Invs (inversin) - Rat Genome Database

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Gene: Invs (inversin) Rattus norvegicus
Analyze
Symbol: Invs
Name: inversin
RGD ID: 1563359
Description: Predicted to be involved in negative regulation of canonical Wnt signaling pathway and protein localization to ciliary inversin compartment. Predicted to act upstream of or within several processes, including kidney development; left/right pattern formation; and pancreas development. Predicted to be located in ciliary base. Predicted to be active in ciliary inversin compartment. Human ortholog(s) of this gene implicated in hypertension and nephronophthisis 2. Orthologous to human INVS (inversin); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC313228; RGD1563359; similar to Inv protein - mouse
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8567,406,511 - 67,559,355 (+)NCBIGRCr8
mRatBN7.2562,610,916 - 62,763,813 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl562,610,968 - 62,763,350 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx564,585,540 - 64,741,444 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0566,404,842 - 66,560,742 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0566,374,304 - 66,530,206 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0564,031,131 - 64,180,830 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl564,053,946 - 64,178,759 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0568,548,486 - 68,697,014 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4564,962,873 - 65,120,158 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera564,830,211 - 64,984,549 (-)NCBICelera
Cytogenetic Map5q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Multiple renal cyst development but not situs abnormalities in transgenic RNAi mice against Inv::GFP rescue gene. Kamijho Y, etal., PLoS One. 2014 Feb 24;9(2):e89652. doi: 10.1371/journal.pone.0089652. eCollection 2014.
3. Anomalous development of the hepatobiliary system in the Inv mouse. Mazziotti MV, etal., Hepatology. 1999 Aug;30(2):372-8. doi: 10.1002/hep.510300223.
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left-right axis determination. Otto EA, etal., Nat Genet. 2003 Aug;34(4):413-20. doi: 10.1038/ng1217.
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Sustained cell proliferation of renal epithelial cells in mice with inv mutation. Sugiyama N and Yokoyama T, Genes Cells. 2006 Oct;11(10):1213-24. doi: 10.1111/j.1365-2443.2006.01011.x.
9. Mutations of NPHP2 and NPHP3 in infantile nephronophthisis. Tory K, etal., Kidney Int. 2009 Apr;75(8):839-47. doi: 10.1038/ki.2008.662. Epub 2009 Jan 28.
Additional References at PubMed
PMID:9192865   PMID:9771707   PMID:10549278   PMID:18371931   PMID:20169535   PMID:29395339   PMID:35106541  


Genomics

Comparative Map Data
Invs
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8567,406,511 - 67,559,355 (+)NCBIGRCr8
mRatBN7.2562,610,916 - 62,763,813 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl562,610,968 - 62,763,350 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx564,585,540 - 64,741,444 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0566,404,842 - 66,560,742 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0566,374,304 - 66,530,206 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0564,031,131 - 64,180,830 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl564,053,946 - 64,178,759 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0568,548,486 - 68,697,014 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4564,962,873 - 65,120,158 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera564,830,211 - 64,984,549 (-)NCBICelera
Cytogenetic Map5q22NCBI
INVS
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389100,099,243 - 100,302,175 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9100,099,243 - 100,302,175 (+)EnsemblGRCh38hg38GRCh38
GRCh379102,861,525 - 103,064,457 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369101,901,332 - 102,103,247 (+)NCBINCBI36Build 36hg18NCBI36
Celera973,374,912 - 73,576,755 (+)NCBICelera
Cytogenetic Map9q31.1NCBI
HuRef972,460,680 - 72,662,467 (+)NCBIHuRef
CHM1_19103,007,943 - 103,209,867 (+)NCBICHM1_1
T2T-CHM13v2.09112,270,863 - 112,473,811 (+)NCBIT2T-CHM13v2.0
Invs
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39448,279,707 - 48,431,956 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl448,279,760 - 48,431,954 (+)EnsemblGRCm39 Ensembl
GRCm38448,279,707 - 48,431,956 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl448,279,760 - 48,431,954 (+)EnsemblGRCm38mm10GRCm38
MGSCv37448,292,674 - 48,444,825 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36448,300,923 - 48,453,762 (+)NCBIMGSCv36mm8
Celera448,301,442 - 48,455,346 (+)NCBICelera
Cytogenetic Map4B1NCBI
cM Map426.11NCBI
Invs
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541925,444,582 - 25,581,201 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541925,445,404 - 25,584,244 (-)NCBIChiLan1.0ChiLan1.0
INVS
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21139,150,375 - 39,362,210 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1939,155,507 - 39,364,581 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0971,185,345 - 71,395,015 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1999,302,077 - 99,509,731 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl999,329,528 - 99,508,260 (+)Ensemblpanpan1.1panPan2
INVS
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11157,040,005 - 57,196,465 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1157,040,070 - 57,195,281 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1155,486,857 - 55,638,992 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01158,161,098 - 58,317,346 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1158,161,184 - 58,364,961 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11156,668,538 - 56,820,593 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01156,693,389 - 56,845,533 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01157,392,943 - 57,545,213 (+)NCBIUU_Cfam_GSD_1.0
Invs
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947171,923,221 - 172,130,603 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365248,476,574 - 8,611,620 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365248,470,958 - 8,612,835 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
INVS
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1241,897,764 - 242,059,050 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11241,897,685 - 242,058,293 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21270,324,717 - 270,407,975 (+)NCBISscrofa10.2Sscrofa10.2susScr3
INVS
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11239,138,586 - 39,333,758 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1239,139,505 - 39,333,661 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660353,219,006 - 3,418,780 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Invs
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624825702,347 - 866,353 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624825701,335 - 866,598 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Invs
642 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:263
Count of miRNA genes:163
Interacting mature miRNAs:210
Transcripts:ENSRNOT00000011622
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578776Stresp18Stress response QTL 182.9thymus mass (VT:0004954)thymus wet weight (CMO:0000855)52795544072955440Rat
1298067Scl15Serum cholesterol level QTL 154.80.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53321566578215665Rat
1300115Hrtrt7Heart rate QTL 72.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)54786906290099692Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51131345958Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)51887394774251464Rat
634305Mamtr1Mammary tumor resistance QTL 10.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)512789751113558310Rat
61386Bp49Blood pressure QTL 4916.6cerebrum integrity trait (VT:0010549)brain infarction volume (CMO:0001013)56029343498603051Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)543726656129132602Rat
1598807Glom12Glomerulus QTL 122.7kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)53321566578215665Rat
1302786Kidm8Kidney mass QTL 828.15kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)53321566578215665Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)560293434161481680Rat
6903292Stl28Serum triglyceride level QTL 282.60.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)52851548973515489Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
1578767Stresp17Stress response QTL 174.30.01blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)52795544072955440Rat
7411561Bw134Body weight QTL 134240.001body mass (VT:0001259)body weight gain (CMO:0000420)54946360094463600Rat
1641922Alcrsp8Alcohol response QTL 8alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)53518915368564008Rat
2303615Vencon7Ventilatory control QTL 70.001respiration trait (VT:0001943)respiration rate (CMO:0000289)55098389595983895Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)550328551141643988Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)535189153141643988Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
6903306Scl35Serum cholesterol QTL 352.60.0073blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)52851548973515489Rat
1576317Eutr2Estrogen induced uterine response QTL 20.01uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)534730116104251008Rat
7394712Emca13Estrogen-induced mammary cancer QTL 13mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)5982326699753708Rat
1331773Scl26Serum cholesterol level QTL 263.065blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)54372665686724018Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555805606132207589Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)572947086724018Rat
61359EaexExperimental allergic encephalomyelitis QTL x3nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)555715622100715622Rat
8662454Vetf3Vascular elastic tissue fragility QTL 327.4artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)5228222669540447Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)531663789131345958Rat
61426Scl2Serum cholesterol level QTL 27.30.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)559793399143070159Rat
9589025Epfw7Epididymal fat weight QTL 720.660.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)54946360094463600Rat
2303574Gluco42Glucose level QTL 422blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)55349671998496719Rat
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)5190450412Rat
8552954Pigfal14Plasma insulin-like growth factor 1 level QTL 149blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)52122674466226744Rat
2316954Rf57Renal function QTL 570kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)55979352890450144Rat
1358895Bp254Blood pressure QTL 2543.60.0003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)558829236128034027Rat
2316959Gluco59Glucose level QTL 594.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)534944474113558310Rat
1600358Mamtr5Mammary tumor resistance QTL 5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)51887394763873947Rat
2316957Pur21Proteinuria QTL 216.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)559793528113558156Rat

Markers in Region
BB360193  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2562,759,629 - 62,759,739 (+)MAPPERmRatBN7.2
Rnor_6.0564,176,647 - 64,176,756NCBIRnor6.0
Rnor_5.0568,692,831 - 68,692,940UniSTSRnor5.0
RGSC_v3.4565,115,975 - 65,116,084UniSTSRGSC3.4
Celera564,834,285 - 64,834,394UniSTS
Cytogenetic Map5q22UniSTS
AU048338  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2562,734,760 - 62,734,893 (+)MAPPERmRatBN7.2
Rnor_6.0564,151,804 - 64,151,936NCBIRnor6.0
Rnor_5.0568,667,988 - 68,668,120UniSTSRnor5.0
RGSC_v3.4565,091,353 - 65,091,485UniSTSRGSC3.4
Celera564,859,116 - 64,859,248UniSTS
Cytogenetic Map5q22UniSTS
RH131507  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2562,762,498 - 62,762,687 (+)MAPPERmRatBN7.2
Rnor_6.0564,179,516 - 64,179,704NCBIRnor6.0
Rnor_5.0568,695,700 - 68,695,888UniSTSRnor5.0
RGSC_v3.4565,118,844 - 65,119,032UniSTSRGSC3.4
Celera564,831,337 - 64,831,525UniSTS
RH 3.4 Map5413.6UniSTS
Cytogenetic Map5q22UniSTS
AW530466  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2562,763,574 - 62,763,790 (+)MAPPERmRatBN7.2
Rnor_6.0564,180,592 - 64,180,807NCBIRnor6.0
Rnor_5.0568,696,776 - 68,696,991UniSTSRnor5.0
RGSC_v3.4565,119,920 - 65,120,135UniSTSRGSC3.4
Celera564,830,234 - 64,830,449UniSTS
RH 3.4 Map5414.5UniSTS
Cytogenetic Map5q22UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3
Low 21 141 227 147 69 147 36 45 250 115 142 57 24
Below cutoff

Sequence


Ensembl Acc Id: ENSRNOT00000011622   ⟹   ENSRNOP00000011622
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl562,610,968 - 62,763,350 (+)Ensembl
Rnor_6.0 Ensembl564,053,946 - 64,178,759 (+)Ensembl
RefSeq Acc Id: NM_001107932   ⟹   NP_001101402
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8567,406,511 - 67,559,350 (+)NCBI
mRatBN7.2562,610,968 - 62,763,810 (+)NCBI
Rnor_6.0564,031,131 - 64,180,830 (+)NCBI
Rnor_5.0568,548,486 - 68,697,014 (+)NCBI
RGSC_v3.4564,962,873 - 65,120,158 (+)RGD
Celera564,830,211 - 64,984,549 (-)RGD
Sequence:
RefSeq Acc Id: XM_039109855   ⟹   XP_038965783
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8567,406,530 - 67,559,355 (+)NCBI
mRatBN7.2562,610,916 - 62,763,813 (+)NCBI
RefSeq Acc Id: XM_039109856   ⟹   XP_038965784
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8567,406,530 - 67,559,355 (+)NCBI
mRatBN7.2562,610,923 - 62,763,813 (+)NCBI
RefSeq Acc Id: XM_039109857   ⟹   XP_038965785
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8567,406,530 - 67,559,355 (+)NCBI
mRatBN7.2562,610,930 - 62,763,813 (+)NCBI
RefSeq Acc Id: XM_039109859   ⟹   XP_038965787
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8567,406,530 - 67,549,444 (+)NCBI
mRatBN7.2562,610,930 - 62,753,904 (+)NCBI
RefSeq Acc Id: XM_039109860   ⟹   XP_038965788
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8567,406,530 - 67,549,484 (+)NCBI
mRatBN7.2562,610,930 - 62,753,926 (+)NCBI
RefSeq Acc Id: XM_063287624   ⟹   XP_063143694
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8567,406,530 - 67,526,706 (+)NCBI
RefSeq Acc Id: NP_001101402   ⟸   NM_001107932
- UniProtKB: D4A4A8 (UniProtKB/TrEMBL),   A6KJF5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000011622   ⟸   ENSRNOT00000011622
RefSeq Acc Id: XP_038965783   ⟸   XM_039109855
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038965784   ⟸   XM_039109856
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038965785   ⟸   XM_039109857
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038965788   ⟸   XM_039109860
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038965787   ⟸   XM_039109859
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063143694   ⟸   XM_063287624
- Peptide Label: isoform X5

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A4A8-F1-model_v2 AlphaFold D4A4A8 1-1003 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1563359 AgrOrtholog
BioCyc Gene G2FUF-41358 BioCyc
Ensembl Genes ENSRNOG00000008632 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000011622.8 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.20 UniProtKB/TrEMBL
InterPro Ankyrin_rpt UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/TrEMBL
  IQ_motif_EF-hand-BS UniProtKB/TrEMBL
KEGG Report rno:313228 UniProtKB/TrEMBL
NCBI Gene 313228 ENTREZGENE
PANTHER INVERSIN UniProtKB/TrEMBL
  MOLTING PROTEIN MLT-4 UniProtKB/TrEMBL
Pfam Ank UniProtKB/TrEMBL
  Ank_2 UniProtKB/TrEMBL
  Ank_4 UniProtKB/TrEMBL
  PF00612 UniProtKB/TrEMBL
PhenoGen Invs PhenoGen
PROSITE ANK_REP_REGION UniProtKB/TrEMBL
  ANK_REPEAT UniProtKB/TrEMBL
  PS50096 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000008632 RatGTEx
SMART ANK UniProtKB/TrEMBL
  SM00015 UniProtKB/TrEMBL
Superfamily-SCOP ANK UniProtKB/TrEMBL
UniProt A6KJF5 ENTREZGENE, UniProtKB/TrEMBL
  D4A4A8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-07 Invs  inversin  RGD1563359_predicted  similar to Inv protein - mouse (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1563359_predicted  similar to Inv protein - mouse (predicted)  LOC313228  similar to Inv protein - mouse  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC313228  similar to Inv protein - mouse      Symbol and Name status set to provisional 70820 PROVISIONAL