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Gene: Kdm4c (lysine demethylase 4C) Chinchilla lanigera

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Symbol:

Kdm4c

Name:

lysine demethylase 4C

RGD ID:

8723303

Description:

ENCODES a protein that exhibits chromatin binding (ortholog); enzyme binding (ortholog); histone demethylase activity (ortholog); INVOLVED IN androgen receptor signaling pathway (ortholog); blastocyst formation (ortholog); positive regulation of cell population proliferation (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH alopecia areata (ortholog); autistic disorder (ortholog); breast cancer (ortholog); FOUND IN chromatin (ortholog); pericentric heterochromatin (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

lysine (K)-specific demethylase 4C; lysine-specific demethylase 4C

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	KDM4C (lysine demethylase 4C)	NCBI	Ortholog
Mus musculus (house mouse):	Kdm4c (lysine (K)-specific demethylase 4C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Kdm4c (lysine demethylase 4C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	KDM4C (lysine demethylase 4C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	KDM4C (lysine demethylase 4C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Kdm4c (lysine demethylase 4C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	KDM4C (lysine demethylase 4C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	KDM4C (lysine demethylase 4C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Kdm4c (lysine demethylase 4C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955434	10,685,704 - 11,000,644 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955434	10,646,524 - 11,000,589 (+)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

alopecia areata (ISO)

autistic disorder (ISO)

breast cancer (ISO)

Breast Neoplasms (ISO)

chromosome 9p deletion syndrome (ISO)

esophagus squamous cell carcinoma (ISO)

Experimental Melanoma (ISO)

glycine encephalopathy (ISO)

head and neck cancer (ISO)

Maffucci syndrome (ISO)

medulloblastoma (ISO)

melanoma (ISO)

Ollier disease (ISO)

prostate cancer (ISO)

renal cell carcinoma (ISO)

stomach carcinoma (ISO)

T-cell non-Hodgkin lymphoma (ISO)

withdrawal disorder (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

androgen receptor signaling pathway (ISO)

blastocyst formation (ISO)

positive regulation of cell population proliferation (ISO)

positive regulation of gene expression (ISO)

positive regulation of neuron differentiation (ISO)

positive regulation of transcription by RNA polymerase II (ISO)

regulation of gene expression (ISO)

regulation of stem cell differentiation (ISO)

stem cell population maintenance (ISO)

Cellular Component

chromatin (ISO)

pericentric heterochromatin (ISO)

Molecular Function

chromatin binding (ISO)

enzyme binding (ISO)

histone demethylase activity (ISO)

histone H3K36 demethylase activity (ISO)

histone H3K9 demethylase activity (ISO)

histone H3K9me2/H3K9me3 demethylase activity (ISO)

nuclear androgen receptor binding (ISO)

transcription coactivator activity (ISO)

zinc ion binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

histone modification pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

Kdm4c
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955434	10,685,704 - 11,000,644 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955434	10,646,524 - 11,000,589 (+)	NCBI	ChiLan1.0	ChiLan1.0

KDM4C
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	9	6,720,863 - 7,175,648 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	9	6,720,863 - 7,175,648 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	9	6,720,863 - 7,175,648 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	6,747,654 - 7,165,648 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	9	6,748,082 - 7,165,647	NCBI
Celera	9	6,649,815 - 7,106,122 (+)	NCBI		Celera
Cytogenetic Map	9	p24.1	NCBI
HuRef	9	6,675,237 - 7,130,973 (+)	NCBI		HuRef
CHM1_1	9	6,721,531 - 7,175,696 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	9	6,715,554 - 7,172,114 (+)	NCBI		T2T-CHM13v2.0

Kdm4c
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	74,160,734 - 74,324,101 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	74,160,734 - 74,324,097 (+)	Ensembl		GRCm39 Ensembl
GRCm38	4	74,242,497 - 74,405,864 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	74,242,497 - 74,405,860 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	73,888,401 - 74,051,768 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	73,723,179 - 73,877,092 (+)	NCBI		MGSCv36	mm8
Celera	4	72,763,879 - 72,927,310 (+)	NCBI		Celera
Cytogenetic Map	4	C3	NCBI
cM Map	4	36.06	NCBI

Kdm4c
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	93,146,404 - 93,353,040 (+)	NCBI		GRCr8
mRatBN7.2	5	88,100,710 - 88,306,821 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	88,100,733 - 88,306,818 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	90,550,808 - 90,743,411 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	92,379,831 - 92,572,427 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	92,361,586 - 92,554,190 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	90,800,139 - 91,012,662 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	90,800,082 - 91,012,659 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	94,858,214 - 95,061,170 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	92,079,908 - 92,288,809 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	92,086,392 - 92,293,919 (+)	NCBI
Celera	5	86,814,234 - 87,010,862 (+)	NCBI		Celera
Cytogenetic Map	5	q31	NCBI

KDM4C
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	11	117,411,246 - 117,821,826 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	9	117,417,193 - 117,832,340 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	9	6,568,569 - 6,978,741 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	9	6,746,265 - 7,155,378 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	9	6,746,265 - 7,155,298 (+)	Ensembl	panpan1.1		panPan2

KDM4C
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	11	27,662,764 - 28,101,432 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	11	27,693,536 - 28,101,801 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	11	26,475,828 - 26,885,738 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	11	28,552,268 - 28,967,726 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	11	28,552,287 - 28,968,436 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	11	27,275,497 - 27,696,766 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	11	27,094,962 - 27,512,380 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	11	27,763,444 - 28,174,202 (+)	NCBI		UU_Cfam_GSD_1.0

Kdm4c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	142,745,730 - 143,127,317 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936539	1,198,147 - 1,580,082 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936539	1,198,105 - 1,580,078 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

KDM4C
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	215,071,419 - 215,507,800 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	215,071,335 - 215,507,778 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

KDM4C
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	12	72,346,194 - 72,763,040 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	12	72,347,071 - 72,761,666 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	60,686,049 - 60,981,876 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Kdm4c
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624736	11,382,598 - 11,711,536 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624736	11,254,125 - 11,711,498 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005388674	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01032358	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01032359	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01032360	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01032361	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01032362	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01032363	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01032364	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01032365	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01032366	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01032367	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01032368	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01032369	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDJ01371221	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCLAT00000009436 ⟹ ENSCLAP00000009307

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955434	10,685,704 - 11,000,644 (+)	Ensembl

RefSeq Acc Id:

XM_005388674 ⟹ XP_005388731

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955434	10,646,524 - 11,000,589 (+)	NCBI

Sequence:

show sequence

TCTCCATAGGCCGCGCGGCGCGGGAGCCCCGGGACGACGTGAGGCGCGTGGCCTCCAGCAGGTC
CGGCCCCGCAGGAACCCGAGGCTGACCTAGCCACCATGGAGGCGGTGGAGGCAGAGAGTCCCTT
GAACCCCAGCTGTAAGATCATGACCTTCAGACCCTCCATGGAGGAGTTCCGGGAGTTCAACAAA
TACCTCGCATATATGGAATCTAAAGGAGCTCACCGAGCCGGTCTTGCCAAGGTGATCCCTCCTA
AGGAATGGAAGCCAAGGCGGTGCTATGATGACATTGATAATTTGCTTATTCCAGCACCAATCCA
GCAGATGGTCACAGGGCAGTCGGGGCTGTTCACTCAGTACAACATCCAGAAAAAAGCCATGACC
GTGAAGGAGTTCAGGCAGCTGGCTAACAGTGGCAAATACTGTACCCCAAGATATTTGGACTATG
AAGATTTGGAGCGCAAGTACTGGAAGAATTTAACTTTTGTGGCACCCATCTACGGTGCAGATAT
TAATGGGAGCATATATGATGAGGGTGTGGATGAGTGGAACATAGCTCGCCTAAATACAGTCTTG
GATGTGGTGGAAGAGGAGTGTGGTATTTCCATCGAGGGTGTAAATACCCCCTATCTCTATTTTG
GCATGTGGAAGACCACATTCGCATGGCACACCGAGGATATGGACCTCTACAGCATTAATTATCT
CCATTTTGGAGAGCCCAAGTCTTGGTATGCTATACCCCCGGAGCATGGAAAACGACTTGAAAGA
CTAGCTCAAGGTTTTTTCCCAAGTAGCTCCCAGGGGTGTGATGCATTTCTTCGCCACAAGATGA
CACTGATTTCTCCATCAGTATTGAAGAAATACGGGATTCCTTTTGATAAGATCACCCAGGAGGC
TGGAGAATTTATGATCACTTTCCCATATGGCTACCATGCTGGTTTCAATCATGGTTTCAACTGT
GCAGAATCTACAAATTTTGCTACTGTCAGATGGATTGACTATGGAAAAGTTGCTAAATTGTGCA
CTTGCAGGAAAGACATGGTGAAAATTTCAATGGATATCTTTGTGAGGAAATTTCAGCCCGACCG
ATACCACCTTTGGAAACAAGGGAAGGATATATACACCATCGATCACACGAAGCCTACTCCGGAA
TCTACCCCGGAAGTAAAAGCATGGCTGCAAAGGAGAAGGAAAGTAAGAAAAGGATCCAAAAGCT
TCCAAGGATCCAGGTCTCACCCTAAGAGGCCTAAGGCTGAGGATGATGAAGTGTCAGCTGAAGT
TGATGGGGTAGAGGTCCCTCACCCTCACCCTGGCACAGAGGTCCTCAAGGTTAGCAAACAGCCA
GAAAAAGCAGCAAAGCTGGGGAGCACAGAAGCCCCTCCCAAAGAGGCCGCTGCTGGCACAACAC
GGGTGCATCCAAATTTATTGGGTGGCATCACACTCTCAGGAAACAGCTACTTAAGTACATCTGT
TATGGAGGAGATAAAAACTGAAGGTGGGAAAGCCTGTGGCATAACTACACCATCCGTACCTCCT
GAGGCTGATGATTCCATAGCATTACCTAGTGGCCACTTGAAGGTCCAGGAACCAGACCCAGCTA
AGCTTCCATGGCCGAAGTCGCCTGAGTCGTGTTCCTCAATGGCAGAGAGTAATGGCTTGGTTAC
AGAGGAAGAAGAAAGTGATGTGGAGGGCCACAGTAGTGGCCTTGAACCCGGGGAAATCTCAGCA
GTCCTCAGTGAAGAGCGGAATGGCTTCAAAGTCCCCAGTGTAATAGAAGGAGAGACCAAAACGT
CTAAGAGTTGGCGCCATCCACTTACTAAGCCTCCAGCCAGATCCCCAATGACTCTTGTGAAGCA
GCAGGCAACGAGTGATGAAGAACTGCCTGAGGTTCCATCAATAGAAGAGGAAGTGGAAGAAACA
GAGTCTTGGGCAAAGCCTCTCATTCACCTTTGGCAGACAAAGTCTCCTAACTTTGTGGCTGAGC
AGGAATATAATGCAATTGTAGCAAACATGGAGCCACACTGTGCCATTTGCACCCTGCTTATGCC
ATACTACAAGCCAGATAGCAGCAATGAAGAAAATGATTCTAGATGGGAGACAAAATCGGAGGAA
GTGGTTATGTCGGGAGGCAAGACTAAGCCCCTCATTCCAGAGATGTGTTTTATTTATAGCGAGG
AAAACATCGAGTATTCTCCACCCAATGCCTTCCTTGAAGAGGATGGAACAAGTCTTCTGATTTC
CTGTGCAAAGTGCTGTGTTCGGGTTCATGCAAGTTGTTACGGTGTCCCTTCTCATGAGATCTGT
GCTGGATGGCTGTGTGCCCGGTGCAGAAGAAATGCGTGGACAGCAGAATGCTGCCTCTGCAACC
TGAGAGGGGGTGCTCTGAAGCAAACTAAGAACAATAAGTGGGCCCATGTCATGTGCGCTGTTGC
AGTCCCAGAAGTTCGGTTCACTAATGTCCCCGAAAGAACACAAATAGATGTAGGCAGAATACCT
TTACAGAGGTTGAAATTGAAATGCATGTTCTGCAGACATCGCGTTAAGAAGGTCTCTGGAGCCT
GCATCCAGTGCTCCTACGGCCGTTGCCCTGCTTCCTTCCATGTCACGTGTGCCCATGCTGCTGG
GGTGCTGATGGAGCCTGATGATTGGCCTTACGTGGTGAACATCACCTGCTTCCGACACAAGGTC
ATCCCGAATGTGAAGTCCAAGGCTTGTGAGAAGGCCATCTCCGTGGGCCAGACAGTCATCACAA
AGCATCGGAACACCCGCTACTACAGCTGCCGGGTGATGGCTGTGACGTCGCAGACCTTCTATGA
GGTCATGTTTGATGACGGCTCCTTCAGCAGAGACACGTTTCCTGAGGACATTGTGAGTAGAGAC
TGCATGAAGCTGGGCCCTCCTGCTGAGGGAGAAGTCGTCCAAGTCAAGTGGCCTGATGGCAAGC
TGTATGGGGCAAAATATATTGGATCGAATGTTGCCTACATGTACCAGGTTGAGTTTGAAGACGG
ATCCCAGATAGCGATGAAGAGAGAGGACATCTACACCTTAGATGAAGAGTTACCCAAGAGGGTA
AAGGCTCGCTTCTCCACAGCCTCTGACATGCGATTTGAAGACACGTTTTACGGAGCAGACATAA
TCCAAGGGGAGCGGAAGAGGCAAAGAGTGCTCAGCTCCAGGTTTAAGAATGAGTATGTGGATGA
CCCCGTGTACCGCACTTTTCTGAAGAGCTCTTTCCAGAAGAAGTGTCAGAAGAGACAGTAGTCT
ACCTACAGCGCTGCAGGCAACAGAGAGGAGAGGAAGTGCCAGCCTGGGGGCGGTGCCGTGTGCT
TTGCTGGGGCAGGTGGCTGGGTTTTTCCCTGGCAGTGGTAAACCAGGCTGCCAGCATCTGGTCA
CCAAACAAAGCGCTCATGCTAGTAGTTGGATTCTGCAACCTAAAGTTGTCCCCTAGTCTTGTTT
TATTTGTGAACAATTATCTTCTATGATCCCAAAGAATTTTTCTAAGTGAAAGGATATAATAGTG
AATGACCCACTAGCAAAAGCCACTGCCGGAGGGAAGGTAGGTCCCCATGTGCAGCTCAGGCCCC
TCATCAGGAAACACATGGCGTCTTCCCTCCCGGACCTGGCGGGCAGGCGGAGCCTCTTACCCAG
GTGGGAGGGTGATAATTTATATATTTTTCACAGTCAGGGAAGGACTCTCACTTATTTGTTTCAA
ATGGCAGTTTTTATAAAACATTTTTAAAACACAAATGGCATGTATGGTAATGAGATTTACCCGT
GTGCTATCTGTATCCCCATGTACAGTACTTTTGCATTTTTTTATATTCCTATTACTTTTGATTG
TGTCCGATGAGAACTGAGCTGGCCTTTGTGAAATGAAATTTTTGGCTCTTGAGGAAGAATTCTT
AGGAATTCCATGAGAATTTTATATATTTAAAGAGGGAGATCTGGGGCGTTATTTTTAAACACTT
TTTTTCATAATACCTATTCTAAGTAGATATTTATAAAATGTTTCTTTCATTATGTGTTTGTAAA
ATTAGAGTTTAAATAAATATGCTTTGATGCATAGTTTTGAACTAATGTAACATGATTTTCCTTT
TTAAAACACCCTGAAAATGTACTAGTGTTTAAAAATAAAGATTTCCATTTTCTCCTA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005388731	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000009307
	ENSCLAP00000009307.1

RefSeq Acc Id:

XP_005388731 ⟸ XM_005388674

- UniProtKB:

A0A8C2V4Q5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MEAVEAESPLNPSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPRRCYDDI
DNLLIPAPIQQMVTGQSGLFTQYNIQKKAMTVKEFRQLANSGKYCTPRYLDYEDLERKYWKNLT
FVAPIYGADINGSIYDEGVDEWNIARLNTVLDVVEEECGISIEGVNTPYLYFGMWKTTFAWHTE
DMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRHKMTLISPSVLKKYG
IPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWIDYGKVAKLCTCRKDMVKISMD
IFVRKFQPDRYHLWKQGKDIYTIDHTKPTPESTPEVKAWLQRRRKVRKGSKSFQGSRSHPKRPK
AEDDEVSAEVDGVEVPHPHPGTEVLKVSKQPEKAAKLGSTEAPPKEAAAGTTRVHPNLLGGITL
SGNSYLSTSVMEEIKTEGGKACGITTPSVPPEADDSIALPSGHLKVQEPDPAKLPWPKSPESCS
SMAESNGLVTEEEESDVEGHSSGLEPGEISAVLSEERNGFKVPSVIEGETKTSKSWRHPLTKPP
ARSPMTLVKQQATSDEELPEVPSIEEEVEETESWAKPLIHLWQTKSPNFVAEQEYNAIVANMEP
HCAICTLLMPYYKPDSSNEENDSRWETKSEEVVMSGGKTKPLIPEMCFIYSEENIEYSPPNAFL
EEDGTSLLISCAKCCVRVHASCYGVPSHEICAGWLCARCRRNAWTAECCLCNLRGGALKQTKNN
KWAHVMCAVAVPEVRFTNVPERTQIDVGRIPLQRLKLKCMFCRHRVKKVSGACIQCSYGRCPAS
FHVTCAHAAGVLMEPDDWPYVVNITCFRHKVIPNVKSKACEKAISVGQTVITKHRNTRYYSCRV
MAVTSQTFYEVMFDDGSFSRDTFPEDIVSRDCMKLGPPAEGEVVQVKWPDGKLYGAKYIGSNVA
YMYQVEFEDGSQIAMKREDIYTLDEELPKRVKARFSTASDMRFEDTFYGADIIQGERKRQRVLS
SRFKNEYVDDPVYRTFLKSSFQKKCQKRQ

hide sequence

Ensembl Acc Id:

ENSCLAP00000009307 ⟸ ENSCLAT00000009436

Protein Domains

JmjC JmjN PHD-type

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000006468	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000009436	ENTREZGENE
	ENSCLAT00000009436.1	UniProtKB/TrEMBL
Gene3D-CATH	2.30.30.140	UniProtKB/TrEMBL
	3.10.330.70	UniProtKB/TrEMBL
	3.30.40.10	UniProtKB/TrEMBL
	Cupin	UniProtKB/TrEMBL
InterPro	EPHD	UniProtKB/TrEMBL
	JmjC_dom	UniProtKB/TrEMBL
	JmjN	UniProtKB/TrEMBL
	KDM4_Tudor_2	UniProtKB/TrEMBL
	Tudor	UniProtKB/TrEMBL
	Znf_PHD	UniProtKB/TrEMBL
	Znf_PHD-finger	UniProtKB/TrEMBL
	Znf_RING/FYVE/PHD	UniProtKB/TrEMBL
NCBI Gene	Kdm4c	ENTREZGENE
PANTHER	LYSINE-SPECIFIC DEMETHYLASE	UniProtKB/TrEMBL
	LYSINE-SPECIFIC DEMETHYLASE 4C	UniProtKB/TrEMBL
Pfam	JmjC	UniProtKB/TrEMBL
	JmjN	UniProtKB/TrEMBL
	PHD_2	UniProtKB/TrEMBL
	Tudor_2	UniProtKB/TrEMBL
	zf-HC5HC2H_2	UniProtKB/TrEMBL
PROSITE	EPHD	UniProtKB/TrEMBL
	JMJC	UniProtKB/TrEMBL
	JMJN	UniProtKB/TrEMBL
SMART	JmjC	UniProtKB/TrEMBL
	JmjN	UniProtKB/TrEMBL
	PHD	UniProtKB/TrEMBL
	TUDOR	UniProtKB/TrEMBL
Superfamily-SCOP	Clavaminate synthase-like	UniProtKB/TrEMBL
	Tudor/PWWP/MBT	UniProtKB/TrEMBL
UniProt	A0A8C2V4Q5	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-08-03	Kdm4c	lysine demethylase 4C		lysine (K)-specific demethylase 4C	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations