Gene: Gne (glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase) Rattus norvegicus
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Symbol: Gne
Name: glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
Description: ENCODES a protein that exhibits N-acylmannosamine kinase activity; UDP-N-acetylglucosamine 2-epimerase activity; INVOLVED IN carbohydrate phosphorylation (inferred); N-acetylglucosamine biosynthetic process (inferred); N-acetylneuraminate biosynthetic process (inferred); PARTICIPATES IN amino sugar metabolic pathway; french type sialuria pathway; sialic acid storage disease pathway; ASSOCIATED WITH anauxetic dysplasia 1 (ortholog); autosomal recessive distal spinal muscular atrophy 2 (ortholog); inclusion body myositis (ortholog); FOUND IN cytosol; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol
AGR Description: Exhibits N-acylmannosamine kinase activity and UDP-N-acetylglucosamine 2-epimerase activity; predicted to be involved in N-acetylneuraminate biosynthetic process; localizes to the cytosol; orthologous to human GNE (glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase).
Merged Description: Exhibits N-acylmannosamine kinase activity and UDP-N-acetylglucosamine 2-epimerase activity; predicted to be involved in N-acetylneuraminate biosynthetic process; localizes to the cytosol; orthologous to human GNE (glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase); PARTICIPATES IN amino sugar metabolic pathway; french type sialuria pathway; sialic acid storage disease pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase; glucosamine; Uae1; UDP-GlcNAc-2-epimerase/ManAc kinase; UDP-N-acetylglucosamine-2-epimerase/N-acetylmannosamine kinase
Orthologs:
Homo sapiens (human) : GNE (glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase)  HGNC  Alliance
Mus musculus (house mouse) : Gne (glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gne (glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : GNE (glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase)
Canis lupus familiaris (dog) : GNE (glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gne (glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase)
Sus scrofa (pig) : GNE (glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0559,511,738 - 59,553,421 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0564,034,863 - 64,075,144 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4560,506,171 - 60,536,403 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1560,506,350 - 60,536,582 (-)NCBI
Celera556,845,530 - 56,875,714 (-)NCBICelera
Cytogenetic Map5q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
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Nomenclature History
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More on Gne
Alliance Gene
NCBI Gene
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JBrowse: rn5 rn6
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RGD Object Information
RGD ID: 69239
Created: 2001-11-14
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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