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Gene: Rnf38 (ring finger protein 38) Rattus norvegicus
Analyze
Symbol:
Rnf38
Name:
ring finger protein 38
RGD ID:
621856
Description:
Predicted to have ubiquitin protein ligase activity. Involved in male gonad development. Localizes to sperm flagellum. Orthologous to human RNF38 (ring finger protein 38); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; ammonium chloride.
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Also known as:
E3 ubiquitin-protein ligase RNF38; MGC93195; Oip1; RING finger protein OIP1
RGD Orthologs
Alliance Genes
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
RNF38 (ring finger protein 38) HGNC
Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther
Mus musculus (house mouse):
Rnf38 (ring finger protein 38) HGNC
NCBI, OMA, HomoloGene, Inparanoid, Panther, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):
Rnf38 (ring finger protein 38) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
RNF38 (ring finger protein 38) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
RNF38 (ring finger protein 38) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Rnf38 (ring finger protein 38) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
RNF38 (ring finger protein 38) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):
RNF38 (ring finger protein 38) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Rnf38 (ring finger protein 38) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Alliance orthologs 3
Mus musculus (house mouse):
Rnf38 (ring finger protein 38)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB)
Homo sapiens (human):
RNF38 (ring finger protein 38)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB)
Danio rerio (zebrafish):
rnf38 (ring finger protein 38)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB)
Drosophila melanogaster (fruit fly):
mura
Alliance
DIOPT (OrthoFinder|OrthoInspector|PANTHER)
Latest Assembly:
Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Rnor_6.0 5 59,604,783 - 59,713,108 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 5 59,607,476 - 59,647,633 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 5 64,128,873 - 64,235,392 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 5 60,600,918 - 60,631,312 (-) NCBI RGSC3.4 rn4 RGSC3.4 RGSC_v3.1 5 60,601,097 - 60,631,491 (-) NCBI Celera 5 56,940,197 - 56,970,567 (-) NCBI Celera Cytogenetic Map 5 q22 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
2,3',4,4',5-Pentachlorobiphenyl increases expression ISO RGD:734249 6480464 2 more ... CTD PMID:31388691 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:734249 6480464 Tetrachlorodibenzodioxin affects the expression of RNF38 mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of RNF38 mRNA CTD PMID:32109520 2,4-dinitrotoluene affects expression EXP 6480464 2, 4-dinitrotoluene affects the expression of RNF38 mRNA CTD PMID:21346803 2-hydroxypropanoic acid increases expression ISO RGD:737292 6480464 Lactic Acid results in increased expression of RNF38 mRNA CTD PMID:30851411 3,4-methylenedioxymethamphetamine increases expression ISO RGD:734249 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in increased expression of RNF38 mRNA CTD PMID:20188158 3,4-methylenedioxymethamphetamine decreases expression ISO RGD:734249 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in decreased expression of RNF38 mRNA CTD PMID:26251327 aflatoxin B1 increases expression ISO RGD:734249 6480464 Aflatoxin B1 results in increased expression of RNF38 mRNA CTD PMID:19770486 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of RNF38 mRNA CTD PMID:16483693 antirheumatic drug decreases expression ISO RGD:737292 6480464 Antirheumatic Agents results in decreased expression of RNF38 mRNA CTD PMID:24449571 atrazine decreases expression ISO RGD:737292 6480464 Atrazine results in decreased expression of RNF38 mRNA CTD PMID:22378314 benzo[a]pyrene diol epoxide I decreases expression ISO RGD:737292 6480464 7 more ... CTD PMID:19150397 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of RNF38 mRNA CTD PMID:18180321 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of RNF38 mRNA CTD PMID:25181051 cadmium dichloride increases methylation EXP 6480464 Cadmium Chloride results in increased methylation of RNF38 promoter CTD PMID:22457795 carbon nanotube decreases expression ISO RGD:734249 6480464 Nanotubes, Carbon analog results in decreased expression of RNF38 mRNA CTD PMID:25554681 choline multiple interactions ISO RGD:734249 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of RNF38 gene CTD PMID:20938992 clofibrate increases expression ISO RGD:734249 6480464 Clofibrate results in increased expression of RNF38 mRNA CTD PMID:17585979 crocidolite asbestos decreases expression ISO RGD:734249 6480464 Asbestos, Crocidolite results in decreased expression of RNF38 mRNA CTD PMID:29279043 cyclosporin A increases expression ISO RGD:737292 6480464 Cyclosporine results in increased expression of RNF38 mRNA CTD PMID:25562108 cyclosporin A decreases expression ISO RGD:737292 6480464 Cyclosporine results in decreased expression of RNF38 mRNA CTD PMID:27989131 decabromodiphenyl ether increases expression EXP 6480464 decabromobiphenyl ether results in increased expression of RNF38 mRNA CTD PMID:23640034 doxorubicin decreases expression ISO RGD:737292 6480464 Doxorubicin results in decreased expression of RNF38 mRNA CTD PMID:29803840 endosulfan increases expression ISO RGD:737292 6480464 Endosulfan results in increased expression of RNF38 mRNA CTD PMID:26615145 ethanol affects splicing ISO RGD:734249 6480464 Ethanol affects the splicing of RNF38 mRNA CTD PMID:30319688 flavonoids increases expression EXP 6480464 Flavonoids results in increased expression of RNF38 mRNA CTD PMID:18035473 folic acid multiple interactions ISO RGD:734249 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of RNF38 gene CTD PMID:20938992 formaldehyde decreases expression ISO RGD:737292 6480464 Formaldehyde results in decreased expression of RNF38 mRNA CTD PMID:20655997 furan increases methylation EXP 6480464 furan results in increased methylation of RNF38 gene CTD PMID:22079235 gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of RNF38 mRNA CTD PMID:22061828 isotretinoin increases expression ISO RGD:737292 6480464 Isotretinoin results in increased expression of RNF38 mRNA CTD PMID:20436886 L-methionine multiple interactions ISO RGD:734249 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of RNF38 gene CTD PMID:20938992 lead diacetate decreases expression ISO RGD:734249 6480464 lead acetate results in decreased expression of RNF38 mRNA CTD PMID:20542052 lead(0) affects splicing ISO RGD:737292 6480464 Lead affects the splicing of RNF38 mRNA CTD PMID:28903495 lead(2+) affects splicing ISO RGD:737292 6480464 Lead affects the splicing of RNF38 mRNA CTD PMID:28903495 N-ethyl-N-nitrosourea increases mutagenesis ISO RGD:734249 6480464 Ethylnitrosourea results in increased mutagenesis of RNF38 intron CTD PMID:27776689 N-nitrosodiethylamine increases expression EXP 6480464 Diethylnitrosamine results in increased expression of RNF38 mRNA CTD PMID:20360939 paracetamol increases expression ISO RGD:737292 6480464 Acetaminophen results in increased expression of RNF38 mRNA CTD PMID:22230336 rac-lactic acid increases expression ISO RGD:737292 6480464 Lactic Acid results in increased expression of RNF38 mRNA CTD PMID:30851411 succimer multiple interactions ISO RGD:734249 6480464 [Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of RNF38 mRNA CTD PMID:26378955 sunitinib decreases expression ISO RGD:737292 6480464 Sunitinib results in decreased expression of RNF38 mRNA CTD PMID:31533062 urethane increases expression ISO RGD:737292 6480464 Urethane results in increased expression of RNF38 mRNA CTD PMID:28818685 valproic acid decreases expression ISO RGD:737292 6480464 Valproic Acid results in decreased expression of RNF38 mRNA CTD PMID:23179753 valproic acid affects expression ISO RGD:737292 6480464 Valproic Acid affects the expression of RNF38 mRNA CTD PMID:25979313
2,3',4,4',5-Pentachlorobiphenyl (ISO) 2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO) 2,4-dinitrotoluene (EXP) 2-hydroxypropanoic acid (ISO) 3,4-methylenedioxymethamphetamine (ISO) aflatoxin B1 (ISO) ammonium chloride (EXP) antirheumatic drug (ISO) atrazine (ISO) benzo[a]pyrene diol epoxide I (ISO) bisphenol A (EXP) cadmium dichloride (EXP) carbon nanotube (ISO) choline (ISO)
References
Additional References at PubMed
Genomics
QTLs in Region (Rnor_6.0)
2316959 Gluco59 Glucose level QTL 59 4.7 blood glucose amount (VT:0000188) blood glucose level (CMO:0000046) 5 35661945 117554267 Rat 1298067 Scl15 Serum cholesterol level QTL 15 4.8 0.001 blood cholesterol amount (VT:0000180) plasma total cholesterol level (CMO:0000585) 5 34402409 79402409 Rat 6903292 Stl28 Serum triglyceride level QTL 28 2.6 0.0073 blood triglyceride amount (VT:0002644) plasma triglyceride level (CMO:0000548) 5 29641661 74641661 Rat 6903306 Scl35 Serum cholesterol QTL 35 2.6 0.0073 blood cholesterol amount (VT:0000180) plasma total cholesterol level (CMO:0000585) 5 29641661 74641661 Rat 9589025 Epfw7 Epididymal fat weight QTL 7 20.66 0.001 epididymal fat pad mass (VT:0010421) epididymal fat pad weight to body weight ratio (CMO:0000658) 5 51804426 96804426 Rat 634305 Mamtr1 Mammary tumor resistance QTL 1 0.0001 mammary gland integrity trait (VT:0010552) mammary tumor number (CMO:0000343) 5 12651967 117554267 Rat 8552954 Pigfal14 Plasma insulin-like growth factor 1 level QTL 14 9 blood insulin-like growth factor amount (VT:0010479) plasma insulin-like growth factor 1 level (CMO:0001299) 5 21904363 66904363 Rat 7411561 Bw134 Body weight QTL 134 24 0.001 body mass (VT:0001259) body weight gain (CMO:0000420) 5 51804426 96804426 Rat 8662454 Vetf3 Vascular elastic tissue fragility QTL 3 27.4 artery integrity trait (VT:0010639) number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562) 5 1666587 71552720 Rat 7394712 Emca13 Estrogen-induced mammary cancer QTL 13 mammary gland integrity trait (VT:0010552) mammary tumor number (CMO:0000343) 5 9514842 103580403 Rat 1358353 Srcrtb2 Stress Responsive Cort Basal QTL 2 3.48 0.003 blood corticosterone amount (VT:0005345) plasma corticosterone level (CMO:0001173) 5 18847913 76608178 Rat 1331756 Rf34 Renal function QTL 34 4.16275 kidney blood vessel physiology trait (VT:0100012) absolute change in renal blood flow rate (CMO:0001168) 5 1 93273395 Rat 1331771 Rf35 Renal function QTL 35 4.36965 kidney blood vessel physiology trait (VT:0100012) absolute change in renal blood flow rate (CMO:0001168) 5 1 89432042 Rat 1331773 Scl26 Serum cholesterol level QTL 26 3.065 blood cholesterol amount (VT:0000180) serum total cholesterol level (CMO:0000363) 5 44404276 89432042 Rat 1331801 Rf33 Renal function QTL 33 4.149 kidney blood vessel physiology trait (VT:0100012) absolute change in renal vascular resistance (CMO:0001900) 5 44404276 134502294 Rat 1300115 Hrtrt7 Heart rate QTL 7 2.76 heart pumping trait (VT:2000009) heart rate (CMO:0000002) 5 48722038 93587756 Rat 1549845 Scl44 Serum cholesterol level QTL 44 6 blood cholesterol amount (VT:0000180) serum total cholesterol level (CMO:0000363) 5 40777918 154732375 Rat 1641912 Alcrsp18 Alcohol response QTL 18 response to alcohol trait (VT:0010489) duration of loss of righting reflex (CMO:0002289) 5 35788756 147487820 Rat 1641922 Alcrsp8 Alcohol response QTL 8 alcohol metabolism trait (VT:0015089) blood ethanol level (CMO:0000535) 5 35788756 70742105 Rat 1576312 Emca8 Estrogen-induced mammary cancer QTL 8 4.1 mammary gland integrity trait (VT:0010552) mammary tumor number (CMO:0000343) 5 51418671 147487820 Rat 1576314 Eutr1 Estrogen induced uterine response QTL 1 uterus integrity trait (VT:0010575) pyometritis severity score (CMO:0002009) 5 1525098 78720537 Rat 1576317 Eutr2 Estrogen induced uterine response QTL 2 0.01 uterus integrity trait (VT:0010575) pyometritis severity score (CMO:0002009) 5 35225432 108092802 Rat 1578766 Tcas11 Tongue tumor susceptibility QTL 11 4.12 tongue integrity trait (VT:0010553) number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950) 5 47745646 167946134 Rat 1578767 Stresp17 Stress response QTL 17 4.3 0.01 blood aldosterone amount (VT:0005346) plasma aldosterone level (CMO:0000551) 5 29078899 74078899 Rat 1578776 Stresp18 Stress response QTL 18 2.9 thymus mass (VT:0004954) thymus wet weight (CMO:0000855) 5 29078899 74078899 Rat 61359 Eaex Experimental allergic encephalomyelitis QTL x 3 nervous system integrity trait (VT:0010566) post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422) 5 56902367 101902367 Rat 1598807 Glom12 Glomerulus QTL 12 2.7 kidney glomerulus morphology trait (VT:0005325) index of glomerular damage (CMO:0001135) 5 34402409 79402409 Rat 70189 Mcs5 Mammary carcinoma susceptibility QTL 5 10.51 mammary gland integrity trait (VT:0010552) mammary tumor number (CMO:0000343) 5 56991667 137729065 Rat 70212 Niddm25 Non-insulin dependent diabetes mellitus QTL 25 3.54 blood glucose amount (VT:0000188) blood glucose level (CMO:0000046) 5 1 136640934 Rat 2290448 Scl54 Serum cholesterol level QTL 54 2.93 blood cholesterol amount (VT:0000180) plasma total cholesterol level (CMO:0000585) 5 31926122 136640934 Rat 2303574 Gluco42 Glucose level QTL 42 2 blood glucose amount (VT:0000188) blood glucose level (CMO:0000046) 5 55903593 100903593 Rat 2303615 Vencon7 Ventilatory control QTL 7 0.001 respiration trait (VT:0001943) respiration rate (CMO:0000289) 5 53309568 98309568 Rat 1600358 Mamtr5 Mammary tumor resistance QTL 5 mammary gland integrity trait (VT:0010552) mammary tumor number (CMO:0000343) 5 18847913 63847913 Rat 1302786 Kidm8 Kidney mass QTL 8 28.15 kidney mass (VT:0002707) both kidneys wet weight to body weight ratio (CMO:0000340) 5 34402409 79402409 Rat
