Symbol:
Frrs1l
Name:
ferric-chelate reductase 1-like
RGD ID:
1309978
Description:
Predicted to enable dynein intermediate chain binding activity. Involved in regulation of postsynaptic membrane neurotransmitter receptor levels. Predicted to be located in plasma membrane. Predicted to be active in endoplasmic reticulum membrane and postsynapse. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 37. Orthologous to human FRRS1L (ferric chelate reductase 1 like); INTERACTS WITH 17alpha-ethynylestradiol; 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
DOMON domain-containing protein FRRS1L; Epb4.1l4b; erythrocyte protein band 4.1-like 4b; ferric-chelate reductase 1-like protein; LOC366376
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 5 76,451,101 - 76,485,319 (-) NCBI GRCr8 mRatBN7.2 5 71,655,911 - 71,690,132 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 5 71,659,284 - 71,690,108 (-) Ensembl mRatBN7.2 Ensembl Rnor_6.0 5 73,997,958 - 74,029,381 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 5 74,000,227 - 74,029,238 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 5 78,152,377 - 78,183,855 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 5 74,866,398 - 74,896,487 (-) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 5 74,871,510 - 74,954,497 (-) NCBI Celera 5 70,513,180 - 70,544,038 (-) NCBI Celera Cytogenetic Map 5 q24 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Frrs1l Rat choreatic disease ISO RGD:1346527 8554872 ClinVar Annotator: match by term: Choreatic disease ClinVar PMID:23056405|PMID:25741868|PMID:27236917|PMID:28492532|PMID:32928027 Frrs1l Rat developmental and epileptic encephalopathy 37 ISO RGD:1346527 8554872 ClinVar Annotator: match by term: Developmental and epileptic encephalopathy, 37 | ClinVar Annotator: match by more ... ClinVar PMID:16199547|PMID:17576681|PMID:19763152|PMID:20307669|PMID:21147040|PMID:22406018|PMID:23056405|PMID:25741868|PMID:27236917|PMID:27239025|PMID:28492532|PMID:28675162|PMID:30525197|PMID:30692144|PMID:32860008|PMID:32928027|PMID:9536098 Frrs1l Rat epilepsy ISO RGD:1346527 8554872 ClinVar Annotator: match by term: Seizure ClinVar PMID:21147040|PMID:23056405|PMID:25741868|PMID:27236917|PMID:27239025|PMID:28492532|PMID:32860008|PMID:32928027 Frrs1l Rat genetic disease ISO RGD:1346527 8554872 ClinVar Annotator: match by term: Inborn genetic diseases ClinVar PMID:23056405|PMID:25741868|PMID:27236917|PMID:28492532|PMID:32928027
Frrs1l (Rattus norvegicus - Norway rat)
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 5 76,451,101 - 76,485,319 (-) NCBI GRCr8 mRatBN7.2 5 71,655,911 - 71,690,132 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 5 71,659,284 - 71,690,108 (-) Ensembl mRatBN7.2 Ensembl Rnor_6.0 5 73,997,958 - 74,029,381 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 5 74,000,227 - 74,029,238 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 5 78,152,377 - 78,183,855 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 5 74,866,398 - 74,896,487 (-) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 5 74,871,510 - 74,954,497 (-) NCBI Celera 5 70,513,180 - 70,544,038 (-) NCBI Celera Cytogenetic Map 5 q24 NCBI
FRRS1L (Homo sapiens - human)
Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 9 109,130,293 - 109,167,249 (-) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 9 109,130,293 - 109,167,249 (-) Ensembl GRCh38 hg38 GRCh38 GRCh37 9 111,892,573 - 111,929,529 (-) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 9 110,939,402 - 110,969,392 (-) NCBI NCBI36 Build 36 hg18 NCBI36 Celera 9 82,398,790 - 82,428,780 (-) NCBI Celera Cytogenetic Map 9 q31.3 NCBI HuRef 9 81,499,489 - 81,529,700 (-) NCBI HuRef CHM1_1 9 112,046,053 - 112,076,070 (-) NCBI CHM1_1 T2T-CHM13v2.0 9 121,299,358 - 121,336,331 (-) NCBI T2T-CHM13v2.0
Frrs1l (Mus musculus - house mouse)
Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 4 56,957,173 - 56,990,408 (-) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 4 56,957,173 - 56,990,391 (-) Ensembl GRCm39 Ensembl GRCm38 4 56,960,136 - 56,990,391 (-) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 4 56,957,173 - 56,990,391 (-) Ensembl GRCm38 mm10 GRCm38 MGSCv37 4 56,973,008 - 57,003,263 (-) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 4 57,056,871 - 57,084,564 (-) NCBI MGSCv36 mm8 Celera 4 56,869,139 - 56,900,419 (-) NCBI Celera Cytogenetic Map 4 B3 NCBI cM Map 4 31.66 NCBI
Frrs1l (Chinchilla lanigera - long-tailed chinchilla)
Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955419 17,825,868 - 17,848,868 (+) Ensembl ChiLan1.0 ChiLan1.0 NW_004955419 17,825,868 - 17,848,868 (+) NCBI ChiLan1.0 ChiLan1.0
FRRS1L (Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 11 30,240,491 - 30,277,394 (+) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 9 30,242,858 - 30,279,759 (+) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 9 80,283,385 - 80,320,293 (-) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 9 108,462,269 - 108,491,968 (-) NCBI panpan1.1 PanPan1.1 panPan2
FRRS1L (Canis lupus familiaris - dog)
Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 11 64,281,466 - 64,298,319 (-) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl 11 64,281,892 - 64,292,418 (-) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 11 62,682,468 - 62,706,912 (-) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 11 65,415,181 - 65,439,701 (-) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl 11 65,409,937 - 65,439,686 (-) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 11 63,934,536 - 63,958,849 (-) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 11 63,956,494 - 63,981,023 (-) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 11 64,647,321 - 64,671,674 (-) NCBI UU_Cfam_GSD_1.0
Frrs1l (Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl HiC_Itri_2 NW_024404947 179,514,818 - 179,543,255 (-) NCBI HiC_Itri_2 SpeTri2.0 Ensembl NW_004936559 3,722,890 - 3,750,919 (+) Ensembl SpeTri2.0 SpeTri2.0 Ensembl SpeTri2.0 NW_004936559 3,723,325 - 3,753,209 (+) NCBI SpeTri2.0 SpeTri2.0 SpeTri2.0
FRRS1L (Sus scrofa - pig)
Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl 1 250,194,230 - 250,220,716 (-) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 1 250,187,568 - 250,220,716 (-) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 1 280,723,135 - 280,750,355 (-) NCBI Sscrofa10.2 Sscrofa10.2 susScr3
FRRS1L (Chlorocebus sabaeus - green monkey)
Green Monkey Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChlSab1.1 12 30,385,877 - 30,416,302 (+) NCBI ChlSab1.1 ChlSab1.1 chlSab2 ChlSab1.1 Ensembl 12 30,385,878 - 30,416,088 (+) Ensembl ChlSab1.1 ChlSab1.1 Ensembl chlSab2 Vero_WHO_p1.0 NW_023666035 12,268,035 - 12,298,514 (-) NCBI Vero_WHO_p1.0 Vero_WHO_p1.0
Frrs1l (Heterocephalus glaber - naked mole-rat)
.
Predicted Target Of
Count of predictions: 119 Count of miRNA genes: 95 Interacting mature miRNAs: 101 Transcripts: ENSRNOT00000031432 Prediction methods: Microtar, Miranda, Rnahybrid, Targetscan Result types: miRGate_prediction
1578776 Stresp18 Stress response QTL 18 2.9 thymus mass (VT:0004954) thymus wet weight (CMO:0000855) 5 27955440 72955440 Rat 1298067 Scl15 Serum cholesterol level QTL 15 4.8 0.001 blood cholesterol amount (VT:0000180) plasma total cholesterol level (CMO:0000585) 5 33215665 78215665 Rat 1300115 Hrtrt7 Heart rate QTL 7 2.76 heart pumping trait (VT:2000009) heart rate (CMO:0000002) 5 47869062 90099692 Rat 1357396 Bw44 Body weight QTL 44 4.19 body mass (VT:0001259) body weight (CMO:0000012) 5 68984307 104251008 Rat 1549845 Scl44 Serum cholesterol level QTL 44 6 blood cholesterol amount (VT:0000180) serum total cholesterol level (CMO:0000363) 5 40128307 148607290 Rat 61380 Edpm5 Estrogen-dependent pituitary mass QTL 5 4.5 0.92 pituitary gland mass (VT:0010496) pituitary gland wet weight (CMO:0000853) 5 68984307 104251008 Rat 70212 Niddm25 Non-insulin dependent diabetes mellitus QTL 25 3.54 blood glucose amount (VT:0000188) blood glucose level (CMO:0000046) 5 1 131345958 Rat 1358353 Srcrtb2 Stress Responsive Cort Basal QTL 2 3.48 0.003 blood corticosterone amount (VT:0005345) plasma corticosterone level (CMO:0001173) 5 18873947 74251464 Rat 634305 Mamtr1 Mammary tumor resistance QTL 1 0.0001 mammary gland integrity trait (VT:0010552) mammary tumor number (CMO:0000343) 5 12789751 113558310 Rat 61386 Bp49 Blood pressure QTL 49 16.6 cerebrum integrity trait (VT:0010549) brain infarction volume (CMO:0001013) 5 60293434 98603051 Rat 1331801 Rf33 Renal function QTL 33 4.149 kidney blood vessel physiology trait (VT:0100012) absolute change in renal vascular resistance (CMO:0001900) 5 43726656 129132602 Rat 1357402 Bw46 Body weight QTL 46 4.47 body mass (VT:0001259) body mass index (BMI) (CMO:0000105) 5 68984307 104251008 Rat 2302381 Bw84 Body weight QTL 84 4.47 body mass (VT:0001259) body mass index (BMI) (CMO:0000105) 5 68984307 104251008 Rat 1598807 Glom12 Glomerulus QTL 12 2.7 kidney glomerulus morphology trait (VT:0005325) index of glomerular damage (CMO:0001135) 5 33215665 78215665 Rat 1302786 Kidm8 Kidney mass QTL 8 28.15 kidney mass (VT:0002707) both kidneys wet weight to body weight ratio (CMO:0000340) 5 33215665 78215665 Rat 61393 Bp7 Blood pressure QTL 7 4.5 0.0001 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 5 60293434 161481680 Rat 6903292 Stl28 Serum triglyceride level QTL 28 2.6 0.0073 blood triglyceride amount (VT:0002644) plasma triglyceride level (CMO:0000548) 5 28515489 73515489 Rat 1578766 Tcas11 Tongue tumor susceptibility QTL 11 4.12 tongue integrity trait (VT:0010553) number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950) 5 46711509 161317411 Rat 1578767 Stresp17 Stress response QTL 17 4.3 0.01 blood aldosterone amount (VT:0005346) plasma aldosterone level (CMO:0000551) 5 27955440 72955440 Rat 7411561 Bw134 Body weight QTL 134 24 0.001 body mass (VT:0001259) body weight gain (CMO:0000420) 5 49463600 94463600 Rat 2303615 Vencon7 Ventilatory control QTL 7 0.001 respiration trait (VT:0001943) respiration rate (CMO:0000289) 5 50983895 95983895 Rat 1576312 Emca8 Estrogen-induced mammary cancer QTL 8 4.1 mammary gland integrity trait (VT:0010552) mammary tumor number (CMO:0000343) 5 50328551 141643988 Rat 1641912 Alcrsp18 Alcohol response QTL 18 response to alcohol trait (VT:0010489) duration of loss of righting reflex (CMO:0002289) 5 35189153 141643988 Rat 1576314 Eutr1 Estrogen induced uterine response QTL 1 uterus integrity trait (VT:0010575) pyometritis severity score (CMO:0002009) 5 2138965 166875058 Rat 6903306 Scl35 Serum cholesterol QTL 35 2.6 0.0073 blood cholesterol amount (VT:0000180) plasma total cholesterol level (CMO:0000585) 5 28515489 73515489 Rat 1576317 Eutr2 Estrogen induced uterine response QTL 2 0.01 uterus integrity trait (VT:0010575) pyometritis severity score (CMO:0002009) 5 34730116 104251008 Rat 7394712 Emca13 Estrogen-induced mammary cancer QTL 13 mammary gland integrity trait (VT:0010552) mammary tumor number (CMO:0000343) 5 9823266 99753708 Rat 1331773 Scl26 Serum cholesterol level QTL 26 3.065 blood cholesterol amount (VT:0000180) serum total cholesterol level (CMO:0000363) 5 43726656 86724018 Rat 70189 Mcs5 Mammary carcinoma susceptibility QTL 5 10.51 mammary gland integrity trait (VT:0010552) mammary tumor number (CMO:0000343) 5 55805606 132207589 Rat 1331771 Rf35 Renal function QTL 35 4.36965 kidney blood vessel physiology trait (VT:0100012) absolute change in renal blood flow rate (CMO:0001168) 5 729470 86724018 Rat 61359 Eaex Experimental allergic encephalomyelitis QTL x 3 nervous system integrity trait (VT:0010566) post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422) 5 55715622 100715622 Rat 2290448 Scl54 Serum cholesterol level QTL 54 2.93 blood cholesterol amount (VT:0000180) plasma total cholesterol level (CMO:0000585) 5 31663789 131345958 Rat 61426 Scl2 Serum cholesterol level QTL 2 7.3 0.001 blood cholesterol amount (VT:0000180) serum total cholesterol level (CMO:0000363) 5 59793399 143070159 Rat 1354598 Srn6 Serum renin concentration QTL 6 3.8 blood renin amount (VT:0003349) plasma renin activity level (CMO:0000116) 5 69540295 151018848 Rat 9589025 Epfw7 Epididymal fat weight QTL 7 20.66 0.001 epididymal fat pad mass (VT:0010421) epididymal fat pad weight to body weight ratio (CMO:0000658) 5 49463600 94463600 Rat 2303574 Gluco42 Glucose level QTL 42 2 blood glucose amount (VT:0000188) blood glucose level (CMO:0000046) 5 53496719 98496719 Rat 2290005 Mcs24 Mammary carcinoma susceptibility QTL 24 mammary gland integrity trait (VT:0010552) mammary tumor number (CMO:0000343) 5 64719390 109719390 Rat 1331756 Rf34 Renal function QTL 34 4.16275 kidney blood vessel physiology trait (VT:0100012) absolute change in renal blood flow rate (CMO:0001168) 5 1 90450412 Rat 2306971 Anxrr21 Anxiety related response QTL 21 9.47 fear/anxiety-related behavior trait (VT:1000241) number of entries into a discrete space in an experimental apparatus (CMO:0000960) 5 66174080 124160948 Rat 2316954 Rf57 Renal function QTL 57 0 kidney glomerulus morphology trait (VT:0005325) index of glomerular damage (CMO:0001135) 5 59793528 90450144 Rat 1358895 Bp254 Blood pressure QTL 254 3.6 0.0003 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 5 58829236 128034027 Rat 2316959 Gluco59 Glucose level QTL 59 4.7 blood glucose amount (VT:0000188) blood glucose level (CMO:0000046) 5 34944474 113558310 Rat 2312671 Scl64 Serum cholesterol level QTL 64 0.001 blood cholesterol amount (VT:0000180) serum total cholesterol level (CMO:0000363) 5 68984307 104251008 Rat 2316957 Pur21 Proteinuria QTL 21 6.2 urine protein amount (VT:0005160) urine protein level (CMO:0000591) 5 59793528 113558156 Rat
RH133118
Rat Assembly Chr Position (strand) Source JBrowse GRCr8 5 76,487,088 - 76,487,284 (+) Marker Load Pipeline mRatBN7.2 5 71,691,903 - 71,692,099 (+) MAPPER mRatBN7.2 Rnor_6.0 5 74,031,148 - 74,031,343 NCBI Rnor6.0 Rnor_5.0 5 78,185,468 - 78,185,663 UniSTS Rnor5.0 RGSC_v3.4 5 74,898,254 - 74,898,449 UniSTS RGSC3.4 Celera 5 70,545,489 - 70,545,684 UniSTS RH 3.4 Map 5 484.8 UniSTS Cytogenetic Map 5 q24 UniSTS
RH134760
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 5 71,692,456 - 71,692,638 (+) MAPPER mRatBN7.2 Rnor_6.0 5 74,031,701 - 74,031,882 NCBI Rnor6.0 Rnor_5.0 5 78,186,021 - 78,186,202 UniSTS Rnor5.0 RGSC_v3.4 5 74,898,807 - 74,898,988 UniSTS RGSC3.4 Celera 5 70,546,042 - 70,546,223 UniSTS RH 3.4 Map 5 484.8 UniSTS Cytogenetic Map 5 q24 UniSTS
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
alimentary part of gastrointestinal system
9
10
49
110
69
68
41
24
41
3
196
93
93
45
55
27
Too many to show, limit is 500. Download them if you would like to view them all.
Ensembl Acc Id:
ENSRNOT00000031432 ⟹ ENSRNOP00000031856
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 5 71,659,284 - 71,690,108 (-) Ensembl Rnor_6.0 Ensembl 5 74,000,227 - 74,029,238 (-) Ensembl
RefSeq Acc Id:
NM_001419637 ⟹ NP_001406566
RefSeq Status:
VALIDATED
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 5 76,451,101 - 76,485,316 (-) NCBI mRatBN7.2 5 71,655,911 - 71,690,131 (-) NCBI
RefSeq Acc Id:
XM_039111411 ⟹ XP_038967339
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 5 76,451,101 - 76,485,319 (-) NCBI mRatBN7.2 5 71,661,551 - 71,690,132 (-) NCBI
Ensembl Acc Id:
ENSRNOP00000031856 ⟸ ENSRNOT00000031432
RefSeq Acc Id:
XP_038967339 ⟸ XM_039111411
- Peptide Label:
isoform X1
RefSeq Acc Id:
NP_001406566 ⟸ NM_001419637
- Peptide Label:
precursor
- UniProtKB:
D3ZE85 (UniProtKB/Swiss-Prot)
Date
Current Symbol
Current Name
Previous Symbol
Previous Name
Description
Reference
Status
2012-07-16
Frrs1l
ferric-chelate reductase 1-like
Epb4.1l4b
erythrocyte protein band 4.1-like 4b
Nomenclature updated to reflect human and mouse nomenclature
1299863
APPROVED
2008-04-30
Epb4.1l4b
erythrocyte protein band 4.1-like 4b
Epb4.1l4b_predicted
erythrocyte protein band 4.1-like 4b (predicted)
'predicted' is removed
2292626
APPROVED
2008-01-09
Epb4.1l4b_predicted
erythrocyte protein band 4.1-like 4b (predicted)
LOC682088
similar to CG8399-PA
Data merged from RGD:1588080
1643240
APPROVED
2006-11-19
LOC682088
similar to CG8399-PA
Symbol and Name status set to provisional
70820
PROVISIONAL
2005-01-12
Epb4.1l4b_predicted
erythrocyte protein band 4.1-like 4b (predicted)
Symbol and Name status set to approved
70820
APPROVED