1700009N14Rikl (RIKEN cDNA 1700009N14 gene like) - Rat Genome Database

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Gene: 1700009N14Rikl (RIKEN cDNA 1700009N14 gene like) Rattus norvegicus
Analyze
No known orthologs.
Symbol: 1700009N14Rikl (Ensembl: RGD1306195)
Name: RIKEN cDNA 1700009N14 gene like (Ensembl:similar to RAN protein)
RGD ID: 1306195
Description: Predicted to enable GTPase activity. Predicted to be involved in protein import into nucleus and ribosomal subunit export from nucleus. Predicted to be active in cytoplasm and nucleus; PARTICIPATES IN ribosome biogenesis pathway; RNA transport pathway; INTERACTS WITH 6-propyl-2-thiouracil; acrylamide; C60 fullerene.
Type: protein-coding
RefSeq Status: PREDICTED
Previously known as: hypothetical protein LOC313163; LOC313163; RGD1306195; similar to RAN protein; uncharacterized protein LOC313163
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8559,252,092 - 59,253,468 (+)NCBIGRCr8
mRatBN7.2554,456,005 - 54,457,381 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl554,455,893 - 54,457,677 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx556,466,617 - 56,467,993 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0558,285,757 - 58,287,133 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0558,248,453 - 58,249,829 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0554,480,783 - 54,482,159 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl554,480,787 - 54,482,159 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0559,030,552 - 59,031,928 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4556,705,583 - 56,706,959 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1556,705,761 - 56,707,134 (+)NCBI
Celera553,111,157 - 53,112,533 (+)NCBICelera
Cytogenetic Map5q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA)
nucleus  (IBA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:25931508  


Genomics

Variants

.
Variants in 1700009N14Rikl
4 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:153
Count of miRNA genes:125
Interacting mature miRNAs:137
Transcripts:ENSRNOT00000050030
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)5190450412Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51131345958Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)572947086724018Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
8662454Vetf3Vascular elastic tissue fragility QTL 327.4artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)5228222669540447Rat
7394712Emca13Estrogen-induced mammary cancer QTL 13mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)5982326699753708Rat
1641903Alcrsp3Alcohol response QTL 3response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)51268928557689285Rat
634305Mamtr1Mammary tumor resistance QTL 10.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)512789751113558310Rat
1600358Mamtr5Mammary tumor resistance QTL 5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)51887394763873947Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)51887394774251464Rat
8552954Pigfal14Plasma insulin-like growth factor 1 level QTL 149blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)52122674466226744Rat
1578767Stresp17Stress response QTL 174.30.01blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)52795544072955440Rat
1578776Stresp18Stress response QTL 182.9thymus mass (VT:0004954)thymus wet weight (CMO:0000855)52795544072955440Rat
6903292Stl28Serum triglyceride level QTL 282.60.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)52851548973515489Rat
6903306Scl35Serum cholesterol QTL 352.60.0073blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)52851548973515489Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)531663789131345958Rat
1598807Glom12Glomerulus QTL 122.7kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)53321566578215665Rat
1298067Scl15Serum cholesterol level QTL 154.80.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53321566578215665Rat
1302786Kidm8Kidney mass QTL 828.15kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)53321566578215665Rat
1576317Eutr2Estrogen induced uterine response QTL 20.01uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)534730116104251008Rat
2316959Gluco59Glucose level QTL 594.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)534944474113558310Rat
1641922Alcrsp8Alcohol response QTL 8alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)53518915368564008Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)535189153141643988Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
1331773Scl26Serum cholesterol level QTL 263.065blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)54372665686724018Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)543726656129132602Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
1300115Hrtrt7Heart rate QTL 72.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)54786906290099692Rat
9589025Epfw7Epididymal fat weight QTL 720.660.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)54946360094463600Rat
7411561Bw134Body weight QTL 134240.001body mass (VT:0001259)body weight gain (CMO:0000420)54946360094463600Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)550328551141643988Rat
2303615Vencon7Ventilatory control QTL 70.001respiration trait (VT:0001943)respiration rate (CMO:0000289)55098389595983895Rat
2303574Gluco42Glucose level QTL 422blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)55349671998496719Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system appendage
High
Medium 7
Low 2 2 1 2 2
Below cutoff 8 3 5 3 1 3 2 11 4 1

Sequence


RefSeq Acc Id: ENSRNOT00000050030   ⟹   ENSRNOP00000043623
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl554,455,893 - 54,457,677 (+)Ensembl
Rnor_6.0 Ensembl554,480,787 - 54,482,159 (-)Ensembl
RefSeq Acc Id: NM_001014062   ⟹   NP_001014084
RefSeq Status: PREDICTED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8559,252,092 - 59,253,468 (+)NCBI
mRatBN7.2554,456,005 - 54,457,381 (+)NCBI
Rnor_6.0554,480,783 - 54,482,159 (-)NCBI
Rnor_5.0559,030,552 - 59,031,928 (-)NCBI
RGSC_v3.4556,705,583 - 56,706,959 (+)RGD
Celera553,111,157 - 53,112,533 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001014084 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH82086 (Get FASTA)   NCBI Sequence Viewer  
  EDL98625 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000043623
  ENSRNOP00000043623.3
RefSeq Acc Id: NP_001014084   ⟸   NM_001014062
- UniProtKB: Q66H11 (UniProtKB/TrEMBL),   A6IIQ5 (UniProtKB/TrEMBL),   F7ER02 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000043623   ⟸   ENSRNOT00000050030

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q66H11-F1-model_v2 AlphaFold Q66H11 1-216 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693626
Promoter ID:EPDNEW_R4151
Type:initiation region
Name:RGD1306195_1
Description:similar to RAN protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0554,482,240 - 54,482,300EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306195 AgrOrtholog
BioCyc Gene G2FUF-41612 BioCyc
Ensembl Genes ENSRNOG00000031013 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000050030 ENTREZGENE
  ENSRNOT00000050030.4 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7133820 IMAGE-MGC_LOAD
InterPro P-loop_NTPase UniProtKB/TrEMBL
  Ran_GTPase UniProtKB/TrEMBL
  Small_GTP_bd UniProtKB/TrEMBL
  Small_GTPase UniProtKB/TrEMBL
KEGG Report rno:313163 UniProtKB/TrEMBL
MGC_CLONE MGC:95264 IMAGE-MGC_LOAD
NCBI Gene 313163 ENTREZGENE
PANTHER GTP-BINDING NUCLEAR PROTEIN RAN UniProtKB/TrEMBL
  PTHR24071 UniProtKB/TrEMBL
Pfam Ras UniProtKB/TrEMBL
PhenoGen 1700009N14Rikl PhenoGen
PRINTS GTPRANTC4 UniProtKB/TrEMBL
PROSITE RAB UniProtKB/TrEMBL
  RAN UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
RatGTEx ENSRNOG00000031013 RatGTEx
SMART RAB UniProtKB/TrEMBL
  RAN UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  RHO UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A6IIQ5 ENTREZGENE, UniProtKB/TrEMBL
  F7ER02 ENTREZGENE, UniProtKB/TrEMBL
  Q66H11 ENTREZGENE
UniProt Secondary Q66H11 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 1700009N14Rikl  RIKEN cDNA 1700009N14 gene like  RGD1306195  similar to RAN protein  Symbol and Name Changed 1299863 APPROVED
2005-12-06 RGD1306195  similar to RAN protein  RGD1306195_predicted  similar to RAN protein (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1306195_predicted  similar to RAN protein (predicted)  LOC313163_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC313163_predicted  similar to RAN protein (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL