Clta (clathrin, light chain A) - Rat Genome Database

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Gene: Clta (clathrin, light chain A) Rattus norvegicus
Analyze
Symbol: Clta
Name: clathrin, light chain A
RGD ID: 70919
Description: Enables GTPase binding activity and peptide binding activity. Involved in endocytosis. Located in clathrin-coated pit and clathrin-coated vesicle. Part of clathrin coat. Is active in presynaptic endocytic zone membrane and synaptic vesicle membrane. Orthologous to human CLTA (clathrin light chain A); PARTICIPATES IN Arf family mediated signaling pathway; clathrin-dependent synaptic vesicle endocytosis; endocytosis pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-amino-2-deoxy-D-glucopyranose; aconitine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: clathrin light chain; clathrin light chain A; clathrin, light chain (Lca); clathrin, light polypeptide (Lca); lca; LCA1; LCA2; LCA3; MGC105384
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2558,244,253 - 58,263,480 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl558,245,442 - 58,263,472 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx560,227,391 - 60,245,248 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0562,046,199 - 62,064,056 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0562,015,336 - 62,033,490 (+)NCBIRnor_WKY
Rnor_6.0559,490,689 - 59,509,139 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl559,491,096 - 59,509,138 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0564,012,881 - 64,031,657 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4560,484,437 - 60,502,432 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1560,484,615 - 60,502,611 (+)NCBI
Celera556,823,904 - 56,841,911 (+)NCBICelera
Cytogenetic Map5q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Epsin binds to clathrin by associating directly with the clathrin-terminal domain. Evidence for cooperative binding through two discrete sites. Drake MT, etal., J Biol Chem. 2000 Mar 3;275(9):6479-89.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Non-stoichiometric relationship between clathrin heavy and light chains revealed by quantitative comparative proteomics of clathrin-coated vesicles from brain and liver. Girard M, etal., Mol Cell Proteomics. 2005 Aug;4(8):1145-54. Epub 2005 Jun 2.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
6. Clathrin light chains LCA and LCB are similar, polymorphic, and share repeated heptad motifs. Kirchhausen T, etal., Science 1987 Apr 17;236(4799):320-4.
7. A Bcl-xL-Drp1 complex regulates synaptic vesicle membrane dynamics during endocytosis. Li H, etal., Nat Cell Biol. 2013 Jul;15(7):773-85. doi: 10.1038/ncb2791. Epub 2013 Jun 23.
8. Clathrin-coated vesicles in nervous tissue are involved primarily in synaptic vesicle recycling. Maycox PR, etal., J Cell Biol. 1992 Sep;118(6):1379-88.
9. Gene Data Set MGD Curation, June 12, 2002
10. Monitoring clathrin-mediated endocytosis during synaptic activity. Mueller VJ, etal., J Neurosci. 2004 Feb 25;24(8):2004-12.
11. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
12. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
13. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
14. A motif in the clathrin heavy chain required for the Hsc70/auxilin uncoating reaction. Rapoport I, etal., Mol Biol Cell. 2008 Jan;19(1):405-13. Epub 2007 Oct 31.
15. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
16. Comprehensive gene review and curation RGD comprehensive gene curation
17. The NECAP PHear domain increases clathrin accessory protein binding potential. Ritter B, etal., EMBO J. 2007 Sep 19;26(18):4066-77. Epub 2007 Aug 30.
18. Synaptic vesicle endocytosis. Saheki Y and De Camilli P, Cold Spring Harb Perspect Biol. 2012 Sep 1;4(9):a005645. doi: 10.1101/cshperspect.a005645.
19. Possible involvement of clathrin in neuritogenesis induced by a protease inhibitor (benzyloxycarbonyl-Leu-Leu-Leu-aldehyde) in PC12 cells. Saito Y, etal., J Biochem. 1992 Oct;112(4):448-55.
Additional References at PubMed
PMID:4066749   PMID:8413590   PMID:9188501   PMID:10908605   PMID:11382783   PMID:11756460   PMID:12234931   PMID:12477932   PMID:16025302   PMID:16854843   PMID:17228368   PMID:17880892  
PMID:19144635   PMID:19946888   PMID:20231386   PMID:20730103   PMID:22871113   PMID:25002582   PMID:25427558   PMID:29476059   PMID:31672988  


Genomics

Comparative Map Data
Clta
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2558,244,253 - 58,263,480 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl558,245,442 - 58,263,472 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx560,227,391 - 60,245,248 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0562,046,199 - 62,064,056 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0562,015,336 - 62,033,490 (+)NCBIRnor_WKY
Rnor_6.0559,490,689 - 59,509,139 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl559,491,096 - 59,509,138 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0564,012,881 - 64,031,657 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4560,484,437 - 60,502,432 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1560,484,615 - 60,502,611 (+)NCBI
Celera556,823,904 - 56,841,911 (+)NCBICelera
Cytogenetic Map5q22NCBI
CLTA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38936,190,874 - 36,212,059 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl936,190,856 - 36,304,781 (+)EnsemblGRCh38hg38GRCh38
GRCh37936,190,918 - 36,212,056 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36936,180,892 - 36,202,056 (+)NCBINCBI36Build 36hg18NCBI36
Build 34936,180,988 - 36,202,055NCBI
Celera936,124,438 - 36,145,644 (+)NCBICelera
Cytogenetic Map9p13.3NCBI
HuRef936,144,777 - 36,166,054 (+)NCBIHuRef
CHM1_1936,191,259 - 36,212,465 (+)NCBICHM1_1
T2T-CHM13v2.0936,212,927 - 36,234,065 (+)NCBIT2T-CHM13v2.0
Clta
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39444,003,816 - 44,032,846 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl444,004,452 - 44,032,846 (+)EnsemblGRCm39 Ensembl
GRCm38444,003,816 - 44,032,846 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl444,004,452 - 44,032,846 (+)EnsemblGRCm38mm10GRCm38
MGSCv37444,025,515 - 44,045,718 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36444,033,784 - 44,053,946 (+)NCBIMGSCv36mm8
Celera444,033,842 - 44,054,042 (+)NCBICelera
Cytogenetic Map4B1NCBI
Clta
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547297,235 - 117,144 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495547296,958 - 117,230 (-)NCBIChiLan1.0ChiLan1.0
CLTA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1936,841,477 - 36,862,528 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl936,840,868 - 36,862,528 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0936,040,566 - 36,061,744 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
CLTA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11152,636,328 - 52,681,258 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1152,615,039 - 52,681,270 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1151,227,019 - 51,271,906 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01153,742,643 - 53,787,381 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1153,765,885 - 53,789,703 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11152,245,564 - 52,290,214 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01152,267,619 - 52,312,459 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01152,969,170 - 53,014,020 (+)NCBIUU_Cfam_GSD_1.0
Clta
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947167,622,904 - 167,644,372 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365244,169,732 - 4,191,951 (+)EnsemblSpeTri2.0
SpeTri2.0NW_0049365244,170,425 - 4,191,951 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CLTA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1236,971,505 - 237,001,731 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11236,971,317 - 236,993,291 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21264,772,770 - 264,783,359 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CLTA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11244,346,169 - 44,367,626 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1244,344,395 - 44,367,619 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603841,437,200 - 41,458,568 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Clta
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248684,419,554 - 4,443,477 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248684,419,554 - 4,443,475 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Clta
106 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:108
Count of miRNA genes:45
Interacting mature miRNAs:54
Transcripts:ENSRNOT00000019737, ENSRNOT00000036366
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)5190450412Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51131345958Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)572947086724018Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
8662454Vetf3Vascular elastic tissue fragility QTL 327.4artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)5228222669540447Rat
7394712Emca13Estrogen-induced mammary cancer QTL 13mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)5982326699753708Rat
634305Mamtr1Mammary tumor resistance QTL 10.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)512789751113558310Rat
1600358Mamtr5Mammary tumor resistance QTL 5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)51887394763873947Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)51887394774251464Rat
8552954Pigfal14Plasma insulin-like growth factor 1 level QTL 149blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)52122674466226744Rat
1578767Stresp17Stress response QTL 174.30.01blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)52795544072955440Rat
1578776Stresp18Stress response QTL 182.9thymus mass (VT:0004954)thymus wet weight (CMO:0000855)52795544072955440Rat
6903292Stl28Serum triglyceride level QTL 282.60.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)52851548973515489Rat
6903306Scl35Serum cholesterol QTL 352.60.0073blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)52851548973515489Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)531663789131345958Rat
1598807Glom12Glomerulus QTL 122.7kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)53321566578215665Rat
1298067Scl15Serum cholesterol level QTL 154.80.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53321566578215665Rat
1302786Kidm8Kidney mass QTL 828.15kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)53321566578215665Rat
1576317Eutr2Estrogen induced uterine response QTL 20.01uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)534730116104251008Rat
2316959Gluco59Glucose level QTL 594.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)534944474113558310Rat
1641922Alcrsp8Alcohol response QTL 8alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)53518915368564008Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)535189153141643988Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
1331773Scl26Serum cholesterol level QTL 263.065blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)54372665686724018Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)543726656129132602Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
1300115Hrtrt7Heart rate QTL 72.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)54786906290099692Rat
9589025Epfw7Epididymal fat weight QTL 720.660.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)54946360094463600Rat
7411561Bw134Body weight QTL 134240.001body mass (VT:0001259)body weight gain (CMO:0000420)54946360094463600Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)550328551141643988Rat
2303615Vencon7Ventilatory control QTL 70.001respiration trait (VT:0001943)respiration rate (CMO:0000289)55098389595983895Rat
2303574Gluco42Glucose level QTL 422blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)55349671998496719Rat
61359EaexExperimental allergic encephalomyelitis QTL x3nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)555715622100715622Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555805606132207589Rat

Markers in Region
BI282730  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2558,263,218 - 58,263,407 (+)MAPPERmRatBN7.2
Rnor_6.0559,508,878 - 59,509,066NCBIRnor6.0
Rnor_5.0564,031,396 - 64,031,584UniSTSRnor5.0
RGSC_v3.4560,502,179 - 60,502,367UniSTSRGSC3.4
Celera556,841,658 - 56,841,846UniSTS
Cytogenetic Map5q22UniSTS
AV026556  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2558,263,354 - 58,263,444 (+)MAPPERmRatBN7.2
Rnor_6.0559,509,014 - 59,509,103NCBIRnor6.0
Rnor_5.0564,031,532 - 64,031,621UniSTSRnor5.0
RGSC_v3.4560,502,315 - 60,502,404UniSTSRGSC3.4
Celera556,841,794 - 56,841,883UniSTS
Cytogenetic Map5q22UniSTS
RH79677  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2558,263,164 - 58,263,443 (+)MAPPERmRatBN7.2
Rnor_6.0559,508,824 - 59,509,102NCBIRnor6.0
Rnor_5.0564,031,342 - 64,031,620UniSTSRnor5.0
RGSC_v3.4560,502,125 - 60,502,403UniSTSRGSC3.4
Celera556,841,604 - 56,841,882UniSTS
Cytogenetic Map5q22UniSTS
RH74929  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2558,263,201 - 58,263,434 (+)MAPPERmRatBN7.2
Rnor_6.0559,508,861 - 59,509,093NCBIRnor6.0
Rnor_5.0564,031,379 - 64,031,611UniSTSRnor5.0
RGSC_v3.4560,502,162 - 60,502,394UniSTSRGSC3.4
Celera556,841,641 - 56,841,873UniSTS
Cytogenetic Map5q22UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000019737   ⟹   ENSRNOP00000019737
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl558,245,467 - 58,263,472 (+)Ensembl
Rnor_6.0 Ensembl559,491,096 - 59,509,138 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000036366   ⟹   ENSRNOP00000035138
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl558,245,442 - 58,263,472 (+)Ensembl
Rnor_6.0 Ensembl559,491,103 - 59,509,131 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000083068   ⟹   ENSRNOP00000070814
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl558,245,474 - 58,263,472 (+)Ensembl
Rnor_6.0 Ensembl559,491,136 - 59,509,131 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000101159   ⟹   ENSRNOP00000089530
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl558,245,467 - 58,263,472 (+)Ensembl
RefSeq Acc Id: NM_031974   ⟹   NP_114180
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2558,245,475 - 58,263,472 (+)NCBI
Rnor_6.0559,491,136 - 59,509,131 (+)NCBI
Rnor_5.0564,012,881 - 64,031,657 (+)NCBI
RGSC_v3.4560,484,437 - 60,502,432 (+)RGD
Celera556,823,904 - 56,841,911 (+)RGD
Sequence:
RefSeq Acc Id: XM_006238104   ⟹   XP_006238166
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2558,244,253 - 58,263,480 (+)NCBI
Rnor_6.0559,490,689 - 59,509,139 (+)NCBI
Rnor_5.0564,012,881 - 64,031,657 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006238105   ⟹   XP_006238167
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2558,244,253 - 58,263,480 (+)NCBI
Rnor_6.0559,490,689 - 59,509,139 (+)NCBI
Rnor_5.0564,012,881 - 64,031,657 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006238106   ⟹   XP_006238168
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2558,244,253 - 58,263,480 (+)NCBI
Rnor_6.0559,490,689 - 59,509,139 (+)NCBI
Rnor_5.0564,012,881 - 64,031,657 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_114180   ⟸   NM_031974
- UniProtKB: P08081 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006238166   ⟸   XM_006238104
- Peptide Label: isoform X1
- UniProtKB: P08081 (UniProtKB/Swiss-Prot),   A0A0G2JYW3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006238167   ⟸   XM_006238105
- Peptide Label: isoform X2
- UniProtKB: A0A8I6A7H3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006238168   ⟸   XM_006238106
- Peptide Label: isoform X3
- UniProtKB: P08081 (UniProtKB/Swiss-Prot),   Q5PPP1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000070814   ⟸   ENSRNOT00000083068
RefSeq Acc Id: ENSRNOP00000035138   ⟸   ENSRNOT00000036366
RefSeq Acc Id: ENSRNOP00000019737   ⟸   ENSRNOT00000019737
RefSeq Acc Id: ENSRNOP00000089530   ⟸   ENSRNOT00000101159

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P08081-F1-model_v2 AlphaFold P08081 1-248 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693690
Promoter ID:EPDNEW_R4212
Type:initiation region
Name:Clta_1
Description:clathrin, light chain A
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0559,491,128 - 59,491,188EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:70919 AgrOrtholog
BioCyc Gene G2FUF-41479 BioCyc
Ensembl Genes ENSRNOG00000014635 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000019737 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000035138 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000070814 ENTREZGENE
  ENSRNOP00000070814.1 UniProtKB/TrEMBL
  ENSRNOP00000089530 ENTREZGENE
  ENSRNOP00000089530.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000019737 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000036366 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000083068 ENTREZGENE
  ENSRNOT00000083068.2 UniProtKB/TrEMBL
  ENSRNOT00000101159 ENTREZGENE
  ENSRNOT00000101159.1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7307624 IMAGE-MGC_LOAD
InterPro Clathrin_L-chain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:83800 UniProtKB/Swiss-Prot
MGC_CLONE MGC:105384 IMAGE-MGC_LOAD
NCBI Gene 83800 ENTREZGENE
PANTHER PTHR10639 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Clathrin_lg_ch UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Clta PhenoGen
PROSITE CLATHRIN_LIGHT_CHN_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CLATHRIN_LIGHT_CHN_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JYW3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A7H3 ENTREZGENE, UniProtKB/TrEMBL
  CLCA_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q5PPP1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-08-01 Clta  clathrin, light chain A  Clta  clathrin, light chain (Lca)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-09 Clta  clathrin, light chain (Lca)  Clta  clathrin, light polypeptide (Lca)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-07-09 Clta  clathrin, light polypeptide (Lca)      Symbol and Name updated to reflect Human and Mouse nomenclature 70877 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_domains contains ten heptad elements that may form alpha-helical coiled coils 70686