Cd72 (Cd72 molecule) - Rat Genome Database

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Gene: Cd72 (Cd72 molecule) Rattus norvegicus
Analyze
Symbol: Cd72
Name: Cd72 molecule
RGD ID: 1309757
Description: Predicted to enable transmembrane signaling receptor activity. Predicted to be integral component of plasma membrane. Orthologous to human CD72 (CD72 molecule); PARTICIPATES IN B cell receptor signaling pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 17beta-estradiol 3-benzoate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: B-cell differentiation antigen CD72; CD72 antigen; LOC313498; MGC108873
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2557,697,361 - 57,704,980 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl557,697,367 - 57,704,725 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx559,676,971 - 59,684,361 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0561,495,784 - 61,503,174 (-)NCBIRnor_SHRSP
Rnor_6.0558,943,021 - 58,950,373 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl558,943,027 - 58,950,373 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0563,468,967 - 63,476,319 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4559,918,085 - 59,925,437 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1559,918,265 - 59,925,616 (-)NCBI
Celera556,279,067 - 56,286,414 (-)NCBICelera
Cytogenetic Map5q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
plasma membrane  (IBA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:1711157  


Genomics

Comparative Map Data
Cd72
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2557,697,361 - 57,704,980 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl557,697,367 - 57,704,725 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx559,676,971 - 59,684,361 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0561,495,784 - 61,503,174 (-)NCBIRnor_SHRSP
Rnor_6.0558,943,021 - 58,950,373 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl558,943,027 - 58,950,373 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0563,468,967 - 63,476,319 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4559,918,085 - 59,925,437 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1559,918,265 - 59,925,616 (-)NCBI
Celera556,279,067 - 56,286,414 (-)NCBICelera
Cytogenetic Map5q22NCBI
CD72
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38935,609,982 - 35,646,857 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl935,609,982 - 35,646,810 (-)EnsemblGRCh38hg38GRCh38
GRCh37935,609,979 - 35,618,410 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36935,599,976 - 35,608,408 (-)NCBINCBI36Build 36hg18NCBI36
Build 34935,599,975 - 35,608,408NCBI
Celera935,543,537 - 35,551,985 (-)NCBICelera
Cytogenetic Map9p13.3NCBI
HuRef935,565,670 - 35,574,101 (-)NCBIHuRef
CHM1_1935,609,802 - 35,618,250 (-)NCBICHM1_1
T2T-CHM13v2.0935,630,646 - 35,639,077 (-)NCBIT2T-CHM13v2.0
Cd72
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39443,447,724 - 43,454,720 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl443,446,462 - 43,454,628 (-)EnsemblGRCm39 Ensembl
GRCm38443,447,724 - 43,455,102 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl443,446,462 - 43,454,628 (-)EnsemblGRCm38mm10GRCm38
MGSCv37443,460,596 - 43,467,498 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36443,468,835 - 43,475,663 (-)NCBIMGSCv36mm8
Celera443,481,359 - 43,488,244 (-)NCBICelera
Cytogenetic Map4A5NCBI
cM Map423.04NCBI
Cd72
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955472663,451 - 670,890 (+)NCBIChiLan1.0ChiLan1.0
CD72
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1936,264,494 - 36,272,952 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl936,264,500 - 36,273,326 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0935,461,685 - 35,470,578 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
CD72
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11152,170,893 - 52,179,035 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1152,170,893 - 52,178,301 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1150,738,628 - 50,746,460 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01153,235,968 - 53,243,815 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1153,235,987 - 53,243,761 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11151,780,623 - 51,788,443 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01151,764,031 - 51,771,844 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01152,466,183 - 52,474,019 (-)NCBIUU_Cfam_GSD_1.0
Cd72
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947167,072,884 - 167,081,610 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365243,620,464 - 3,629,065 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CD72
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1236,345,913 - 236,373,054 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11236,345,894 - 236,355,755 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21264,070,941 - 264,078,597 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap1q21-q28NCBI
CD72
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11244,979,721 - 44,985,821 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603842,085,393 - 42,094,258 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cd72
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248685,191,285 - 5,198,466 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248685,191,123 - 5,198,466 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Position Markers
RH134422  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2557,697,175 - 57,697,569 (+)MAPPERmRatBN7.2
Rnor_6.0558,942,836 - 58,943,229NCBIRnor6.0
Rnor_5.0563,468,782 - 63,469,175UniSTSRnor5.0
RGSC_v3.4559,917,900 - 59,918,293UniSTSRGSC3.4
Celera556,278,882 - 56,279,275UniSTS
RH 3.4 Map5396.21UniSTS
Cytogenetic Map5q22UniSTS
RH140696  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2557,697,590 - 57,697,977 (+)MAPPERmRatBN7.2
Rnor_6.0558,943,251 - 58,943,637NCBIRnor6.0
Rnor_5.0563,469,197 - 63,469,583UniSTSRnor5.0
RGSC_v3.4559,918,315 - 59,918,701UniSTSRGSC3.4
Celera556,279,297 - 56,279,683UniSTS
Cytogenetic Map5q22UniSTS
RH141088  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2557,697,435 - 57,697,616 (+)MAPPERmRatBN7.2
Rnor_6.0558,943,096 - 58,943,276NCBIRnor6.0
Rnor_5.0563,469,042 - 63,469,222UniSTSRnor5.0
RGSC_v3.4559,918,160 - 59,918,340UniSTSRGSC3.4
Celera556,279,142 - 56,279,322UniSTS
Cytogenetic Map5q22UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)5190450412Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51131345958Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)572947086724018Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
8662454Vetf3Vascular elastic tissue fragility QTL 327.4artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)5228222669540447Rat
7394712Emca13Estrogen-induced mammary cancer QTL 13mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)5982326699753708Rat
634305Mamtr1Mammary tumor resistance QTL 10.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)512789751113558310Rat
1600358Mamtr5Mammary tumor resistance QTL 5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)51887394763873947Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)51887394774251464Rat
8552954Pigfal14Plasma insulin-like growth factor 1 level QTL 149blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)52122674466226744Rat
1578767Stresp17Stress response QTL 174.30.01blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)52795544072955440Rat
1578776Stresp18Stress response QTL 182.9thymus mass (VT:0004954)thymus wet weight (CMO:0000855)52795544072955440Rat
6903292Stl28Serum triglyceride level QTL 282.60.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)52851548973515489Rat
6903306Scl35Serum cholesterol QTL 352.60.0073blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)52851548973515489Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)531663789131345958Rat
1598807Glom12Glomerulus QTL 122.7kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)53321566578215665Rat
1298067Scl15Serum cholesterol level QTL 154.80.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53321566578215665Rat
1302786Kidm8Kidney mass QTL 828.15kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)53321566578215665Rat
1576317Eutr2Estrogen induced uterine response QTL 20.01uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)534730116104251008Rat
2316959Gluco59Glucose level QTL 594.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)534944474113558310Rat
1641922Alcrsp8Alcohol response QTL 8alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)53518915368564008Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)535189153141643988Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
1331773Scl26Serum cholesterol level QTL 263.065blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)54372665686724018Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)543726656129132602Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
1300115Hrtrt7Heart rate QTL 72.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)54786906290099692Rat
9589025Epfw7Epididymal fat weight QTL 720.660.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)54946360094463600Rat
7411561Bw134Body weight QTL 134240.001body mass (VT:0001259)body weight gain (CMO:0000420)54946360094463600Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)550328551141643988Rat
2303615Vencon7Ventilatory control QTL 70.001respiration trait (VT:0001943)respiration rate (CMO:0000289)55098389595983895Rat
2303574Gluco42Glucose level QTL 422blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)55349671998496719Rat
61359EaexExperimental allergic encephalomyelitis QTL x3nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)555715622100715622Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555805606132207589Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:49
Count of miRNA genes:47
Interacting mature miRNAs:49
Transcripts:ENSRNOT00000060442
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 11 1
Low 1 12 34 20 8 20 7 8 10 15 14 10 7
Below cutoff 19 19 17 17 1 3 54 16 21 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000060442   ⟹   ENSRNOP00000057186
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl557,697,367 - 57,704,725 (-)Ensembl
Rnor_6.0 Ensembl558,943,027 - 58,950,373 (-)Ensembl
RefSeq Acc Id: NM_001015016   ⟹   NP_001015016
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2557,697,361 - 57,704,713 (-)NCBI
Rnor_6.0558,943,021 - 58,950,373 (-)NCBI
Rnor_5.0563,468,967 - 63,476,319 (-)NCBI
RGSC_v3.4559,918,085 - 59,925,437 (-)RGD
Celera556,279,067 - 56,286,414 (-)RGD
Sequence:
RefSeq Acc Id: XR_005504444
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2557,697,886 - 57,704,970 (-)NCBI
RefSeq Acc Id: XR_005504445
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2557,697,361 - 57,704,974 (-)NCBI
RefSeq Acc Id: XR_005504446
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2557,697,886 - 57,704,980 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001015016 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH91196 (Get FASTA)   NCBI Sequence Viewer  
  EDL98736 (Get FASTA)   NCBI Sequence Viewer  
  EDL98737 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001015016   ⟸   NM_001015016
- UniProtKB: Q5BK59 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000057186   ⟸   ENSRNOT00000060442
Protein Domains
C-type lectin

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5BK59-F1-model_v2 AlphaFold Q5BK59 1-364 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Damaging Variants


Assembly: Rnor_6.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
5 58943628 58943629 C A snv COP/CrCrl (MCW & UW), PVG/Seac (2019), DA/OlaHsd (2019), F344/DuCrl (2019), F344/NCrl (2019), LEW/Crl (2019), SS/JrHsdMcwi (2019), WAG/RijCrl (2020), WKY/NCrl (2019), WN/N (2020), WKY/N (2020), CDR, CDS, ACI/EurMcwi (MCW), GH/OmrMcwi (MCW), SBH/Ygl (MCW), GK/Ox (RGD), MHS/Gib (RGD), SBH/Ygl (RGD), ACI/EurMcwi (2019), ACI/N (2020), BUF/N (2020), F344/N (2020), F344/Stm (2019), GK/FarMcwi (2019), LEXF4/Stm (2020), LH/MavRrrcAek (2020), LL/MavRrrcAek (2020), LN/MavRrrcAek (2020), MWF/Hsd (2019), SS/JrHsdMcwi (MCW)
5 58944980 58944981 G T snv COP/CrCrl (MCW & UW), SS/JrHsdMcwi (MCW), DA/OlaHsd (2019), F344/DuCrl (2019), F344/NCrl (2019), F344/N (2020), LEW/Crl (2019), LEXF4/Stm (2020), LH/MavRrrcAek (2020), MWF/Hsd (2019), SS/JrHsdMcwi (2019), WAG/RijCrl (2020), WKY/NCrl (2019), WN/N (2020), WKY/N (2020), CDR, CDS, ACI/EurMcwi (MCW), GH/OmrMcwi (MCW), SBH/Ygl (MCW), F344/NRrrc (MCW), LN/MavRrrc (RGD), ACI/EurMcwi (2019), F344/Stm (2019), GK/FarMcwi (2019), LL/MavRrrcAek (2020), LN/MavRrrcAek (2020), PVG/Seac (2019)
5 58945657 58945658 G A snv CDS, LH/MavRrrcAek (2020), SBH/Ygl (MCW), SS/JrHsdMcwi (MCW), F344/NRrrc (MCW), WN/N (MCW), F344/NCrl (RGD), GK/Ox (RGD), LEW/Crl (RGD), LN/MavRrrc (RGD), SBH/Ygl (RGD), SS/JrHsdMcwi (RGD), WKY/NCrl (RGD), ACI/EurMcwi (2019), ACI/N (2020), BUF/N (2020), DA/OlaHsd (2019), F344/DuCrl (2019), F344/NCrl (2019), LEW/Crl (2019), LL/MavRrrcAek (2020), LN/MavRrrcAek (2020), PVG/Seac (2019), SS/JrHsdMcwi (2019), WAG/RijCrl (2020), WKY/NCrl (2019), WKY/N (2020), WN/N (2020), MWF/Hsd (2019), CDR, ACI/EurMcwi (MCW), GH/OmrMcwi (MCW), ACI/N (MCW), Buf/N (MCW), WKY/N (MCW), ACI/EurMcwi (RGD), BBDP/Wor (RGD), LEW/NCrlBR (RGD), LH/MavRrrc (RGD), LL/MavRrrc (RGD), MHS/Gib (RGD), MNS/Gib (RGD), SS/Jr (RGD), WAG/Rij (RGD), WKY/NHsd (RGD), F344/N (2020), F344/Stm (2019), GK/FarMcwi (2019), LEXF4/Stm (2020), COP/CrCrl (MCW & UW)


Assembly: Rnor_5.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
5 63469574 63469575 C A snv ZF (KyushuU), KFRS3B/Kyo (KyushuU), ACI/EurMcwi (MCW), COP/CrCrl (MCW & UW), GH/OmrMcwi (MCW), SBH/Ygl (MCW), SS/JrHsdMcwi (MCW), LH/MavRrrc (KNAW), LL/MavRrrc (KNAW), LN/MavRrrc (KNAW), MHS/Gib (KNAW), SS/Jr (KNAW), SS/JrHsdMcwi (KNAW), WAG/Rij (KNAW), ACI/N (KNAW), ACI/EurMcwi (KNAW), BBDP/WorN (KNAW), BUF/N (KNAW), DA/BklArbNsi (KNAW), F344/NRrrc (SOLiD) (KNAW), F344/NCrl (KNAW), F344/NHsd (KNAW), GK/Ox (KNAW), LEW/Crl (KNAW), LEW/NCrl (KNAW), MNS/Gib (KNAW), SBH/Ygl (KNAW), F344/NRrrc (Illumina) (KNAW), WKY/NCrl (KNAW), WKY/NHsd (KNAW), SDLEF7/Barth (UDEL), LE/OrlBarth (UDEL), Crl:SD (UDEL), HTX/Kyo (KyushuU), F344/NSlc (KyushuU), RCS/Kyo (KyushuU), F344/Stm (KyushuU), HWY/Slc (KyushuU), LEC/Tj (KyushuU), F344/Jcl (KyushuU), DOB/Oda (KyushuU), ZFDM (KyushuU)
5 63469602 63469603 C T snv IS/Kyo (KyushuU), IS-Tlk/Kyo (KyushuU)
5 63470883 63470884 G A snv IS/Kyo (KyushuU), IS-Tlk/Kyo (KyushuU)
5 63470926 63470927 G T snv ACI/EurMcwi (MCW), COP/CrCrl (MCW & UW), GH/OmrMcwi (MCW), SBH/Ygl (MCW), SS/JrHsdMcwi (MCW), LE/OrlBarth (UDEL), Crl:SD (UDEL), F344/NSlc (KyushuU), HWY/Slc (KyushuU)
5 63471528 63471529 G T snv IS/Kyo (KyushuU), IS-Tlk/Kyo (KyushuU)
5 63471603 63471604 G A snv GH/OmrMcwi (MCW), SBH/Ygl (MCW), SS/JrHsdMcwi (MCW), WN/N (KNAW), LH/MavRrrc (KNAW), LL/MavRrrc (KNAW), LN/MavRrrc (KNAW), MHS/Gib (KNAW), SS/Jr (KNAW), SS/JrHsdMcwi (KNAW), WAG/Rij (KNAW), ACI/N (KNAW), ACI/EurMcwi (KNAW), BBDP/WorN (KNAW), BUF/N (KNAW), DA/BklArbNsi (KNAW), F344/NRrrc (SOLiD) (KNAW), F344/NCrl (KNAW), ZFDM (KyushuU), GK/Ox (KNAW), LEW/Crl (KNAW), LEW/NCrl (KNAW), MNS/Gib (KNAW), SBH/Ygl (KNAW), F344/NRrrc (Illumina) (KNAW), WKY/N (KNAW), WKY/NCrl (KNAW), WKY/NHsd (KNAW), SDLEF7/Barth (UDEL), LE/OrlBarth (UDEL), Crl:SD (UDEL), F344/DuCrlCrlj (KyushuU), HTX/Kyo (KyushuU), F344/NSlc (KyushuU), RCS/Kyo (KyushuU), F344/Stm (KyushuU), HWY/Slc (KyushuU), LEC/Tj (KyushuU), F344/Jcl (KyushuU), DOB/Oda (KyushuU), KFRS3B/Kyo (KyushuU), COP/CrCrl (MCW & UW), ACI/EurMcwi (MCW), F344/NHsd (KNAW)


Assembly: RGSC_v3.4

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
5 59918692 59918693 C A snv ACI/EurMcwi (MCW), LCR/2Mco (UMich), COP/CrCrl (MCW & UW), GH/OmrMcwi (MCW), ACI/EurMcwi (ICL), BBDP/WorN (ICL), F344/NCrl (ICL), GK/Ox (ICL), LEW/Crl (ICL), LEW/NCrl (ICL), LH/MavRrrc (ICL), LL/MavRrrc (ICL), LN/MavRrrc (ICL), MHS/Gib (ICL), MNS/Gib (ICL), SBH/Ygl (ICL), SS/Jr (ICL), SS/JrHsdMcwi (ICL), WAG/Rij (ICL), WKY/NCrl (ICL), WKY/NHsd (ICL), HCR/1Mco (UMich), LCR/1Mco (UMich), HCR/2Mco (UMich), SS/JrHsdMcwi (MCW)
5 59920044 59920045 G T snv ACI/EurMcwi (MCW), SS/JrHsdMcwi (MCW), F344/NRrrc (KNAW), COP/CrCrl (MCW & UW), GH/OmrMcwi (MCW), HCR/1Mco (UMich), LCR/1Mco (UMich), LCR/2Mco (UMich)
5 59920646 59920647 G T snv LCR/2Mco (UMich), HCR/2Mco (UMich), HCR/1Mco (UMich)
5 59920721 59920722 G A snv ACI/N (KNAW), BUF/N (KNAW), F344/NRrrc (KNAW), WKY/N (KNAW), WN/N (KNAW), COP/CrCrl (MCW & UW), GH/OmrMcwi (MCW), ACI/EurMcwi (ICL), BBDP/WorN (ICL), F344/NCrl (ICL), LCR/2Mco (UMich), LEW/Crl (ICL), LEW/NCrl (ICL), LH/MavRrrc (ICL), LL/MavRrrc (ICL), LN/MavRrrc (ICL), MHS/Gib (ICL), MNS/Gib (ICL), SBH/Ygl (ICL), SS/Jr (ICL), SS/JrHsdMcwi (ICL), WAG/Rij (ICL), WKY/NCrl (ICL), WKY/NHsd (ICL), HCR/1Mco (UMich), LCR/1Mco (UMich), HCR/2Mco (UMich), SS/JrHsdMcwi (MDC), SS/JrHsdMcwi (MCW), ACI/EurMcwi (MCW), GK/Ox (ICL)


Assembly: mRatBN7.2

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
5 57697968 57697969 C A snv WKY/N (2020), WN/N (2020), WAG/RijCrl (2020), SS/JrHsdMcwi (2019), PVG/Seac (2019), MWF/Hsd (2019), LN/MavRrrcAek (2020), LL/MavRrrcAek (2020), LH/MavRrrcAek (2020), LEXF4/Stm (2020), LEW/Crl (2019), GK/FarMcwi (2019), F344/Stm (2019), F344/N (2020), F344/NCrl (2019), F344/DuCrl (2019), DA/OlaHsd (2019), BUF/N (2020), ACI/N (2020), ACI/EurMcwi (2019), WKY/NCrl (2019)
5 57699997 57699998 G A snv WN/N (2020), WKY/N (2020), WKY/NCrl (2019), WAG/RijCrl (2020), SS/JrHsdMcwi (2019), PVG/Seac (2019), MWF/Hsd (2019), LN/MavRrrcAek (2020), LL/MavRrrcAek (2020), LH/MavRrrcAek (2020), LEXF4/Stm (2020), LEW/Crl (2019), GK/FarMcwi (2019), F344/Stm (2019), F344/N (2020), F344/NCrl (2019), F344/DuCrl (2019), DA/OlaHsd (2019), BUF/N (2020), ACI/EurMcwi (2019), ACI/N (2020)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309757 AgrOrtholog
BioCyc Gene G2FUF-41511 BioCyc
Ensembl Genes ENSRNOG00000017485 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000057186 ENTREZGENE
  ENSRNOP00000057186.2 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000060442 ENTREZGENE
  ENSRNOT00000060442.5 UniProtKB/TrEMBL
Gene3D-CATH 3.10.100.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7374499 IMAGE-MGC_LOAD
InterPro C-type_lectin UniProtKB/TrEMBL
  C-type_lectin-like UniProtKB/TrEMBL
  C-type_lectin_fold UniProtKB/TrEMBL
  CD72-like UniProtKB/TrEMBL
KEGG Report rno:313498 UniProtKB/TrEMBL
MGC_CLONE MGC:108873 IMAGE-MGC_LOAD
NCBI Gene 313498 ENTREZGENE
PANTHER PTHR15028 UniProtKB/TrEMBL
Pfam Lectin_C UniProtKB/TrEMBL
PhenoGen Cd72 PhenoGen
Superfamily-SCOP C-type_lectin_fold UniProtKB/TrEMBL
UniProt Q5BK59 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-09-29 Cd72  Cd72 molecule  Cd72  CD72 antigen  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Cd72  CD72 antigen  Cd72_predicted  CD72 antigen (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Cd72_predicted  CD72 antigen (predicted)      Symbol and Name status set to approved 70820 APPROVED