTGGTATTTCTTCTCTTCTCTACTTTCCTCTCCTTCCCAGTCTTCCCATTCTTTCATGTGT
GTTCTCTCATCTGTGCGCACCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT
TATTGTCCCTCCATCTCCTATGCTATATGACACAGAATTCATTTCAGTCCGGCGGTCTTCCTTC
AATCCATTCAATCTGTCCCTTCCAACCCCCAGAATAACCATCAGATGCTACGCTGTCTCCTGCC
TTTGGAGGTCCTAGTAAACGAATCACTGCCTTCTCTGATTTCTTCACAGAGCTGGTTCTGACAG
CTTGACTAAGAAGTACCCATACTTCCCCTGATATTTGATTTTAATAAAGTATCCTGGTGGAGGG
AAGTAGATATGAATGTATTCTTGCAGTTGGTGTAATAACAAAAGCCGACTAAGTTAGTCTGATC
TTATTTAGTCTATATAATGTGTTAAAGCCACTCGCAGCCACCACAAAAGCCTAGAAAACATGAC
TTCATTTATGTAAATGAAGAAGCTGACCGTATGGACTCGGTGGCATGACAGATGCAGAACAGCC
CTTACGTCCTGTCTCGTAGACGTTGTCTTCTGAAGCCCAACACAACCACTGCTATATTATTGAC
TTGTTCCAACCTACTGGGATGTTTTTCTTTTCTCCCTAAGTAACTTTAAGAGGCCAAGATAGGC
AATGTTGTTGTTTTGTTTTGTTTTGTTTTTTGTCAATATCAGTTTGGGCTAAAAGCATTCTCTG
GCTGCCCTAAAGGTCCAGAGGAAAAGGAGCCCTGAATTCCTGACCCAGGCAATACATAATACCA
CACATGGGTGTGCAGAATGGTGGGCTGAGAAATGTCAGCCCAGTCCGCTTAGCCTCGGGGAGTC
TCTGCAGCCTTGTACCTTGAATGACTGCAGGACTCACGCAGTAGAAAGTAGAGTATGCTCCTGC
ATTTCAGTGATGCTTAGTCAAAGAGGAAGCCTGATTGAAGACATTTGTCATTTCTGAAGTTATT
TTCTGTCCATTGCTTGGGTGTGTGAAATCTCCGTCTAACTTAAAACATCCAAAAATATTTTTTT
TTAAGTCTTGGAATGATCTTCTTTGGCTTTTATTGCTACTTGCACTAATCAGCTCTTCGGGTAA
AATCTAGCCAACTGCTCTGATTTTTTCAAGTATGAGGTGTTCATAGTCATATAGAACTTTGTTT
GGCAAATTCTAAAAAAAAAGTCTTCATGACTGTCCGTAAGCCTTTGGCCTGCCCTGCTCTCCCA
TGCATCTGTAGTGGGAATGGAAGACCCTTGTAGCCCCTAGGACGGCTCCAAGCCTAGTTCTGTC
TCCTAACCTTGTCTAACATTTATCTTAATTGGGGGGAAATTAAAAGTTGAAAGATCACCACGAG
CACCCTATGTCCATGAGTGTACCAAGTGTTAGCATATTGCCTCGATTTCCTTCTTACTGTAAAT
GCACTCATTGCTGAACCATCAAAAATATAATAAATTACAGTCATCATAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001102440	(Get FASTA)	NCBI Sequence Viewer
	XP_006238063	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL98612	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_001102440 ⟸ NM_001108970

- UniProtKB:

D3ZCN1 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSIALKQVFNKDKTFRPKRKFEPGTQRFELHKRAQASLNSGVDLRAAVQLPSGEDQNDWVAVHV
VDFFNRINLIYGTICEFCTERTCPVMSGGPKYEYRWQDDLKYKKPTALPAPQYMNLLMDWIEVQ
INNEDIFPTCVGVPFPKNFLQICKKILCRLFRVFVHVYIHHFDRVIVMGAEAHVNTCYKHFYYF
VTEMNLIDRKELEPLKEMTTRMCH

hide sequence

RefSeq Acc Id:	XP_006238063 ⟸ XM_006238001
- Peptide Label:	isoform X1
- UniProtKB:	D3ZCN1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSIALKQVFNKDKTFRPKRKFEPGTQRFELHKRAQASLNSGVDLRAAVQLPSGEDQNDWVAVHV VDFFNRINLIYGTICEFCTERTCPVMSGGPKYEYRWQDDLKYKKPTALPAPQYMNLLMDWIEVQ INNEDIFPTCVGVPFPKNFLQICKKILCRLFRVFVHVYIHHFDRVIVMGAEAHVNTCYKHFYYF VTEMNLIDRKELEPLKEMTTRMCH hide sequence

RefSeq Acc Id:

ENSRNOP00000012519 ⟸ ENSRNOT00000012519

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZCN1-F1-model_v2	AlphaFold	D3ZCN1	1-216	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13693624

Promoter ID:

EPDNEW_R4149

Type:

multiple initiation site

Name:

Mob3b_1

Description:

MOB kinase activator 3B

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	50,638,149 - 50,638,209	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1560696	AgrOrtholog
BioCyc Gene	G2FUF-41642	BioCyc
Ensembl Genes	ENSRNOG00000009453	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSRNOG00000058323	Ensembl
Ensembl Protein	ENSRNOP00000012519	ENTREZGENE
	ENSRNOP00000012519.3	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000012519	ENTREZGENE
	ENSRNOT00000012519.4	UniProtKB/TrEMBL
Gene3D-CATH	1.20.140.30	UniProtKB/TrEMBL
InterPro	Mob1_phocein	UniProtKB/TrEMBL
	MOB_kinase_act_sf	UniProtKB/TrEMBL
KEGG Report	rno:366352	UniProtKB/TrEMBL
NCBI Gene	366352	ENTREZGENE
PANTHER	Mob1_phocein	UniProtKB/TrEMBL
Pfam	Mob1_phocein	UniProtKB/TrEMBL
PhenoGen	Mob3b	PhenoGen
SMART	Mob1_phocein	UniProtKB/TrEMBL
Superfamily-SCOP	Mob1_phocein	UniProtKB/TrEMBL
UniProt	D3ZCN1	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-03-09	Mob3b	MOB kinase activator 3B	LOC102550026	uncharacterized LOC102550026	Data Merged	737654	PROVISIONAL
2013-12-17	LOC102550026	uncharacterized LOC102550026			Symbol and Name status set to provisional	70820	PROVISIONAL
2011-10-18	Mob3b	MOB kinase activator 3B	Mobkl2b	MOB1, Mps One Binder kinase activator-like 2B (yeast)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-02-28	Mobkl2b	MOB1, Mps One Binder kinase activator-like 2B (yeast)	RGD1560696_predicted	similar to Mob3b protein (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-07	RGD1560696_predicted	similar to Mob3b protein (predicted)	LOC366352	similar to Mob3b protein	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC366352	similar to Mob3b protein			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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