Aldob (aldolase, fructose-bisphosphate B) - Rat Genome Database
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Gene: Aldob (aldolase, fructose-bisphosphate B) Rattus norvegicus
Analyze
Symbol: Aldob
Name: aldolase, fructose-bisphosphate B
RGD ID: 2090
Description: Exhibits fructose-bisphosphate aldolase activity and phosphatidylcholine binding activity. Involved in several processes, including response to copper ion; response to fructose; and response to interleukin-6. Localizes to several cellular components, including endoplasmic reticulum membrane; lysosome; and perinuclear region of cytoplasm. Used to study type 2 diabetes mellitus. Biomarker of liver benign neoplasm; peritonitis; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in hereditary fructose intolerance syndrome and type 2 diabetes mellitus. Orthologous to human ALDOB (aldolase, fructose-bisphosphate B); PARTICIPATES IN glycolysis pathway; forkhead class A signaling pathway; fructose and mannose metabolic pathway; INTERACTS WITH 17beta-estradiol; 2,2,2-tetramine; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Aldo2; aldolase B; Aldolase B fructose-biphosphate; Aldolase B, fructose-biphosphate; aldolase B, fructose-bisphosphate; fructose-bisphosphate aldolase B; LIV10; liver-type aldolase
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2563,889,045 - 63,902,086 (-)NCBI
Rnor_6.0 Ensembl564,805,773 - 64,818,824 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0564,805,772 - 64,818,813 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0569,297,185 - 69,312,980 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4566,283,165 - 66,296,171 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1566,288,278 - 66,301,295 (-)NCBI
Celera563,706,063 - 63,718,940 (+)NCBICelera
RH 3.4 Map5428.2RGD
Cytogenetic Map5q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1-methylphenanthrene  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2,2-tetramine  (EXP)
2,3,7,8-tetrabromodibenzodioxine  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-hydroxypropanoic acid  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
4-hydroxyphenyl retinamide  (ISO)
acetamide  (EXP)
aflatoxin B1  (ISO)
alcohol  (ISO)
ammonium chloride  (EXP)
ampicillin  (EXP)
belinostat  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
bexarotene  (EXP)
bisphenol A  (EXP,ISO)
bosentan  (ISO)
buta-1,3-diene  (ISO)
cadmium dichloride  (EXP,ISO)
captan  (ISO)
clotrimazole  (ISO)
cobalt dichloride  (EXP)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
deoxynivalenol  (ISO)
dibenz[a,h]anthracene  (ISO)
dibenzo[a,l]pyrene  (ISO)
dibutyl phthalate  (EXP)
dichloroacetic acid  (ISO)
diethyl maleate  (EXP)
doxorubicin  (ISO)
endosulfan  (EXP,ISO)
ethanol  (EXP)
flavonoids  (EXP)
fluoranthene  (ISO)
flutamide  (EXP,ISO)
folpet  (ISO)
fructose  (EXP,ISO)
fumonisin B1  (ISO)
furan  (EXP)
genistein  (ISO)
gentamycin  (EXP)
iron(III) citrate  (ISO)
methapyrilene  (EXP)
metronidazole  (EXP)
N-nitrosodiethylamine  (ISO)
N-nitrosomorpholine  (EXP)
neomycin  (EXP)
niclosamide  (ISO)
O-methyleugenol  (ISO)
obeticholic acid  (ISO)
paracetamol  (EXP,ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
picrotoxin  (EXP)
pirinixic acid  (ISO)
potassium dichromate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
rac-lactic acid  (ISO)
rotenone  (EXP,ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP,ISO)
streptozocin  (EXP)
tebuconazole  (ISO)
titanium dioxide  (ISO)
Triptolide  (EXP)
troglitazone  (ISO)
valproic acid  (ISO)
vancomycin  (EXP)
vinclozolin  (EXP)
zearalenone  (ISO)
zinc sulfate  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
1. Brooks CC and Tolan DR, Am J Hum Genet 1993 Apr;52(4):835-40.
2. Chang CK, etal., Circ Shock. 1993 Sep;41(1):35-9.
3. Cheng P, etal., World J Gastroenterol. 2005 Sep 7;11(33):5117-22.
4. Coyle P, etal., Biol Trace Elem Res. 2003 Apr;92(1):41-54.
5. Daimon M, etal., Biochem Biophys Res Commun. 2003 Mar 21;302(4):751-8.
6. Eschbach E, etal., J Cell Biochem. 2005 May 15;95(2):243-55.
7. Esposito G, etal., Hum Mutat. 2004 Dec;24(6):534.
8. Foemmel RS, etal., J Biol Chem. 1975 Mar 10;250(5):1892-7.
9. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
10. GOA data from the GO Consortium
11. Hatzfeld A, etal., Cancer Res. 1978 Jan;38(1):16-22.
12. Huang Y, etal., Arch Biochem Biophys. 1995 Jul 10;320(2):203-9.
13. Ishii Y, etal., Toxicology. 1997 Jan 15;116(1-3):193-9.
14. Ito J, etal., Arch Biochem Biophys. 1998 Feb 15;350(2):291-7.
15. Ito K, etal., Dev Genet. 1995;17(4):312-8.
16. Koo HY, etal., Biochim Biophys Acta. 2008 May;1782(5):341-8. Epub 2008 Feb 29.
17. Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
18. Lenk SE, etal., J Cell Physiol. 1999 Jan;178(1):17-27.
19. Liu H, etal., J Chromatogr B Biomed Sci Appl. 1997 Dec 5;703(1-2):53-62.
20. MGD data from the GO Consortium
21. Millo H and Werman MJ, J Nutr Biochem. 2000 Jul-Aug;11(7-8):374-81.
22. Minami H, etal., Mol Cell Biol. 2006 Dec;26(23):8770-80. Epub 2006 Sep 18.
23. Munnich A, etal., J Clin Invest. 1985 Mar;75(3):1045-52.
24. NCBI rat LocusLink and RefSeq merged data July 26, 2002
25. Ndisang JF, etal., Endocrinology. 2009 May;150(5):2098-108. Epub 2008 Dec 23.
26. OMIM Disease Annotation Pipeline
27. Parimala R and Sachdanandam P, Mol Cell Biochem. 1993 Aug 11;125(1):59-63.
28. Pipeline to import KEGG annotations from KEGG into RGD
29. Pipeline to import Pathway Interaction Database annotations from NCI into RGD
30. Pipeline to import SMPDB annotations from SMPDB into RGD
31. Plant N, etal., Toxicol Appl Pharmacol. 2002 Sep 1;183(2):127-34.
32. Ratnakumari L and Murthy CR, Neurosci Lett. 1993 Oct 14;161(1):37-40.
33. RGD automated data pipeline
34. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
35. RGD automated import pipeline for gene-chemical interactions
36. RGD comprehensive gene curation
37. Rutter WJ, etal., Ann N Y Acad Sci. 1968 Jun 14;151(1):102-17.
38. Saez DE and Slebe JC, J Cell Biochem. 2000 Apr;78(1):62-72.
39. Shi Q and Lou YJ, Pharmacol Res. 2005 Apr;51(4):303-10.
40. Shih DQ, etal., Proc Natl Acad Sci U S A. 2002 Mar 19;99(6):3818-23.
41. Simon MP, etal., J Biol Chem. 1983 Dec 10;258(23):14576-84.
42. Takano Y, etal., Arch Biochem Biophys. 2000 May 1;377(1):58-64.
43. Tsutsumi K, etal., J Biol Chem 1984 Dec 10;259(23):14572-5.
44. Tsutsumi K, etal., J Biol Chem. 1983 May 25;258(10):6537-42.
45. Wang H, etal., J Biol Chem. 2000 Nov 17;275(46):35953-9.
46. Yanez AJ, etal., J Cell Physiol. 2005 Mar;202(3):743-53.
Additional References at PubMed
PMID:604178   PMID:1834654   PMID:2580098   PMID:2649152   PMID:3383242   PMID:6696436   PMID:9244396   PMID:10625657   PMID:12477932   PMID:17576770   PMID:18000879   PMID:21890532  
PMID:23376485   PMID:23533145   PMID:25637246   PMID:26417114   PMID:27923787  


Genomics

Comparative Map Data
Aldob
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2563,889,045 - 63,902,086 (-)NCBI
Rnor_6.0 Ensembl564,805,773 - 64,818,824 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0564,805,772 - 64,818,813 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0569,297,185 - 69,312,980 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4566,283,165 - 66,296,171 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1566,288,278 - 66,301,295 (-)NCBI
Celera563,706,063 - 63,718,940 (+)NCBICelera
RH 3.4 Map5428.2RGD
Cytogenetic Map5q22NCBI
ALDOB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl9101,420,560 - 101,449,664 (-)EnsemblGRCh38hg38GRCh38
GRCh389101,420,560 - 101,435,774 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh379104,182,842 - 104,198,056 (-)NCBIGRCh37GRCh37hg19GRCh37
GRCh379104,182,842 - 104,198,062 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369103,223,479 - 103,237,926 (-)NCBINCBI36hg18NCBI36
Build 349101,263,213 - 101,277,660NCBI
Celera974,696,447 - 74,711,667 (-)NCBI
Cytogenetic Map9q31.1NCBI
HuRef973,782,293 - 73,797,509 (-)NCBIHuRef
CHM1_19104,329,256 - 104,344,476 (-)NCBICHM1_1
Aldob
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39449,535,993 - 49,549,546 (-)NCBIGRCm39mm39
GRCm38449,535,993 - 49,549,546 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl449,535,995 - 49,549,546 (-)EnsemblGRCm38mm10GRCm38
MGSCv37449,548,867 - 49,562,355 (-)NCBIGRCm37mm9NCBIm37
MGSCv36449,557,095 - 49,570,583 (-)NCBImm8
Celera449,564,249 - 49,577,800 (-)NCBICelera
Cytogenetic Map4B1NCBI
cM Map426.57NCBI
Aldob
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541924,377,427 - 24,389,909 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541924,377,427 - 24,389,909 (+)NCBIChiLan1.0ChiLan1.0
ALDOB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.19100,624,151 - 100,645,030 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9100,624,151 - 100,638,597 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0972,630,064 - 72,650,918 (-)NCBIMhudiblu_PPA_v0panPan3
ALDOB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1158,150,967 - 58,176,319 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11158,150,621 - 58,166,266 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Aldob
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365249,584,302 - 9,592,961 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ALDOB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1243,110,585 - 243,141,418 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11243,127,870 - 243,141,504 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21271,728,934 - 271,735,543 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ALDOB
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11237,993,367 - 38,021,693 (+)NCBI
ChlSab1.1 Ensembl1238,007,265 - 38,021,258 (+)Ensembl
Aldob
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247589,868,223 - 9,880,205 (+)NCBI

Position Markers
RH94455  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0564,805,793 - 64,805,966NCBIRnor6.0
Rnor_5.0569,297,206 - 69,297,379UniSTSRnor5.0
RGSC_v3.4566,283,186 - 66,283,359UniSTSRGSC3.4
Celera563,718,746 - 63,718,919UniSTS
RH 3.4 Map5428.2UniSTS
Cytogenetic Map5q22UniSTS
RH129135  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0564,805,802 - 64,806,014NCBIRnor6.0
Rnor_5.0569,297,215 - 69,297,427UniSTSRnor5.0
RGSC_v3.4566,283,195 - 66,283,407UniSTSRGSC3.4
Celera563,718,698 - 63,718,910UniSTS
RH 3.4 Map5428.2UniSTS
Cytogenetic Map5q22UniSTS
RH129202  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0564,805,808 - 64,805,959NCBIRnor6.0
Rnor_5.0569,297,221 - 69,297,372UniSTSRnor5.0
RGSC_v3.4566,283,201 - 66,283,352UniSTSRGSC3.4
Celera563,718,753 - 63,718,904UniSTS
RH 3.4 Map5425.2UniSTS
Cytogenetic Map5q22UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)5189432042Rat
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)5193273395Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51136640934Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)5152509878720537Rat
8662454Vetf3Vascular elastic tissue fragility QTL 327.4artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)5166658771552720Rat
7394712Emca13Estrogen-induced mammary cancer QTL 13mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)59514842103580403Rat
634305Mamtr1Mammary tumor resistance QTL 10.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)512651967117554267Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)51884791376608178Rat
8552954Pigfal14Plasma insulin-like growth factor 1 level QTL 149blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)52190436366904363Rat
1578767Stresp17Stress response QTL 174.30.01blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)52907889974078899Rat
1578776Stresp18Stress response QTL 182.9thymus mass (VT:0004954)thymus wet weight (CMO:0000855)52907889974078899Rat
6903292Stl28Serum triglyceride level QTL 282.60.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)52964166174641661Rat
6903306Scl35Serum cholesterol QTL 352.60.0073blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)52964166174641661Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)531926122136640934Rat
1298067Scl15Serum cholesterol level QTL 154.80.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53440240979402409Rat
1302786Kidm8Kidney mass QTL 828.15kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)53440240979402409Rat
1598807Glom12Glomerulus QTL 122.7kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)53440240979402409Rat
1576317Eutr2Estrogen induced uterine response QTL 20.01uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)535225432108092802Rat
2316959Gluco59Glucose level QTL 594.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)535661945117554267Rat
1641922Alcrsp8Alcohol response QTL 8alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)53578875670742105Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)535788756147487820Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540777918154732375Rat
1331773Scl26Serum cholesterol level QTL 263.065blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)54440427689432042Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)544404276134502294Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)547745646167946134Rat
1300115Hrtrt7Heart rate QTL 72.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)54872203893587756Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)551418671147487820Rat
9589025Epfw7Epididymal fat weight QTL 720.660.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)55180442696804426Rat
7411561Bw134Body weight QTL 134240.001body mass (VT:0001259)body weight gain (CMO:0000420)55180442696804426Rat
2303615Vencon7Ventilatory control QTL 70.001respiration trait (VT:0001943)respiration rate (CMO:0000289)55330956898309568Rat
2303574Gluco42Glucose level QTL 422blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)555903593100903593Rat
61359EaexExperimental allergic encephalomyelitis QTL x3nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)556902367101902367Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)556991667137729065Rat
1358895Bp254Blood pressure QTL 2543.60.0003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)560072951133313852Rat
61426Scl2Serum cholesterol level QTL 27.30.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)561086525149030144Rat
2316954Rf57Renal function QTL 570kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)56108665393273130Rat
2316957Pur21Proteinuria QTL 216.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)561086653117554114Rat
61386Bp49Blood pressure QTL 4916.6cerebrum integrity trait (VT:0010549)brain infarction volume (CMO:0001013)561612600102331727Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)561612600168109659Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:193
Count of miRNA genes:135
Interacting mature miRNAs:146
Transcripts:ENSRNOT00000009111
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 27 27 27 23
Medium 3 16 14 14 8 5 2
Low 14 14 17 8 9 31 4 28 6 8
Below cutoff 19 1 2 31 8 3

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_012496 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC111278 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC081697 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474056 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209505 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209538 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209583 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209594 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209615 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209621 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209639 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209643 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209782 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209819 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210208 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210450 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210453 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210678 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210849 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ211083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ211156 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ211159 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ211293 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218139 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218217 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218348 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218365 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218397 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218402 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218522 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218551 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218592 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218603 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218665 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218876 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218885 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218911 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218999 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219077 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219096 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219116 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219261 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219384 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219435 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219453 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219528 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219555 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219585 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219590 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219593 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219609 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219640 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219646 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219692 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219698 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219703 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000161 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M10149 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  V01223 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X02283 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X02284 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X02285 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X02286 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X02287 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X02288 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X02289 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X02290 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X02291 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000009111   ⟹   ENSRNOP00000009111
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl564,805,773 - 64,818,813 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000086505   ⟹   ENSRNOP00000075134
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl564,805,773 - 64,818,824 (-)Ensembl
RefSeq Acc Id: NM_012496   ⟹   NP_036628
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2563,889,045 - 63,902,086 (-)NCBI
Rnor_6.0564,805,772 - 64,818,813 (-)NCBI
Rnor_5.0569,297,185 - 69,312,980 (-)NCBI
RGSC_v3.4566,283,165 - 66,296,171 (-)RGD
Celera563,706,063 - 63,718,940 (+)RGD
Sequence:
Reference Sequences
RefSeq Acc Id: NP_036628   ⟸   NM_012496
- UniProtKB: Q66HT1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000009111   ⟸   ENSRNOT00000009111
RefSeq Acc Id: ENSRNOP00000075134   ⟸   ENSRNOT00000086505

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693735
Promoter ID:EPDNEW_R4256
Type:multiple initiation site
Name:Aldob_1
Description:aldolase, fructose-bisphosphate B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0564,818,833 - 64,818,893EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2090 AgrOrtholog
Ensembl Genes ENSRNOG00000006807 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000009111 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000075134 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000009111 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000086505 UniProtKB/TrEMBL
Gene3D-CATH 3.20.20.70 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7109764 IMAGE-MGC_LOAD
InterPro Aldolase_I_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Aldolase_TIM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FBA_I UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:24190 UniProtKB/TrEMBL
MGC_CLONE MGC:93076 IMAGE-MGC_LOAD
NCBI Gene 24190 ENTREZGENE
Pfam Glycolytic UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Aldob PhenoGen
PROSITE ALDOLASE_CLASS_I UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt ALDOB_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q66HT1 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary P70706 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-09 Aldob  aldolase, fructose-bisphosphate B  Aldob  aldolase B, fructose-bisphosphate  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-11-18 Aldob  aldolase B, fructose-bisphosphate  Aldob  aldolase B fructose-bisphosphate  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-05-15 Aldob  aldolase B fructose-bisphosphate  Aldob  aldolase B  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-11-06 Aldob  aldolase B    Aldolase B, fructose-biphosphate  Name updated 625702 APPROVED
2002-06-10 Aldob  Aldolase B, fructose-biphosphate      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in liver 632187
gene_product member of the aldolase enzyme family 632188
gene_protein encodes a protein sequence of 364 amino acid residues 632187