Napepld (N-acyl phosphatidylethanolamine phospholipase D) - Rat Genome Database

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Gene: Napepld (N-acyl phosphatidylethanolamine phospholipase D) Rattus norvegicus
Analyze
Symbol: Napepld
Name: N-acyl phosphatidylethanolamine phospholipase D
RGD ID: 735197
Description: Enables phospholipase activity. Involved in negative regulation of eating behavior; phospholipid metabolic process; and response to isolation stress. Predicted to be located in Golgi apparatus; early endosome; and nucleus. Predicted to be active in hippocampal mossy fiber to CA3 synapse; smooth endoplasmic reticulum membrane; and synaptic membrane. Biomarker of osteoarthritis. Orthologous to human NAPEPLD (N-acyl phosphatidylethanolamine phospholipase D); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D; NAPE-hydrolyzing phospholipase D; NAPE-PLD
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8414,251,591 - 14,291,010 (+)NCBIGRCr8
mRatBN7.2413,360,532 - 13,398,815 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl413,361,006 - 13,398,748 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx418,515,917 - 18,536,222 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0414,324,467 - 14,344,734 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0412,701,560 - 12,721,865 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.049,965,323 - 10,004,650 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl49,966,891 - 10,002,247 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.049,966,483 - 10,005,809 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.448,821,727 - 8,845,709 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.148,821,726 - 8,845,709 (+)NCBI
Celera48,954,741 - 8,975,084 (+)NCBICelera
Cytogenetic Map4q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. In vitro and in vivo models of Huntington's disease show alterations in the endocannabinoid system. Bari M, etal., FEBS J. 2013 Jul;280(14):3376-88. doi: 10.1111/febs.12329. Epub 2013 Jun 10.
2. Targeted enhancement of oleoylethanolamide production in proximal small intestine induces across-meal satiety in rats. Fu J, etal., Am J Physiol Regul Integr Comp Physiol. 2008 Jul;295(1):R45-50. doi: 10.1152/ajpregu.00126.2008. Epub 2008 Apr 23.
3. The endocannabinoid system is modulated in response to spinal cord injury in rats. Garcia-Ovejero D, etal., Neurobiol Dis. 2009 Jan;33(1):57-71. Epub 2008 Sep 30.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Age dependent accumulation of N-acyl-ethanolamine phospholipids in ischemic rat brain. A (31)P NMR and enzyme activity study. Moesgaard B, etal., J Lipid Res. 2000 Jun;41(6):985-90.
6. Molecular characterization of a phospholipase D generating anandamide and its congeners. Okamoto Y, etal., J Biol Chem 2004 Feb 13;279(7):5298-305. Epub 2003 Nov 21.
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Tonic modulation of spinal hyperexcitability by the endocannabinoid receptor system in a rat model of osteoarthritis pain. Sagar DR, etal., Arthritis Rheum. 2010 Dec;62(12):3666-76. doi: 10.1002/art.27698.
Additional References at PubMed
PMID:15249196   PMID:15992380   PMID:16818490   PMID:19056867   PMID:25684574   PMID:25757720  


Genomics

Comparative Map Data
Napepld
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8414,251,591 - 14,291,010 (+)NCBIGRCr8
mRatBN7.2413,360,532 - 13,398,815 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl413,361,006 - 13,398,748 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx418,515,917 - 18,536,222 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0414,324,467 - 14,344,734 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0412,701,560 - 12,721,865 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.049,965,323 - 10,004,650 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl49,966,891 - 10,002,247 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.049,966,483 - 10,005,809 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.448,821,727 - 8,845,709 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.148,821,726 - 8,845,709 (+)NCBI
Celera48,954,741 - 8,975,084 (+)NCBICelera
Cytogenetic Map4q11NCBI
NAPEPLD
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387103,099,776 - 103,150,001 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7103,099,776 - 103,149,560 (-)EnsemblGRCh38hg38GRCh38
GRCh377102,740,223 - 102,790,448 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367102,527,459 - 102,576,741 (-)NCBINCBI36Build 36hg18NCBI36
Celera797,547,949 - 97,597,471 (-)NCBICelera
Cytogenetic Map7q22.1NCBI
HuRef797,103,121 - 97,152,369 (-)NCBIHuRef
CHM1_17102,673,431 - 102,722,953 (-)NCBICHM1_1
T2T-CHM13v2.07104,414,920 - 104,465,123 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27102,100,389 - 102,149,935 (-)NCBI
Napepld
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39521,867,899 - 21,906,620 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl521,867,899 - 21,906,394 (-)EnsemblGRCm39 Ensembl
GRCm38521,662,901 - 21,701,622 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl521,662,901 - 21,701,396 (-)EnsemblGRCm38mm10GRCm38
MGSCv37521,168,721 - 21,207,163 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36521,174,727 - 21,213,169 (-)NCBIMGSCv36mm8
Celera518,631,024 - 18,671,982 (-)NCBICelera
Cytogenetic Map5A3NCBI
cM Map59.97NCBI
Napepld
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554108,220,400 - 8,247,486 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554108,217,684 - 8,233,302 (-)NCBIChiLan1.0ChiLan1.0
NAPEPLD
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26139,942,431 - 140,005,769 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17188,214,784 - 188,269,643 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0795,074,084 - 95,123,936 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17107,923,952 - 107,973,269 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7107,923,960 - 107,973,269 (-)Ensemblpanpan1.1panPan2
NAPEPLD
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11816,945,096 - 16,990,752 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1816,945,253 - 17,009,607 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1816,599,554 - 16,650,199 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01817,253,389 - 17,307,355 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1817,253,376 - 17,307,330 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11817,011,890 - 17,062,566 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01816,950,687 - 17,001,305 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01817,219,297 - 17,269,945 (+)NCBIUU_Cfam_GSD_1.0
Napepld
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511859,135,563 - 59,172,683 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647920,275,319 - 20,292,688 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647920,259,260 - 20,293,116 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NAPEPLD
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9103,210,748 - 103,262,910 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19103,210,655 - 103,309,018 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29113,620,593 - 113,632,997 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NAPEPLD
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12172,174,451 - 72,224,932 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2172,178,041 - 72,224,559 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604231,777,904 - 31,826,799 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Napepld
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473926,117,665 - 26,152,322 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Napepld
256 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:83
Count of miRNA genes:75
Interacting mature miRNAs:79
Transcripts:ENSRNOT00000015322
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2302371Stl22Serum triglyceride level QTL 225.15blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521829457114705Rat
8552903Pigfal2Plasma insulin-like growth factor 1 level QTL 27.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)4131934116Rat
724557Plsm1Polydactyly-luxate syndrome (PLS) morphotypes QTL 10.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)4127716890Rat
9590100Sffal4Serum free fatty acids level QTL 47.360.05blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)4131934116Rat
8552906Pigfal3Plasma insulin-like growth factor 1 level QTL 3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)41008408955084089Rat
1357341Gluco5Glucose level QTL 56.4adipocyte free fatty acid secretion trait (VT:0010465)absolute change in adipocyte free fatty acid secretion per unit volume (CMO:0001446)4133250345Rat
1357343Gluco4Glucose level QTL 40.00002adipocyte glucose uptake trait (VT:0004185)adipocyte maximal glucose uptake to basal glucose uptake ratio (CMO:0000874)4133250345Rat
6478766Anxrr47Anxiety related response QTL 470.09637locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)41008408955084089Rat
631642Stl2Serum triglyceride level QTL 23.3blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521917856647776Rat
6478769Anxrr48Anxiety related response QTL 480.02514locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)41008408955084089Rat
631261Tcas3Tongue tumor susceptibility QTL 36.88tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)41081417091360527Rat
61333Gluco16Glucose level QTL 164.30.00001adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)4130372989Rat
634323Hc2Hypercalciuria QTL 22.15urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)421079645210796Rat
631209Bw2Body weight QTL24.2retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)4994088544463908Rat
61408Scl23Serum cholesterol level QTL 230.0005blood HDL phospholipid amount (VT:0010504)serum high density lipoprotein phospholipid level (CMO:0001567)4127716890Rat
8694374Bw155Body weight QTL 1553.390.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)41008408955084089Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45214602146446691Rat
9589046Scfw2Subcutaneous fat weight QTL 25.540.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)4131934116Rat
6478724Anxrr35Anxiety related response QTL 350.00449defecation behavior trait (VT:0010462)defecation measurement (CMO:0000997)41008408955084089Rat
61351Bp33Blood pressure QTL 330.0018arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4127716890Rat
61415Eae11Experimental allergic encephalomyelitis QTL 112.9nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)4139505420Rat
1641905Colcr1Colorectal carcinoma resistance QTL 14.30.0003intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)4129494328Rat
619616Bp79Blood pressure QTL 790.0292arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4521460278882945Rat
1358201Gluco12Glucose level QTL121.6adipocyte glucose uptake trait (VT:0004185)adipocyte maximal glucose uptake (CMO:0000870)4521839229593287Rat
738021Hcar13Hepatocarcinoma resistance QTL 134.3liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)4132584199Rat
1358203Stl19Serum triglyceride level QTL 192.80.002blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521829465958103Rat
9590304Scort17Serum corticosterone level QTL 174.960.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)41008408955084089Rat
9589097Slep11Serum leptin concentration QTL 115.090.001blood leptin amount (VT:0005667)plasma leptin level (CMO:0000781)4131934116Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
1300141Bp178Blood pressure QTL 178arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)41002490139524530Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000015322   ⟹   ENSRNOP00000015322
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl413,370,975 - 13,398,748 (+)Ensembl
Rnor_6.0 Ensembl49,981,958 - 10,002,247 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000086609   ⟹   ENSRNOP00000073608
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl413,361,006 - 13,398,748 (+)Ensembl
Rnor_6.0 Ensembl49,966,891 - 9,997,267 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000104090   ⟹   ENSRNOP00000082713
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl413,361,026 - 13,398,748 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000116230   ⟹   ENSRNOP00000082705
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl413,361,026 - 13,398,748 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000117324   ⟹   ENSRNOP00000094226
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl413,361,031 - 13,398,748 (+)Ensembl
RefSeq Acc Id: NM_199381   ⟹   NP_955413
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8414,253,260 - 14,291,010 (+)NCBI
mRatBN7.2413,361,046 - 13,398,803 (+)NCBI
Rnor_6.049,981,958 - 10,002,247 (+)NCBI
Rnor_5.049,966,483 - 10,005,809 (+)NCBI
RGSC_v3.448,821,727 - 8,845,709 (+)RGD
Celera48,954,741 - 8,975,084 (+)RGD
Sequence:
RefSeq Acc Id: XM_006235908   ⟹   XP_006235970
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8414,251,591 - 14,291,010 (+)NCBI
mRatBN7.2413,360,532 - 13,398,815 (+)NCBI
Rnor_6.049,965,323 - 10,004,650 (+)NCBI
Rnor_5.049,966,483 - 10,005,809 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006235910   ⟹   XP_006235972
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8414,253,223 - 14,291,010 (+)NCBI
mRatBN7.2413,361,015 - 13,398,815 (+)NCBI
Rnor_6.049,966,859 - 10,004,650 (+)NCBI
Rnor_5.049,966,483 - 10,005,809 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039107244   ⟹   XP_038963172
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8414,253,216 - 14,291,010 (+)NCBI
mRatBN7.2413,361,008 - 13,398,815 (+)NCBI
RefSeq Acc Id: XM_063285707   ⟹   XP_063141777
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8414,267,298 - 14,291,010 (+)NCBI
RefSeq Acc Id: XM_063285708   ⟹   XP_063141778
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8414,266,297 - 14,291,010 (+)NCBI
RefSeq Acc Id: NP_955413   ⟸   NM_199381
- UniProtKB: Q769K2 (UniProtKB/Swiss-Prot),   A6K5B2 (UniProtKB/TrEMBL),   A0A8I6AKD5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006235970   ⟸   XM_006235908
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AKD5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006235972   ⟸   XM_006235910
- Peptide Label: isoform X2
- UniProtKB: A0A0G2K5Y7 (UniProtKB/TrEMBL),   A0A8I6AKD5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000073608   ⟸   ENSRNOT00000086609
Ensembl Acc Id: ENSRNOP00000015322   ⟸   ENSRNOT00000015322
RefSeq Acc Id: XP_038963172   ⟸   XM_039107244
- Peptide Label: isoform X3
- UniProtKB: Q769K2 (UniProtKB/Swiss-Prot),   A6K5B2 (UniProtKB/TrEMBL),   A0A8I6AKD5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000094226   ⟸   ENSRNOT00000117324
Ensembl Acc Id: ENSRNOP00000082705   ⟸   ENSRNOT00000116230
Ensembl Acc Id: ENSRNOP00000082713   ⟸   ENSRNOT00000104090
RefSeq Acc Id: XP_063141778   ⟸   XM_063285708
- Peptide Label: isoform X3
- UniProtKB: Q769K2 (UniProtKB/Swiss-Prot),   A6K5B2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141777   ⟸   XM_063285707
- Peptide Label: isoform X3
- UniProtKB: Q769K2 (UniProtKB/Swiss-Prot),   A6K5B2 (UniProtKB/TrEMBL)
Protein Domains
Metallo-beta-lactamase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q769K2-F1-model_v2 AlphaFold Q769K2 1-396 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692818
Promoter ID:EPDNEW_R3332
Type:initiation region
Name:Napepld_1
Description:N-acyl phosphatidylethanolamine phospholipase D
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.049,966,894 - 9,966,954EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:735197 AgrOrtholog
BioCyc Gene G2FUF-45982 BioCyc
Ensembl Genes ENSRNOG00000011363 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000015322.4 UniProtKB/TrEMBL
  ENSRNOT00000086609.2 UniProtKB/TrEMBL
  ENSRNOT00000104090.1 UniProtKB/TrEMBL
  ENSRNOT00000116230.1 UniProtKB/Swiss-Prot
  ENSRNOT00000117324.1 UniProtKB/TrEMBL
Gene3D-CATH 3.60.15.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Metallo-B-lactamas UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NAPE-PLD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RibonucZ/Hydroxyglut_hydro UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:296757 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 296757 ENTREZGENE
PANTHER N-ACYL-PHOSPHATIDYLETHANOLAMINE-HYDROLYZING PHOSPHOLIPASE D UniProtKB/Swiss-Prot
  N-ACYL-PHOSPHATIDYLETHANOLAMINE-HYDROLYZING PHOSPHOLIPASE D UniProtKB/Swiss-Prot
  N-ACYL-PHOSPHATIDYLETHANOLAMINE-HYDROLYZING PHOSPHOLIPASE D UniProtKB/TrEMBL
  N-ACYL-PHOSPHATIDYLETHANOLAMINE-HYDROLYZING PHOSPHOLIPASE D UniProtKB/TrEMBL
Pfam Lactamase_B_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Napepld PhenoGen
PIRSF NAPE-PLD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000011363 RatGTEx
Superfamily-SCOP SSF56281 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2K5Y7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AKD5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6G7S2_RAT UniProtKB/TrEMBL
  A0A8L2Q779_RAT UniProtKB/TrEMBL
  A6K5B2 ENTREZGENE, UniProtKB/TrEMBL
  NAPEP_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-04 Napepld  N-acyl phosphatidylethanolamine phospholipase D  NAPE-PLD  N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-09-30 NAPE-PLD        Symbol and Name status set to provisional 70820 PROVISIONAL