B4galt1 (beta-1,4-galactosyltransferase 1) - Rat Genome Database

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Gene: B4galt1 (beta-1,4-galactosyltransferase 1) Rattus norvegicus
Analyze
Symbol: B4galt1
Name: beta-1,4-galactosyltransferase 1
RGD ID: 620900
Description: Predicted to enable several functions, including UDP-galactosyltransferase activity; laminin binding activity involved in cell-matrix adhesion; and tubulin binding activity. Involved in response to wounding. Predicted to be located in several cellular components, including Golgi trans cisterna; basolateral plasma membrane; and brush border membrane. Predicted to be part of protein-containing complex. Predicted to be active in Golgi apparatus and plasma membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation and congenital disorder of glycosylation type IId. Orthologous to human B4GALT1 (beta-1,4-galactosyltransferase 1); PARTICIPATES IN galactose metabolic pathway; galactosemia pathway; Glut1 deficiency syndrome pathway; INTERACTS WITH 1-benzylpiperazine; 2-methoxyethanol; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: b4Gal-T1; B4galt1_mapped; beta-1,4-GalTase 1; beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase; beta4Gal-T1; Ggtb2; Glycoprotein-4-beta-galactosyltransferase 2; N-acetyllactosamine synthase; nal synthase; neolactotriaosylceramide beta-1,4-galactosyltransferase; UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 1; UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1; UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 (mapped); UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2555,935,614 - 55,982,461 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl555,935,615 - 55,982,461 (-)Ensembl
Rnor_6.0557,121,768 - 57,168,610 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl557,121,769 - 57,168,610 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0561,653,278 - 61,700,179 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4558,196,388 - 58,243,231 (-)NCBIRGSC3.4rn4RGSC3.4
Celera554,547,735 - 54,594,543 (-)NCBICelera
Cytogenetic Map5q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(-)-demecolcine  (ISO)
1,2-dimethylhydrazine  (ISO)
1-benzylpiperazine  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2-methoxyethanol  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (ISO)
4-nonylphenol  (ISO)
4-octylphenol  (ISO)
acetamide  (EXP)
acetylsalicylic acid  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
benzo[e]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
calcitriol  (ISO)
captan  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chrysene  (ISO)
cobalt dichloride  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
cyclosporin A  (ISO)
dexamethasone  (ISO)
diazinon  (ISO)
dibutyl phthalate  (EXP)
diethylstilbestrol  (ISO)
dopamine  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
estriol  (ISO)
fenoldopam  (EXP)
fenthion  (ISO)
finasteride  (EXP)
fipronil  (EXP)
folic acid  (ISO)
folpet  (ISO)
genistein  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
ivermectin  (ISO)
keratan sulfate  (ISO)
lipopolysaccharide  (ISO)
lithium chloride  (ISO)
malathion  (ISO)
methapyrilene  (ISO)
methotrexate  (ISO)
methylseleninic acid  (ISO)
paracetamol  (ISO)
paricalcitol  (ISO)
phenylmercury acetate  (ISO)
phosphorus atom  (ISO)
phosphorus(.)  (ISO)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium dichromate  (EXP,ISO)
Soman  (EXP)
sulindac  (EXP)
sunitinib  (ISO)
tamoxifen  (ISO)
testosterone  (ISO)
tetraphene  (ISO)
Tributyltin oxide  (ISO)
trichloroethene  (EXP)
Triptolide  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
acute inflammatory response  (IEA,ISO)
angiogenesis involved in wound healing  (IEA,ISO)
apoptotic process involved in mammary gland involution  (ISO)
binding of sperm to zona pellucida  (IEA,ISO)
branching morphogenesis of an epithelial tube  (ISO)
carbohydrate metabolic process  (IEA)
cell adhesion  (IEA,ISO)
cell population proliferation  (ISO)
cell-matrix adhesion  (ISO)
development of secondary sexual characteristics  (IEA,ISO)
epithelial cell development  (IEA,ISO)
epithelial cell proliferation  (IEA,ISO)
extracellular matrix organization  (IEA,ISO)
galactose metabolic process  (IEA,ISO)
glycoprotein biosynthetic process  (ISO)
glycosylation  (IBA)
lactose biosynthetic process  (IEA,ISO)
leukocyte migration  (ISO)
lipid metabolic process  (IEA)
macrophage migration  (IEA,ISO)
mammary gland development  (ISO)
negative regulation of cell population proliferation  (ISO)
negative regulation of epithelial cell proliferation  (IEA,ISO)
obsolete regulation of cellular component movement  (ISO)
oligosaccharide biosynthetic process  (ISO,TAS)
penetration of zona pellucida  (IEA,ISO)
positive regulation of apoptotic process  (IEA,ISO)
positive regulation of apoptotic process involved in mammary gland involution  (ISO)
positive regulation of epithelial cell proliferation involved in wound healing  (IEA,ISO)
protein glycosylation  (IEA,ISO)
protein N-linked glycosylation  (IBA,IEA,ISO)
regulation of acrosome reaction  (IEA,ISO)
regulation of cell population proliferation  (ISO)
response to wounding  (IEP)
wound healing  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Deficiency of UDP-galactose:N-acetylglucosamine beta-1,4-galactosyltransferase I causes the congenital disorder of glycosylation type IId. Hansske B, etal., J Clin Invest. 2002 Mar;109(6):725-33.
3. The functional interaction between CDK11p58 and beta-1,4-galactosyltransferase I involved in astrocyte activation caused by lipopolysaccharide. Liu X, etal., Inflammation. 2012 Aug;35(4):1365-77. doi: 10.1007/s10753-012-9450-9.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
9. GOA pipeline RGD automated data pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Comprehensive gene review and curation RGD comprehensive gene curation
13. Expression of beta-1,4-galactosyltransferase II and V in rat injured sciatic nerves. Shen A, etal., Neurosci Lett 2002 Jul 12;327(1):45-8.
Additional References at PubMed
PMID:33805   PMID:1302270   PMID:2120039   PMID:2503706   PMID:3917437   PMID:6121819   PMID:7641815   PMID:7744867   PMID:8089187   PMID:8134355   PMID:8787759   PMID:8889548  
PMID:9013935   PMID:9155011   PMID:9374408   PMID:9588205   PMID:9813328   PMID:10381349   PMID:10900002   PMID:11375348   PMID:11419947   PMID:11463354   PMID:11900463   PMID:12714507  
PMID:15039218   PMID:15158676   PMID:15282149   PMID:16157350   PMID:16502470   PMID:17372842   PMID:17917074   PMID:18294815   PMID:18320333   PMID:18512149   PMID:18677561   PMID:19056867  
PMID:19199708   PMID:19530228   PMID:19946888   PMID:21161318   PMID:21461672   PMID:21573722   PMID:22359038   PMID:22687727   PMID:22706684   PMID:23376485   PMID:23533145   PMID:24006456  


Genomics

Comparative Map Data
B4galt1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2555,935,614 - 55,982,461 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl555,935,615 - 55,982,461 (-)Ensembl
Rnor_6.0557,121,768 - 57,168,610 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl557,121,769 - 57,168,610 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0561,653,278 - 61,700,179 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4558,196,388 - 58,243,231 (-)NCBIRGSC3.4rn4RGSC3.4
Celera554,547,735 - 54,594,543 (-)NCBICelera
Cytogenetic Map5q22NCBI
B4GALT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38933,104,077 - 33,185,089 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl933,104,082 - 33,167,356 (-)EnsemblGRCh38hg38GRCh38
GRCh37933,104,075 - 33,167,334 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36933,100,642 - 33,157,236 (-)NCBINCBI36hg18NCBI36
Build 34933,100,641 - 33,157,231NCBI
Celera933,041,647 - 33,098,362 (-)NCBI
Cytogenetic Map9p21.1NCBI
HuRef933,068,632 - 33,125,120 (-)NCBIHuRef
CHM1_1933,110,422 - 33,167,124 (-)NCBICHM1_1
T2T-CHM13v2.0933,120,636 - 33,185,969 (-)NCBI
B4galt1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39440,804,602 - 40,855,711 (-)NCBIGRCm39mm39
GRCm39 Ensembl440,804,602 - 40,854,005 (-)Ensembl
GRCm38440,804,602 - 40,853,984 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl440,804,602 - 40,854,005 (-)EnsemblGRCm38mm10GRCm38
MGSCv37440,751,635 - 40,801,031 (-)NCBIGRCm37mm9NCBIm37
MGSCv36440,993,273 - 41,042,669 (-)NCBImm8
Celera440,465,334 - 40,514,995 (-)NCBICelera
Cytogenetic Map4A5NCBI
cM Map420.46NCBI
B4galt1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554722,490,661 - 2,536,317 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554722,490,649 - 2,536,053 (+)NCBIChiLan1.0ChiLan1.0
B4GALT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1933,697,551 - 33,754,192 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl933,691,733 - 33,754,192 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0932,889,124 - 32,945,759 (-)NCBIMhudiblu_PPA_v0panPan3
B4GALT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11150,223,880 - 50,276,745 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1150,226,242 - 50,276,730 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1148,852,300 - 48,904,681 (-)NCBI
ROS_Cfam_1.01151,162,293 - 51,214,628 (-)NCBI
ROS_Cfam_1.0 Ensembl1151,144,069 - 51,214,773 (-)Ensembl
UMICH_Zoey_3.11149,827,305 - 49,879,364 (-)NCBI
UNSW_CanFamBas_1.01149,693,975 - 49,746,100 (-)NCBI
UU_Cfam_GSD_1.01150,459,162 - 50,511,219 (-)NCBI
B4galt1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947165,112,211 - 165,166,434 (-)NCBI
SpeTri2.0NW_0049365241,659,791 - 1,713,971 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
B4GALT1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1033,317,305 - 33,381,285 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11033,317,295 - 33,381,285 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21037,574,201 - 37,635,284 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103219294
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11247,104,750 - 47,162,157 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1247,104,789 - 47,162,173 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366703211,002 - 21,137 (+)NCBIVero_WHO_p1.0
B4galt1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473637,848,117 - 37,927,980 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462473637,848,431 - 37,927,291 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
D5Mit1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2555,962,278 - 55,962,414 (+)MAPPERmRatBN7.2
Rnor_6.0557,148,431 - 57,148,566NCBIRnor6.0
Rnor_5.0561,679,937 - 61,680,072UniSTSRnor5.0
RGSC_v3.4558,223,050 - 58,223,186RGDRGSC3.4
RGSC_v3.4558,223,051 - 58,223,186UniSTSRGSC3.4
RGSC_v3.1558,223,098 - 58,223,440RGD
Celera554,574,374 - 54,574,509UniSTS
RH 2.0 Map5353.9RGD
Cytogenetic Map5q22UniSTS
AU046353  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2555,978,678 - 55,978,876 (+)MAPPERmRatBN7.2
Rnor_6.0557,164,828 - 57,165,025NCBIRnor6.0
Rnor_5.0561,696,335 - 61,696,532UniSTSRnor5.0
RGSC_v3.4558,239,449 - 58,239,646UniSTSRGSC3.4
Celera554,590,761 - 54,590,958UniSTS
Cytogenetic Map5q22UniSTS
RH142957  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2555,935,638 - 55,935,800 (+)MAPPERmRatBN7.2
Rnor_6.0557,121,793 - 57,121,954NCBIRnor6.0
Rnor_5.0561,653,299 - 61,653,460UniSTSRnor5.0
Rnor_5.0561,653,151 - 61,653,460UniSTSRnor5.0
RGSC_v3.4558,196,413 - 58,196,574UniSTSRGSC3.4
Celera554,547,760 - 54,547,921UniSTS
RH 3.4 Map5287.5UniSTS
Cytogenetic Map5q22UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)5190450412Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51131345958Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)572947086724018Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
8662454Vetf3Vascular elastic tissue fragility QTL 327.4artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)5228222669540447Rat
7394712Emca13Estrogen-induced mammary cancer QTL 13mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)5982326699753708Rat
1641903Alcrsp3Alcohol response QTL 3response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)51268928557689285Rat
634305Mamtr1Mammary tumor resistance QTL 10.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)512789751113558310Rat
1600358Mamtr5Mammary tumor resistance QTL 5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)51887394763873947Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)51887394774251464Rat
8552954Pigfal14Plasma insulin-like growth factor 1 level QTL 149blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)52122674466226744Rat
1578767Stresp17Stress response QTL 174.30.01blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)52795544072955440Rat
1578776Stresp18Stress response QTL 182.9thymus mass (VT:0004954)thymus wet weight (CMO:0000855)52795544072955440Rat
6903292Stl28Serum triglyceride level QTL 282.60.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)52851548973515489Rat
6903306Scl35Serum cholesterol QTL 352.60.0073blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)52851548973515489Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)531663789131345958Rat
1598807Glom12Glomerulus QTL 122.7kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)53321566578215665Rat
1298067Scl15Serum cholesterol level QTL 154.80.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53321566578215665Rat
1302786Kidm8Kidney mass QTL 828.15kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)53321566578215665Rat
1576317Eutr2Estrogen induced uterine response QTL 20.01uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)534730116104251008Rat
2316959Gluco59Glucose level QTL 594.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)534944474113558310Rat
1641922Alcrsp8Alcohol response QTL 8alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)53518915368564008Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)535189153141643988Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
1331773Scl26Serum cholesterol level QTL 263.065blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)54372665686724018Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)543726656129132602Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
1300115Hrtrt7Heart rate QTL 72.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)54786906290099692Rat
9589025Epfw7Epididymal fat weight QTL 720.660.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)54946360094463600Rat
7411561Bw134Body weight QTL 134240.001body mass (VT:0001259)body weight gain (CMO:0000420)54946360094463600Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)550328551141643988Rat
2303615Vencon7Ventilatory control QTL 70.001respiration trait (VT:0001943)respiration rate (CMO:0000289)55098389595983895Rat
2303574Gluco42Glucose level QTL 422blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)55349671998496719Rat
61359EaexExperimental allergic encephalomyelitis QTL x3nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)555715622100715622Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555805606132207589Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:129
Count of miRNA genes:100
Interacting mature miRNAs:114
Transcripts:ENSRNOT00000010874
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 34 57 41 19 41 3 5 12 29 36 11 3
Low 9 5 6 62 6 5 5
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000090499   ⟹   ENSRNOP00000069825
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl555,935,615 - 55,982,461 (-)Ensembl
Rnor_6.0 Ensembl557,121,769 - 57,168,610 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000112021   ⟹   ENSRNOP00000086535
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl555,938,802 - 55,982,461 (-)Ensembl
RefSeq Acc Id: NM_053287   ⟹   NP_445739
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2555,935,614 - 55,982,461 (-)NCBI
Rnor_6.0557,121,768 - 57,168,610 (-)NCBI
Rnor_5.0561,653,278 - 61,700,179 (-)NCBI
RGSC_v3.4558,196,388 - 58,243,231 (-)RGD
Celera554,547,735 - 54,594,543 (-)RGD
Sequence:
RefSeq Acc Id: XM_039109259   ⟹   XP_038965187
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2555,947,321 - 55,982,461 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_445739   ⟸   NM_053287
- UniProtKB: G3V722 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000069825   ⟸   ENSRNOT00000090499
RefSeq Acc Id: XP_038965187   ⟸   XM_039109259
- Peptide Label: isoform X1
RefSeq Acc Id: ENSRNOP00000086535   ⟸   ENSRNOT00000112021
Protein Domains
Glyco_transf_7C   Glyco_transf_7N

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693637
Promoter ID:EPDNEW_R4161
Type:multiple initiation site
Name:B4galt1_1
Description:beta-1,4-galactosyltransferase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0557,168,585 - 57,168,645EPDNEW

Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620900 AgrOrtholog
BioCyc Gene G2FUF-41586 BioCyc
Ensembl Genes ENSRNOG00000059461 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000069825 ENTREZGENE
  ENSRNOP00000069825.1 UniProtKB/TrEMBL
  ENSRNOP00000086535.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000090499 ENTREZGENE
  ENSRNOT00000090499.2 UniProtKB/TrEMBL
  ENSRNOT00000112021.1 UniProtKB/TrEMBL
Gene3D-CATH 3.90.550.10 UniProtKB/TrEMBL
InterPro Galactosyl_T_2_met UniProtKB/TrEMBL
  Galactosyl_T_C UniProtKB/TrEMBL
  Glyco_transf_7N UniProtKB/TrEMBL
  Nucleotide-diphossugar_trans UniProtKB/TrEMBL
KEGG Report rno:24390 UniProtKB/TrEMBL
NCBI Gene 24390 ENTREZGENE
PANTHER Galactosyl_T_2 UniProtKB/TrEMBL
Pfam Galactosyl_T_2 UniProtKB/TrEMBL
  Glyco_transf_7N UniProtKB/TrEMBL
PhenoGen B4galt1 PhenoGen
PRINTS B14GALTRFASE UniProtKB/TrEMBL
Superfamily-SCOP SSF53448 UniProtKB/TrEMBL
UniProt A0A8I6A607_RAT UniProtKB/TrEMBL
  B4GT1_RAT UniProtKB/Swiss-Prot
  G3V722 ENTREZGENE, UniProtKB/TrEMBL
  P80225 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-22 B4galt1  beta-1,4-galactosyltransferase 1  B4galt1  UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 B4galt1  UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1  B4galt1_predicted  UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1  'predicted' is removed 2292626 APPROVED
2007-04-13 B4galt1_predicted  UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1  B4galt1_mapped  UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 (mapped)  Symbol and Name updated 737654 APPROVED
2007-02-02 B4galt1_mapped  UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 (mapped)  B4galt1  UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 (mapped)  Data Merged 737654 APPROVED
2006-11-19 B4galt1  UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 (mapped)      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-11-17 B4galt1_mapped  UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 (mapped)      Symbol and Name updated 1556543 APPROVED
2003-04-09 B4galt1  UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1      Symbol and Name updated 629477 APPROVED
2003-03-07 B4galt1  UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1  Ggtb2  Glycoprotein-4-beta-galactosyltransferase 2  Data Merged 628472 PROVISIONAL
2002-08-07 B4galt1        Symbol and Name status set to provisional 70820 PROVISIONAL
2002-06-10 Ggtb2  Glycoprotein-4-beta-galactosyltransferase 2      Symbol and Name status set to approved 70586 APPROVED