Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Kdm4c (lysine demethylase 4C) Rattus norvegicus
Symbol: Kdm4c
Name: lysine demethylase 4C
Description: Exhibits chromatin binding activity. Involved in positive regulation of gene expression and positive regulation of neuron differentiation. Localizes to nuclear chromatin. Human ortholog(s) of this gene implicated in several diseases, including autistic disorder; esophagus squamous cell carcinoma; head and neck cancer; renal cell carcinoma; and withdrawal disorder. Orthologous to human KDM4C (lysine demethylase 4C); PARTICIPATES IN histone modification pathway; INTERACTS WITH C60 fullerene; diuron; (-)-epigallocatechin 3-gallate (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Jmjd2c; jumonji domain containing 2C; LOC298144; lysine (K)-specific demethylase 4C; lysine-specific demethylase 4C
Homo sapiens (human) : KDM4C (lysine demethylase 4C)  HGNC  Alliance
Mus musculus (house mouse) : Kdm4c (lysine (K)-specific demethylase 4C)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kdm4c (lysine demethylase 4C)
Pan paniscus (bonobo/pygmy chimpanzee) : KDM4C (lysine demethylase 4C)
Canis lupus familiaris (dog) : KDM4C (lysine demethylase 4C)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kdm4c (lysine demethylase 4C)
Sus scrofa (pig) : KDM4C (lysine demethylase 4C)
Chlorocebus sabaeus (African green monkey) : KDM4C (lysine demethylase 4C)
Heterocephalus glaber (naked mole-rat) : Kdm4c (lysine demethylase 4C)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0590,800,139 - 91,012,662 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl590,800,082 - 91,012,659 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0594,858,214 - 95,061,170 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4592,079,908 - 92,288,809 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1592,086,392 - 92,293,919 (+)NCBI
Celera586,814,234 - 87,010,862 (+)NCBICelera
Cytogenetic Map5q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Kdm4c
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1307528
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.