Tmod1 (tropomodulin 1) - Rat Genome Database

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Gene: Tmod1 (tropomodulin 1) Rattus norvegicus
Analyze
Symbol: Tmod1
Name: tropomodulin 1
RGD ID: 3874
Description: Enables tropomyosin binding activity. Predicted to be involved in actin cytoskeleton organization; lens fiber cell development; and muscle contraction. Predicted to act upstream of or within adult locomotory behavior. Located in cytoplasm and nucleus. Orthologous to human TMOD1 (tropomodulin 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: E-Tmod; E-Tropomodulin; erythrocyte tropomodulin; Tmod; tropomodulin-1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2560,316,445 - 60,393,957 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl560,338,512 - 60,393,956 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx562,288,970 - 62,366,361 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0564,108,477 - 64,185,864 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0564,077,726 - 64,155,120 (+)NCBIRnor_WKY
Rnor_6.0561,635,244 - 61,712,052 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl561,657,507 - 61,712,051 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0566,151,206 - 66,228,500 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4562,578,142 - 62,668,760 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1562,578,320 - 62,668,938 (+)NCBI
Celera558,878,456 - 58,954,722 (+)NCBICelera
Cytogenetic Map5q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dichloroethane  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-butoxyethanol  (ISO)
2-methylcholine  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
6-propyl-2-thiouracil  (EXP)
8-Br-cAMP  (ISO)
acrylamide  (EXP)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
astemizole  (EXP)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (ISO)
bisphenol F  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
cisplatin  (EXP)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
cypermethrin  (ISO)
dibutyl phthalate  (EXP)
dioxygen  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
ethanol  (ISO)
fulvestrant  (ISO)
genistein  (ISO)
graphite  (EXP)
lead nitrate  (EXP)
methapyrilene  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
nickel sulfate  (ISO)
nitrofen  (EXP)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
pioglitazone  (ISO)
pirinixic acid  (EXP,ISO)
progesterone  (EXP,ISO)
raloxifene  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (EXP,ISO)
sodium fluoride  (ISO)
sulforaphane  (ISO)
tamoxifen  (ISO)
Tesaglitazar  (EXP)
topotecan  (EXP)
tremolite asbestos  (ISO)
tributylstannane  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
troglitazone  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
actin filament  (ISO,ISS)
COP9 signalosome  (ISO)
cortical cytoskeleton  (ISO)
cytoplasm  (IDA)
cytoskeleton  (IBA,IEA)
membrane  (ISO)
myofibril  (IBA,ISO,ISS)
nucleus  (IDA)
sarcomere  (ISO,ISS)
striated muscle thin filament  (IBA,ISO)

Molecular Function
actin binding  (ISO,ISS)
actin filament binding  (IEA)
tropomyosin binding  (IBA,IDA,IEA,ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Cytoplasmic nuclear transfer of the actin-capping protein tropomodulin. Kong KY and Kedes L, J Biol Chem. 2004 Jul 16;279(29):30856-64. Epub 2004 Apr 29.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
9. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
10. N-tropomodulin: a novel isoform of tropomodulin identified as the major binding protein to brain tropomyosin. Watakabe A, etal., J Cell Sci 1996 Sep;109 ( Pt 9)(2):2299-310.
Additional References at PubMed
PMID:14657235   PMID:14741341   PMID:18723693   PMID:18850735   PMID:20368620   PMID:20685966   PMID:21078668   PMID:23144950   PMID:24840128   PMID:25250574   PMID:26370058   PMID:27126680  
PMID:30301754  


Genomics

Comparative Map Data
Tmod1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2560,316,445 - 60,393,957 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl560,338,512 - 60,393,956 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx562,288,970 - 62,366,361 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0564,108,477 - 64,185,864 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0564,077,726 - 64,155,120 (+)NCBIRnor_WKY
Rnor_6.0561,635,244 - 61,712,052 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl561,657,507 - 61,712,051 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0566,151,206 - 66,228,500 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4562,578,142 - 62,668,760 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1562,578,320 - 62,668,938 (+)NCBI
Celera558,878,456 - 58,954,722 (+)NCBICelera
Cytogenetic Map5q22NCBI
TMOD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38997,501,180 - 97,601,743 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl997,501,180 - 97,601,743 (+)EnsemblGRCh38hg38GRCh38
GRCh379100,263,462 - 100,364,025 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36999,326,258 - 99,403,351 (+)NCBINCBI36Build 36hg18NCBI36
Celera970,777,697 - 70,878,281 (+)NCBICelera
Cytogenetic Map9q22.33NCBI
HuRef969,864,624 - 69,965,202 (+)NCBIHuRef
CHM1_19100,409,900 - 100,510,457 (+)NCBICHM1_1
T2T-CHM13v2.09109,673,130 - 109,773,684 (+)NCBIT2T-CHM13v2.0
Tmod1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39446,038,940 - 46,116,032 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl446,038,935 - 46,116,032 (+)EnsemblGRCm39 Ensembl
GRCm38446,038,940 - 46,116,032 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl446,038,935 - 46,116,032 (+)EnsemblGRCm38mm10GRCm38
MGSCv37446,052,094 - 46,128,904 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36446,082,066 - 46,135,896 (+)NCBIMGSCv36mm8
Celera446,061,367 - 46,138,280 (+)NCBICelera
Cytogenetic Map4B1NCBI
cM Map424.49NCBI
Tmod1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541927,841,424 - 27,915,540 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541927,841,424 - 27,915,540 (-)NCBIChiLan1.0ChiLan1.0
TMOD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1996,714,237 - 96,813,936 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl996,714,237 - 96,813,936 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0968,592,195 - 68,692,001 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
TMOD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11154,853,205 - 54,914,236 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1154,853,204 - 54,912,773 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1153,267,257 - 53,348,437 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01155,945,577 - 56,026,805 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1155,945,563 - 56,026,799 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11154,441,999 - 54,523,177 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01154,471,825 - 54,553,034 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01155,168,518 - 55,249,717 (+)NCBIUU_Cfam_GSD_1.0
Tmod1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947169,778,850 - 169,856,410 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365246,326,400 - 6,403,057 (+)EnsemblSpeTri2.0
SpeTri2.0NW_0049365246,347,089 - 6,403,996 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NCBP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1239,396,097 - 239,467,758 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11239,375,150 - 239,468,387 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21267,547,207 - 267,646,850 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TMOD1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11241,808,594 - 41,899,713 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1241,811,036 - 41,877,357 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603838,861,593 - 38,953,232 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tmod1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248253,228,305 - 3,299,799 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248253,229,095 - 3,299,709 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tmod1
394 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:424
Count of miRNA genes:223
Interacting mature miRNAs:285
Transcripts:ENSRNOT00000013228
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)5190450412Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51131345958Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)572947086724018Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
8662454Vetf3Vascular elastic tissue fragility QTL 327.4artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)5228222669540447Rat
7394712Emca13Estrogen-induced mammary cancer QTL 13mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)5982326699753708Rat
634305Mamtr1Mammary tumor resistance QTL 10.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)512789751113558310Rat
1600358Mamtr5Mammary tumor resistance QTL 5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)51887394763873947Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)51887394774251464Rat
8552954Pigfal14Plasma insulin-like growth factor 1 level QTL 149blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)52122674466226744Rat
1578767Stresp17Stress response QTL 174.30.01blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)52795544072955440Rat
1578776Stresp18Stress response QTL 182.9thymus mass (VT:0004954)thymus wet weight (CMO:0000855)52795544072955440Rat
6903292Stl28Serum triglyceride level QTL 282.60.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)52851548973515489Rat
6903306Scl35Serum cholesterol QTL 352.60.0073blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)52851548973515489Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)531663789131345958Rat
1598807Glom12Glomerulus QTL 122.7kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)53321566578215665Rat
1298067Scl15Serum cholesterol level QTL 154.80.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53321566578215665Rat
1302786Kidm8Kidney mass QTL 828.15kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)53321566578215665Rat
1576317Eutr2Estrogen induced uterine response QTL 20.01uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)534730116104251008Rat
2316959Gluco59Glucose level QTL 594.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)534944474113558310Rat
1641922Alcrsp8Alcohol response QTL 8alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)53518915368564008Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)535189153141643988Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
1331773Scl26Serum cholesterol level QTL 263.065blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)54372665686724018Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)543726656129132602Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
1300115Hrtrt7Heart rate QTL 72.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)54786906290099692Rat
9589025Epfw7Epididymal fat weight QTL 720.660.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)54946360094463600Rat
7411561Bw134Body weight QTL 134240.001body mass (VT:0001259)body weight gain (CMO:0000420)54946360094463600Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)550328551141643988Rat
2303615Vencon7Ventilatory control QTL 70.001respiration trait (VT:0001943)respiration rate (CMO:0000289)55098389595983895Rat
2303574Gluco42Glucose level QTL 422blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)55349671998496719Rat
61359EaexExperimental allergic encephalomyelitis QTL x3nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)555715622100715622Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555805606132207589Rat
1358895Bp254Blood pressure QTL 2543.60.0003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)558829236128034027Rat
61426Scl2Serum cholesterol level QTL 27.30.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)559793399143070159Rat
2316954Rf57Renal function QTL 570kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)55979352890450144Rat
2316957Pur21Proteinuria QTL 216.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)559793528113558156Rat
61386Bp49Blood pressure QTL 4916.6cerebrum integrity trait (VT:0010549)brain infarction volume (CMO:0001013)56029343498603051Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)560293434161481680Rat

Markers in Region
D5Mco30  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2560,333,977 - 60,334,226 (+)MAPPERmRatBN7.2
Rnor_6.0561,652,973 - 61,653,221NCBIRnor6.0
Rnor_5.0566,168,872 - 66,169,120UniSTSRnor5.0
RGSC_v3.4562,594,554 - 62,594,802RGDRGSC3.4
RGSC_v3.4562,594,555 - 62,594,803UniSTSRGSC3.4
RGSC_v3.1562,594,733 - 62,594,981RGD
Celera558,895,847 - 58,896,095UniSTS
Cytogenetic Map5q22UniSTS
BE102142  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2560,338,513 - 60,338,671 (+)MAPPERmRatBN7.2
Rnor_6.0561,657,509 - 61,657,666NCBIRnor6.0
Rnor_5.0566,173,408 - 66,173,565UniSTSRnor5.0
RGSC_v3.4562,599,091 - 62,599,248UniSTSRGSC3.4
Celera558,900,383 - 58,900,540UniSTS
RH 3.4 Map5379.7UniSTS
Cytogenetic Map5q22UniSTS
RH129174  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2560,393,009 - 60,393,229 (+)MAPPERmRatBN7.2
Rnor_6.0561,711,105 - 61,711,324NCBIRnor6.0
Rnor_5.0566,227,553 - 66,227,772UniSTSRnor5.0
RGSC_v3.4562,667,813 - 62,668,032UniSTSRGSC3.4
Celera558,953,775 - 58,953,994UniSTS
Cytogenetic Map5q22UniSTS
BE101076  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2560,338,525 - 60,338,671 (+)MAPPERmRatBN7.2
Rnor_6.0561,657,521 - 61,657,666NCBIRnor6.0
Rnor_5.0566,173,420 - 66,173,565UniSTSRnor5.0
RGSC_v3.4562,599,103 - 62,599,248UniSTSRGSC3.4
Celera558,900,395 - 58,900,540UniSTS
RH 3.4 Map5376.2UniSTS
Cytogenetic Map5q22UniSTS
AU048374  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2560,371,967 - 60,372,125 (+)MAPPERmRatBN7.2
Rnor_6.0561,690,957 - 61,691,114NCBIRnor6.0
Rnor_5.0566,207,085 - 66,207,242UniSTSRnor5.0
RGSC_v3.4562,632,540 - 62,632,697UniSTSRGSC3.4
Celera558,933,724 - 58,933,881UniSTS
Cytogenetic Map5q22UniSTS
BF391929  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2560,364,653 - 60,364,834 (+)MAPPERmRatBN7.2
Rnor_6.0561,683,645 - 61,683,825NCBIRnor6.0
Rnor_5.0566,199,773 - 66,199,953UniSTSRnor5.0
RGSC_v3.4562,625,228 - 62,625,408UniSTSRGSC3.4
Celera558,926,412 - 58,926,592UniSTS
RH 3.4 Map5717.0UniSTS
Cytogenetic Map5q22UniSTS
BM383810  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2560,378,356 - 60,378,561 (+)MAPPERmRatBN7.2
Rnor_6.0561,697,344 - 61,697,548NCBIRnor6.0
Rnor_5.0566,213,472 - 66,213,676UniSTSRnor5.0
RGSC_v3.4562,638,927 - 62,639,131UniSTSRGSC3.4
Celera558,940,111 - 58,940,315UniSTS
RH 3.4 Map5392.3UniSTS
Cytogenetic Map5q22UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 43 16 16 6 16 8 11 22 16 11 8
Low 3 37 21 13 21 50 35 25
Below cutoff 4 4 4 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000013228   ⟹   ENSRNOP00000013228
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl560,338,512 - 60,393,956 (+)Ensembl
Rnor_6.0 Ensembl561,657,507 - 61,712,051 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000109364   ⟹   ENSRNOP00000076573
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl560,338,512 - 60,387,529 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000113823   ⟹   ENSRNOP00000077344
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl560,342,669 - 60,393,956 (+)Ensembl
RefSeq Acc Id: NM_013044   ⟹   NP_037176
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2560,316,445 - 60,393,957 (+)NCBI
Rnor_6.0561,635,611 - 61,712,052 (+)NCBI
Rnor_5.0566,151,206 - 66,228,500 (+)NCBI
RGSC_v3.4562,578,142 - 62,668,760 (+)RGD
Celera558,878,456 - 58,954,722 (+)RGD
Sequence:
RefSeq Acc Id: XM_039109313   ⟹   XP_038965241
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2560,342,737 - 60,393,953 (+)NCBI
RefSeq Acc Id: XM_039109314   ⟹   XP_038965242
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2560,339,470 - 60,393,953 (+)NCBI
RefSeq Acc Id: XM_039109315   ⟹   XP_038965243
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2560,339,491 - 60,393,953 (+)NCBI
RefSeq Acc Id: XM_039109316   ⟹   XP_038965244
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2560,316,447 - 60,393,953 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_037176   ⟸   NM_013044
- UniProtKB: Q6IMZ5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000013228   ⟸   ENSRNOT00000013228
RefSeq Acc Id: XP_038965244   ⟸   XM_039109316
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038965242   ⟸   XM_039109314
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038965243   ⟸   XM_039109315
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038965241   ⟸   XM_039109313
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZKA1 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000077344   ⟸   ENSRNOT00000113823
RefSeq Acc Id: ENSRNOP00000076573   ⟸   ENSRNOT00000109364

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P70567-F1-model_v2 AlphaFold P70567 1-359 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3874 AgrOrtholog
BioCyc Gene G2FUF-41417 BioCyc
Ensembl Genes ENSRNOG00000009761 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000013228 ENTREZGENE
  ENSRNOP00000013228.3 UniProtKB/TrEMBL
  ENSRNOP00000076573.1 UniProtKB/TrEMBL
  ENSRNOP00000077344 ENTREZGENE
  ENSRNOP00000077344.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000013228 ENTREZGENE
  ENSRNOT00000013228.5 UniProtKB/TrEMBL
  ENSRNOT00000109364.1 UniProtKB/TrEMBL
  ENSRNOT00000113823 ENTREZGENE
  ENSRNOT00000113823.1 UniProtKB/TrEMBL
Gene3D-CATH 3.80.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7105834 IMAGE-MGC_LOAD
InterPro LRR_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TMOD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TMOD1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:25566 UniProtKB/TrEMBL
MGC_CLONE MGC:91767 IMAGE-MGC_LOAD
NCBI Gene 25566 ENTREZGENE
PANTHER PTHR10901 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10901:SF8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Tropomodulin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Tmod1 PhenoGen
TIGR TC228630
UniProt A0A8I5YBE0_RAT UniProtKB/TrEMBL
  A0A8I5ZKA1 ENTREZGENE, UniProtKB/TrEMBL
  P70567 ENTREZGENE
  Q6IMZ5 ENTREZGENE, UniProtKB/TrEMBL
  TMOD1_RAT UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2003-04-09 Tmod1  tropomodulin 1  Tmod  E-Tropomodulin  Symbol and Name updated 629477 APPROVED
2002-06-10 Tmod  E-Tropomodulin      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression mainly expressed in neurons of the brain 61770