Eae20 QTL Report (Rattus norvegicus) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
QTL Registration

QTL: Eae20 (Experimental allergic encephalomyelitis QTL 20) Rattus norvegicus

Symbol: Eae20
Name: Experimental allergic encephalomyelitis QTL 20
RGD ID: 1581574
Trait: nervous system integrity trait   (VT:0010566)    
Measurement Type: percentage of study population developing experimental autoimmune encephalomyelitis during a period of time   (CMO:0001047)    
LOD Score: 7.8
P Value: Not Available
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24153,031,106 - 158,841,762RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.04152,482,121 - 158,564,471RGD_MAPPER_PIPELINERnor6.0
Rnor_5.04219,525,801 - 225,566,369RGDRnor5.0
RGSC_v3.44155,974,180 - 162,362,144RGDRGSC3.4
RGSC_v3.14156,219,116 - 162,607,080RGD
Cross Type: Not Available
Strains Crossed: DA PVG.1AV1 



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
Eae20Ratpercentage of study population developing experimental autoimmune encephalomyelitis during a period of time  IDA 1547849 RGD 

Experimental Condition
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
Eae20RatFreund's incomplete adjuvant  IDA 1547849 RGD 
Eae20Ratmyelin oligodendrocyte glycoprotein  IDA 1547849intradermal injection 20ug/ratRGD 

Measurement Method
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
Eae20Ratin vivo visual assessment  IDA 1547849 RGD 

Rat Strain
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
Eae20RatDA  IEA 1547849 RGD 
Eae20RatPVG.1AV1  IEA 1547849 RGD 

Vertebrate Trait
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
Eae20Ratnervous system integrity trait  IDA 1547849 RGD 

Disease Annotations     Click to see Annotation Detail View

Experimental Data Annotations     Click to see Annotation Detail View

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain
DA  (IEA)
PVG.1AV1  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Resolution of a 16.8-Mb autoimmunity-regulating rat chromosome 4 region into multiple encephalomyelitis quantitative trait loci and evidence for epistasis. Jagodic M, etal., J Immunol 2005 Jan 15;174(2):918-24.

Region

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
Position Markers

Flank 1: (D14Rat113)
Rat AssemblyChrPosition (strand)Source
RH 2.0 Map14174.1RGD
SHRSP x BN Map146.9RGD
Peak: (D4Mgh10)
Rat AssemblyChrPosition (strand)Source
mRatBN7.24155,936,364 - 155,936,504 (+)MAPPER
Rnor_6.04155,523,227 - 155,523,366NCBI
Rnor_5.04222,546,016 - 222,546,155UniSTS
RGSC_v3.44159,168,093 - 159,168,232UniSTS
RGSC_v3.44159,168,092 - 159,168,232RGD
Celera4144,755,177 - 144,755,316UniSTS
RGSC_v3.14159,413,028 - 159,413,168RGD
Cytogenetic Map4 RGD
Flank 2: (D4Got132)
Rat AssemblyChrPosition (strand)Source
mRatBN7.24158,841,508 - 158,841,762 (+)MAPPER
Rnor_6.04158,564,220 - 158,564,471NCBI
Rnor_5.04225,566,118 - 225,566,369UniSTS
RGSC_v3.44162,361,893 - 162,362,144UniSTS
RGSC_v3.44162,361,892 - 162,362,144RGD
Celera4147,567,471 - 147,567,722UniSTS
RGSC_v3.14162,606,829 - 162,607,080RGD
RH 3.4 Map41002.1UniSTS
RH 3.4 Map41002.1RGD


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_statistics_details QTL also linked to onset of disease, change in body weight, and severity of disease 1547849