Obp3 (alpha-2u globulin PGCL4) - Rat Genome Database

Name: Obp3
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Obp3 (alpha-2u globulin PGCL4) Rattus norvegicus

Analyze

Symbol:

Obp3

Name:

alpha-2u globulin PGCL4

RGD ID:

708508

Description:

Enables odorant binding activity. Predicted to be located in extracellular region; INTERACTS WITH 1,4-dichlorobenzene; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

alpha2 urinary globulin; LOC100911890; LOC259247; major urinary protein-like; MGC108576; odorant-binding protein 3

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	5	74,842,316 - 74,845,858 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	74,842,316 - 74,845,757 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	76,742,298 - 76,745,735 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	78,563,933 - 78,567,370 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	78,536,108 - 78,539,545 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	77,313,357 - 77,316,875 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	5	81,534,432 - 81,537,931 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	78,088,876 - 78,092,317 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	78,093,991 - 78,097,430 (-)	NCBI
Celera	5	73,651,817 - 73,655,258 (-)	NCBI		Celera
Cytogenetic Map	5	q24	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Chemical and Drug Induced Liver Injury (EXP)

Experimental Liver Cirrhosis (EXP)

liver cirrhosis (EXP)

liver disease (EXP)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,4-dichlorobenzene (EXP)

1-naphthyl isothiocyanate (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2-nitrofluorene (EXP)

3H-1,2-dithiole-3-thione (EXP)

4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one (EXP)

5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole (EXP)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

aflatoxin B1 (EXP)

amiodarone (EXP)

amitrole (EXP)

ammonium chloride (EXP)

benzbromarone (EXP)

buspirone (EXP)

clofibrate (EXP)

clofibric acid (EXP)

decabromodiphenyl ether (EXP)

dexamethasone (EXP)

diethylstilbestrol (EXP)

erythromycin estolate (EXP)

ethanol (EXP)

ether (EXP)

furan (EXP)

indole-3-methanol (EXP)

isoflurane (EXP)

L-ethionine (EXP)

lead diacetate (EXP)

limonene (EXP)

methapyrilene (EXP)

methimazole (EXP)

methotrexate (EXP)

Methyl isobutyl ketone (EXP)

N-nitrosodiethylamine (EXP)

N-nitrosodimethylamine (EXP)

nimesulide (EXP)

omeprazole (EXP)

paclitaxel (EXP)

paracetamol (EXP)

pentobarbital (EXP)

piperonyl butoxide (EXP)

pirinixic acid (EXP)

rotenone (EXP)

sodium dichromate (EXP)

sulfadimethoxine (EXP)

tetrachloromethane (EXP)

thioacetamide (EXP)

trichloroethene (EXP)

triphenyl phosphate (EXP)

trovafloxacin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

extracellular region (IEA)

Molecular Function

odorant binding (IDA)

pheromone binding (IEA)

small molecule binding (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Length heterogeneity in rat salivary gland alpha 2 mu globulin mRNAs: multiple splice-acceptors and polyadenylation sites.	Gao F, etal., Nucleic Acids Res 1989 Jun 26;17(12):4629-36.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Tissue-specific control of alpha 2u globulin gene expression: constitutive synthesis in the submaxillary gland.	Laperche Y, etal., Cell 1983 Feb;32(2):453-60.
4.	Identification of a third rat odorant-binding protein (OBP3).	Lobel D, etal., Chem Senses 2001 Jul;26(6):673-80.
5.	Odorants of different chemical classes interact with distinct odorant binding protein subtypes.	Lobel D, etal., Chem Senses 2002 Jan;27(1):39-44.
6.	GOA pipeline	RGD automated data pipeline
7.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
8.	Molecular evidence of complex tissue- and sex-specific mRNA expression of the rat alpha(2u)-globulin multigene family.	Saito K, etal., Biochem Biophys Res Commun 2000 Jun 7;272(2):337-44.

Additional References at PubMed

PMID:2439333	PMID:2558970	PMID:12477932	PMID:21536621	PMID:23131471	PMID:24665925	PMID:25109974	PMID:25853804

Genomics

Variants

Variants in Obp3
34 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	46
Count of miRNA genes:	44
Interacting mature miRNAs:	45
Transcripts:	ENSRNOT00000071395
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1331756	Rf34	Renal function QTL 34	4.16275		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	5	1	90450412	Rat
70212	Niddm25	Non-insulin dependent diabetes mellitus QTL 25	3.54		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	5	1	131345958	Rat
1331771	Rf35	Renal function QTL 35	4.36965		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	5	729470	86724018	Rat
1576314	Eutr1	Estrogen induced uterine response QTL 1			uterus integrity trait (VT:0010575)	pyometritis severity score (CMO:0002009)	5	2138965	166875058	Rat
7394712	Emca13	Estrogen-induced mammary cancer QTL 13			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	9823266	99753708	Rat
634305	Mamtr1	Mammary tumor resistance QTL 1		0.0001	mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	12789751	113558310	Rat
2290448	Scl54	Serum cholesterol level QTL 54	2.93		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	31663789	131345958	Rat
1598807	Glom12	Glomerulus QTL 12	2.7		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	5	33215665	78215665	Rat
1298067	Scl15	Serum cholesterol level QTL 15	4.8	0.001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	33215665	78215665	Rat
1302786	Kidm8	Kidney mass QTL 8	28.15		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	5	33215665	78215665	Rat
1576317	Eutr2	Estrogen induced uterine response QTL 2		0.01	uterus integrity trait (VT:0010575)	pyometritis severity score (CMO:0002009)	5	34730116	104251008	Rat
2316959	Gluco59	Glucose level QTL 59	4.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	5	34944474	113558310	Rat
1641912	Alcrsp18	Alcohol response QTL 18			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	5	35189153	141643988	Rat
1549845	Scl44	Serum cholesterol level QTL 44	6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	40128307	148607290	Rat
1331773	Scl26	Serum cholesterol level QTL 26	3.065		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	43726656	86724018	Rat
1331801	Rf33	Renal function QTL 33	4.149		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	5	43726656	129132602	Rat
1578766	Tcas11	Tongue tumor susceptibility QTL 11	4.12		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	5	46711509	161317411	Rat
1300115	Hrtrt7	Heart rate QTL 7	2.76		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	5	47869062	90099692	Rat
9589025	Epfw7	Epididymal fat weight QTL 7	20.66	0.001	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	5	49463600	94463600	Rat
7411561	Bw134	Body weight QTL 134	24	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	49463600	94463600	Rat
1576312	Emca8	Estrogen-induced mammary cancer QTL 8	4.1		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	50328551	141643988	Rat
2303615	Vencon7	Ventilatory control QTL 7		0.001	respiration trait (VT:0001943)	respiration rate (CMO:0000289)	5	50983895	95983895	Rat
2303574	Gluco42	Glucose level QTL 42	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	5	53496719	98496719	Rat
61359	Eaex	Experimental allergic encephalomyelitis QTL x	3		nervous system integrity trait (VT:0010566)	post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)	5	55715622	100715622	Rat
70189	Mcs5	Mammary carcinoma susceptibility QTL 5	10.51		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	55805606	132207589	Rat
1358895	Bp254	Blood pressure QTL 254	3.6	0.0003	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	5	58829236	128034027	Rat
61426	Scl2	Serum cholesterol level QTL 2	7.3	0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	59793399	143070159	Rat
2316954	Rf57	Renal function QTL 57	0		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	5	59793528	90450144	Rat
2316957	Pur21	Proteinuria QTL 21	6.2		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	5	59793528	113558156	Rat
61386	Bp49	Blood pressure QTL 49	16.6		cerebrum integrity trait (VT:0010549)	brain infarction volume (CMO:0001013)	5	60293434	98603051	Rat
61393	Bp7	Blood pressure QTL 7	4.5	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	60293434	161481680	Rat
2290005	Mcs24	Mammary carcinoma susceptibility QTL 24			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	64719390	109719390	Rat
2306971	Anxrr21	Anxiety related response QTL 21	9.47		fear/anxiety-related behavior trait (VT:1000241)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	5	66174080	124160948	Rat
2312671	Scl64	Serum cholesterol level QTL 64		0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	68984307	104251008	Rat
61380	Edpm5	Estrogen-dependent pituitary mass QTL 5	4.5	0.92	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	5	68984307	104251008	Rat
1357396	Bw44	Body weight QTL 44	4.19		body mass (VT:0001259)	body weight (CMO:0000012)	5	68984307	104251008	Rat
1357402	Bw46	Body weight QTL 46	4.47		body mass (VT:0001259)	body mass index (BMI) (CMO:0000105)	5	68984307	104251008	Rat
2302381	Bw84	Body weight QTL 84	4.47		body mass (VT:0001259)	body mass index (BMI) (CMO:0000105)	5	68984307	104251008	Rat
1354598	Srn6	Serum renin concentration QTL 6	3.8		blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	5	69540295	151018848	Rat

Markers in Region

RH130736

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	75,142,184 - 75,142,391 (+)	MAPPER	mRatBN7.2
mRatBN7.2	5	75,394,151 - 75,394,358 (+)	MAPPER	mRatBN7.2
mRatBN7.2	5	74,842,350 - 74,842,557 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	77,549,951 - 77,550,157	NCBI	Rnor6.0
Rnor_6.0	5	77,744,252 - 77,744,458	NCBI	Rnor6.0
Rnor_5.0	5	81,870,493 - 81,870,699	UniSTS	Rnor5.0
Rnor_5.0	5	81,680,425 - 81,680,631	UniSTS	Rnor5.0
RH 3.4 Map	5	556.7	UniSTS
Cytogenetic Map	5	q24	UniSTS

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001033958	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001033959	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_147215	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017593740	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039109323	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039109324	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039109325	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039109326	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005504371	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005504372	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB039825	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC086942	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474039	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	J00738	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000161	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X05613	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X14552	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000043056 ⟹ ENSRNOP00000048604

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	74,842,316 - 74,845,757 (-)	Ensembl

RefSeq Acc Id:

NM_001033958 ⟹ NP_001029130

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	5	74,842,316 - 74,845,757 (-)	NCBI
RGSC_v3.4	5	78,088,876 - 78,092,317 (-)	RGD
Celera	5	73,651,817 - 73,655,258 (-)	NCBI

Sequence:

show sequence

TGGGCACCATCAGCAGAGAGATTGTCCCGACAGAGAGGCAATTCTATTCCCTACCAACATGAAG
CTGTTGCTGCTGCTGCTGTGTCTGGGCCTGACCCTGGTCTGTGGCCATGCAGAAGAAGCTAGTT
TCGAGAGAGGGAACCTCGATGTGGACAAGCTCAATGGGGATTGGTTTTCTATTGTCGTGGCCTC
TGATAAAAGAGAAAAGATAGAAGAGAACGGCAGCATGAGAGTTTTTGTGCAGCATATCGATGTC
TTGGAGAATTCCTTAGGCTTCACGTTCCGTATTAAGGAAAATGGAGTGTGCACAGAATTTTCTT
TGGTTGCCGACAAAACAGCAAAGGATGGCGAATATTTTGTTGAGTATGACGGAGAGAATACATT
TACTATACTTAAGACAGACTATGACAATTATGTCATGTTTCATCTCGTTAATGTCAACAACGGG
GAAACCTTCCAGCTGATGGAGCTCTATGGCAGAACAAAGGATCTGAGTTCAGACATCAAGGAAA
AGTTTGCAAAACTATGTGTGGCACATGGAATCACTAGGGACAATATCATTGACCTAACCAAGAC
TGATCGCTGTCTCCAGGCCTGAGGTTGAAGAAAGGCCTGAGCCTCCAGAGTGCCTCTCTGTCCA
GAAGTCAATCCAAGAAGTGCTTAATGGGTTCCTTTATTCTTTCTTCCTGGATTACTCCATGCTG
AGTGGAGACTTCTCACCAGGACTCCAGCATTACCATTTCCTGTCCATGGAGCATCCTGAGACAA
ATTCTGCGATCTGATTTCCATCCTGTCTCACAGAAAAGTGCAATCCCGGTCTCTCCAGCATCTT
CCCTAGTTACCCAGGACAACACATCGAGAATTAAAAGCTTTCTTAAATTTCTCTTTGCCCCACC
CATGATCATTCCGCACAAATTTCTTGCTCTTGCAGTGCAATAAATGATTACCCTTGCACTTAAA

hide sequence

RefSeq Acc Id:

NM_001033959 ⟹ NP_001029131

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	5	74,842,316 - 74,845,757 (-)	NCBI
RGSC_v3.4	5	78,088,876 - 78,092,317 (-)	RGD
Celera	5	73,651,817 - 73,655,258 (-)	NCBI

Sequence:

show sequence

TGGGCACCATCAGCAGAGAGATTGTCCCGACAGAGAGGCAATTCTATTCCCTACCAACATGAAG
CTGTTGCTGCTGCTGCTGTGTCTGGGCCTGACCCTGGTCTGTGGCCATGCAGAAGAAGCTAGTT
TCGAGAGAGGGAACCTCGATGTGGACAAGCTCAATGGGGATTGGTTTTCTATTGTCGTGGCCTC
TGATAAAAGAGAAAAGATAGAAGAGAACGGCAGCATGAGAGTTTTTGTGCAGCATATCGATGTC
TTGGAGAATTCCTTAGGCTTCACGTTCCGTATTAAGGAAAATGGAGTGTGCACAGAATTTTCTT
TGGTTGCCGACAAAACAGCAAAGGATGGCGAATATTTTGTTGAGTATGACGGAGAGAATACATT
TACTATACTTAAGACAGACTATGACAATTATGTCATGTTTCATCTCGTTAATGTCAACAACGGG
GAAACCTTCCAGCTGATGGAGCTCTATGGCAGAACAAAGGATCTGAGTTCAGACATCAAGGAAA
AGTTTGCAAAACTATGTGTGGCACATGGAATCACTAGGGACAATATCATTGACCTAACCAAGAC
TGATCGCTGTCTCCAGGCCTGAGGTTGAAGAAAGGCCTGAGCCTCCAGACTTCTCACCAGGACT
CCAGCATTACCATTTCCTGTCCATGGAGCATCCTGAGACAAATTCTGCGATCTGATTTCCATCC
TGTCTCACAGAAAAGTGCAATCCCGGTCTCTCCAGCATCTTCCCTAGTTACCCAGGACAACACA
TCGAGAATTAAAAGCTTTCTTAAATTTCTCTTTGCCCCACCCATGATCATTCCGCACAAATTTC
TTGCTCTTGCAGTGCAATAAATGATTACCCTTGCACTTAAA

hide sequence

RefSeq Acc Id:

NM_147215 ⟹ NP_671748

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	5	74,842,316 - 74,845,757 (-)	NCBI
RGSC_v3.4	5	78,088,876 - 78,092,317 (-)	RGD
Celera	5	73,651,817 - 73,655,258 (-)	NCBI

Sequence:

show sequence

TGGGCACCATCAGCAGAGAGATTGTCCCGACAGAGAGGCAATTCTATTCCCTACCAACATGAAG
CTGTTGCTGCTGCTGCTGTGTCTGGGCCTGACCCTGGTCTGTGGCCATGCAGAAGAAGCTAGTT
TCGAGAGAGGGAACCTCGATGTGGACAAGCTCAATGGGGATTGGTTTTCTATTGTCGTGGCCTC
TGATAAAAGAGAAAAGATAGAAGAGAACGGCAGCATGAGAGTTTTTGTGCAGCATATCGATGTC
TTGGAGAATTCCTTAGGCTTCACGTTCCGTATTAAGGAAAATGGAGTGTGCACAGAATTTTCTT
TGGTTGCCGACAAAACAGCAAAGGATGGCGAATATTTTGTTGAGTATGACGGAGAGAATACATT
TACTATACTTAAGACAGACTATGACAATTATGTCATGTTTCATCTCGTTAATGTCAACAACGGG
GAAACCTTCCAGCTGATGGAGCTCTATGGCAGAACAAAGGATCTGAGTTCAGACATCAAGGAAA
AGTTTGCAAAACTATGTGTGGCACATGGAATCACTAGGGACAATATCATTGACCTAACCAAGAC
TGATCGCTGTCTCCAGGCCTGAGGTTGAAGAAAGGCCTGAGCCTCCAGATTGCAGGGCAAGATC
TATTTCTTCATCCTTTGTTCTATACAATAGAGTGCCTCTCTGTCCAGAAGTCAATCCAAGAAGT
GCTTAATGGGTTCCTTTATTCTTTCTTCCTGGATTACTCCATGCTGAGTGGAGACTTCTCACCA
GGACTCCAGCATTACCATTTCCTGTCCATGGAGCATCCTGAGACAAATTCTGCGATCTGATTTC
CATCCTGTCTCACAGAAAAGTGCAATCCCGGTCTCTCCAGCATCTTCCCTAGTTACCCAGGACA
ACACATCGAGAATTAAAAGCTTTCTTAAATTTCTCTTTGCCCCACCCATGATCATTCCGCACAA
ATTTCTTGCTCTTGCAGTGCAATAAATGATTACCCTTGCACTTAAA

hide sequence

RefSeq Acc Id:

XM_039109323 ⟹ XP_038965251

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	5	74,842,316 - 74,845,857 (-)	NCBI

RefSeq Acc Id:

XM_039109324 ⟹ XP_038965252

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	5	74,842,316 - 74,845,858 (-)	NCBI

RefSeq Acc Id:

XM_039109325 ⟹ XP_038965253

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	5	74,842,316 - 74,845,858 (-)	NCBI

RefSeq Acc Id:

XM_039109326 ⟹ XP_038965254

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	5	74,842,316 - 74,845,858 (-)	NCBI

RefSeq Acc Id:

XR_005504371

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	5	74,842,316 - 74,845,858 (-)	NCBI

RefSeq Acc Id:

XR_005504372

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	5	74,842,316 - 74,845,858 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001029130	(Get FASTA)	NCBI Sequence Viewer
	NP_001029131	(Get FASTA)	NCBI Sequence Viewer
	NP_671748	(Get FASTA)	NCBI Sequence Viewer
	XP_038965251	(Get FASTA)	NCBI Sequence Viewer
	XP_038965252	(Get FASTA)	NCBI Sequence Viewer
	XP_038965253	(Get FASTA)	NCBI Sequence Viewer
	XP_038965254	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA88508	(Get FASTA)	NCBI Sequence Viewer
	AAH86942	(Get FASTA)	NCBI Sequence Viewer
	BAA96482	(Get FASTA)	NCBI Sequence Viewer
	CAA32690	(Get FASTA)	NCBI Sequence Viewer
	CAE82009	(Get FASTA)	NCBI Sequence Viewer
	EDL91625	(Get FASTA)	NCBI Sequence Viewer
	EDL91626	(Get FASTA)	NCBI Sequence Viewer
	EDL91627	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_671748 ⟸ NM_147215
- Peptide Label:	precursor
- UniProtKB:	Q78E14 (UniProtKB/TrEMBL), F8WFF8 (UniProtKB/TrEMBL), A0A9K3Y8C3 (UniProtKB/TrEMBL), Q63022 (UniProtKB/TrEMBL), Q63213 (UniProtKB/TrEMBL)
- Sequence:	show sequence MKLLLLLLCLGLTLVCGHAEEASFERGNLDVDKLNGDWFSIVVASDKREKIEENGSMRVFVQHI DVLENSLGFTFRIKENGVCTEFSLVADKTAKDGEYFVEYDGENTFTILKTDYDNYVMFHLVNVN NGETFQLMELYGRTKDLSSDIKEKFAKLCVAHGITRDNIIDLTKTDRCLQA hide sequence

RefSeq Acc Id:	NP_001029130 ⟸ NM_001033958
- Peptide Label:	precursor
- UniProtKB:	Q78E14 (UniProtKB/TrEMBL), F8WFF8 (UniProtKB/TrEMBL), A0A9K3Y8C3 (UniProtKB/TrEMBL), Q63022 (UniProtKB/TrEMBL), Q63213 (UniProtKB/TrEMBL)
- Sequence:	show sequence MKLLLLLLCLGLTLVCGHAEEASFERGNLDVDKLNGDWFSIVVASDKREKIEENGSMRVFVQHI DVLENSLGFTFRIKENGVCTEFSLVADKTAKDGEYFVEYDGENTFTILKTDYDNYVMFHLVNVN NGETFQLMELYGRTKDLSSDIKEKFAKLCVAHGITRDNIIDLTKTDRCLQA hide sequence

RefSeq Acc Id:	NP_001029131 ⟸ NM_001033959
- Peptide Label:	precursor
- UniProtKB:	Q78E14 (UniProtKB/TrEMBL), F8WFF8 (UniProtKB/TrEMBL), A0A9K3Y8C3 (UniProtKB/TrEMBL), Q63022 (UniProtKB/TrEMBL), Q63213 (UniProtKB/TrEMBL)
- Sequence:	show sequence MKLLLLLLCLGLTLVCGHAEEASFERGNLDVDKLNGDWFSIVVASDKREKIEENGSMRVFVQHI DVLENSLGFTFRIKENGVCTEFSLVADKTAKDGEYFVEYDGENTFTILKTDYDNYVMFHLVNVN NGETFQLMELYGRTKDLSSDIKEKFAKLCVAHGITRDNIIDLTKTDRCLQA hide sequence

RefSeq Acc Id:	XP_038965254 ⟸ XM_039109326
- Peptide Label:	isoform X2
- UniProtKB:	F8WFF8 (UniProtKB/TrEMBL), Q78E14 (UniProtKB/TrEMBL), A0A9K3Y8C3 (UniProtKB/TrEMBL), Q63022 (UniProtKB/TrEMBL), Q63213 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038965253 ⟸ XM_039109325
- Peptide Label:	isoform X2
- UniProtKB:	F8WFF8 (UniProtKB/TrEMBL), Q78E14 (UniProtKB/TrEMBL), A0A9K3Y8C3 (UniProtKB/TrEMBL), Q63022 (UniProtKB/TrEMBL), Q63213 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038965252 ⟸ XM_039109324
- Peptide Label:	isoform X2
- UniProtKB:	F8WFF8 (UniProtKB/TrEMBL), Q78E14 (UniProtKB/TrEMBL), A0A9K3Y8C3 (UniProtKB/TrEMBL), Q63022 (UniProtKB/TrEMBL), Q63213 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038965251 ⟸ XM_039109323
- Peptide Label:	isoform X1
- UniProtKB:	Q63022 (UniProtKB/TrEMBL), Q63213 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSRNOP00000048604 ⟸ ENSRNOT00000043056

Protein Domains

Lipocalin/cytosolic fatty-acid binding

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-F8WFF8-F1-model_v2	AlphaFold	F8WFF8	1-181	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
BioCyc Gene	G2FUF-41131	BioCyc
Ensembl Genes	ENSRNOG00000065108	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000048604	ENTREZGENE
	ENSRNOP00000048604.6	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000043056	ENTREZGENE
	ENSRNOT00000043056.7	UniProtKB/TrEMBL
Gene3D-CATH	2.40.128.20	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7369206	IMAGE-MGC_LOAD
InterPro	Calycin	UniProtKB/TrEMBL
	Lipocalin	UniProtKB/TrEMBL
	Lipocalin_CS	UniProtKB/TrEMBL
	Lipocln_cytosolic_FA-bd_dom	UniProtKB/TrEMBL
	Maj_urinary	UniProtKB/TrEMBL
KEGG Report	rno:259247	UniProtKB/TrEMBL
MGC_CLONE	MGC:108576	IMAGE-MGC_LOAD
NCBI Gene	259247	ENTREZGENE
PANTHER	MAJOR URINARY PROTEIN 1-RELATED	UniProtKB/TrEMBL
	PTHR11430	UniProtKB/TrEMBL
Pfam	Lipocalin	UniProtKB/TrEMBL
PhenoGen	Obp3	PhenoGen
PRINTS	LIPOCALIN	UniProtKB/TrEMBL
	MAJORURINARY	UniProtKB/TrEMBL
PROSITE	LIPOCALIN	UniProtKB/TrEMBL
Superfamily-SCOP	Calycin	UniProtKB/TrEMBL
UniProt	A0A9K3Y8C3	ENTREZGENE, UniProtKB/TrEMBL
	F8WFF8	ENTREZGENE
	Q63022	ENTREZGENE
	Q63213	ENTREZGENE, UniProtKB/TrEMBL
	Q78E14	ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary	F8WFF8	UniProtKB/TrEMBL
	Q63022	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-07-29	Obp3	alpha-2u globulin PGCL4	LOC100911890	major urinary protein-like	Data Merged	737654	PROVISIONAL
2012-07-05	LOC100911890	major urinary protein-like			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD