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Gene: Aicda (activation-induced cytidine deaminase) Rattus norvegicus
Symbol: Aicda
Name: activation-induced cytidine deaminase
RGD ID: 1303222
Description: Predicted to have several functions, including hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines; identical protein binding activity; and ubiquitin protein ligase binding activity. Predicted to be involved in several processes, including nucleic acid metabolic process; regulation of cellular macromolecule biosynthetic process; and response to bacterium. Predicted to localize to P-body; nucleus; and protein-containing complex. Human ortholog(s) of this gene implicated in hyperimmunoglobulin syndrome and immunodeficiency with hyper-IgM type 2. Orthologous to human AICDA (activation induced cytidine deaminase); PARTICIPATES IN interleukin-4 signaling pathway; primary immunodeficiency pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AID; single-stranded DNA cytosine deaminase
Homo sapiens (human) : AICDA (activation induced cytidine deaminase)  HGNC  Alliance
Mus musculus (house mouse) : Aicda (activation-induced cytidine deaminase)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : AICDA (activation induced cytidine deaminase)
Canis lupus familiaris (dog) : AICDA (activation induced cytidine deaminase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Aicda (activation induced cytidine deaminase)
Sus scrofa (pig) : AICDA (activation induced cytidine deaminase)
Chlorocebus sabaeus (African green monkey) : AICDA (activation induced cytidine deaminase)
Heterocephalus glaber (naked mole-rat) : Aicda (activation induced cytidine deaminase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.04155,359,909 - 155,371,104 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4155,359,921 - 155,369,671 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04222,384,433 - 222,395,569 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44159,006,328 - 159,017,501 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14159,257,307 - 159,260,429 (+)NCBI
Celera4144,595,276 - 144,605,030 (+)NCBICelera
Cytogenetic Map4q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Aicda
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1303222
Created: 2004-12-03
Species: Rattus norvegicus
Last Modified: 2020-10-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.