Zfp37 (zinc finger protein 37) - Rat Genome Database

Name: Zfp37
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Zfp37 (zinc finger protein 37) Rattus norvegicus

Analyze

Symbol:

Zfp37

Name:

zinc finger protein 37

RGD ID:

620723

Description:

Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in cell differentiation. Predicted to be located in nucleus. Orthologous to human ZFP37 (ZFP37 zinc finger protein); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC102555249; zfp-37; zinc finger protein 37-like

RGD Orthologs

Human

Mouse

Dog

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ZFP37 (ZFP37 zinc finger protein)	RGD	RGD
Mus musculus (house mouse):	Zfp37 (zinc finger protein 37)	RGD	RGD
Canis lupus familiaris (dog):	ZFP37 (ZFP37 zinc finger protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	ZFP37 (ZFP37 zinc finger protein)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Zfp37 (zinc finger protein 37)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG2712	Alliance	DIOPT (Ensembl Compara\|PANTHER)

Related Pseudogenes:

Zfp37-ps1

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	5	75,598,732 - 75,638,896 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	75,598,732 - 75,638,942 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	77,998,009 - 78,038,479 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	79,819,683 - 79,855,549 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	79,791,846 - 79,831,093 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	77,829,492 - 77,945,361 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	77,941,148 - 77,945,016 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	81,827,732 - 81,869,391 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	79,119,307 - 79,152,270 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	78,703,619 - 79,157,374 (-)	NCBI
Celera	5	74,542,395 - 74,579,036 (-)	NCBI		Celera
Cytogenetic Map	5	q24	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Experimental Liver Cirrhosis (ISO)

genetic disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

1-naphthyl isothiocyanate (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3,4-methylenedioxymethamphetamine (EXP)

3-methylcholanthrene (ISO)

3H-1,2-dithiole-3-thione (EXP)

4,4'-diaminodiphenylmethane (EXP)

6-propyl-2-thiouracil (EXP)

acetaldehyde (ISO)

aflatoxin B1 (EXP,ISO)

amitrole (EXP)

ammonium chloride (EXP)

atrazine (EXP)

benzo[a]pyrene (ISO)

bis(2-chloroethyl) sulfide (ISO)

bisphenol A (EXP,ISO)

cadmium dichloride (ISO)

chlorpyrifos (ISO)

cisplatin (ISO)

copper(II) sulfate (ISO)

dichloromethane (ISO)

diethyl maleate (EXP)

dioxygen (ISO)

dorsomorphin (ISO)

emodin (ISO)

flutamide (EXP)

folic acid (ISO)

fulvestrant (ISO)

furan (EXP)

methimazole (EXP)

Muraglitazar (EXP)

N-nitrosodiethylamine (EXP)

N-nitrosodimethylamine (EXP)

paracetamol (EXP,ISO)

perfluorooctanoic acid (EXP)

phenethyl caffeate (EXP)

phenylmercury acetate (ISO)

pirinixic acid (EXP)

potassium dichromate (ISO)

propiconazole (EXP)

quercetin (ISO)

rotenone (EXP)

SB 431542 (ISO)

sodium dichromate (EXP)

sodium fluoride (ISO)

sulfadimethoxine (EXP)

sunitinib (ISO)

Tesaglitazar (EXP)

testosterone enanthate (ISO)

tetrachloromethane (EXP)

thioacetamide (EXP)

trichloroethene (EXP)

trichostatin A (ISO)

troglitazone (EXP)

urethane (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell differentiation (IEP)

negative regulation of transcription by RNA polymerase II (IBA)

regulation of DNA-templated transcription (IEA)

Cellular Component

nucleus (IEA)

Molecular Function

DNA-binding transcription repressor activity, RNA polymerase II-specific (IBA)

metal ion binding (IEA)

RNA polymerase II transcription regulatory region sequence-specific DNA binding (IBA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
5.	GOA pipeline	RGD automated data pipeline
6.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
8.	Identification of a novel peroxisome proliferator responsive cDNA isolated from rat hepatocytes as the zinc-finger protein ZFP-37.	Vanden Heuvel JP, etal., Toxicol Appl Pharmacol 1998 Sep;152(1):107-18.

Additional References at PubMed

PMID:12477932

Genomics

Comparative Map Data

Zfp37
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	5	75,598,732 - 75,638,896 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	75,598,732 - 75,638,942 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	77,998,009 - 78,038,479 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	79,819,683 - 79,855,549 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	79,791,846 - 79,831,093 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	77,829,492 - 77,945,361 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	77,941,148 - 77,945,016 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	81,827,732 - 81,869,391 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	79,119,307 - 79,152,270 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	78,703,619 - 79,157,374 (-)	NCBI
Celera	5	74,542,395 - 74,579,036 (-)	NCBI		Celera
Cytogenetic Map	5	q24	NCBI

ZFP37
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	9	113,038,377 - 113,056,724 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	9	113,038,377 - 113,056,759 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	9	115,800,657 - 115,819,004 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	114,843,995 - 114,858,817 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	9	112,883,728 - 112,898,551	NCBI
Celera	9	86,148,311 - 86,163,133 (+)	NCBI		Celera
Cytogenetic Map	9	q32	NCBI
HuRef	9	85,402,280 - 85,417,102 (-)	NCBI		HuRef
CHM1_1	9	115,951,535 - 115,966,362 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	9	125,191,240 - 125,228,482 (-)	NCBI		T2T-CHM13v2.0

Zfp37
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	62,107,774 - 62,127,634 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	62,107,777 - 62,149,284 (-)	Ensembl		GRCm39 Ensembl
GRCm38	4	62,189,537 - 62,209,129 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	62,189,540 - 62,231,047 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	61,850,577 - 61,869,580 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	61,675,904 - 61,694,788 (-)	NCBI		MGSCv36	mm8
Celera	4	60,862,602 - 60,881,623 (-)	NCBI		Celera
Cytogenetic Map	4	B3	NCBI
cM Map	4	33.04	NCBI

ZFP37
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	11	67,424,840 - 67,456,771 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	11	67,442,836 - 67,460,280 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	11	65,847,821 - 65,861,366 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	11	68,567,301 - 68,583,812 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	11	68,567,359 - 68,583,792 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	11	67,084,629 - 67,102,746 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	11	67,106,682 - 67,121,382 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	11	67,851,417 - 67,867,021 (-)	NCBI		UU_Cfam_GSD_1.0

Variants

Variants in Zfp37
325 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	15
Count of miRNA genes:	15
Interacting mature miRNAs:	15
Transcripts:	ENSRNOT00000018209
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1331756	Rf34	Renal function QTL 34	4.16275		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	5	1	90450412	Rat
70212	Niddm25	Non-insulin dependent diabetes mellitus QTL 25	3.54		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	5	1	131345958	Rat
1331771	Rf35	Renal function QTL 35	4.36965		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	5	729470	86724018	Rat
1576314	Eutr1	Estrogen induced uterine response QTL 1			uterus integrity trait (VT:0010575)	pyometritis severity score (CMO:0002009)	5	2138965	166875058	Rat
7394712	Emca13	Estrogen-induced mammary cancer QTL 13			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	9823266	99753708	Rat
634305	Mamtr1	Mammary tumor resistance QTL 1		0.0001	mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	12789751	113558310	Rat
2290448	Scl54	Serum cholesterol level QTL 54	2.93		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	31663789	131345958	Rat
1598807	Glom12	Glomerulus QTL 12	2.7		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	5	33215665	78215665	Rat
1298067	Scl15	Serum cholesterol level QTL 15	4.8	0.001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	33215665	78215665	Rat
1302786	Kidm8	Kidney mass QTL 8	28.15		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	5	33215665	78215665	Rat
1576317	Eutr2	Estrogen induced uterine response QTL 2		0.01	uterus integrity trait (VT:0010575)	pyometritis severity score (CMO:0002009)	5	34730116	104251008	Rat
2316959	Gluco59	Glucose level QTL 59	4.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	5	34944474	113558310	Rat
1641912	Alcrsp18	Alcohol response QTL 18			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	5	35189153	141643988	Rat
1549845	Scl44	Serum cholesterol level QTL 44	6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	40128307	148607290	Rat
1331773	Scl26	Serum cholesterol level QTL 26	3.065		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	43726656	86724018	Rat
1331801	Rf33	Renal function QTL 33	4.149		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	5	43726656	129132602	Rat
1578766	Tcas11	Tongue tumor susceptibility QTL 11	4.12		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	5	46711509	161317411	Rat
1300115	Hrtrt7	Heart rate QTL 7	2.76		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	5	47869062	90099692	Rat
9589025	Epfw7	Epididymal fat weight QTL 7	20.66	0.001	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	5	49463600	94463600	Rat
7411561	Bw134	Body weight QTL 134	24	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	49463600	94463600	Rat
1576312	Emca8	Estrogen-induced mammary cancer QTL 8	4.1		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	50328551	141643988	Rat
2303615	Vencon7	Ventilatory control QTL 7		0.001	respiration trait (VT:0001943)	respiration rate (CMO:0000289)	5	50983895	95983895	Rat
2303574	Gluco42	Glucose level QTL 42	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	5	53496719	98496719	Rat
61359	Eaex	Experimental allergic encephalomyelitis QTL x	3		nervous system integrity trait (VT:0010566)	post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)	5	55715622	100715622	Rat
70189	Mcs5	Mammary carcinoma susceptibility QTL 5	10.51		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	55805606	132207589	Rat
1358895	Bp254	Blood pressure QTL 254	3.6	0.0003	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	5	58829236	128034027	Rat
61426	Scl2	Serum cholesterol level QTL 2	7.3	0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	59793399	143070159	Rat
2316954	Rf57	Renal function QTL 57	0		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	5	59793528	90450144	Rat
2316957	Pur21	Proteinuria QTL 21	6.2		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	5	59793528	113558156	Rat
61386	Bp49	Blood pressure QTL 49	16.6		cerebrum integrity trait (VT:0010549)	brain infarction volume (CMO:0001013)	5	60293434	98603051	Rat
61393	Bp7	Blood pressure QTL 7	4.5	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	60293434	161481680	Rat
2290005	Mcs24	Mammary carcinoma susceptibility QTL 24			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	64719390	109719390	Rat
2306971	Anxrr21	Anxiety related response QTL 21	9.47		fear/anxiety-related behavior trait (VT:1000241)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	5	66174080	124160948	Rat
2312671	Scl64	Serum cholesterol level QTL 64		0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	68984307	104251008	Rat
61380	Edpm5	Estrogen-dependent pituitary mass QTL 5	4.5	0.92	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	5	68984307	104251008	Rat
1357396	Bw44	Body weight QTL 44	4.19		body mass (VT:0001259)	body weight (CMO:0000012)	5	68984307	104251008	Rat
1357402	Bw46	Body weight QTL 46	4.47		body mass (VT:0001259)	body mass index (BMI) (CMO:0000105)	5	68984307	104251008	Rat
2302381	Bw84	Body weight QTL 84	4.47		body mass (VT:0001259)	body mass index (BMI) (CMO:0000105)	5	68984307	104251008	Rat
1354598	Srn6	Serum renin concentration QTL 6	3.8		blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	5	69540295	151018848	Rat

Markers in Region

BE107053

Rat Assembly	Chr	Position (strand)	Source	JBrowse
RH 3.4 Map	5	553.9	UniSTS
Cytogenetic Map	5	q24	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium		2							38	12	20	2
Low	2	41	48	32	19	32	8	11	36	23	21	9	8
Below cutoff	1		9	9		9

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_058209	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008763803	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039109135	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039109136	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039109137	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039109138	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039109139	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039109140	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039109141	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AF072439	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC166844	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CB727538	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473978	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000161	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000056900 ⟹ ENSRNOP00000053737

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	75,600,068 - 75,638,942 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000076223 ⟹ ENSRNOP00000067999

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	5	77,941,148 - 77,945,016 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000100418 ⟹ ENSRNOP00000097307

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	75,598,732 - 75,636,607 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000100489 ⟹ ENSRNOP00000089492

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	75,598,732 - 75,638,942 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000101002 ⟹ ENSRNOP00000077492

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	75,598,732 - 75,636,099 (-)	Ensembl

RefSeq Acc Id:

NM_058209 ⟹ NP_478116

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	5	75,598,732 - 75,638,607 (-)	NCBI
Rnor_5.0	5	81,827,732 - 81,869,391 (-)	NCBI
RGSC_v3.4	5	79,119,307 - 79,152,270 (-)	RGD
Celera	5	74,542,395 - 74,579,036 (-)	RGD

Sequence:

show sequence

ATGTCGGCCTCTGACTCCAACAAGGACCTGACAAAGCCAGAGGCGGTGGGCCGGAGGAGTACGG
ACAAAGCCAGGCGTCCGAAGGAGATGGCTACACCCGAGCCTGCAGAGAGCGATGCGAAGGAATG
GGAGCAGCTGGAACCTGGGCAGAGAAACGTGTACAAGGATACAAAGCTAGAGACCTGCAGCAAT
CCAGCCTCGATGGGAAATCAAGATCCCAAACAAGGCCTAGTCTCTAAGTTGGATGGAGAAGAAG
AGCGGTGGTCTTCAGTGAGGGCAAATAAGAACAGCTCAAGTAGTCTGCACAGACTCAAGAAAAC
AGGAACCAGTGCAAAGGTCCAACAAGATGGTGCACAGACGGAGGGGAAGCAGAAATTCCAAAGG
AAACTCACTTCAGAAGTGACATTCAGGAAGAAAAGTTCAAACAGTAAGAAAAGCAGTGAGTGTA
CATTGTTGGAGAAGAAAAATGTCCATTCAAAACATGATCCTTCTGAAAAAAGATTGCATAAATC
CAATTTGTATGGGAAGAACTTGAATCAGAATTTAGACTTACCCAGTCAGATTAAAATCTCTGCG
AAAAAGAAACCCGATACAGCTAATGAATATAGGAAATCACTCAGCCATTCTGCATCCGATGTGA
ACAGAGATGAAATTTCAACTAGAAAGAAATGTGACAAGTCACCCAACAATAAATTGTTTGGTAA
AGGTGACAAAAACCAAACAGGCAAGAAATGTGAGAAAGTATGCCGTCATAGCGCATCCCATACC
AAGGAAGACAAAATTCATACCGGGGAGAAACGGAAATCACCCTGCCGTAGTCCATCTAAATCTG
ACAAGGCTCCAGGCTCTGGGAAACCTTATGAATGTAATCAATGTGGGAAGGTCCTCAGCCATAA
ACAGGGGCTCCTTGACCATCAAAGAACTCATACCGGGGAGAAACCATATGAATGTAACGAATGC
GGGATAGCTTTCAGCCAAAAGTCCCACCTTGTCGTACATCAGAGAACTCACACTGGGGAAAAGC
CATACGAGTGTGTCCAGTGTGGCAAAGCCCACGGTCACAAACATGCCCTCACTGACCACCTGAG
AATCCATACCGGAGAAAAGCCCTACAAATGTAATGAATGTGGCAAAACCTTTAGGCACAGCTCA
AACCTTATGCAACACATAAGATCTCACACGGGCGAGAAGCCGTACGAGTGTAAGGAGTGTGGCA
AATCCTTCAGATATAATTCATCTCTCACCGAACATGTGAGAACACACACAGGCGAAATACCCTA
TGAATGTAATGAATGTGGCAAAGCTTTTAAGTATGGCTCATCCCTGACTAAACACATGCGAATT
CATACAGGCGAGAAGCCATTTGAATGTACTGAGTGTGGGAAGACTTTTAGCAAAAAGTCACACC
TAGTTATACATCAGAGAACTCACACGAAGGAGAAACCTTATAAATGTAAGGAGTGTGGCAAAGC
CTTTGGACATAGCTCATCTCTTACCTACCATCTGAGAACTCACACCGGGGATTGCCCCTTTGAA
TGTAATCAATGTGGCAAGGCCTTCAAGCAAATTGAGGGCCTTACTCAACACCAGAGAGTTCATA
CAGGAGAGAAACCCTATGAGTGTGTCGAATGTGGAAAAGCCTTCAGTCAGAAGTCACACCTCAT
TGTACATCAGAGAACTCATACAGGGGAGAAGCCCTTTGAATGTTATGAGTGTGGAAAAGCCTTC
AATGCAAAATCACAACTTGTTATTCATCAGAGATCCCACACTGGAGAGAAACCCTATGAGTGTG
TTGAATGTGGTAAAGCCTTCAAACAAAATGCTTCTCTTACCAGACATATGAAGATTCACTCGGA
AGAACAATCTCAGGAGGAAGATTAATGTGGGAACTCTGACAGGTGACTGGTTTGGTATTGTTTA
ACCTTCAAGATGGTCTCAGTTTGATGATGTTAGAGTCTTTTTTTAAGAGTATGAATCTTTACAT
GAGATCATTAGATGGTAATAAAGTTTAAACTTCATCCTAAACCTTTCCAGGAAATAGTGTGTTT
TTACACTTGTTACAAATTGTCTCCATATTTAGATTAAAATAGGAAACTCTTAAAATTGTGAACA
AGGAGATGAGAAGATAGCATAATCAGTAAAAGCTTGTTAAGTGGTATAGAGATCTGAATCCCAT
CCCTAGGACGTCAAAATTTAAATGTGCTGCTGTGCTCTTGCAACCTCATAACTGGGAAAGTTGA
GGCAAGAGAATCCCTGAGACTACCTGGCCAATCAGAATTGCTTAATTTACAAGCCATAGGTCAG
AGGGAAAACCTTTTAAAGACAGGGTACAGTGCTCCTGAGAAACGGTACTCGTGTTGACACACAC
ACACACACACACACACACACACACACACACTAATTTGTGAAAATGTTTATTAGGGCAACAAATG
ATAAAATAAAATAATTCATGAACTTTTTAGGCGTTTGCTTAGCCACCACAATTATTTAATTTGC
ATTTATGCTTACTGCATACTAGGGCCTGTGTAAAATACAGATGAGGGTACCCTCTGGTAACGTA
AGCTTTCTTTGTTAATGTCTTCGTTAGCTTCTGAATTAATAGAAAACTTTGGGGAGTTCTTTTG
TTTTGTTTTGTTTGAGACAGAATCTTACCAGCCTGGAACTTGTTATGTAGACCAGGCTGACCTT
GAACTTGTTATGTAGACCGGGCTGGCCTTGAACTCACAGAGATGTGCCTGTTTCTGCCTCCCAA
GTGCTAGAATTAAAGACTTCAATAGAAAACTTTGAGGGGTTTTGTCTAAATATTGTTAATAAGA
GTTGACTAAAAATGTGGAAAACAGCTGGCAATGTGTTGTAGTGAATGCTACGTCCTATATCGTT
TAAGTACAGAAATCAGATTGTTGAACAGTGTATATAGTATGTTCTCACTGTGGACAAAGACTGT
GTATGTGTGTCTGTCTTTTTATGCCTCTGTGTACATGTATATGCATTTATACCGATATATTTGT
ATATGAATAGACTTGTTTTTTTAAACATAGAAGAAAATAGGGGCTACCACTGAACACAGGAGTG
CAGCATGGATGTCTGACATTTTTATCATGTACATGAGACTTATTCAAATATATATCACATTAAA
ATACTTTTATATGTACAAATTAACACAGTTTAAAAATACAGCCGAGTCTATTCCACAGTGTTAT
TTGACAAAGTGACCTGAGATTTCTATACTCATTTATGAACAACAAGTTTGAAGTATGGCATTAA
ACCTCGATATTCATGAAGTTTCCTATAGAACACAGATTTTGTTAACATGACTCATAACTGTAAC
TACTTTATTTCTCTTGTTTGCTATTAAAAACTCAGGATGGA

hide sequence

RefSeq Acc Id:

XM_039109135 ⟹ XP_038965063

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	5	75,598,732 - 75,638,890 (-)	NCBI

RefSeq Acc Id:

XM_039109136 ⟹ XP_038965064

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	5	75,598,732 - 75,638,896 (-)	NCBI

RefSeq Acc Id:

XM_039109137 ⟹ XP_038965065

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	5	75,598,732 - 75,638,896 (-)	NCBI

RefSeq Acc Id:

XM_039109138 ⟹ XP_038965066

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	5	75,598,732 - 75,638,077 (-)	NCBI

RefSeq Acc Id:

XM_039109139 ⟹ XP_038965067

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	5	75,598,732 - 75,638,033 (-)	NCBI

RefSeq Acc Id:

XM_039109140 ⟹ XP_038965068

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	5	75,598,732 - 75,638,097 (-)	NCBI

RefSeq Acc Id:

XM_039109141 ⟹ XP_038965069

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	5	75,598,732 - 75,638,370 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_478116	(Get FASTA)	NCBI Sequence Viewer
	XP_038965063	(Get FASTA)	NCBI Sequence Viewer
	XP_038965064	(Get FASTA)	NCBI Sequence Viewer
	XP_038965065	(Get FASTA)	NCBI Sequence Viewer
	XP_038965066	(Get FASTA)	NCBI Sequence Viewer
	XP_038965067	(Get FASTA)	NCBI Sequence Viewer
	XP_038965068	(Get FASTA)	NCBI Sequence Viewer
	XP_038965069	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAC24590	(Get FASTA)	NCBI Sequence Viewer
	EDM10572	(Get FASTA)	NCBI Sequence Viewer
	O88553	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_478116 ⟸ NM_058209

- UniProtKB:

A0A8I6AAE9 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSASDSNKDLTKPEAVGRRSTDKARRPKEMATPEPAESDAKEWEQLEPGQRNVYKDTKLETCSN
PASMGNQDPKQGLVSKLDGEEERWSSVRANKNSSSSLHRLKKTGTSAKVQQDGAQTEGKQKFQR
KLTSEVTFRKKSSNSKKSSECTLLEKKNVHSKHDPSEKRLHKSNLYGKNLNQNLDLPSQIKISA
KKKPDTANEYRKSLSHSASDVNRDEISTRKKCDKSPNNKLFGKGDKNQTGKKCEKVCRHSASHT
KEDKIHTGEKRKSPCRSPSKSDKAPGSGKPYECNQCGKVLSHKQGLLDHQRTHTGEKPYECNEC
GIAFSQKSHLVVHQRTHTGEKPYECVQCGKAHGHKHALTDHLRIHTGEKPYKCNECGKTFRHSS
NLMQHIRSHTGEKPYECKECGKSFRYNSSLTEHVRTHTGEIPYECNECGKAFKYGSSLTKHMRI
HTGEKPFECTECGKTFSKKSHLVIHQRTHTKEKPYKCKECGKAFGHSSSLTYHLRTHTGDCPFE
CNQCGKAFKQIEGLTQHQRVHTGEKPYECVECGKAFSQKSHLIVHQRTHTGEKPFECYECGKAF
NAKSQLVIHQRSHTGEKPYECVECGKAFKQNASLTRHMKIHSEEQSQEED

hide sequence

RefSeq Acc Id:

ENSRNOP00000067999 ⟸ ENSRNOT00000076223

RefSeq Acc Id:	XP_038965065 ⟸ XM_039109137
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038965064 ⟸ XM_039109136
- Peptide Label:	isoform X2
- UniProtKB:	F1LYQ2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038965063 ⟸ XM_039109135
- Peptide Label:	isoform X1
- UniProtKB:	A6J7T5 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038965069 ⟸ XM_039109141
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_038965068 ⟸ XM_039109140
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_038965066 ⟸ XM_039109138
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_038965067 ⟸ XM_039109139
- Peptide Label:	isoform X4

RefSeq Acc Id:

ENSRNOP00000097307 ⟸ ENSRNOT00000100418

RefSeq Acc Id:

ENSRNOP00000089492 ⟸ ENSRNOT00000100489

RefSeq Acc Id:

ENSRNOP00000077492 ⟸ ENSRNOT00000101002

RefSeq Acc Id:

ENSRNOP00000053737 ⟸ ENSRNOT00000056900

Protein Domains

C2H2-type KRAB

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-O88553-F1-model_v2	AlphaFold	O88553	1-601	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:620723	AgrOrtholog
BioCyc Gene	G2FUF-41106	BioCyc
Ensembl Genes	ENSRNOG00000051078	Ensembl
	ENSRNOG00000069865	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000053737	ENTREZGENE
	ENSRNOP00000053737.5	UniProtKB/TrEMBL
	ENSRNOP00000077492	ENTREZGENE
	ENSRNOP00000077492.1	UniProtKB/TrEMBL
	ENSRNOP00000089492	ENTREZGENE
	ENSRNOP00000089492.1	UniProtKB/TrEMBL
	ENSRNOP00000097307.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000056900	ENTREZGENE
	ENSRNOT00000056900.6	UniProtKB/TrEMBL
	ENSRNOT00000100418.1	UniProtKB/TrEMBL
	ENSRNOT00000100489	ENTREZGENE
	ENSRNOT00000100489.1	UniProtKB/TrEMBL
	ENSRNOT00000101002	ENTREZGENE
	ENSRNOT00000101002.1	UniProtKB/TrEMBL
Gene3D-CATH	6.10.140.140	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Classic Zinc Finger	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	KRAB	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	KRAB_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Znf_C2H2_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Znf_C2H2_type	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:115768	UniProtKB/TrEMBL
NCBI Gene	115768	ENTREZGENE
PANTHER	ENDOTHELIAL ZINC FINGER PROTEIN INDUCED BY TUMOR NECROSIS FACTOR ALPHA	UniProtKB/TrEMBL
	KRAB AND ZINC FINGER DOMAIN-CONTAINING	UniProtKB/TrEMBL
	SIMILAR TO ZINC FINGER PROTEIN 84 (HPF2)	UniProtKB/TrEMBL
	ZINC FINGER AND SCAN DOMAIN-CONTAINING	UniProtKB/TrEMBL
	ZINC FINGER PROTEIN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ZINC FINGER PROTEIN 26	UniProtKB/TrEMBL
	ZINC FINGER PROTEIN 345-RELATED	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	KRAB	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	zf-C2H2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Zfp37	PhenoGen
PROSITE	KRAB	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ZINC_FINGER_C2H2_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ZINC_FINGER_C2H2_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	KRAB	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ZnF_C2H2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF109640	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SSF57667	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8I5YBV1_RAT	UniProtKB/TrEMBL
	A0A8I6AAE9	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6AUS7_RAT	UniProtKB/TrEMBL
	A6J7T5	ENTREZGENE, UniProtKB/TrEMBL
	F1LYQ2	ENTREZGENE, UniProtKB/TrEMBL
	O88553	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-07-29	Zfp37	zinc finger protein 37	LOC102555249	zinc finger protein 37-like	Data Merged	737654	PROVISIONAL
2013-12-17	LOC102555249	zinc finger protein 37-like			Symbol and Name status set to provisional	70820	PROVISIONAL
2004-02-26	Zfp37	zinc finger protein 37			Symbol and Name status set to approved	625702	APPROVED
2002-08-07	Zfp37				Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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