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Gene: Aicda (activation-induced cytidine deaminase) Rattus norvegicus
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Symbol: Aicda
Name: activation-induced cytidine deaminase
Description: Predicted to have several functions, including hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines; identical protein binding activity; and ubiquitin protein ligase binding activity. Predicted to be involved in several processes, including nucleic acid metabolic process; regulation of cellular macromolecule biosynthetic process; and response to bacterium. Predicted to localize to the P-body; nucleus; and protein-containing complex. Human ortholog(s) of this gene implicated in hyperimmunoglobulin syndrome and immunodeficiency with hyper-IgM type 2. Orthologous to human AICDA (activation induced cytidine deaminase); PARTICIPATES IN interleukin-4 signaling pathway; primary immunodeficiency pathway; INTERACTS WITH acrylamide; bisphenol A; manganese(II) chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AID; single-stranded DNA cytosine deaminase
Orthologs:
Homo sapiens (human) : AICDA (activation induced cytidine deaminase)  HGNC  Alliance
Mus musculus (house mouse) : Aicda (activation-induced cytidine deaminase)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : AICDA (activation induced cytidine deaminase)
Canis lupus familiaris (dog) : AICDA (activation induced cytidine deaminase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Aicda (activation induced cytidine deaminase)
Sus scrofa (pig) : AICDA (activation induced cytidine deaminase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.04155,359,909 - 155,371,104 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4155,359,921 - 155,369,671 (+)Ensembl
Rnor_5.04222,384,433 - 222,395,569 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44159,006,328 - 159,017,501 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14159,257,307 - 159,260,429 (+)NCBI
Celera4144,595,276 - 144,605,030 (+)NCBICelera
Cytogenetic Map4q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Aicda
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1303222
Created: 2004-12-03
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.