Spata31g1 (SPATA31 subfamily G member 1) - Rat Genome Database

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Gene: Spata31g1 (SPATA31 subfamily G member 1) Rattus norvegicus
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Symbol: Spata31g1
Name: SPATA31 subfamily G member 1
RGD ID: 2321337
Description: Orthologous to human SPATA31G1 (SPATA31 subfamily G member 1); INTERACTS WITH (-)-epigallocatechin 3-gallate (ortholog); aflatoxin B1 (ortholog); aristolochic acid A (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC100360821; rCG55159-like; spermatogenesis-associated protein 31G1; uncharacterized protein C9orf131 homolog
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8561,995,800 - 61,999,889 (+)NCBIGRCr8
mRatBN7.2557,199,980 - 57,204,069 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl557,200,000 - 57,204,070 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0558,416,058 - 58,421,991 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl558,416,432 - 58,420,342 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0562,941,527 - 62,945,979 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4559,461,938 - 59,465,896 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera555,789,097 - 55,795,032 (+)NCBICelera
Cytogenetic Map5q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


1 to 9 of 9 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Spata31g1Ratacromesomelic dysplasia, Maroteaux type  ISOSPATA31G1 (Homo sapiens)8554872ClinVar Annotator: match by term: Acromesomelic dysplasia 1 and Maroteaux typeClinVarPMID:28492532
Spata31g1Ratanauxetic dysplasia  ISOSPATA31G1 (Homo sapiens)8554872ClinVar Annotator: match by term: Anauxetic dysplasiaClinVarPMID:28492532
Spata31g1Ratautosomal recessive distal hereditary motor neuronopathy 2  ISOSPATA31G1 (Homo sapiens)8554872ClinVar Annotator: match by term: Autosomal recessive distal spinal muscular atrophy 2ClinVarPMID:28492532
Spata31g1Ratdistal arthrogryposis type 1A  ISOSPATA31G1 (Homo sapiens)8554872ClinVar Annotator: match by term: Arthrogryposis more ...ClinVarPMID:28492532
Spata31g1Ratfrontotemporal dementia and/or amyotrophic lateral sclerosis 6  ISOSPATA31G1 (Homo sapiens)8554872ClinVar Annotator: match by term: Frontotemporal dementia and/or amyotrophic lateral sclerosis 6ClinVarPMID:28492532
Spata31g1Ratgalactosemia  ISOSPATA31G1 (Homo sapiens)8554872ClinVar Annotator: match by term: Deficiency of UDPglucose-hexose-1-phosphate uridylyltransferaseClinVarPMID:28492532
Spata31g1Rathyperphosphatasia with impaired intellectual development syndrome 2  ISOSPATA31G1 (Homo sapiens)8554872ClinVar Annotator: match by term: GLYCOSYLPHOSPHATIDYLINOSITOL BIOSYNTHESIS DEFECT 6ClinVarPMID:22683086 more ...
Spata31g1Ratparaplegia  ISOSPATA31G1 (Homo sapiens)8554872ClinVar Annotator: match by term: Spastic paraplegiaClinVarPMID:23332916 more ...
Spata31g1Ratprimary ciliary dyskinesia  ISOSPATA31G1 (Homo sapiens)8554872ClinVar Annotator: match by term: Primary ciliary dyskinesiaClinVarPMID:28492532
1 to 9 of 9 rows


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Spata31g1Rat(-)-epigallocatechin 3-gallate multiple interactionsISOSPATA31G1 (Homo sapiens)6480464[potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of SPATA31G1 mRNACTDPMID:22079256
Spata31g1Rataflatoxin B1 increases methylationISOSPATA31G1 (Homo sapiens)6480464Aflatoxin B1 results in increased methylation of SPATA31G1 geneCTDPMID:27153756
Spata31g1Rataristolochic acid A increases expressionISOSPATA31G1 (Homo sapiens)6480464aristolochic acid I results in increased expression of SPATA31G1 mRNACTDPMID:33212167
Spata31g1Ratbenzo[a]pyrene increases mutagenesisISOSPATA31G1 (Homo sapiens)6480464Benzo(a)pyrene results in increased mutagenesis of SPATA31G1 geneCTDPMID:25435355
Spata31g1Ratbenzo[a]pyrene affects methylationISOSPATA31G1 (Homo sapiens)6480464Benzo(a)pyrene affects the methylation of SPATA31G1 exonCTDPMID:27901495
Spata31g1Ratfolic acid decreases expressionISOSPATA31G1 (Homo sapiens)6480464Folic Acid results in decreased expression of SPATA31G1 mRNACTDPMID:21867686
Spata31g1Ratpotassium chromate multiple interactionsISOSPATA31G1 (Homo sapiens)6480464[potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of SPATA31G1 mRNACTDPMID:22079256
Spata31g1Ratpotassium chromate increases expressionISOSPATA31G1 (Homo sapiens)6480464potassium chromate(VI) results in increased expression of SPATA31G1 mRNACTDPMID:22079256


#
Reference Title
Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions


Spata31g1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8561,995,800 - 61,999,889 (+)NCBIGRCr8
mRatBN7.2557,199,980 - 57,204,069 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl557,200,000 - 57,204,070 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0558,416,058 - 58,421,991 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl558,416,432 - 58,420,342 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0562,941,527 - 62,945,979 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4559,461,938 - 59,465,896 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera555,789,097 - 55,795,032 (+)NCBICelera
Cytogenetic Map5q22NCBI
SPATA31G1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38935,041,095 - 35,045,986 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl935,041,095 - 35,045,986 (+)EnsemblGRCh38hg38GRCh38
GRCh37935,041,092 - 35,045,983 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36935,031,102 - 35,035,988 (+)NCBINCBI36Build 36hg18NCBI36
Celera934,973,075 - 34,977,961 (+)NCBICelera
Cytogenetic Map9p13.3NCBI
HuRef934,996,685 - 35,001,571 (+)NCBIHuRef
CHM1_1935,040,938 - 35,045,824 (+)NCBICHM1_1
T2T-CHM13v2.0935,060,274 - 35,065,165 (+)NCBIT2T-CHM13v2.0
Spata31g1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39442,969,946 - 42,974,325 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl442,969,604 - 42,983,640 (+)EnsemblGRCm39 Ensembl
GRCm38442,969,946 - 42,974,325 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl442,969,604 - 42,983,640 (+)EnsemblGRCm38mm10GRCm38
MGSCv37442,982,832 - 42,987,197 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36442,991,060 - 42,995,425 (+)NCBIMGSCv36mm8
Celera443,000,115 - 43,004,480 (+)NCBICelera
Cytogenetic Map4A5NCBI
cM Map422.95NCBI
Spata31g1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495807216 - 1,146 (+)NCBIChiLan1.0ChiLan1.0
SPATA31G1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21189,532,976 - 89,571,418 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1989,539,343 - 89,572,394 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0934,892,418 - 34,896,577 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1935,698,610 - 35,702,395 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl935,697,549 - 35,702,395 (+)Ensemblpanpan1.1panPan2
SPATA31G1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11151,624,571 - 51,629,189 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1151,625,604 - 51,629,131 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1150,193,829 - 50,197,939 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01152,690,464 - 52,694,574 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1152,691,048 - 52,694,575 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11151,234,568 - 51,238,678 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01151,219,706 - 51,223,816 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01151,921,525 - 51,925,635 (+)NCBIUU_Cfam_GSD_1.0
Spata31g1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947166,527,515 - 166,531,756 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365243,075,250 - 3,079,233 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365243,074,901 - 3,079,980 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SPATA31G1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1235,842,554 - 235,848,767 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11235,844,826 - 235,849,556 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21263,369,897 - 263,374,462 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SPATA31G1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11245,571,060 - 45,575,282 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1245,571,177 - 45,574,796 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603842,687,678 - 42,691,430 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Spata31g1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624915240,678 - 246,151 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Spata31g1
25 total Variants

Predicted Target Of
Summary Value
Count of predictions:58
Count of miRNA genes:27
Interacting mature miRNAs:29
Transcripts:ENSRNOT00000039366, ENSRNOT00000073151
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 35 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1578776Stresp18Stress response QTL 182.9thymus mass (VT:0004954)thymus wet weight (CMO:0000855)52795544072955440Rat
1298067Scl15Serum cholesterol level QTL 154.80.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53321566578215665Rat
1300115Hrtrt7Heart rate QTL 72.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)54786906290099692Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51131345958Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)51887394774251464Rat
634305Mamtr1Mammary tumor resistance QTL 10.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)512789751113558310Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)543726656129132602Rat
1598807Glom12Glomerulus QTL 122.7kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)53321566578215665Rat
1302786Kidm8Kidney mass QTL 828.15kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)53321566578215665Rat

1 to 10 of 35 rows



alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
6 11 15 40 36 38 12 24 12 6 95 60 22 9 29 26



Ensembl Acc Id: ENSRNOT00000039366   ⟹   ENSRNOP00000035213
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl557,200,000 - 57,204,070 (+)Ensembl
Rnor_6.0 Ensembl558,416,432 - 58,420,342 (+)Ensembl
RefSeq Acc Id: NM_001419539   ⟹   NP_001406468
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8561,995,800 - 61,999,889 (+)NCBI
mRatBN7.2557,199,980 - 57,204,069 (+)NCBI
Protein RefSeqs NP_001406468 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL98715 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000035213
  ENSRNOP00000035213.7
Ensembl Acc Id: ENSRNOP00000035213   ⟸   ENSRNOT00000039366
RefSeq Acc Id: NP_001406468   ⟸   NM_001419539
- UniProtKB: D4A3J0 (UniProtKB/TrEMBL),   A6IIZ5 (UniProtKB/TrEMBL)

Name Modeler Protein Id AA Range Protein Structure
AF-D4A3J0-F1-model_v2 AlphaFold D4A3J0 1-1191 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13693671
Promoter ID:EPDNEW_R4191
Type:initiation region
Name:LOC100360821_1
Description:rCG55159-like
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0558,416,406 - 58,416,466EPDNEW


1 to 12 of 12 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-41528 BioCyc
Ensembl Genes ENSRNOG00000022601 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000039366 ENTREZGENE
  ENSRNOT00000039366.7 UniProtKB/TrEMBL
InterPro UPF_C9orf131 UniProtKB/TrEMBL
NCBI Gene 100360821 ENTREZGENE
PANTHER PTHR21777 UniProtKB/TrEMBL
  RCG55159-LIKE UniProtKB/TrEMBL
PhenoGen Spata31g1 PhenoGen
RatGTEx ENSRNOG00000022601 RatGTEx
UniProt A6IIZ5 ENTREZGENE, UniProtKB/TrEMBL
  D4A3J0 ENTREZGENE, UniProtKB/TrEMBL
1 to 12 of 12 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-14 Spata31g1  SPATA31 subfamily G member 1  LOC100360821  rCG55159-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-05-05 LOC100360821  rCG55159-like      Symbol and Name status set to provisional 70820 PROVISIONAL