Napepld (N-acyl phosphatidylethanolamine phospholipase D) - Rat Genome Database

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Gene: Napepld (N-acyl phosphatidylethanolamine phospholipase D) Rattus norvegicus
Analyze
Symbol: Napepld
Name: N-acyl phosphatidylethanolamine phospholipase D
RGD ID: 735197
Description: Exhibits phospholipase activity. Involved in several processes, including aging; negative regulation of eating behavior; and response to isolation stress. Localizes to membrane-bounded organelle. Biomarker of osteoarthritis. Orthologous to human NAPEPLD (N-acyl phosphatidylethanolamine phospholipase D); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D; NAPE-hydrolyzing phospholipase D; NAPE-PLD
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2413,360,532 - 13,398,815 (+)NCBI
Rnor_6.0 Ensembl49,966,891 - 10,002,247 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.049,965,323 - 10,004,650 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.049,966,483 - 10,005,809 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.448,821,727 - 8,845,709 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.148,821,726 - 8,845,709 (+)NCBI
Celera48,954,741 - 8,975,084 (+)NCBICelera
Cytogenetic Map4q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References

Additional References at PubMed
PMID:15249196   PMID:15992380   PMID:16818490   PMID:19056867   PMID:25684574   PMID:25757720  


Genomics

Comparative Map Data
Napepld
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2413,360,532 - 13,398,815 (+)NCBI
Rnor_6.0 Ensembl49,966,891 - 10,002,247 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.049,965,323 - 10,004,650 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.049,966,483 - 10,005,809 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.448,821,727 - 8,845,709 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.148,821,726 - 8,845,709 (+)NCBI
Celera48,954,741 - 8,975,084 (+)NCBICelera
Cytogenetic Map4q11NCBI
NAPEPLD
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl7103,099,776 - 103,149,560 (-)EnsemblGRCh38hg38GRCh38
GRCh387103,099,776 - 103,150,001 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh377102,740,223 - 102,790,448 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367102,527,459 - 102,576,741 (-)NCBINCBI36hg18NCBI36
Celera797,547,949 - 97,597,471 (-)NCBI
Cytogenetic Map7q22.1NCBI
HuRef797,103,121 - 97,152,369 (-)NCBIHuRef
CHM1_17102,673,431 - 102,722,953 (-)NCBICHM1_1
CRA_TCAGchr7v27102,100,389 - 102,149,935 (-)NCBI
Napepld
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39521,867,899 - 21,906,620 (-)NCBIGRCm39mm39
GRCm39 Ensembl521,867,899 - 21,906,394 (-)Ensembl
GRCm38521,662,901 - 21,701,622 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl521,662,901 - 21,701,396 (-)EnsemblGRCm38mm10GRCm38
MGSCv37521,168,721 - 21,207,163 (-)NCBIGRCm37mm9NCBIm37
MGSCv36521,174,727 - 21,213,169 (-)NCBImm8
Celera518,631,024 - 18,671,982 (-)NCBICelera
Cytogenetic Map5A3NCBI
Napepld
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554108,220,400 - 8,247,486 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554108,217,684 - 8,233,302 (-)NCBIChiLan1.0ChiLan1.0
NAPEPLD
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.17107,923,952 - 107,973,269 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7107,923,960 - 107,973,269 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0795,074,084 - 95,123,936 (-)NCBIMhudiblu_PPA_v0panPan3
NAPEPLD
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11816,945,096 - 16,990,752 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1816,945,253 - 17,009,607 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1816,599,554 - 16,650,199 (+)NCBI
ROS_Cfam_1.01817,253,389 - 17,307,355 (+)NCBI
UMICH_Zoey_3.11817,011,890 - 17,062,566 (+)NCBI
UNSW_CanFamBas_1.01816,950,687 - 17,001,305 (+)NCBI
UU_Cfam_GSD_1.01817,219,297 - 17,269,945 (+)NCBI
Napepld
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511859,135,563 - 59,172,683 (+)NCBI
SpeTri2.0NW_00493647920,259,260 - 20,293,116 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NAPEPLD
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9103,210,748 - 103,262,454 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19103,210,655 - 103,309,018 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29113,620,593 - 113,632,997 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NAPEPLD
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12172,174,451 - 72,224,932 (-)NCBI
ChlSab1.1 Ensembl2172,178,041 - 72,224,559 (-)Ensembl
Vero_WHO_p1.0NW_02366604231,777,904 - 31,826,799 (+)NCBI
Napepld
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473926,117,665 - 26,152,322 (+)NCBI


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
619616Bp79Blood pressure QTL 790.0292arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4304323179575658Rat
631209Bw2Body weight QTL24.2retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)4646769343414792Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)43043231145254791Rat
2302371Stl22Serum triglyceride level QTL 225.15blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4304401755791834Rat
631261Tcas3Tongue tumor susceptibility QTL 36.88tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)4734240492484039Rat
724557Plsm1Polydactyly-luxate syndrome (PLS) morphotypes QTL 10.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)4125545519Rat
631642Stl2Serum triglyceride level QTL 23.3blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4304780755324857Rat
738021Hcar13Hepatocarcinoma resistance QTL 134.3liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)4131554484Rat
1300141Bp178Blood pressure QTL 178arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)4657293937703537Rat
1641905Colcr1Colorectal carcinoma resistance QTL 14.30.0003intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)4126654881Rat
634323Hc2Hypercalciuria QTL 22.15urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)4142118977Rat
1357341Gluco5Glucose level QTL 56.4adipocyte free fatty acid secretion trait (VT:0010465)absolute change in adipocyte free fatty acid secretion per unit volume (CMO:0001446)4129778604Rat
1357343Gluco4Glucose level QTL 40.00002adipocyte glucose uptake trait (VT:0004185)adipocyte maximal glucose uptake to basal glucose uptake ratio (CMO:0000874)4129778604Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)47850904182171018Rat
1358201Gluco12Glucose level QTL121.6adipocyte glucose uptake trait (VT:0004185)adipocyte maximal glucose uptake (CMO:0000870)4304411426753655Rat
1358203Stl19Serum triglyceride level QTL 192.80.002blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4304401764915903Rat
61333Gluco16Glucose level QTL 164.30.00001adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)4126803291Rat
61351Bp33Blood pressure QTL 330.0018arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4125545519Rat
61408Scl23Serum cholesterol level QTL 230.0005blood HDL phospholipid amount (VT:0010504)serum high density lipoprotein phospholipid level (CMO:0001567)4125545519Rat
6478724Anxrr35Anxiety related response QTL 350.00449defecation behavior trait (VT:0010462)defecation measurement (CMO:0000997)4805218953052189Rat
6478766Anxrr47Anxiety related response QTL 470.09637locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)4805218953052189Rat
6478769Anxrr48Anxiety related response QTL 480.02514locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4805218953052189Rat
8694374Bw155Body weight QTL 1553.390.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)4805218953052189Rat
9589097Slep11Serum leptin concentration QTL 115.090.001blood leptin amount (VT:0005667)plasma leptin level (CMO:0000781)4128352196Rat
9590304Scort17Serum corticosterone level QTL 174.960.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)4805218953052189Rat
8552903Pigfal2Plasma insulin-like growth factor 1 level QTL 27.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)4128352196Rat
9589046Scfw2Subcutaneous fat weight QTL 25.540.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)4128352196Rat
8552906Pigfal3Plasma insulin-like growth factor 1 level QTL 3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)4805218953052189Rat
9590100Sffal4Serum free fatty acids level QTL 47.360.05blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)4128352196Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:83
Count of miRNA genes:75
Interacting mature miRNAs:79
Transcripts:ENSRNOT00000015322
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 30 23 18 15
Low 3 13 57 41 19 41 8 11 51 17 26 11 8
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_199381 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006235908 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006235910 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006235911 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008762639 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592516 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592517 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107241 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107242 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107243 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107244 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107245 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB112351 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC130776 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HH770744 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000141 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000015322   ⟹   ENSRNOP00000015322
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl49,981,958 - 10,002,247 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000086609   ⟹   ENSRNOP00000073608
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl49,966,891 - 9,997,267 (+)Ensembl
RefSeq Acc Id: NM_199381   ⟹   NP_955413
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2413,376,115 - 13,396,405 (+)NCBI
Rnor_6.049,981,958 - 10,002,247 (+)NCBI
Rnor_5.049,966,483 - 10,005,809 (+)NCBI
RGSC_v3.448,821,727 - 8,845,709 (+)RGD
Celera48,954,741 - 8,975,084 (+)RGD
Sequence:
RefSeq Acc Id: XM_006235908   ⟹   XP_006235970
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2413,360,532 - 13,398,815 (+)NCBI
Rnor_6.049,965,323 - 10,004,650 (+)NCBI
Rnor_5.049,966,483 - 10,005,809 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006235910   ⟹   XP_006235972
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2413,361,015 - 13,398,815 (+)NCBI
Rnor_6.049,966,859 - 10,004,650 (+)NCBI
Rnor_5.049,966,483 - 10,005,809 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006235911   ⟹   XP_006235973
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2413,361,015 - 13,398,815 (+)NCBI
Rnor_6.049,966,859 - 10,004,650 (+)NCBI
Rnor_5.049,966,483 - 10,005,809 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008762639   ⟹   XP_008760861
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.049,977,334 - 10,004,650 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017592516   ⟹   XP_017448005
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.049,968,441 - 10,004,650 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017592517   ⟹   XP_017448006
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2413,361,015 - 13,398,815 (+)NCBI
Rnor_6.049,966,859 - 10,004,650 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039107239   ⟹   XP_038963167
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2413,360,532 - 13,398,815 (+)NCBI
RefSeq Acc Id: XM_039107241   ⟹   XP_038963169
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2413,361,015 - 13,398,815 (+)NCBI
RefSeq Acc Id: XM_039107242   ⟹   XP_038963170
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2413,361,015 - 13,398,815 (+)NCBI
RefSeq Acc Id: XM_039107243   ⟹   XP_038963171
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2413,361,015 - 13,398,815 (+)NCBI
RefSeq Acc Id: XM_039107244   ⟹   XP_038963172
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2413,361,008 - 13,398,815 (+)NCBI
RefSeq Acc Id: XM_039107245   ⟹   XP_038963173
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2413,361,025 - 13,398,815 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_955413   ⟸   NM_199381
- UniProtKB: Q769K2 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006235970   ⟸   XM_006235908
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006235972   ⟸   XM_006235910
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_006235973   ⟸   XM_006235911
- Peptide Label: isoform X5
- UniProtKB: Q769K2 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_008760861   ⟸   XM_008762639
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_017448006   ⟸   XM_017592517
- Peptide Label: isoform X5
- UniProtKB: Q769K2 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017448005   ⟸   XM_017592516
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSRNOP00000073608   ⟸   ENSRNOT00000086609
RefSeq Acc Id: ENSRNOP00000015322   ⟸   ENSRNOT00000015322
RefSeq Acc Id: XP_038963167   ⟸   XM_039107239
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038963172   ⟸   XM_039107244
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038963169   ⟸   XM_039107241
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038963170   ⟸   XM_039107242
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038963171   ⟸   XM_039107243
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038963173   ⟸   XM_039107245
- Peptide Label: isoform X5
Protein Domains
Lactamase_B

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692818
Promoter ID:EPDNEW_R3332
Type:initiation region
Name:Napepld_1
Description:N-acyl phosphatidylethanolamine phospholipase D
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.049,966,894 - 9,966,954EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:735197 AgrOrtholog
Ensembl Genes ENSRNOG00000011363 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000015322 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000073608 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000015322 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000086609 UniProtKB/TrEMBL
Gene3D-CATH 3.60.15.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Metallo-B-lactamas UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NAPE-PLD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RibonucZ/Hydroxyglut_hydro UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:296757 UniProtKB/Swiss-Prot
NCBI Gene 296757 ENTREZGENE
Pfam Lactamase_B_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Napepld PhenoGen
PIRSF NAPE-PLD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF56281 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2K5Y7_RAT UniProtKB/TrEMBL
  NAPEP_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-04 Napepld  N-acyl phosphatidylethanolamine phospholipase D  NAPE-PLD  N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-09-30 NAPE-PLD        Symbol and Name status set to provisional 70820 PROVISIONAL