Gene: Ptpn3 (protein tyrosine phosphatase, non-receptor type 3) Rattus norvegicus
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Symbol: Ptpn3
Name: protein tyrosine phosphatase, non-receptor type 3
Description: ENCODES a protein that exhibits ATPase binding (ortholog); phosphotyrosine residue binding (ortholog); protein tyrosine phosphatase activity (ortholog); INVOLVED IN liver regeneration; negative regulation of membrane protein ectodomain proteolysis (ortholog); negative regulation of mitotic cell cycle (ortholog); ASSOCIATED WITH prostate cancer (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic side of plasma membrane (ortholog); INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil
AGR Description: Predicted to have several functions, including ATPase binding activity, phosphotyrosine residue binding activity, and protein tyrosine phosphatase activity; involved in liver regeneration; predicted to localize to the cytoplasm and cytoplasmic side of plasma membrane; orthologous to human PTPN3 (protein tyrosine phosphatase, non-receptor type 3).
Merged Description: Predicted to have several functions, including ATPase binding activity, phosphotyrosine residue binding activity, and protein tyrosine phosphatase activity; involved in liver regeneration; predicted to localize to the cytoplasm and cytoplasmic side of plasma membrane; orthologous to human PTPN3 (protein tyrosine phosphatase, non-receptor type 3); INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC362524; tyrosine-protein phosphatase non-receptor type 3
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0574,248,996 - 74,368,167 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0578,399,259 - 78,528,991 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4575,106,880 - 75,222,735 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1575,111,995 - 75,139,197 (-)NCBI
Celera570,758,167 - 70,876,826 (-)NCBICelera
Cytogenetic Map5q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Ptpn3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1311363
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.