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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 17beta-hydroxy-5alpha-androstan-3-one | increases expression | ISO | RGD:1320210 | 6480464 | Dihydrotestosterone results in increased expression of CORO2A mRNA | CTD | PMID:29581250 | 2,2',4,4',5,5'-hexachlorobiphenyl | multiple interactions | ISO | RGD:1320211 | 6480464 | [2 more ... | CTD | PMID:25510870 | 2,2',5,5'-tetrachlorobiphenyl | multiple interactions | ISO | RGD:1320211 | 6480464 | [2 more ... | CTD | PMID:25510870 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of CORO2A mRNA | CTD | PMID:22298810 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of CORO2A mRNA | CTD | PMID:32109520, PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:1320211 | 6480464 | Tetrachlorodibenzodioxin affects the expression of CORO2A mRNA | CTD | PMID:21570461, PMID:26377647 | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2, 4-dinitrotoluene affects the expression of CORO2A mRNA | CTD | PMID:21346803 | 2-hydroxypropanoic acid | decreases expression | ISO | RGD:1320210 | 6480464 | Lactic Acid results in decreased expression of CORO2A mRNA | CTD | PMID:30851411 | 3,3',5,5'-tetrabromobisphenol A | increases expression | EXP | | 6480464 | tetrabromobisphenol A results in increased expression of CORO2A mRNA | CTD | PMID:27914987 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | RGD:1320210 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of CORO2A mRNA | CTD | PMID:28628672 | 4,4'-sulfonyldiphenol | multiple interactions | ISO | RGD:1320210 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of CORO2A mRNA | CTD | PMID:28628672 | 4,4'-sulfonyldiphenol | decreases methylation | ISO | RGD:1320211 | 6480464 | bis(4-hydroxyphenyl)sulfone results in decreased methylation of CORO2A exon | CTD | PMID:33297965 | 4-hydroxyphenyl retinamide | increases expression | ISO | RGD:1320211 | 6480464 | Fenretinide results in increased expression of CORO2A mRNA | CTD | PMID:28973697 | 8-Br-cAMP | decreases expression | ISO | RGD:1320210 | 6480464 | 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CORO2A mRNA | CTD | PMID:22079614 | aflatoxin B1 | increases methylation | ISO | RGD:1320210 | 6480464 | Aflatoxin B1 results in increased methylation of CORO2A gene | CTD | PMID:27153756 | all-trans-retinoic acid | increases expression | ISO | RGD:1320210 | 6480464 | Tretinoin results in increased expression of CORO2A mRNA | CTD | PMID:23724009 more ... | amiodarone | increases expression | ISO | RGD:1320210 | 6480464 | Amiodarone results in increased expression of CORO2A mRNA | CTD | PMID:19774075 | aristolochic acid A | decreases expression | ISO | RGD:1320210 | 6480464 | aristolochic acid I results in decreased expression of CORO2A mRNA | CTD | PMID:33212167 | arsenous acid | decreases expression | ISO | RGD:1320210 | 6480464 | Arsenic Trioxide results in decreased expression of CORO2A mRNA | CTD | PMID:26705709 | atrazine | increases expression | ISO | RGD:1320210 | 6480464 | Atrazine results in increased expression of CORO2A mRNA | CTD | PMID:22378314 | benzo[a]pyrene | decreases expression | ISO | RGD:1320210 | 6480464 | Benzo(a)pyrene results in decreased expression of CORO2A mRNA | CTD | PMID:22316170, PMID:26238291 | benzo[a]pyrene | increases methylation | ISO | RGD:1320210 | 6480464 | Benzo(a)pyrene results in increased methylation of CORO2A 5' UTR | CTD | PMID:27901495 | benzo[a]pyrene | multiple interactions | ISO | RGD:1320211 | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of CORO2A mRNA | CTD | PMID:27858113 | benzo[b]fluoranthene | multiple interactions | ISO | RGD:1320211 | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of CORO2A mRNA | CTD | PMID:27858113 | benzo[e]pyrene | increases methylation | ISO | RGD:1320210 | 6480464 | benzo(e)pyrene results in increased methylation of CORO2A intron | CTD | PMID:30157460 | bis(2-ethylhexyl) phthalate | increases expression | ISO | RGD:1320210 | 6480464 | Diethylhexyl Phthalate results in increased expression of CORO2A mRNA | CTD | PMID:31163220 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of CORO2A mRNA | CTD | PMID:25181051 | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of CORO2A gene | CTD | PMID:28505145 | cadmium dichloride | decreases methylation | EXP | | 6480464 | Cadmium Chloride results in decreased methylation of CORO2A promoter | CTD | PMID:22457795 | carbon nanotube | increases expression | ISO | RGD:1320211 | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | chlordecone | increases expression | ISO | RGD:1320211 | 6480464 | Chlordecone results in increased expression of CORO2A mRNA | CTD | PMID:33711761 | chloroprene | increases expression | ISO | RGD:1320211 | 6480464 | Chloroprene results in increased expression of CORO2A mRNA | CTD | PMID:23125180 | chrysene | multiple interactions | ISO | RGD:1320211 | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of CORO2A mRNA | CTD | PMID:27858113 | cisplatin | increases expression | ISO | RGD:1320210 | 6480464 | Cisplatin results in increased expression of CORO2A mRNA | CTD | PMID:27392435 | cisplatin | multiple interactions | ISO | RGD:1320210 | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of CORO2A mRNA | CTD | PMID:27392435 | copper atom | increases expression | EXP | | 6480464 | Copper deficiency results in increased expression of CORO2A mRNA | CTD | PMID:26033743 | copper(0) | increases expression | EXP | | 6480464 | Copper deficiency results in increased expression of CORO2A mRNA | CTD | PMID:26033743 | copper(II) sulfate | decreases expression | ISO | RGD:1320210 | 6480464 | Copper Sulfate results in decreased expression of CORO2A mRNA | CTD | PMID:19549813 | coumestrol | decreases expression | ISO | RGD:1320210 | 6480464 | Coumestrol results in decreased expression of CORO2A mRNA | CTD | PMID:19167446 | coumestrol | multiple interactions | ISO | RGD:1320210 | 6480464 | [Coumestrol co-treated with resveratrol] results in decreased expression of CORO2A mRNA | CTD | PMID:19167446 | cyclosporin A | decreases expression | ISO | RGD:1320210 | 6480464 | Cyclosporine results in decreased expression of CORO2A mRNA | CTD | PMID:25562108 | dexamethasone | multiple interactions | ISO | RGD:1320210 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of CORO2A mRNA | CTD | PMID:28628672 | diarsenic trioxide | decreases expression | ISO | RGD:1320210 | 6480464 | Arsenic Trioxide results in decreased expression of CORO2A mRNA | CTD | PMID:26705709 | dichloroacetic acid | decreases expression | ISO | RGD:1320211 | 6480464 | Dichloroacetic Acid results in decreased expression of CORO2A mRNA | CTD | PMID:28962523 | dioxygen | increases expression | ISO | RGD:1320210 | 6480464 | Oxygen deficiency results in increased expression of CORO2A mRNA | CTD | PMID:24236059 | dorsomorphin | multiple interactions | ISO | RGD:1320210 | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | endosulfan | affects expression | EXP | | 6480464 | Endosulfan affects the expression of CORO2A mRNA | CTD | PMID:29391264 | entinostat | multiple interactions | ISO | RGD:1320210 | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CORO2A mRNA | CTD | PMID:27188386 | entinostat | increases expression | ISO | RGD:1320210 | 6480464 | entinostat results in increased expression of CORO2A mRNA | CTD | PMID:26272509 | ethanol | affects splicing | ISO | RGD:1320211 | 6480464 | Ethanol affects the splicing of CORO2A mRNA | CTD | PMID:30319688 | folic acid | decreases expression | ISO | RGD:1320211 | 6480464 | Folic Acid results in decreased expression of CORO2A mRNA | CTD | PMID:25629700 | hydrogen peroxide | affects expression | ISO | RGD:1320210 | 6480464 | Hydrogen Peroxide affects the expression of CORO2A mRNA | CTD | PMID:20044591 | indometacin | multiple interactions | ISO | RGD:1320210 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of CORO2A mRNA | CTD | PMID:28628672 | lipopolysaccharide | multiple interactions | ISO | RGD:1320210 | 6480464 | [S-(1 more ... | CTD | PMID:35811015 | lipopolysaccharide | decreases expression | ISO | RGD:1320210 | 6480464 | Lipopolysaccharides results in decreased expression of CORO2A mRNA | CTD | PMID:35811015 | menadione | affects expression | ISO | RGD:1320210 | 6480464 | Vitamin K 3 affects the expression of CORO2A mRNA | CTD | PMID:20044591 | methapyrilene | increases methylation | ISO | RGD:1320210 | 6480464 | Methapyrilene results in increased methylation of CORO2A intron | CTD | PMID:30157460 | ozone | multiple interactions | ISO | RGD:1320211 | 6480464 | [Air Pollutants results in increased abundance of Ozone] which results in increased expression of CORO2A mRNA | CTD | PMID:34911549 | panobinostat | increases expression | ISO | RGD:1320210 | 6480464 | panobinostat results in increased expression of CORO2A mRNA | CTD | PMID:26272509 | panobinostat | multiple interactions | ISO | RGD:1320210 | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CORO2A mRNA | CTD | PMID:27188386 | PCB138 | multiple interactions | ISO | RGD:1320211 | 6480464 | [2 more ... | CTD | PMID:25510870 | phenobarbital | affects expression | ISO | RGD:1320210 | 6480464 | Phenobarbital affects the expression of CORO2A mRNA | CTD | PMID:19159669 | phenylmercury acetate | increases expression | ISO | RGD:1320210 | 6480464 | Phenylmercuric Acetate results in increased expression of CORO2A mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | ISO | RGD:1320210 | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CORO2A mRNA | CTD | PMID:27188386 | pirinixic acid | multiple interactions | ISO | RGD:1320210 | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of CORO2A mRNA | CTD | PMID:19710929 | pregnenolone 16alpha-carbonitrile | decreases expression | ISO | RGD:1320211 | 6480464 | Pregnenolone Carbonitrile results in decreased expression of CORO2A mRNA | CTD | PMID:28903501 | quercetin | decreases expression | ISO | RGD:1320210 | 6480464 | Quercetin results in decreased expression of CORO2A mRNA | CTD | PMID:21632981 | rac-lactic acid | decreases expression | ISO | RGD:1320210 | 6480464 | Lactic Acid results in decreased expression of CORO2A mRNA | CTD | PMID:30851411 | resveratrol | multiple interactions | ISO | RGD:1320210 | 6480464 | [Coumestrol co-treated with resveratrol] results in decreased expression of CORO2A mRNA | CTD | PMID:19167446 | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | RGD:1320210 | 6480464 | [S-(1 more ... | CTD | PMID:35811015 | SB 431542 | multiple interactions | ISO | RGD:1320210 | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | silicon dioxide | decreases expression | ISO | RGD:1320210 | 6480464 | Silicon Dioxide analog results in decreased expression of CORO2A mRNA | CTD | PMID:25895662 | temozolomide | increases expression | ISO | RGD:1320210 | 6480464 | Temozolomide results in increased expression of CORO2A mRNA | CTD | PMID:31758290 | tetraphene | multiple interactions | ISO | RGD:1320211 | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of CORO2A mRNA | CTD | PMID:27858113 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of CORO2A mRNA | CTD | PMID:23411599 | tributylstannane | increases expression | ISO | RGD:1320211 | 6480464 | tributyltin results in increased expression of CORO2A mRNA | CTD | PMID:31939706 | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of CORO2A mRNA | CTD | PMID:33387578 | trichostatin A | increases expression | ISO | RGD:1320210 | 6480464 | trichostatin A results in increased expression of CORO2A mRNA | CTD | PMID:24935251, PMID:26272509 | trichostatin A | multiple interactions | ISO | RGD:1320210 | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CORO2A mRNA | CTD | PMID:27188386 | trimellitic anhydride | increases expression | ISO | RGD:1320211 | 6480464 | trimellitic anhydride results in increased expression of CORO2A mRNA | CTD | PMID:19042947 | tungsten | decreases expression | ISO | RGD:1320211 | 6480464 | Tungsten results in decreased expression of CORO2A mRNA | CTD | PMID:30912803 | valproic acid | increases methylation | ISO | RGD:1320210 | 6480464 | Valproic Acid results in increased methylation of CORO2A gene | CTD | PMID:29154799 | valproic acid | affects expression | ISO | RGD:1320210 | 6480464 | Valproic Acid affects the expression of CORO2A mRNA | CTD | PMID:25979313 | valproic acid | increases expression | ISO | RGD:1320210 | 6480464 | Valproic Acid results in increased expression of CORO2A mRNA | CTD | PMID:19101580 more ... | valproic acid | multiple interactions | ISO | RGD:1320210 | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CORO2A mRNA | CTD | PMID:27188386 | vinclozolin | increases methylation | EXP | | 6480464 | vinclozolin results in increased methylation of CORO2A gene | CTD | PMID:31079544 | vorinostat | increases expression | ISO | RGD:1320210 | 6480464 | vorinostat results in increased expression of CORO2A mRNA | CTD | PMID:26272509 | vorinostat | multiple interactions | ISO | RGD:1320210 | 6480464 | [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CORO2A mRNA | CTD | PMID:27188386 | |