B4galt1 (beta-1,4-galactosyltransferase 1)

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Gene: B4galt1 (beta-1,4-galactosyltransferase 1) Rattus norvegicus

Analyze

Symbol:

B4galt1

Name:

beta-1,4-galactosyltransferase 1

RGD ID:

620900

Description:

Predicted to have several functions, including UDP-galactosyltransferase activity; laminin binding activity involved in cell-matrix adhesion; and tubulin binding activity. Involved in response to wounding. Predicted to localize to several cellular components, including Golgi trans cisterna; basolateral plasma membrane; and brush border membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation and congenital disorder of glycosylation type IId. Orthologous to human B4GALT1 (beta-1,4-galactosyltransferase 1); PARTICIPATES IN galactose metabolic pathway; galactosemia pathway; Glut1 deficiency syndrome pathway; INTERACTS WITH 1-benzylpiperazine; 2-methoxyethanol; acetamide.

Type:

protein-coding

RefSeq Status:

VALIDATED

Also known as:

b4Gal-T1; B4galt1_mapped; beta-1,4-GalTase 1; beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase; beta4Gal-T1; Ggtb2; Glycoprotein-4-beta-galactosyltransferase 2; N-acetyllactosamine synthase; nal synthase; neolactotriaosylceramide beta-1,4-galactosyltransferase; UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 1; UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1; UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 (mapped); UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 1

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	5	55,935,614 - 55,982,461 (-)	NCBI
Rnor_6.0 Ensembl	5	57,121,769 - 57,168,610 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	5	57,121,768 - 57,168,610 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	5	61,653,278 - 61,700,179 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	58,196,388 - 58,243,231 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
Celera	5	54,547,735 - 54,594,543 (-)	NCBI		Celera
Cytogenetic Map	5	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

congenital disorder of glycosylation (ISO)

congenital disorder of glycosylation type IId (ISO)

endocrine system disease (ISS)

IgA glomerulonephritis (ISS)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-catechin (ISO)

(-)-demecolcine (ISO)

1,2-dimethylhydrazine (ISO)

1-benzylpiperazine (EXP)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

17beta-hydroxy-5alpha-androstan-3-one (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2-methoxyethanol (EXP)

4,4'-sulfonyldiphenol (ISO)

4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one (ISO)

4-nonylphenol (ISO)

4-octylphenol (ISO)

acetamide (EXP)

acetylsalicylic acid (ISO)

aflatoxin B2 (ISO)

all-trans-retinoic acid (ISO)

ammonium chloride (EXP)

antirheumatic drug (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

benzo[b]fluoranthene (ISO)

benzo[e]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

calcitriol (ISO)

captan (ISO)

carbon nanotube (ISO)

chrysene (ISO)

cobalt dichloride (ISO)

copper atom (EXP)

copper(0) (EXP)

cyclosporin A (ISO)

dexamethasone (ISO)

diazinon (ISO)

dibutyl phthalate (EXP)

diethylstilbestrol (ISO)

dopamine (EXP)

dorsomorphin (ISO)

doxorubicin (ISO)

estriol (ISO)

fenoldopam (EXP)

finasteride (EXP)

fipronil (EXP)

folic acid (ISO)

folpet (ISO)

genistein (ISO)

gentamycin (EXP)

glafenine (EXP)

keratan sulfate (ISO)

lipopolysaccharide (ISO)

lithium chloride (ISO)

malathion (ISO)

methapyrilene (ISO)

methotrexate (ISO)

methylseleninic acid (ISO)

paracetamol (ISO)

paricalcitol (ISO)

phenylmercury acetate (ISO)

phosphorus atom (ISO)

phosphorus(.) (ISO)

pirinixic acid (ISO)

pregnenolone 16alpha-carbonitrile (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

sodium dichromate (EXP,ISO)

Soman (EXP)

sulindac (EXP)

sunitinib (ISO)

tamoxifen (ISO)

testosterone (ISO)

tetraphene (ISO)

Tributyltin oxide (ISO)

trichloroethene (EXP)

tunicamycin (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

acute inflammatory response (IEA,ISO)

angiogenesis involved in wound healing (IEA,ISO)

binding of sperm to zona pellucida (IEA,ISO)

branching morphogenesis of an epithelial tube (ISO)

cell adhesion (IEA,ISO)

cell-matrix adhesion (ISO)

development of secondary sexual characteristics (IEA,ISO)

epithelial cell development (IEA,ISO)

extracellular matrix organization (IEA,ISO)

galactose metabolic process (IEA,ISO)

glycoprotein biosynthetic process (ISO)

glycosylation (IBA)

lactose biosynthetic process (IEA,ISO)

leukocyte migration (IEA,ISO)

mammary gland development (ISO)

negative regulation of cell population proliferation (IEA,ISO)

oligosaccharide biosynthetic process (ISO,TAS)

penetration of zona pellucida (IEA,ISO)

positive regulation of apoptotic process (IEA,ISO)

positive regulation of apoptotic process involved in mammary gland involution (ISO)

positive regulation of epithelial cell proliferation involved in wound healing (IEA,ISO)

protein glycosylation (ISO)

protein N-linked glycosylation (IBA,IEA,ISO)

regulation of acrosome reaction (IEA,ISO)

regulation of cell population proliferation (ISO)

regulation of cellular component movement (ISO)

response to wounding (IEP)

wound healing (ISO)

Cellular Component

basolateral plasma membrane (IEA,ISO)

brush border membrane (IEA,ISO)

cell surface (ISO)

cellular_component (ND)

desmosome (IEA,ISO)

external side of plasma membrane (IEA,ISO)

extracellular region (IEA)

filopodium (IEA)

Golgi apparatus (IBA,ISO)

Golgi cisterna membrane (IEA)

Golgi trans cisterna (IEA,ISO)

integral component of membrane (IEA)

plasma membrane (ISO)

Molecular Function

alpha-tubulin binding (ISO)

beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity (IBA,IEA,ISO)

beta-tubulin binding (ISO)

cytoskeletal protein binding (IBA,ISO)

galactosyltransferase activity (IBA,ISO)

identical protein binding (ISO)

lactose synthase activity (IEA,ISO)

laminin binding involved in cell-matrix adhesion (ISO)

manganese ion binding (IEA,ISO)

molecular_function (ND)

N-acetyllactosamine synthase activity (IEA,ISO)

protein binding (ISO)

UDP-galactosyltransferase activity (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

galactose metabolic pathway (IEA,ISO)

galactosemia pathway (ISO)

Glut1 deficiency syndrome pathway (ISO)

keratan sulfate biosynthetic pathway (IEA)

lacto-series glycosphingolipid metabolic pathway (IEA)

lactose biosynthetic pathway (ISO)

N-linked glycan biosynthetic pathway (IEA)

O-linked glycan biosynthetic pathway (IEA)

References

References - curated


1.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Hansske B, etal., J Clin Invest. 2002 Mar;109(6):725-33.
3.	Liu X, etal., Inflammation. 2012 Aug;35(4):1365-77. doi: 10.1007/s10753-012-9450-9.
4.	MGD data from the GO Consortium
5.	NCBI rat LocusLink and RefSeq merged data July 26, 2002
6.	OMIM Disease Annotation Pipeline
7.	Pipeline to import KEGG annotations from KEGG into RGD
8.	Pipeline to import SMPDB annotations from SMPDB into RGD
9.	RGD automated data pipeline
10.	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11.	RGD automated import pipeline for gene-chemical interactions
12.	RGD comprehensive gene curation
13.	Shen A, etal., Neurosci Lett 2002 Jul 12;327(1):45-8.

Additional References at PubMed

PMID:33805	PMID:1302270	PMID:2120039	PMID:2503706	PMID:3917437	PMID:6121819	PMID:7641815	PMID:7744867	PMID:8089187	PMID:8134355	PMID:8787759	PMID:8889548
PMID:9013935	PMID:9155011	PMID:9374408	PMID:9588205	PMID:9813328	PMID:10381349	PMID:10900002	PMID:11375348	PMID:11419947	PMID:11463354	PMID:11900463	PMID:12714507
PMID:15039218	PMID:15158676	PMID:15282149	PMID:16157350	PMID:16502470	PMID:17372842	PMID:17917074	PMID:18294815	PMID:18320333	PMID:18512149	PMID:18677561	PMID:19056867
PMID:19199708	PMID:19530228	PMID:19946888	PMID:21161318	PMID:21461672	PMID:21573722	PMID:22359038	PMID:22687727	PMID:22706684	PMID:23376485	PMID:23533145	PMID:24006456

Genomics

Comparative Map Data

B4galt1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	5	55,935,614 - 55,982,461 (-)	NCBI
Rnor_6.0 Ensembl	5	57,121,769 - 57,168,610 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	5	57,121,768 - 57,168,610 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	5	61,653,278 - 61,700,179 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	58,196,388 - 58,243,231 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
Celera	5	54,547,735 - 54,594,543 (-)	NCBI		Celera
Cytogenetic Map	5	q22	NCBI

B4GALT1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	9	33,104,082 - 33,167,356 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	9	33,104,077 - 33,167,336 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	9	33,104,075 - 33,167,334 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	33,100,642 - 33,157,236 (-)	NCBI	NCBI36		hg18	NCBI36
Build 34	9	33,100,641 - 33,157,231	NCBI
Celera	9	33,041,647 - 33,098,362 (-)	NCBI
Cytogenetic Map	9	p21.1	NCBI
HuRef	9	33,068,632 - 33,125,120 (-)	NCBI		HuRef
CHM1_1	9	33,110,422 - 33,167,124 (-)	NCBI		CHM1_1

B4galt1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	40,804,602 - 40,855,711 (-)	NCBI	GRCm39		mm39
GRCm39 Ensembl	4	40,804,602 - 40,854,005 (-)	Ensembl
GRCm38	4	40,804,602 - 40,853,984 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	40,804,602 - 40,854,005 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	40,751,635 - 40,801,031 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	4	40,993,273 - 41,042,669 (-)	NCBI			mm8
Celera	4	40,465,334 - 40,514,995 (-)	NCBI		Celera
Cytogenetic Map	4	A5	NCBI
cM Map	4	20.46	NCBI

B4galt1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955472	2,490,661 - 2,536,317 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955472	2,490,649 - 2,536,053 (+)	NCBI	ChiLan1.0	ChiLan1.0

B4GALT1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	9	33,697,551 - 33,754,192 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	9	33,691,733 - 33,754,192 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	9	32,889,124 - 32,945,759 (-)	NCBI	Mhudiblu_PPA_v0		panPan3

B4GALT1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	11	50,223,880 - 50,276,745 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	11	50,226,242 - 50,276,730 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	11	48,852,300 - 48,904,681 (-)	NCBI
ROS_Cfam_1.0	11	51,162,293 - 51,214,628 (-)	NCBI
UMICH_Zoey_3.1	11	49,827,305 - 49,879,364 (-)	NCBI
UNSW_CanFamBas_1.0	11	49,693,975 - 49,746,100 (-)	NCBI
UU_Cfam_GSD_1.0	11	50,459,162 - 50,511,219 (-)	NCBI

B4galt1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	165,112,211 - 165,166,434 (-)	NCBI
SpeTri2.0	NW_004936524	1,659,791 - 1,713,971 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

B4GALT1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	10	33,317,305 - 33,381,289 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	10	33,317,295 - 33,381,285 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	10	37,574,201 - 37,635,284 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LOC103219294
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	12	47,104,750 - 47,162,157 (+)	NCBI
ChlSab1.1 Ensembl	12	47,104,789 - 47,162,173 (+)	Ensembl

B4galt1
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624736	37,848,431 - 37,927,291 (-)	NCBI

Position Markers

D5Mit1

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	55,962,278 - 55,962,414 (+)	MAPPER
Rnor_6.0	5	57,148,431 - 57,148,566	NCBI	Rnor6.0
Rnor_5.0	5	61,679,937 - 61,680,072	UniSTS	Rnor5.0
RGSC_v3.4	5	58,223,050 - 58,223,186	RGD	RGSC3.4
RGSC_v3.4	5	58,223,051 - 58,223,186	UniSTS	RGSC3.4
RGSC_v3.1	5	58,223,098 - 58,223,440	RGD
Celera	5	54,574,374 - 54,574,509	UniSTS
RH 2.0 Map	5	353.9	RGD
Cytogenetic Map	5	q22	UniSTS

AU046353

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	55,978,678 - 55,978,876 (+)	MAPPER
Rnor_6.0	5	57,164,828 - 57,165,025	NCBI	Rnor6.0
Rnor_5.0	5	61,696,335 - 61,696,532	UniSTS	Rnor5.0
RGSC_v3.4	5	58,239,449 - 58,239,646	UniSTS	RGSC3.4
Celera	5	54,590,761 - 54,590,958	UniSTS
Cytogenetic Map	5	q22	UniSTS

RH142957

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	55,935,638 - 55,935,800 (+)	MAPPER
Rnor_6.0	5	57,121,793 - 57,121,954	NCBI	Rnor6.0
Rnor_5.0	5	61,653,299 - 61,653,460	UniSTS	Rnor5.0
Rnor_5.0	5	61,653,151 - 61,653,460	UniSTS	Rnor5.0
RGSC_v3.4	5	58,196,413 - 58,196,574	UniSTS	RGSC3.4
Celera	5	54,547,760 - 54,547,921	UniSTS
RH 3.4 Map	5	287.5	UniSTS
Cytogenetic Map	5	q22	UniSTS

QTLs in Region (Rnor_6.0)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1331771	Rf35	Renal function QTL 35	4.36965		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	5	1	89432042	Rat
1331756	Rf34	Renal function QTL 34	4.16275		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	5	1	93273395	Rat
70212	Niddm25	Non-insulin dependent diabetes mellitus QTL 25	3.54		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	5	1	136640934	Rat
1576314	Eutr1	Estrogen induced uterine response QTL 1			uterus integrity trait (VT:0010575)	pyometritis severity score (CMO:0002009)	5	1525098	78720537	Rat
8662454	Vetf3	Vascular elastic tissue fragility QTL 3	27.4		artery integrity trait (VT:0010639)	number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)	5	1666587	71552720	Rat
7394712	Emca13	Estrogen-induced mammary cancer QTL 13			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	9514842	103580403	Rat
634305	Mamtr1	Mammary tumor resistance QTL 1		0.0001	mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	12651967	117554267	Rat
1641903	Alcrsp3	Alcohol response QTL 3			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	5	13288888	58288888	Rat
1600358	Mamtr5	Mammary tumor resistance QTL 5			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	18847913	63847913	Rat
1358353	Srcrtb2	Stress Responsive Cort Basal QTL 2	3.48	0.003	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	5	18847913	76608178	Rat
8552954	Pigfal14	Plasma insulin-like growth factor 1 level QTL 14	9		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	21904363	66904363	Rat
1578767	Stresp17	Stress response QTL 17	4.3	0.01	blood aldosterone amount (VT:0005346)	plasma aldosterone level (CMO:0000551)	5	29078899	74078899	Rat
1578776	Stresp18	Stress response QTL 18	2.9		thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	5	29078899	74078899	Rat
6903292	Stl28	Serum triglyceride level QTL 28	2.6	0.0073	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	5	29641661	74641661	Rat
6903306	Scl35	Serum cholesterol QTL 35	2.6	0.0073	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	29641661	74641661	Rat
2290448	Scl54	Serum cholesterol level QTL 54	2.93		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	31926122	136640934	Rat
1298067	Scl15	Serum cholesterol level QTL 15	4.8	0.001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	34402409	79402409	Rat
1302786	Kidm8	Kidney mass QTL 8	28.15		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	5	34402409	79402409	Rat
1598807	Glom12	Glomerulus QTL 12	2.7		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	5	34402409	79402409	Rat
1576317	Eutr2	Estrogen induced uterine response QTL 2		0.01	uterus integrity trait (VT:0010575)	pyometritis severity score (CMO:0002009)	5	35225432	108092802	Rat
2316959	Gluco59	Glucose level QTL 59	4.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	5	35661945	117554267	Rat
1641922	Alcrsp8	Alcohol response QTL 8			alcohol metabolism trait (VT:0015089)	blood ethanol level (CMO:0000535)	5	35788756	70742105	Rat
1641912	Alcrsp18	Alcohol response QTL 18			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	5	35788756	147487820	Rat
1549845	Scl44	Serum cholesterol level QTL 44	6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	40777918	154732375	Rat
1331773	Scl26	Serum cholesterol level QTL 26	3.065		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	44404276	89432042	Rat
1331801	Rf33	Renal function QTL 33	4.149		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	5	44404276	134502294	Rat
1578766	Tcas11	Tongue tumor susceptibility QTL 11	4.12		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	5	47745646	167946134	Rat
1300115	Hrtrt7	Heart rate QTL 7	2.76		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	5	48722038	93587756	Rat
1576312	Emca8	Estrogen-induced mammary cancer QTL 8	4.1		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	51418671	147487820	Rat
9589025	Epfw7	Epididymal fat weight QTL 7	20.66	0.001	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	5	51804426	96804426	Rat
7411561	Bw134	Body weight QTL 134	24	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	51804426	96804426	Rat
2303615	Vencon7	Ventilatory control QTL 7		0.001	respiration trait (VT:0001943)	respiration rate (CMO:0000289)	5	53309568	98309568	Rat
2303574	Gluco42	Glucose level QTL 42	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	5	55903593	100903593	Rat
61359	Eaex	Experimental allergic encephalomyelitis QTL x	3		nervous system integrity trait (VT:0010566)	post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)	5	56902367	101902367	Rat
70189	Mcs5	Mammary carcinoma susceptibility QTL 5	10.51		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	56991667	137729065	Rat

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	129
Count of miRNA genes:	100
Interacting mature miRNAs:	114
Transcripts:	ENSRNOT00000010874
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	34	57	41	19	41	3	5	12	29	36	11	3
Low		9					5	6	62	6	5		5
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_053287	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039109259	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AA818683	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AA956551	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC119348	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC121205	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF102262	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AI709691	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CB736416	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CB741712	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473962	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CK364907	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000161	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000090499 ⟹ ENSRNOP00000069825

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	5	57,121,769 - 57,168,610 (-)	Ensembl

RefSeq Acc Id:

NM_053287 ⟹ NP_445739

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	5	55,935,614 - 55,982,461 (-)	NCBI
Rnor_6.0	5	57,121,768 - 57,168,610 (-)	NCBI
Rnor_5.0	5	61,653,278 - 61,700,179 (-)	NCBI
RGSC_v3.4	5	58,196,388 - 58,243,231 (-)	RGD
Celera	5	54,547,735 - 54,594,543 (-)	RGD

Sequence:

show sequence

CCTCTCGTGCCCCGCTGATCTCTCCAGAGTCCCGCGGCTGGGGGTGTCGACTTTCCGCCACAGG
CGGCCGGTGCTGCGCTAGGTCCTAGCCCTCCCCCCGGCCCCCACCCCCCGGCCCCTCCTTCCAT
CGCTGTGGTCGGGTAGCGCCTGGCGGGCGGCCTGCGGGCGGGCCGTCCTCTCAGCCGTAGCCCA
CCCCCTCTTAAAGCCGCGGCGGGAAGATGAGGTTTCGTGAGCCGTTCCTGGGCGGCAGCGCCGC
GATGCCGGGCGCGACCCTGCAGCGGGCCTGCCGCCTGCTCGTGGCGGTCTGCGCGCTGCACCTT
GGCGTCACCCTGGTCTATTACCTCTCCGGTCGCGATCTGAGCCGCCTGCCCCAACTGGTCGGAG
TCTCCTCTTCACTGCAAGGCGGCACGAACGGCGCCGCCGCCAGCAAGCAGCCCTCGGGAGAGCT
CCGGCCCCGGGGCGCGCGGCCGCCGCCTCCTTTAGGCGTCTCCCCGAAGCCTCGCCCGGGTTCT
GACTCCAGCCCTGATGCGGCTTCTGGCCCCGGCCTGAAGAGCAACTTGACTTCGGTGCCAATGC
CCACCAGCACTGGATTGTTGACTCTGCCTGCTTGCCCTGAGGAGTCCCCGCTGCTCGTTGGCCC
CATGGTGATTGACTTTAATATTCCTGTGGATCTGGAGCTTTTGGCAAAGAAGAACCCAGAGATA
AAGATGGGCGGCCGTTACTTCCCCAAGGACTGTATCTCCCCTCACAAGGTGGCCATCATTATCC
CATTCCGTAACCGGCAGGAGCACCTCAAATACTGGCTGTATTATTTGCATCCAGTCCTTCAGCG
CCAGCAACTCGACTATGGCATCTACGTCATCAATCAGGCTGGAGACACCATGTTTAATCGAGCT
AAGCTGCTCAACGTTGGCTTTCAAGAGGCCTTGAAAGACTATGACTACAACTGCTTTGTGTTCA
GTGATGTGGACCTCATTCCAATGGATGACCATAATGCCTACAGGTGCTTTTCACAGCCACGGCA
TATTTCTGTCGCAATGGACAAGTTCGGGTTTAGCCTGCCTTACGTTCAGTATTTTGGAGGTGTC
TCCGCTCTCAGTAAACAACAGTTCCTTACCATCAATGGATTTCCTAATAATTACTGGGGCTGGG
GAGGAGAAGATGATGACATTTTTAACAGATTAGTTCATAAAGGCATGTCTATATCACGCCCAAA
TGCTGTGGTAGGCAGGTGTCGCATGATCCGGCACTCAAGAGACAAGAAAAATGAGCCCAACCCT
CAGAGGTTTGACCGGATCGCACATACAAAGGAAACGATGCGCCTTGATGGTTTGAACTCACTTA
CCTACCAGGTGTTGGACATACAGAGATACCCGTTATATACCAAAATCACAGTGGACATCGGGAC
ACCAAGATAGCATTTTGGTACAAATAAGAGACCCGAGGATGGCCAGAGACCTCAGATGTGTGTC
TCTGCCAGTCGACTGGGCTGGTCCCTCTCATTTGTTCAGTCTGAATGATAGTTCTCCTTCCTTA
CCATTCAGACATCTTTCCAGATGCCCAGGGTGAATGTCACGTTTACCCACAACCTGGCTCGGCA
CTGGGTGAAATTCTACAAGGTGTTTATCAGTGTAAAAACGGTCAGCCTTTGGAGAGGTTTCTTG
GACACGTCACCCCCAAAGAGTCGGAACTGTGCCCAGCTCCAACCTTAGTGACTGTGGGTCATAG
TCCCAGTGCTGAAACTGCTGAAGTGTGACATGGGTAAGAGCTTTGCTTTAGTCGGCGATGTCCA
CACTTCATGACCAATGGAGGCTGCTGCTGGATTCGGATTCACAAGATATTCTTGCATATTTTTT
TATACAAAAAATCAAAATTTCAATCAGTCTCGTGTTCTGTCCCTTTCCTATGTCCTCTCACCGG
TATGCAACTATTACAATCACTGCGTGTGCGTCTTTTCTTAGCAAAAGAGTTTTAAAACTTGAGC
CTGGAGCTTGGTGTCCTGTGAGTGTGGCTGCCGAGGCCTTGCCCTCAGAGCAGGGGCCGGGACA
CTCACTTCCGTGACCCGTCTCCAGATCCCTGTCTGATTTCTGAATGTAAAGAGGTTTTTTGTGG
TTGTTGTTTTGTTTTGTTTTTGTTTTTAGAAGCAGTTTGTAGTATTTTAAAGAATAAATCAAGT
TTTGATTATGCTATAGGTTGATTTTTGTGTTGATCCAAATTGGAATAGCTATTGAGTGTTTTAA
GTCGTGACTTTATTTTTCTGGGCATGCTATATAAACTTGAATTTCCTATGTAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039109259 ⟹ XP_038965187

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	5	55,947,321 - 55,982,461 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_445739	(Get FASTA)	NCBI Sequence Viewer
	XP_038965187	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAD41721	(Get FASTA)	NCBI Sequence Viewer
	EDL98643	(Get FASTA)	NCBI Sequence Viewer
	EDL98644	(Get FASTA)	NCBI Sequence Viewer
	EDL98645	(Get FASTA)	NCBI Sequence Viewer
	P80225	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_445739 ⟸ NM_053287

- UniProtKB:

G3V722 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MRFREPFLGGSAAMPGATLQRACRLLVAVCALHLGVTLVYYLSGRDLSRLPQLVGVSSSLQGGT
NGAAASKQPSGELRPRGARPPPPLGVSPKPRPGSDSSPDAASGPGLKSNLTSVPMPTSTGLLTL
PACPEESPLLVGPMVIDFNIPVDLELLAKKNPEIKMGGRYFPKDCISPHKVAIIIPFRNRQEHL
KYWLYYLHPVLQRQQLDYGIYVINQAGDTMFNRAKLLNVGFQEALKDYDYNCFVFSDVDLIPMD
DHNAYRCFSQPRHISVAMDKFGFSLPYVQYFGGVSALSKQQFLTINGFPNNYWGWGGEDDDIFN
RLVHKGMSISRPNAVVGRCRMIRHSRDKKNEPNPQRFDRIAHTKETMRLDGLNSLTYQVLDIQR
YPLYTKITVDIGTPR

hide sequence

RefSeq Acc Id:

ENSRNOP00000069825 ⟸ ENSRNOT00000090499

RefSeq Acc Id:	XP_038965187 ⟸ XM_039109259
- Peptide Label:	isoform X1

Protein Domains

Glyco_transf_7C Glyco_transf_7N

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13693637

Promoter ID:

EPDNEW_R4161

Type:

multiple initiation site

Name:

B4galt1_1

Description:

beta-1,4-galactosyltransferase 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	57,168,585 - 57,168,645	EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)

ACI/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

ACI/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

ACI/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

BBDP/Wor (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

BN/SsN (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Buf/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

COP/CrCrl (MCW & UW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob) University of Wisconsin (Dr. James Shull)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Charles River Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)

F344/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

F344/NRrrc (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

FHH/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHH/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

FHL/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHL/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

GH/OmrMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

GK/Ox (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LE/Stm (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/Crl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/NCrlBR (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LH/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LL/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LN/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

M520/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

MHS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MNS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MR/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

SBH/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBH/Ygl sequenced by MCW

SBH/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SBN/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBN/Ygl sequenced by MCW

SBN/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHR/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHRSP/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SR/JrHsd (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Harlan Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SR/JrHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/Jr (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/JrHsdMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SS/JrHsdMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WAG/Rij (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

WKY/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WN/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:620900	AgrOrtholog
Ensembl Genes	ENSRNOG00000059461	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000069825	ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000090499	ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH	3.90.550.10	UniProtKB/TrEMBL
InterPro	Galactosyl_T_2_met	UniProtKB/TrEMBL
	Galactosyl_T_C	UniProtKB/TrEMBL
	Glyco_transf_7N	UniProtKB/TrEMBL
	Nucleotide-diphossugar_trans	UniProtKB/TrEMBL
KEGG Report	rno:24390	UniProtKB/TrEMBL
NCBI Gene	24390	ENTREZGENE
PANTHER	Galactosyl_T_2	UniProtKB/TrEMBL
Pfam	Galactosyl_T_2	UniProtKB/TrEMBL
	Glyco_transf_7N	UniProtKB/TrEMBL
PhenoGen	B4galt1	PhenoGen
PRINTS	B14GALTRFASE	UniProtKB/TrEMBL
Superfamily-SCOP	SSF53448	UniProtKB/TrEMBL
UniProt	B4GT1_RAT	UniProtKB/Swiss-Prot
	G3V722	ENTREZGENE, UniProtKB/TrEMBL
	P80225	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-03-22	B4galt1	beta-1,4-galactosyltransferase 1	B4galt1	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	B4galt1	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1	B4galt1_predicted	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1	'predicted' is removed	2292626	APPROVED
2007-04-13	B4galt1_predicted	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1	B4galt1_mapped	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 (mapped)	Symbol and Name updated	737654	APPROVED
2007-02-02	B4galt1_mapped	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 (mapped)	B4galt1	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 (mapped)	Data Merged	737654	APPROVED
2006-11-19	B4galt1	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 (mapped)			Symbol and Name status set to provisional	70820	PROVISIONAL
2005-11-17	B4galt1_mapped	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 (mapped)			Symbol and Name updated	1556543	APPROVED
2003-04-09	B4galt1	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1			Symbol and Name updated	629477	APPROVED
2003-03-07	B4galt1	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1	Ggtb2	Glycoprotein-4-beta-galactosyltransferase 2	Data Merged	628472	PROVISIONAL
2002-08-07	B4galt1				Symbol and Name status set to provisional	70820	PROVISIONAL
2002-06-10	Ggtb2	Glycoprotein-4-beta-galactosyltransferase 2			Symbol and Name status set to approved	70586	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB

Imported Annotations - KEGG (archival)