Hsdl2 (hydroxysteroid dehydrogenase like 2) - Rat Genome Database

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Gene: Hsdl2 (hydroxysteroid dehydrogenase like 2) Rattus norvegicus
Analyze
Symbol: Hsdl2
Name: hydroxysteroid dehydrogenase like 2
RGD ID: 1305387
Description: Predicted to enable oxidoreductase activity. Predicted to be located in peroxisome. Predicted to be active in mitochondrion. Orthologous to human HSDL2 (hydroxysteroid dehydrogenase like 2); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: hydroxysteroid dehydrogenase-like protein 2; LOC313200; MGC114452; RGD1305387; similar to RIKEN cDNA 2610207I16
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: LOC100502570  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8579,238,881 - 79,274,051 (+)NCBIGRCr8
mRatBN7.2574,443,933 - 74,479,104 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl574,443,872 - 74,479,839 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx576,348,773 - 76,383,918 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0578,170,407 - 78,205,548 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0578,142,573 - 78,177,716 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0576,812,881 - 76,848,853 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl576,812,931 - 76,848,101 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0580,949,471 - 80,982,924 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4577,680,173 - 77,716,789 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1577,685,285 - 77,721,902 (+)NCBI
Celera573,270,683 - 73,297,340 (+)NCBICelera
Cytogenetic Map5q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
22-Hydroxycholesterol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amiodarone  (EXP)
aristolochic acid A  (ISO)
azathioprine  (ISO)
benzbromarone  (EXP)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
buspirone  (EXP)
cadmium atom  (ISO)
cisplatin  (EXP,ISO)
clofibrate  (EXP,ISO)
cobalt dichloride  (EXP)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
decabromodiphenyl ether  (EXP)
decanoyl-CoA  (ISO)
dichloroacetic acid  (ISO)
dicrotophos  (ISO)
doxorubicin  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
fenofibrate  (EXP)
finasteride  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
glafenine  (EXP)
GW 501516  (ISO)
hexadecanoic acid  (ISO)
indole-3-methanol  (EXP)
ivermectin  (ISO)
L-ethionine  (EXP)
lauroyl-CoA  (ISO)
leflunomide  (EXP)
methyl methanesulfonate  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
Muraglitazar  (EXP)
N-nitrosodiethylamine  (EXP)
NADP zwitterion  (ISO)
NADP(+)  (ISO)
nefazodone  (EXP)
nimesulide  (EXP)
oleic acid  (ISO)
omeprazole  (EXP)
oxybenzone  (EXP)
paracetamol  (EXP,ISO)
pentachlorophenol  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP,ISO)
permethrin  (ISO)
pirinixic acid  (EXP,ISO)
potassium chromate  (ISO)
pravastatin  (EXP,ISO)
resveratrol  (ISO)
rotenone  (EXP)
tacrolimus hydrate  (ISO)
Tesaglitazar  (EXP)
testosterone  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
tolcapone  (EXP)
trichloroethene  (ISO)
trichostatin A  (ISO)
troglitazone  (EXP)
valdecoxib  (EXP)
valproic acid  (ISO)
vinclozolin  (EXP)
zaragozic acid A  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
mitochondrion  (IBA,IEA,ISO)
peroxisome  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:12477932   PMID:14651853   PMID:18614015   PMID:19703561   PMID:19946888   PMID:26316108  


Genomics

Comparative Map Data
Hsdl2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8579,238,881 - 79,274,051 (+)NCBIGRCr8
mRatBN7.2574,443,933 - 74,479,104 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl574,443,872 - 74,479,839 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx576,348,773 - 76,383,918 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0578,170,407 - 78,205,548 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0578,142,573 - 78,177,716 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0576,812,881 - 76,848,853 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl576,812,931 - 76,848,101 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0580,949,471 - 80,982,924 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4577,680,173 - 77,716,789 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1577,685,285 - 77,721,902 (+)NCBI
Celera573,270,683 - 73,297,340 (+)NCBICelera
Cytogenetic Map5q24NCBI
HSDL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389112,380,108 - 112,472,405 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9112,380,080 - 112,472,405 (+)EnsemblGRCh38hg38GRCh38
GRCh379115,142,388 - 115,234,685 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369114,182,172 - 114,274,505 (+)NCBINCBI36Build 36hg18NCBI36
Build 349112,221,905 - 112,314,239NCBI
Celera985,641,314 - 85,733,588 (+)NCBICelera
Cytogenetic Map9q32NCBI
HuRef984,740,909 - 84,833,213 (+)NCBIHuRef
CHM1_19115,288,820 - 115,381,275 (+)NCBICHM1_1
T2T-CHM13v2.09124,551,300 - 124,643,585 (+)NCBIT2T-CHM13v2.0
Hsdl2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39459,581,515 - 59,618,694 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl459,581,563 - 59,618,689 (+)EnsemblGRCm39 Ensembl
GRCm38459,581,517 - 59,618,694 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl459,581,563 - 59,618,689 (+)EnsemblGRCm38mm10GRCm38
MGSCv37459,594,435 - 59,631,566 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36459,675,744 - 59,712,121 (+)NCBIMGSCv36mm8
Celera459,498,692 - 59,535,802 (+)NCBICelera
Cytogenetic Map4B3NCBI
cM Map432.69NCBI
Hsdl2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541914,899,010 - 14,974,213 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541914,899,141 - 14,974,449 (-)NCBIChiLan1.0ChiLan1.0
HSDL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21126,959,583 - 27,053,770 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1926,958,840 - 27,056,130 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0983,509,669 - 83,606,283 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19111,665,915 - 111,758,934 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9111,665,915 - 111,758,934 (+)Ensemblpanpan1.1panPan2
HSDL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11166,883,021 - 66,944,844 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1166,883,022 - 66,944,837 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1165,291,492 - 65,353,214 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01168,012,425 - 68,074,256 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1168,011,963 - 68,078,339 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11166,528,893 - 66,590,567 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01166,552,345 - 66,614,072 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01167,296,644 - 67,358,400 (+)NCBIUU_Cfam_GSD_1.0
Hsdl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947182,215,203 - 182,274,397 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936559990,357 - 1,051,346 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936559992,152 - 1,051,312 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HSDL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1253,124,471 - 253,194,951 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11253,124,358 - 253,191,309 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21283,908,621 - 283,976,160 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HSDL2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11227,051,287 - 27,132,884 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1226,999,960 - 27,131,914 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603515,664,940 - 15,748,041 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hsdl2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476022,504,213 - 22,580,548 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476022,503,455 - 22,580,473 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Hsdl2
92 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:49
Count of miRNA genes:40
Interacting mature miRNAs:48
Transcripts:ENSRNOT00000059458
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)5190450412Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51131345958Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)572947086724018Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
7394712Emca13Estrogen-induced mammary cancer QTL 13mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)5982326699753708Rat
634305Mamtr1Mammary tumor resistance QTL 10.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)512789751113558310Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)531663789131345958Rat
1598807Glom12Glomerulus QTL 122.7kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)53321566578215665Rat
1298067Scl15Serum cholesterol level QTL 154.80.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53321566578215665Rat
1302786Kidm8Kidney mass QTL 828.15kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)53321566578215665Rat
1576317Eutr2Estrogen induced uterine response QTL 20.01uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)534730116104251008Rat
2316959Gluco59Glucose level QTL 594.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)534944474113558310Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)535189153141643988Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
1331773Scl26Serum cholesterol level QTL 263.065blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)54372665686724018Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)543726656129132602Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
1300115Hrtrt7Heart rate QTL 72.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)54786906290099692Rat
9589025Epfw7Epididymal fat weight QTL 720.660.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)54946360094463600Rat
7411561Bw134Body weight QTL 134240.001body mass (VT:0001259)body weight gain (CMO:0000420)54946360094463600Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)550328551141643988Rat
2303615Vencon7Ventilatory control QTL 70.001respiration trait (VT:0001943)respiration rate (CMO:0000289)55098389595983895Rat
2303574Gluco42Glucose level QTL 422blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)55349671998496719Rat
61359EaexExperimental allergic encephalomyelitis QTL x3nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)555715622100715622Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555805606132207589Rat
1358895Bp254Blood pressure QTL 2543.60.0003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)558829236128034027Rat
61426Scl2Serum cholesterol level QTL 27.30.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)559793399143070159Rat
2316954Rf57Renal function QTL 570kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)55979352890450144Rat
2316957Pur21Proteinuria QTL 216.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)559793528113558156Rat
61386Bp49Blood pressure QTL 4916.6cerebrum integrity trait (VT:0010549)brain infarction volume (CMO:0001013)56029343498603051Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)560293434161481680Rat
2290005Mcs24Mammary carcinoma susceptibility QTL 24mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)564719390109719390Rat
2306971Anxrr21Anxiety related response QTL 219.47fear/anxiety-related behavior trait (VT:1000241)number of entries into a discrete space in an experimental apparatus (CMO:0000960)566174080124160948Rat
2312671Scl64Serum cholesterol level QTL 640.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)568984307104251008Rat
61380Edpm5Estrogen-dependent pituitary mass QTL 54.50.92pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)568984307104251008Rat
1357396Bw44Body weight QTL 444.19body mass (VT:0001259)body weight (CMO:0000012)568984307104251008Rat
1357402Bw46Body weight QTL 464.47body mass (VT:0001259)body mass index (BMI) (CMO:0000105)568984307104251008Rat
2302381Bw84Body weight QTL 844.47body mass (VT:0001259)body mass index (BMI) (CMO:0000105)568984307104251008Rat
1354598Srn6Serum renin concentration QTL 63.8blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)569540295151018848Rat

Markers in Region
RH129399  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2574,444,271 - 74,444,422 (+)MAPPERmRatBN7.2
Rnor_6.0576,813,270 - 76,813,420NCBIRnor6.0
Rnor_5.0580,949,810 - 80,949,960UniSTSRnor5.0
RGSC_v3.4577,680,512 - 77,680,662UniSTSRGSC3.4
RH 3.4 Map5530.2UniSTS
Cytogenetic Map5q24UniSTS
RH129574  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2574,478,771 - 74,478,959 (+)MAPPERmRatBN7.2
Rnor_6.0576,847,773 - 76,847,960NCBIRnor6.0
Rnor_5.0580,982,592 - 80,982,779UniSTSRnor5.0
Celera573,297,008 - 73,297,195UniSTS
Cytogenetic Map5q24UniSTS
RH136809  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2574,443,093 - 74,443,341 (+)MAPPERmRatBN7.2
Rnor_6.0576,812,090 - 76,812,337NCBIRnor6.0
Rnor_5.0580,948,630 - 80,948,877UniSTSRnor5.0
RGSC_v3.4577,679,332 - 77,679,579UniSTSRGSC3.4
RH 3.4 Map5529.4UniSTS
Cytogenetic Map5q24UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 72 35 41 11 8
Low 2
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000059458   ⟹   ENSRNOP00000056213
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl574,451,397 - 74,479,098 (+)Ensembl
Rnor_6.0 Ensembl576,812,931 - 76,848,101 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000105089   ⟹   ENSRNOP00000091225
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl574,443,872 - 74,479,111 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000119367   ⟹   ENSRNOP00000082012
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl574,443,972 - 74,479,839 (+)Ensembl
RefSeq Acc Id: NM_001025697   ⟹   NP_001020868
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8579,238,881 - 79,274,051 (+)NCBI
mRatBN7.2574,443,933 - 74,479,104 (+)NCBI
Rnor_6.0576,812,931 - 76,848,105 (+)NCBI
Rnor_5.0580,949,471 - 80,982,924 (+)NCBI
RGSC_v3.4577,680,173 - 77,716,789 (+)RGD
Celera573,270,683 - 73,297,340 (+)RGD
Sequence:
RefSeq Acc Id: NP_001020868   ⟸   NM_001025697
- UniProtKB: Q4V8F9 (UniProtKB/Swiss-Prot),   A0A8L2QRI7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000056213   ⟸   ENSRNOT00000059458
RefSeq Acc Id: ENSRNOP00000091225   ⟸   ENSRNOT00000105089
RefSeq Acc Id: ENSRNOP00000082012   ⟸   ENSRNOT00000119367
Protein Domains
SCP2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q4V8F9-F1-model_v2 AlphaFold Q4V8F9 1-524 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693772
Promoter ID:EPDNEW_R4296
Type:initiation region
Name:Hsdl2_1
Description:hydroxysteroid dehydrogenase like 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0576,812,992 - 76,813,052EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305387 AgrOrtholog
BioCyc Gene G2FUF-41146 BioCyc
Ensembl Genes ENSRNOG00000016692 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00055018841 UniProtKB/Swiss-Prot
  ENSRNOG00060010224 UniProtKB/Swiss-Prot
  ENSRNOG00065015078 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000059458.5 UniProtKB/TrEMBL
  ENSRNOT00000105089 ENTREZGENE
  ENSRNOT00000105089.1 UniProtKB/TrEMBL
  ENSRNOT00000119367.1 UniProtKB/TrEMBL
  ENSRNOT00055032162 UniProtKB/Swiss-Prot
  ENSRNOT00060017317 UniProtKB/Swiss-Prot
  ENSRNOT00065025045 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.1050.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NAD(P)-binding Rossmann-like Domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7454038 IMAGE-MGC_LOAD
InterPro NAD(P)-bd_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SCP2_sterol-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SCP2_sterol-bd_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SDR_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:313200 UniProtKB/Swiss-Prot
MGC_CLONE MGC:114452 IMAGE-MGC_LOAD
NCBI Gene 313200 ENTREZGENE
PANTHER HYDROXYSTEROID DEHYDROGENASE-LIKE PROTEIN 2 UniProtKB/Swiss-Prot
  HYDROXYSTEROID DEHYDROGENASE-LIKE PROTEIN 2 UniProtKB/Swiss-Prot
  HYDROXYSTEROID DEHYDROGENASE-LIKE PROTEIN 2 UniProtKB/TrEMBL
  HYDROXYSTEROID DEHYDROGENASE-LIKE PROTEIN 2 UniProtKB/TrEMBL
Pfam adh_short UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SCP2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Hsdl2 PhenoGen
PRINTS GDHRDH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000016692 RatGTEx
  ENSRNOG00055018841 RatGTEx
  ENSRNOG00060010224 RatGTEx
  ENSRNOG00065015078 RatGTEx
Superfamily-SCOP SSF51735 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF55718 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZUC6_RAT UniProtKB/TrEMBL
  A0A8I6AF67_RAT UniProtKB/TrEMBL
  A0A8L2QRI7 ENTREZGENE, UniProtKB/TrEMBL
  HSDL2_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-06 Hsdl2  hydroxysteroid dehydrogenase like 2  RGD1305387  similar to RIKEN cDNA 2610207I16  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 RGD1305387  similar to RIKEN cDNA 2610207I16  RGD1305387_predicted  similar to RIKEN cDNA 2610207I16 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1305387_predicted  similar to RIKEN cDNA 2610207I16 (predicted)  LOC313200_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC313200_predicted  similar to RIKEN cDNA 2610207I16 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL