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Gene: Xpa (XPA, DNA damage recognition and repair factor) Rattus norvegicus
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Symbol: Xpa
Name: XPA, DNA damage recognition and repair factor
Description: Predicted to have damaged DNA binding activity; protein domain specific binding activity; and protein homodimerization activity. Involved in response to auditory stimulus. Localizes to the cytoplasm and nucleus. Predicted to colocalize with the DNA replication factor A complex. Human ortholog(s) of this gene implicated in xeroderma pigmentosum and xeroderma pigmentosum group A. Orthologous to human XPA (XPA, DNA damage recognition and repair factor); PARTICIPATES IN altered nucleotide excision repair pathway; nucleotide excision repair pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: DNA repair protein complementing XP-A cells; LOC298074; xeroderma pigmentosum, complementation group A
Orthologs:
Homo sapiens (human) : XPA (XPA, DNA damage recognition and repair factor)  HGNC  Alliance
Mus musculus (house mouse) : Xpa (xeroderma pigmentosum, complementation group A)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Xpa (XPA, DNA damage recognition and repair factor)
Pan paniscus (bonobo/pygmy chimpanzee) : XPA (XPA, DNA damage recognition and repair factor)
Canis lupus familiaris (dog) : XPA (XPA, DNA damage recognition and repair factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Xpa (XPA, DNA damage recognition and repair factor)
Sus scrofa (pig) : XPA (XPA, DNA damage recognition and repair factor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0561,749,767 - 61,793,641 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl561,749,767 - 61,792,928 (-)Ensembl
Rnor_5.0566,266,229 - 66,310,103 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4562,706,719 - 62,750,771 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1562,726,371 - 62,750,949 (-)NCBI
Celera558,992,396 - 59,036,208 (-)NCBICelera
Cytogenetic Map5q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Xpa
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1308769
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.